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N1-Propargylpseudouridine

Purine Nucleoside Analog

N1-Propargylpseudouridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and induction of apoptosis, contributing to its efficacy in cancer research. Additionally, N1-Propargylpseudouridine functions as a click chemistry reagent, possessing an alkyne group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating various biochemical applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1464021-70-2
Applications	Purine Nucleoside Analog
Formula	C₁₂H₁₄N₂O₆
Molecular Weight	282.25
SMILES	O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(CC#C)C2=O)O[C@@H]1CO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.