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Guanosine 5'-triphosphate-5'-adenosine

Fluorescent Substrate Analog

Guanosine 5'-triphosphate-5'-adenosine (GpppA) serves as a fluorescent substrate analog targeting RNA synthesis in vitro. As a 5′ cap analog, it plays a pivotal role in facilitating the incorporation of nucleotides during RNA transcription and can be utilized in various research applications, including studies of mRNA capping and translation initiation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	10527-47-6
Applications	Fluorescent Substrate Analog
Formula	C₂₀H₂₇N₁₀O₁₇P₃
Molecular Weight	772.41
Synonyms	GpppA
SMILES	O=P(O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C(N)N=CN=C23)O1)OP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C(NC(N)=N6)=C(N=C5)C6=O)O4)(O)=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.