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5’-O-DMTr-2’-OMeU-methyl phosphonamidite

Purine Nucleoside Analog

5’-O-DMTr-2’-OMeU-methyl phosphonamidite is a purine nucleoside analog that effectively targets DNA synthesis to exert antitumor activity. This compound induces apoptosis and demonstrates potential in treating indolent lymphoid malignancies, making it a valuable tool for cancer research. It is applicable in the design and synthesis of therapeutic oligonucleotides and other nucleic acid-based applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	191786-64-8
Applications	Purine Nucleoside Analog
Formula	C₃₈H₄₈N₃O₈P
Molecular Weight	705.78
SMILES	O=C1C=CN([C@H]2[C@H](OC)[C@H](OP(N(C(C)C)C(C)C)C)[C@@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)O2)C(N1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.