Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Adipic acid-d4 is a deuterium-labeled derivative of adipic acid (hexanedioic acid) primarily used as a stable isotope in research applications. This compound exhibits low toxicity and is valued for its role as a food additive and gelling agent. Additionally, adipic acid is involved in the synthesis of various industrial materials, including lubricants, artificial resins, and plastics, making it relevant for studies in both biochemical and materials science fields. -
Stable Isotope
Adipic acid-13C6 is a stable isotope-labeled form of hexanedioic acid. This compound serves as a valuable tool in metabolic studies and tracer experiments due to its stable carbon isotope labeling. Adipic acid is recognized for its minimal toxicity and offers broad applications, including as a food additive and gelling agent, as well as in the synthesis of lubricants and plastics. Its unique isotopic properties make it suitable for applications in both biochemical and environmental research. -
Stable Isotope
Adipic acid-d8 is a deuterium-labeled variant of adipic acid (hexanedioic acid), serving as a stable isotope for research applications. This compound exhibits anti-HSV-1 activity and possesses low toxicity, making it suitable for various biological studies. Adipic acid-d8 can be utilized in the synthesis of lubricants, artificial resins, and plastics, as well as in food additive applications, thereby supporting investigations in both chemical and pharmaceutical research. -
Stable Isotope
Adipic acid-13C is a stable isotope-labeled form of adipic acid (hexanedioic acid) that serves as a valuable tracer in metabolic studies. This compound exhibits anti-HSV-1 activity and is recognized for its low toxicity, making it suitable for various applications, including food additives and gelling agents. Additionally, adipic acid-13C is utilized in the synthesis of lubricants, artificial resins, and plastics, facilitating research in biochemistry and materials science. -
Stable Isotope
Adipic acid-d10 is a stable isotope-labeled derivative of adipic acid (hexanedioic acid), serving as a valuable tool in chemical research. This compound maintains its anti-HSV-1 activity and low toxicity profile, making it suitable for various biological studies. Additionally, adipic acid-d10 can be utilized in synthetic applications for lubricants, artificial resins, and plastics, facilitating research in polymer chemistry and materials science. -
Stable Isotope
Levamisole-d5 hydrochloride is a deuterium-labeled analog of Levamisole hydrochloride, a synthetic imidazothiazole derivative. This compound acts as an anthelmintic and immunomodulator, exhibiting significant biological activity against various targets. Research applications include the study of its immunomodulatory effects and antiviral properties, particularly against herpes simplex virus (HSV). -
Stable Isotope
Penciclovir-d4 is a deuterium-labeled derivative of Penciclovir, primarily targeting the herpes simplex virus (HSV). This stable isotope enables precise tracking and analysis in various biological studies. Penciclovir has demonstrated significant antiviral activity against HSV types 1 and 2, with reported IC50 values ranging from 0.04 to 1.8 μg/mL and 0.06 to 4.4 μg/mL, respectively. It is suitable for research applications focused on viral pathogenesis and therapeutic development. -
Stable Isotope
3-Indoleacetonitrile-d4 is a deuterated derivative of 3-Indoleacetonitrile, functioning as a stable isotope. This compound exhibits significant antiviral activity, particularly against a range of influenza A viruses, HSV-1, and VSV in vitro. Notably, it reduces lung virus titers and mitigates lung lesions in vivo, while also promoting an increase in mitochondrial antiviral-signaling (MAVS) protein levels. 3-Indoleacetonitrile-d4 serves as a valuable tool in research aimed at understanding and combating viral infections, including COVID-19, HSV-1, and VSV. -
Stable Isotope
Famciclovir-d4 is a deuterated form of the antiviral agent Famciclovir, which acts as a guanine analogue. This stable isotope is primarily utilized in pharmacokinetic studies and metabolic research involving Famciclovir. Its unique labeling allows for enhanced tracking and analysis of drug metabolism and distribution in biological systems, contributing to a deeper understanding of herpesvirus infections and their treatment. -
Stable Isotope
Trifluridine-13C,15N2 is a stable isotope-labeled form of Trifluridine, which functions as an irreversible inhibitor of thymidylate synthase, leading to inhibition of DNA synthesis. This compound exhibits antiviral activity against herpes simplex virus (HSV) infections and possesses anti-orthopoxvirus properties. Trifluridine-13C,15N2 is utilized in research applications involving metabolic studies and the tracking of nucleic acid synthesis in cellular processes. -
Stable Isotope
Adipic acid-13C2 is a stable isotope-labeled derivative of adipic acid (hexanedioic acid), incorporating two carbon-13 atoms. This compound is utilized primarily in metabolic studies and tracer experiments due to its stable isotope labeling, allowing for improved analysis in biological systems. Adipic acid exhibits low toxicity and demonstrates potential applications as a food additive and gelling agent, while also serving as a precursor in the synthesis of lubricants, artificial resins, and plastics. -
Stable Isotope
Adipic acid-d44-1 is a deuterium-labeled derivative of adipic acid, primarily serving as a stable isotope reagent. This compound enables precise tracking and quantification in metabolic studies and chemical syntheses. Adipic acid exhibits low toxicity and is commonly utilized as a food additive, gelling agent, and in the production of lubricants, artificial resins, and plastics. Its stable isotope form facilitates advanced analytical techniques in various research applications. -
Stable Isotope
N6-Methyladenosine-d3 is a deuterated stable isotope of N6-Methyladenosine, a key internal modification in messenger RNA (mRNA) across higher eukaryotes. This modification plays a significant role in various biological processes, including gene expression regulation and RNA stability. N6-Methyladenosine-d3 can also interact with viral RNAs, demonstrating potential antiviral activities. Its applications include studies in RNA biology and epitranscriptomics, enabling researchers to explore the dynamics and functions of RNA modifications in cellular processes. -
Stable Isotope
DL-Pyroglutamic acid-d5 is a deuterium-labeled form of DL-Pyroglutamic acid, serving as a stable isotope. It is used in various analytical techniques, including nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry, to trace metabolic pathways and study amino acid metabolism. This reagent is valuable for researchers investigating biochemical processes involving pyroglutamic acid and its derivatives. -
Stable Isotope
Coumarin-d4 is a deuterium-labeled analog of Coumarin, a compound recognized for its diverse biological activities. This stable isotope is utilized in pharmacological research to trace metabolic pathways and enhance analytical sensitivity. Coumarin exhibits significant anticancer, anti-inflammatory, and antiviral properties, making this labeled variant particularly valuable for studies involving its mechanism of action and therapeutic potential. -
Stable Isotope
Oseltamivir acid-d3 is a deuterium-labeled derivative of Oseltamivir acid, which serves as the active metabolite of Oseltamivir phosphate. This compound acts as a highly selective inhibitor of influenza virus neuraminidase, exhibiting an IC50 of 2 nM against both influenza A and B viruses. While its ability to cross the blood-brain barrier is limited under normal physiological conditions, penetration is notably increased during inflammatory states, making it a valuable reagent for studying antiviral mechanisms and neuroinflammation in research applications. -
Stable Isotope
Palmitoylethanolamide-d4 is a deuterated analog of Palmitoylethanolamide, a naturally occurring fatty acid amide. This stable isotope is utilized in research to study the pharmacokinetics and biological effects of Palmitoylethanolamide. Key applications include investigations into its role in modulating inflammation and its potential therapeutic effects in respiratory viral infections. -
Stable Isotope
Oseltamivir-d5 is a deuterated derivative of Oseltamivir, a neuraminidase inhibitor that targets the influenza virus. It exhibits potent antiviral activity against various strains of influenza, including A/H3N2, A/H1N2, A/H1N1, and B, with mean IC50 values of 0.67, 0.9, 1.34, and 13 nM, respectively. This stable isotope-labeled compound is valuable for pharmacokinetic studies and research applications focusing on influenza virus dynamics and drug metabolism. -
Stable Isotope
Palmitoylethanolamide-d5 is a deuterated stable isotope of Palmitoylethanolamide, an endogenous compound known for its role in modulating inflammation and pain. Its biological activity includes potential antiviral effects, particularly in preventing respiratory tract infections. This compound is valuable for research applications involving metabolic studies and the investigation of lipid signaling pathways. -
Stable Isotope
L-Norleucine-d9 is the deuterium-labeled variant of L-Norleucine, a non-proteinogenic amino acid that specifically impacts protein synthesis in skeletal muscle. This stable isotope is valuable for studying metabolic pathways and post-translational modifications in protein research. Additionally, L-Norleucine exhibits antiviral activity, making it applicable in virology studies and therapeutic research. -
Stable Isotope
Baloxavir-d1 is a deuterium-labeled derivative of Baloxavir, a first-in-class, potent, and selective cap-dependent endonuclease inhibitor targeting the polymerase PA subunit of influenza A and B viruses. This reagent functions to inhibit viral RNA transcription and replication, demonstrating significant antiviral activity. Baloxavir-d1 is valuable in biological research, particularly in studies focused on influenza virus mechanisms and the development of antiviral therapies. -
Stable Isotope
N-Acetylneuraminic acid-13C-1 is a stable isotope-labeled form of N-Acetylneuraminic acid, which serves as a key sialic acid component in glycoproteins and glycolipids. This compound is instrumental in metabolic studies and tracing pathways in carbohydrate metabolism. It is widely used in research to explore cell signaling, immune response, and interactions involving sialic acids in various biological contexts. -
Stable Isotope
N-Acetylneuraminic acid-13C-2 is a stable isotope-labeled form of N-Acetylneuraminic acid, designated for use in metabolic and biochemical research. This compound serves as a valuable tracer in studies of sialic acid metabolism and its role in cellular processes. Its incorporation into biomolecules allows for advanced imaging and analysis, contributing to a deeper understanding of glycan dynamics in various biological systems. -
Stable Isotope
N-Acetylneuraminic acid-13C is a stable isotope-labeled form of N-Acetylneuraminic acid, which serves as a crucial component of glycoproteins and glycolipids. This compound is primarily utilized in metabolic studies and tracing experiments to investigate sialic acid's role in cellular interactions and signaling. The incorporation of the 13C label allows for precise tracking of this biomolecule in various biological systems, facilitating further research in cell biology, immunology, and microbiology. -
Stable Isotope
Oseltamivir-13C,d3 phosphate is a stable isotope-labeled form of Oseltamivir phosphate, a potent neuraminidase inhibitor. It effectively targets the influenza virus, making it useful for both treatment and prophylaxis of influenza A and B. This compound is valuable for research applications requiring isotopic labeling in pharmacokinetics and metabolic studies. -
Stable Isotope
N-Desethyl amodiaquine-d5 is a deuterium-labeled analog of N-Desethyl amodiaquine, the principal active metabolite of Amodiaquine. This compound exhibits significant antiparasitic activity, with IC50 values of 97 nM against V1/S strains and 25 nM against 3D7 strains. It is utilized in studies focused on the pharmacokinetics and dynamics of antimalarial therapies, making it an essential tool for researchers in malaria treatment and related fields. -
Stable Isotope
Artemether-d3 is the deuterium-labeled derivative of Artemether, designed as a stable isotope for research applications. Artemether is widely recognized for its efficacy as an antimalarial agent, particularly against resistant strains of Plasmodium falciparum. This compound is essential for pharmacokinetic studies and metabolic research involving Artemether, enabling scientists to trace its pharmacological pathways and enhance understanding of its therapeutic mechanisms. -
Stable Isotope
Permethrin-d5 is a deuterium-labeled analog of Permethrin, which acts primarily as a neurotoxic insecticide and acaricide. By prolonging sodium channel activation, it disrupts neuronal function in target species. This stable isotope is useful for studying metabolic pathways and environmental fate in chemical research applications. -
Stable Isotope
Thiabendazole-d4 is a deuterated derivative of Thiabendazole, a compound known for its antiseptic, antifungal, and antiparasitic properties. This stable isotope is primarily utilized in metabolic studies and quantitative analysis of Thiabendazole metabolism and pharmacokinetics. Its incorporation allows for enhanced sensitivity and accuracy in mass spectrometry applications, aiding in the investigation of drug interactions and biological pathways involving this important therapeutic agent. -
Stable Isotope
N-Desethyl amodiaquine-d5 dihydrochloride is a deuterium-labeled form of N-Desethyl amodiaquine dihydrochloride, the principal metabolite of Amodiaquine. This compound serves as an antiparasitic agent and exhibits significant biological activity, with IC50 values of 97 nM against V1/S strains and 25 nM against 3D7 strains. It is primarily utilized in pharmacokinetic studies and metabolic research to trace the bioavailability and metabolic pathways of antimalarial therapies. -
Stable Isotope
Benzyl benzoate-d12 is a deuterium-labeled variant of benzyl benzoate, which is a benzoic acid ester commonly used as a fragrance in cosmetic formulations. This stable isotope is valuable for research applications in studies examining scabies and inflammatory skin conditions associated with Demodex. Its use facilitates tracking and quantification in metabolic processes, enhancing understanding of相关皮肤疾病的生物学机制. -
Stable Isotope
Diethyltoluamide-d7 is a deuterated variant of Diethyltoluamide, a widely used active ingredient in insect repellents. This stable isotope serves as an analytical tool for studying the environmental fate and metabolism of Diethyltoluamide in various biological systems. Its primary applications include determining exposure levels in ecological research and enhancing the understanding of the compound's behavior in complex matrices. -
Stable Isotope
Flufenamic acid-13C6 is a stable isotope-labeled derivative of Flufenamic acid, a non-steroidal anti-inflammatory agent. It primarily targets cyclooxygenase (COX) and activates AMP-activated protein kinase (AMPK), while also modulating various ion channels, including chloride and L-type Ca2+ channels, and non-selective cation channels. Additionally, Flufenamic acid-13C6 binds to the central pocket of TEAD2 YBD, inhibiting TEAD function and impacting TEAD-YAP-dependent biological processes, such as cell migration and proliferation. This compound is valuable for metabolic studies and investigations into inflammatory pathways. -
Stable Isotope
HMMNI-d3 (Hydroxy Dimetridazole-d3) is a stable isotope labeled derivative of HMMNI (Hydroxy dimetridazole). HMMNI itself is a hydroxy metabolite of Dimetridazole, a compound belonging to the nitroimidazole class that is effective against protozoan infections. HMMNI-d3 serves as a valuable tool in biological research, enabling accurate tracking of metabolic pathways and the study of drug metabolism and pharmacokinetics. Its deuterium labeling enhances analytical sensitivity and allows for precise quantification in various experimental contexts. -
Stable Isotope
Pyrimethamine-d3 is a deuterium-labeled derivative of Pyrimethamine, primarily acting as a stable isotope. It targets dihydrofolate reductase (DHFR), thereby inhibiting the synthesis of tetrahydrofolic acid from folic acid, which is crucial for protozoal infections treatment. This compound is valuable for research applications involving metabolic studies, isotopic tracing, and pharmacokinetic assessments in the field of parasitology and microbiology. -
Stable Isotope
Methyl palmitate-d31 is a deuterated analog of methyl palmitate, functioning as a stable isotope. This compound exhibits significant acaricidal properties and has been shown to inhibit phagocytic activity and modulate immune responses. Additionally, methyl palmitate demonstrates anti-inflammatory and antifibrotic effects, making it valuable in various research applications, including studies on immune modulation and inflammation-related pathways. -
Stable Isotope
Estragole-d4 is a deuterated form of Estragole, primarily utilized as a stable isotope for labeling studies. As a volatile terpenoid ether, Estragole exhibits significant biological activities, including the induction of apoptosis and the inhibition of LPS-induced reactive oxygen species (ROS) production. It also activates the Nrf-2 pathway and regulates NF-κB signaling, contributing to its anti-inflammatory, antioxidant, and immunomodulatory properties. Estragole has been investigated for its potential effects on neuronal excitability and gastric ulcer amelioration, making it valuable in various research applications. -
Stable Isotope
Dinotefuran-d3 is a deuterium-labeled derivative of Dinotefuran, a neonicotinoid insecticide. Its primary mechanism involves the inhibition of nicotinic acetylcholine receptors, leading to disruption of the insect nervous system. This stable isotope can be utilized in research applications such as pharmacokinetic studies, environmental fate analyses, and metabolic studies of insecticides. -
Stable Isotope
Benzyl benzoate-d5 is a deuterium-labeled derivative of benzyl benzoate, serving as a stable isotope for research applications. This compound is commonly used as a fragrance ingredient and has potential in the study of scabies and inflammatory skin conditions associated with Demodex. Its isotopic labeling facilitates enhanced tracking and analysis in biological studies, contributing valuable insights into the metabolism and biological interaction of benzyl benzoate in various cosmetic and dermatological research settings. -
Stable Isotope
DL-Methionine-d4 is the deuterated form of the essential amino acid DL-Methionine, which serves as a critical component in protein synthesis and plays a role in oxidative stress defense. This stable isotope can be utilized in metabolic studies and tracer experiments to examine amino acid metabolism. Additionally, DL-Methionine has demonstrated efficacy in eliminating Heterodera rostochiensis in potato plants, highlighting its potential applications in agricultural research. -
Stable Isotope
Endoxifen-d5 is a deuterium-labeled derivative of Endoxifen, a primary active metabolite of tamoxifen. This compound exhibits enhanced affinity and specificity for estrogen receptors while also inhibiting aromatase activity. It serves as a valuable tool for breast cancer research, facilitating studies on estrogen signaling pathways and therapeutic response in hormone-receptor-positive breast cancer models. -
Stable Isotope
Methyl stearate-d35 is a deuterium-labeled variant of methyl stearate, primarily utilized as a stable isotope in research applications. Derived from sources like Rheum palmatum L., this compound serves as a key component in the formulation of biodiesels from soybean and rapeseed. Its stable isotope labeling makes it valuable for tracing studies and metabolic analysis in biochemical research. -
Stable Isotope
Flonicamid-15N18O is a stable isotope-labeled derivative of Flonicamid, which targets hemipterous pests through a distinctive mechanism of action that induces starvation by inhibiting stylet penetration into plant tissues. This novel systemic insecticide demonstrates selective activity, making it a valuable tool for studying insect feeding behavior and pest management strategies. Applications of Flonicamid-15N18O include research into insect physiology, behavioral studies, and the development of integrated pest control methods. -
Stable Isotope
Pyronaridine-d4 tetraphosphate is a deuterium-labeled derivative of the anti-malarial agent Pyronaridine tetraphosphate, targeting malaria and other parasitic infections. It exhibits potent activity against Plasmodium falciparum and Echinococcus granulosus, facilitating research into its pharmacokinetics and metabolic pathways. This stable isotope is valuable for studies in drug metabolism and efficacy in malaria research. -
Stable Isotope
Myristoleyl carnitine-d3 is a deuterium-labeled derivative of myristoleyl carnitine, serving as a stable isotope for tracer studies. This compound is valuable in the investigation of metabolic pathways involving fatty acid metabolism and energy production. Its use in scientific research enables precise measurement of metabolic processes in cellular models and can enhance understanding of cardiometabolic disorders. -
Stable Isotope
Endoxifen-d5 (Z-isomer) is the stable isotope-labeled derivative of the Z-isomer of Endoxifen. This metabolite of Tamoxifen exhibits significant anti-estrogenic activity in breast cancer cells that express the estrogen receptor alpha (ERα), contributing to its therapeutic efficacy in estrogen-sensitive tumors. Additionally, Endoxifen (Z-isomer) demonstrates a concentration-dependent inhibition of the hERG potassium channel, with an IC50 value of 1.6 μM, making it a valuable tool for research into breast cancer treatment and associated cardiotoxic effects. -
Stable Isotope
Piperonyl butoxide-d9 is a deuterium-labeled derivative of Piperonyl butoxide, a known pesticide synergist and food additive. This stable isotope is utilized in biochemical research to study metabolic pathways and enhance the understanding of Piperonyl butoxide's biological effects, which include the activation of c-Jun and ATF-2 in mouse hepatocytes. Research has indicated its potential adverse effects on reproduction, development, and behavior in model organisms, as well as its status as a carcinogen in liver studies involving rats and mice. -
Stable Isotope
Cambendazole-d7 is a deuterium-labeled derivative of Cambendazole, serving as a stable isotope. This compound is useful in studies involving pharmacokinetics and metabolic pathways, allowing for precise tracking of Cambendazole in biological systems. Its incorporation into experiments can enhance the understanding of drug action and distribute in biological matrices. -
Stable Isotope
Carbosulfan-d18 is a deuterium-labeled derivative of Carbosulfan, targeting cytochrome P450 enzymes. It exhibits potent inhibition of CYP3A4 while demonstrating moderate inhibition of CYP1A1/2 and CYP2C19 in pooled human liver microsomes. This reagent is valuable for studies exploring the metabolic activation of Carbosulfan, particularly in human liver systems. -
Stable Isotope
Proguanil-d4 is a deuterium-labeled analog of Proguanil, which serves as an antimalarial proagent. Upon administration, Proguanil is metabolized to its active form, Cycloguanil, which exerts its pharmacological effects through the inhibition of dihydrofolate reductase (DHFR). This stable isotope is utilized in research applications including pharmacokinetic studies and metabolic pathway analysis to understand drug actions and interactions.
