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Complex 3

Fluorescent Dye

Complex 3 is a fluorescent dithiocarbazate-copper complex targeting mitochondrial function, demonstrating significant anticancer properties. It exhibits excitation and emission maxima of 455-495 nm and 535 nm, respectively. Complex 3 effectively inhibits the proliferation of several pancreatic cancer cell lines, including BxPC-3, AsPC-1, PANC-1, and WI38, with IC50 values of 0.74, 0.41, 0.62, and 2.06 µM, respectively. Additionally, it induces lipid peroxidation, mitochondrial rupture, and apoptosis, while also disrupting cytokine-cytokine receptor interactions in AsPC-1 cells. In vivo, Complex 3 has demonstrated efficacy by reducing tumor volume in an AsPC-1 mouse xenograft model, making it a valuable tool for cancer research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2480150-28-3
Applications	Fluorescent Dye
Formula	C₂₆H₂₂Br₃Cu₃N₈S₄
Molecular Weight	1005.12
SMILES	[Br-][Cu+2]1([S-]2)[N](N=C2SC)=C(C3=CC=CC=[N]3[Cu+]([N]4=CC=CC=C4C(C5=CC=CC=[N]56)=[N](N=C7SC)[Cu+2]6([S-]7)[Br-])[Br-])C8=CC=CC=[N]81

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.