3-Indoleacetonitrile-d4

Catalog No.: A51927
Stable Isotope
3-Indoleacetonitrile-d4 is a deuterated derivative of 3-Indoleacetonitrile, functioning as a stable isotope. This compound exhibits significant antiviral activity, particularly against a range of influenza A viruses, HSV-1, and VSV in vitro. Notably, it reduces lung virus titers and mitigates lung lesions in vivo, while also promoting an increase in mitochondrial antiviral-signaling (MAVS) protein levels. 3-Indoleacetonitrile-d4 serves as a valuable tool in research aimed at understanding and combating viral infections, including COVID-19, HSV-1, and VSV.
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5mg
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50mg
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3-Indoleacetonitrile-d4 is a deuterated derivative of 3-Indoleacetonitrile, functioning as a stable isotope. This compound exhibits significant antiviral activity, particularly against a range of influenza A viruses, HSV-1, and VSV in vitro. Notably, it reduces lung virus titers and mitigates lung lesions in vivo, while also promoting an increase in mitochondrial antiviral-signaling (MAVS) protein levels. 3-Indoleacetonitrile-d4 serves as a valuable tool in research aimed at understanding and combating viral infections, including COVID-19, HSV-1, and VSV.
Product Information
Catalog NumA51927
FormulaC10H4D4N2
Molecular Weight160.21
CAS Number927182-31-8
SMILESN#CCC1=CNC2=C([2H])C([2H])=C([2H])C([2H])=C12
Useful Calculator

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