Fig. 1 · Structure
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Geldanamycin-FITC
Geldanamycin Fluorescent Probe
Geldanamycin-FITC is a fluorescent probe that specifically targets HSP90. This compound enables the evaluation of HSP90 inhibitors through fluorescence polarization assays and can effectively detect cell surface HSP90 with an excitation/emission wavelength of 488/515 nm. It serves as a valuable tool in understanding HSP90-related biological processes and evaluating therapeutic interventions in diseases associated with this chaperone protein.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2969156-01-0 |
| Applications | Geldanamycin Fluorescent Probe |
| Formula | C55H63N5O13S |
| Molecular Weight | 1034.18 |
| SMILES | O=C(C(NCCCCCCNC(NC1=CC=C(C(C(C=CC(O)=C2)=C2O3)=C4C3=CC(C=C4)=O)C(C(O)=O)=C1)=S)=C5C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C6C)C=C(NC(/C(C)=C/C=C\[C@H](OC)[C@H]\6OC(N)=O)=O)C5=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.