Apixaban-d3 is a deuterium-labeled analogue of Apixaban, a reversible and selective inhibitor of Factor Xa. With inhibition constants of 0.08 nM and 0.17 nM in human and rabbit models respectively, Apixaban demonstrates significant effectiveness in preventing thromboembolic diseases. This stable isotope is particularly useful in pharmacokinetic studies and bioanalytical research, allowing for enhanced tracking of the drug's metabolism and distribution in biological systems.
Apixaban-d3 is a deuterium-labeled analogue of Apixaban, a reversible and selective inhibitor of Factor Xa. With inhibition constants of 0.08 nM and 0.17 nM in human and rabbit models respectively, Apixaban demonstrates significant effectiveness in preventing thromboembolic diseases. This stable isotope is particularly useful in pharmacokinetic studies and bioanalytical research, allowing for enhanced tracking of the drug's metabolism and distribution in biological systems.
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