N-Desethyl amodiaquine-d5 dihydrochloride is a deuterium-labeled form of N-Desethyl amodiaquine dihydrochloride, the principal metabolite of Amodiaquine. This compound serves as an antiparasitic agent and exhibits significant biological activity, with IC50 values of 97 nM against V1/S strains and 25 nM against 3D7 strains. It is primarily utilized in pharmacokinetic studies and metabolic research to trace the bioavailability and metabolic pathways of antimalarial therapies.
N-Desethyl amodiaquine-d5 dihydrochloride is a deuterium-labeled form of N-Desethyl amodiaquine dihydrochloride, the principal metabolite of Amodiaquine. This compound serves as an antiparasitic agent and exhibits significant biological activity, with IC50 values of 97 nM against V1/S strains and 25 nM against 3D7 strains. It is primarily utilized in pharmacokinetic studies and metabolic research to trace the bioavailability and metabolic pathways of antimalarial therapies.
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