Edoxaban-d6 is a deuterium-labeled derivative of Edoxaban, a selective and potent inhibitor of factor Xa (FXa). Edoxaban exhibits high affinity for FXa with an IC50 of 0.561 nM, making it an effective anticoagulant for stroke prevention. It also displays weak inhibitory activity against thrombin and factor IXaβ, while maintaining a selectivity of over 10,000-fold for FXa. This reagent is useful for studying antithrombotic mechanisms and evaluating treatments for thromboembolic diseases in a variety of research applications.
Edoxaban-d6 is a deuterium-labeled derivative of Edoxaban, a selective and potent inhibitor of factor Xa (FXa). Edoxaban exhibits high affinity for FXa with an IC50 of 0.561 nM, making it an effective anticoagulant for stroke prevention. It also displays weak inhibitory activity against thrombin and factor IXaβ, while maintaining a selectivity of over 10,000-fold for FXa. This reagent is useful for studying antithrombotic mechanisms and evaluating treatments for thromboembolic diseases in a variety of research applications.
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