Documents & Downloads

DFP-11207

Anticancer Agent

DFP-11207 is an orally active fluoropyrimidine cytotoxic agent designed to target and enhance the pharmacological activity of 5-fluorouracil (5-FU). It functions as a pro-drug that incorporates a reversible dihydropyrimidine dehydrogenase (DPD) inhibitor and a potent orotate phosphoribosyltransferase (OPRT) inhibitor, which together mitigate gastrointestinal and myelosuppressive toxicities associated with traditional 5-FU therapy. DFP-11207 is primarily utilized in cancer research, providing insights into more effective and safer chemotherapeutic strategies.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1296177-16-6
Applications	Anticancer Agent
Formula	C₃₂H₂₆ClFN₄O₁₂
Molecular Weight	713.02
SMILES	O=C(C1=CC(OC(CC)=O)=NC(OC(CC)=O)=C1)OC2=CC(OC(C3=CC=CC(C(N(C(N(COCC)C=C4F)=O)C4=O)=O)=C3)=O)=NC=C2Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.