2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog that serves as a vital tool in chemical biology research. This compound exhibits notable anti-inflammatory properties and functions as a potential endogenous inhibitor of poly(ADP-ribose) polymerase (PARP), contributing to cytoprotection by restraining PARP activity and preventing peroxynitrite-induced mitochondrial depolarization. Additionally, its role as a hypoxia indicator makes it valuable for studies involving cellular stress responses and metabolic conditions.
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog that serves as a vital tool in chemical biology research. This compound exhibits notable anti-inflammatory properties and functions as a potential endogenous inhibitor of poly(ADP-ribose) polymerase (PARP), contributing to cytoprotection by restraining PARP activity and preventing peroxynitrite-induced mitochondrial depolarization. Additionally, its role as a hypoxia indicator makes it valuable for studies involving cellular stress responses and metabolic conditions.
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