Fig. 1 · Structure
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2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite
Hypoxanthine Analog
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog that serves as a vital tool in chemical biology research. This compound exhibits notable anti-inflammatory properties and functions as a potential endogenous inhibitor of poly(ADP-ribose) polymerase (PARP), contributing to cytoprotection by restraining PARP activity and preventing peroxynitrite-induced mitochondrial depolarization. Additionally, its role as a hypoxia indicator makes it valuable for studies involving cellular stress responses and metabolic conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2245842-16-2 |
| Applications | Hypoxanthine Analog |
| Formula | C40H46FN6O7P |
| Molecular Weight | 772.80 |
| SMILES | COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@H](N5C(NC=NC6=O)=C6N=C5)O4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.