5’-O-DMTr-5-iodo-2’-deoxyuridine

Catalog No.: A55392
Purine Nucleoside Analog
5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable tool in cancer research, aiding in the exploration of therapeutic strategies targeting nucleic acid metabolism and cellular proliferation.
Grouped product items
Size Price Stock Qty
1g
$75.00
In stock
5g
$175.00
In stock
10g
$265.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable tool in cancer research, aiding in the exploration of therapeutic strategies targeting nucleic acid metabolism and cellular proliferation.
Product Information
Catalog NumA55392
FormulaC30H29IN2O7
Molecular Weight656.46
CAS Number104375-88-4
SMILESCOC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@H]4O[C@@H](N5C(NC(C(I)=C5)=O)=O)C[C@@H]4O
Synonyms2'-Deoxy-5'-O-DMT-5-iodouridine
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