Oseltamivir acid-d3 is a deuterium-labeled derivative of Oseltamivir acid, which serves as the active metabolite of Oseltamivir phosphate. This compound acts as a highly selective inhibitor of influenza virus neuraminidase, exhibiting an IC50 of 2 nM against both influenza A and B viruses. While its ability to cross the blood-brain barrier is limited under normal physiological conditions, penetration is notably increased during inflammatory states, making it a valuable reagent for studying antiviral mechanisms and neuroinflammation in research applications.
Oseltamivir acid-d3 is a deuterium-labeled derivative of Oseltamivir acid, which serves as the active metabolite of Oseltamivir phosphate. This compound acts as a highly selective inhibitor of influenza virus neuraminidase, exhibiting an IC50 of 2 nM against both influenza A and B viruses. While its ability to cross the blood-brain barrier is limited under normal physiological conditions, penetration is notably increased during inflammatory states, making it a valuable reagent for studying antiviral mechanisms and neuroinflammation in research applications.
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