Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Lysozyme, also known as Muramidase, is a conserved antimicrobial protein that targets bacterial cell wall peptidoglycan (PG). It exerts a bactericidal effect by hydrolyzing PG, thereby limiting bacterial growth on mucosal surfaces and controlling potential pathogens while preventing dysbiosis through microbiota regulation. Additionally, extracellular lysozyme degrades polymeric PG into soluble fragments, activating NOD receptors in mucosal epithelial cells and stimulating the secretion of chemokines and activating factors by neutrophils and macrophages. This makes lysozyme a valuable reagent for studies involving antimicrobial activity, immune response, and microbiome research. -
Bacterial Inhibitor
Ciclopirox olamine is a synthetic antifungal agent primarily targeting various fungal pathogens. It exhibits a broad spectrum of activity against dermatophytes, yeasts, molds, and multiple Gram-positive and Gram-negative bacteria. In addition to its antibacterial properties, Ciclopirox olamine has demonstrated anticancer and anti-inflammatory effects, making it a valuable reagent for research in superficial mycoses, cancer biology, and inflammation studies. -
5-HT3 Antagonist
Palonosetron is a selective 5-HT3 antagonist that effectively prevents acute, delayed, and overall chemotherapy-induced nausea and vomiting. In addition to its primary application in oncology, Palonosetron demonstrates moderate activity against flaviviruses and exhibits potent antiviral effects against Zika virus in mammalian cells. Furthermore, this compound has been associated with antidepressant properties, making it a valuable tool for diverse research applications in both oncology and virology. -
5-HT3 Antagonist
Palonosetron hydrochloride is a selective 5-HT3 receptor antagonist that primarily functions to prevent acute and delayed nausea and vomiting associated with chemotherapy. Beyond its primary application, Palonosetron hydrochloride demonstrates moderate activity against flaviviruses, including potent efficacy against the Zika virus in mammalian cells. Additionally, this compound has been associated with antidepressant effects, expanding its potential therapeutic applications in neurological research. -
Antibacterial Preservative
Imidazolidinyl urea functions as an antibacterial preservative by releasing formaldehyde through its decomposition. It exhibits broad-spectrum antibacterial activity, effectively inhibiting the growth of both gram-negative and gram-positive bacteria, as well as limiting yeast and mold proliferation. Additionally, it can be utilized in the formulation of multifunctional hydrogels for managing infectious wounds. Notably, Imidazolidinyl urea may also induce non-histaminergic allergic responses via the activation of MRGPRX2 in mast cells. -
Antibacterial Agent
Ornidazole is a nitroimidazole derivative primarily used as an antibacterial agent. It demonstrates anti-trichomonad activity and is effective against a range of anaerobic bacteria in vitro. Additionally, Ornidazole inhibits the Sonic hedgehog (Shh) signaling pathway and exhibits antitumor properties, making it a valuable tool in the investigation of conditions such as Crohn’s disease. -
Bacterial Inhibitor
X-Neu5Ac sodium is a neuraminidase substrate that facilitates the chromogenic assay of neuraminidase activity in bacterial expression systems. This compound has a Km value of 0.89 mM for neuraminidase, making it an effective tool for studying neuraminidase function and inhibition. Its use in research applications provides insights into bacterial mechanisms and potential therapeutic targets for bacterial infections. -
Parasite Inhibitor
Isopimpinellin acts as a potent inhibitor of parasitic activity. Isolated from Glomerella cingulata, this orally active compound prevents DNA adduct formation and inhibits skin tumor initiation induced by 7,12-dimethylbenz[a]anthracene. Additionally, Isopimpinellin demonstrates significant anti-leishmania activity, making it a valuable reagent for studies in parasitology and cancer research. -
Antibiotic
Cefaclor monohydrate is an orally active cephalosporin antibiotic that targets penicillin-binding protein 3 (PBP3). It is effective against a variety of bacterial infections, including respiratory tract infections, bacterial bronchitis, pharyngitis, and skin infections. Additionally, Cefaclor has potential applications in research related to depression and other bacterial pathologies. -
Antibacterial Agent
Domiphen bromide is a cationic quaternary ammonium salt primarily known for its antibacterial activity. It exhibits potent inhibition of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, and various bacterial phosphatases, making it versatile for medicinal applications. Due to its antibacterial and antimalarial properties, Domiphen bromide is utilized as a preservative and disinfectant and serves as a research tool in the study of bacterial infections such as pharyngitis, thrush, and oral ulcers. -
Antibiotic
Erythromycin Ethylsuccinate is an antibiotic that primarily targets bacterial infections by inhibiting protein synthesis in susceptible microorganisms. It demonstrates an antimicrobial spectrum that is comparable to, or slightly broader than, that of penicillin, making it effective against a variety of Gram-positive and some Gram-negative bacteria. Additionally, Erythromycin Ethylsuccinate exhibits antiviral activity against HIV-1, providing a versatile option for researchers studying bacterial and viral pathogens. Its applications include exploring antimicrobial resistance and developing new therapeutic strategies. -
Antibiotic
Oxolinic acid is an antibiotic effective against both Gram-negative and Gram-positive bacteria. It is primarily utilized in research focused on acute and chronic urinary tract infections. Additionally, Oxolinic acid functions as a DNA/RNA synthesis inhibitor and acts as a dopamine uptake inhibitor, demonstrating stimulatory effects on locomotor activity in murine models. -
Antibiotic
Pefloxacin mesylate dihydrate is a broad-spectrum antibiotic that primarily inhibits DNA gyrase, disrupting DNA replication. This compound demonstrates significant antibacterial activity against both Escherichia coli and Pseudomonas aeruginosa, with MIC90 values of 0.12 mg/L and 4 mg/L, respectively, and also targets Bacteroides fragilis with an MIC90 of 16 mg/L. Additionally, Pefloxacin mesylate dihydrate exhibits anti-Plasmodium yoelii activity and can enhance UVA-induced edema and immunosuppression. Its diverse profile makes it a valuable tool for infection studies and related research applications. -
Antibiotic
Succinylsulfathiazole is a sulfonamide antibiotic that targets bacterial folate synthesis, providing localized, gut-specific antibacterial activity. This compound effectively reduces coliform counts, suppresses intestinal bacterial growth, and depletes gut folate-producing bacteria while modulating hepatic mTOR signaling. Succinylsulfathiazole is utilized in research focused on nutrient deficiency and its implications, as it induces folate deficiency and related nutritional symptoms in animal models such as rats and C57BL/6 mice. This antibiotic is valuable for understanding the mechanisms of gut flora modulation and the impact on nutritional status. -
Bacterial Inhibitor
Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic that primarily targets bacterial growth by inhibiting dihydropteroate synthase and disrupting folate synthesis. This compound exhibits significant antibacterial activity and is primarily utilized in research applications focused on understanding bacterial infections and exploring antibiotic resistance mechanisms. Suitable for studies related to dermatological conditions, it aids in exploring therapeutic strategies for diseases like dermatitis herpetiformis. -
Ansamycin Antibiotic
Rifamycin sodium is an orally active ansamycin antibiotic that inhibits DNA-dependent RNA synthesis. It demonstrates significant antibacterial activity against Mycobacterium tuberculosis and modulates hepatic bile acid metabolism. Additionally, Rifamycin sodium exhibits anti-inflammatory properties, making it valuable for studying Mycobacterium tuberculosis, Bacteroides fragilis infections, and inflammation induced by lipopolysaccharides. -
Bacterial Inhibitor
Enoxacin hydrate, a fluoroquinolone antibiotic, targets bacterial DNA gyrase and topoisomerase IV, disrupting DNA replication with IC50 values of 126 µg/ml and 26.5 µg/ml, respectively. This compound exhibits significant antibacterial activity against both gram-positive and gram-negative bacteria. Additionally, Enoxacin hydrate functions as an activator of miRNA processing, facilitating siRNA-mediated mRNA degradation and enhancing the biogenesis of endogenous miRNAs. Its unique mode of action also includes the inhibition of cancer cell growth through the enhancement of TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing. -
Antibiotic
Erythromycin thiocyanate is a macrolide antibiotic that targets bacterial protein synthesis by binding to the 50S ribosomal subunit, effectively inhibiting RNA-dependent protein synthesis through interference with transpeptidation and translocation processes. This compound exhibits broad-spectrum antimicrobial activity, making it valuable in research applications related to bacterial infections. Additionally, erythromycin thiocyanate has been shown to possess antitumor and neuroprotective properties, expanding its potential utility across various biomedical research fields. -
Bacterial Inhibitor
Chlorprothixene hydrochloride functions as an antagonist of dopamine and histamine receptors, exhibiting Kis of 18 nM for hD1, 2.96 nM for hD2, 4.56 nM for hD3, 9 nM for hD5, and 3.75 nM for hH1 receptors. This compound demonstrates significant antipsychotic activity, making it a valuable tool for research into neuropharmacology and the mechanisms underlying psychotic disorders. Its receptor modulation also indicates potential applications in the study of bacterial inhibition mechanisms, providing insights into the interplay between neurotransmitter systems and microbial pathogenesis. -
Quinolone Antibiotic
Lomefloxacin is a difluoroquinolone antibiotic that primarily targets bacterial topoisomerase II, inhibiting DNA supercoiling and replication. This compound exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria and is effective in inducing reactive oxygen species (ROS) production and apoptosis. Additionally, Lomefloxacin demonstrates promising anticancer efficacy against melanoma, making it a valuable tool for research applications involving systemic bacterial infections and skin cancer studies. -
Stable Isotope
Palonosetron-d3 hydrochloride is a deuterium-labeled derivative of Palonosetron hydrochloride, functioning primarily as a 5-HT3 receptor antagonist. It is widely utilized in research to investigate mechanisms of chemotherapy-induced nausea and vomiting and is known for its ability to prevent both acute and delayed episodes. Additionally, Palonosetron hydrochloride demonstrates moderate activity against flavivirus and potent efficacy against Zika virus in mammalian cells, contributing to its relevance in virology studies. Its potential antidepressant properties also make it a compound of interest in neuropharmacology research. -
HSV Inhibitor
Acyclovir sodium is a selective inhibitor of herpes simplex virus (HSV), exhibiting strong antiherpetic activity with IC50 values of 0.85 μM for HSV-1 and 0.86 μM for HSV-2. This compound induces cell cycle disturbances and apoptosis in infected cells. Additionally, Acyclovir sodium is utilized to prevent bacterial infections during induction therapy in acute leukemia treatments, demonstrating its versatility in research applications related to viral infections and hematological malignancies. -
Anticancer/Antifungal Agent
Schinifoline is a 4-quinolinone that primarily targets cancer cell proliferation and fungal infections. It exhibits potent anticancer activity by inducing G2/M phase arrest and promoting apoptosis in cancer cells, as well as enhancing their radiosensitivity. Additionally, Schinifoline demonstrates significant antifungal properties, making it relevant for research in cancer therapies and infections, particularly regarding lung cancer and Candida albicans. -
Antibiotic
Bafilomycin C1 is a macrolide antibiotic that functions as a specific and reversible inhibitor of vacuolar-type H+-ATPases (V-ATPases). It exhibits potent antibacterial and antifungal activity, particularly against gram-positive organisms. Additionally, Bafilomycin C1 has been shown to induce apoptosis, making it a valuable tool for research into hepatocellular carcinoma (HCC) and related cellular processes. -
Antifungal Agent
Fosravuconazole L-lysine ethanolate, a prodrug of Ravuconazole, acts as an orally bioavailable broad-spectrum antifungal agent. It demonstrates significant efficacy against various fungal infections, making it a valuable tool for research on candidiasis, onychomycosis, and parasitemia. This compound is instrumental in exploring antifungal therapies and evaluating treatment outcomes in fungal-related diseases. -
Fungicide
Kresoxim-methyl is a Strobilurin-based fungicide that primarily targets the cytochrome bc1 complex, inhibiting respiration at complex III. It demonstrates high affinity binding to yeast complex III with an apparent Kd of 0.07 μM. This compound is widely utilized in agricultural research to assess its antifungal activity and its mechanisms in pathogen resistance management. -
jRdRp Inhibitopr
Kulactone is a natural bioflavonoid that functions as an inhibitor of the RNA-dependent RNA polymerase (jRdRp). This compound demonstrates significant antifungal, antibacterial, and antiplasmodial activities, making it a valuable tool in infectious disease research. Additionally, Kulactone is noted for its inability to cross the blood-brain barrier, which may limit its central nervous system effects and enhance its application in peripheral infections. -
Fungicide
Dimethomorph is a fungicide classified as a sterol biosynthesis inhibitor. It effectively disrupts fungal cell wall formation, thereby impeding fungal growth. Additionally, Dimethomorph has been shown to inhibit androgen receptor (AR) activity in MDA-kb2 cells with an IC20 value of 0.263 µM, making it relevant for studies on hormone receptor signaling and fungal pathogenesis. -
Antifungal Agent
D75-4590 is a pyridobenzimidazole derivative that functions as a β-1,6-glucan synthesis inhibitor. This compound exhibits significant antifungal activity, making it a valuable tool for investigating fungal biology and potential therapeutic applications. Its mechanism of action may aid in the development of novel antifungal strategies and enhance understanding of cell wall biosynthesis in pathogenic fungi. -
Antifungal Agent
1-Eicosanol, a long-chain fatty alcohol, functions as an antifungal agent by inhibiting mycelial growth of pathogens such as Alternaria solani and Botrytis cinerea. Derived from natural sources including the leaves of Leea indica and produced by Bacillus velezensis ZJ1, this compound is particularly relevant for research focused on tomato early blight and gray mold. Its applications extend to understanding fungal interactions and exploring biocontrol methods in agricultural settings. -
Fungicide Agent
Faltan is a dicarboximide fungicide that primarily targets fungal pathogens to inhibit their growth. It is commonly employed in the agricultural industry for the protection of vines and various vegetable crops. Additionally, Faltan exhibits cytotoxic effects on human bronchial epithelial cells, making it a valuable compound for research in both plant protection and cellular biology applications. -
Fungicide
Isoprothiolane is a potent blast fungicide that targets fungal growth during the penetration and development phases of infecting hyphae. It exhibits antifungal and anti-inflammatory properties, making it suitable for various agricultural applications. Additionally, Isoprothiolane has been shown to modulate lipid metabolism by reducing serum phospholipid and total lipid concentrations, contributing to research in fatty liver conditions. Its versatile biological activities support its use in both plant protection and metabolic studies. -
Antibiotic
Roridin E is an antibiotic that exhibits cell-inhibiting and fungicidal properties. It is known for its efficacy in combating various fungal infections and serves as a valuable tool in antimicrobial research. Roridin E's mechanism of action, which involves disrupting cellular processes in target organisms, makes it suitable for studies aimed at understanding fungal pathogenesis and potential therapeutic interventions. -
Fungicide
Flutriafol is a triazole fungicide that inhibits the enzyme lanosterol 14α-demethylase, disrupting ergosterol biosynthesis in fungal cell membranes. It exhibits broad-spectrum antifungal activity, making it effective against various plant pathogens. Flutriafol is commonly utilized in agricultural research and crop protection studies to manage fungal diseases and enhance plant health. -
antifungal agent
Abafungin is an antifungal agent that functions by inhibiting the transmethylation at the C-24 position of the sterol side chain, a reaction catalyzed by the enzyme sterol-C-24-methyltransferase. This mechanistic action disrupts ergosterol biosynthesis, which is crucial for fungal cell membrane integrity. Abafungin is used in research to study fungal pathogenesis and to develop new antifungal therapies. -
Antifungal Agent
6-Chloro-7-deazapurine-β-D-riboside functions as an antifungal agent through its nucleoside derivative structure. It demonstrates inhibitory activity against various plant pathogenic fungi, making it a valuable tool for studies in fungal biology and plant protection. This compound may be utilized in research focused on antifungal mechanisms and the development of novel therapeutic strategies in agriculture. -
Antifungal Antibiotic Agent
Candicidin is a polyene antifungal antibiotic agent that functions by binding to ergosterol in fungal cell membranes, leading to increased permeability and cell death. It exhibits potent antifungal activity against a range of pathogenic fungi. Candicidin is primarily used in research applications focused on fungal infections and the mechanisms of antifungal resistance. -
Fungicide
Quinoxyfen is a systemic fungicide that primarily targets the growth and development of powdery mildew pathogens. It exhibits significant antifungal activity by inhibiting the biosynthesis of sterols, which are essential for fungal cell membrane integrity. Quinoxyfen is widely utilized in agricultural research for its effectiveness in controlling powdery mildew in various crops, making it an important agent in plant disease management studies. -
Antibiotic
Polyhexamethyleneguanidine hydrochloride is a cationic polymer known for its broad-spectrum antimicrobial activity. It primarily exerts its antibacterial effects by interacting with bacterial and fungal cell membranes, leading to disruption of membrane integrity. This compound is valuable in research related to disinfection, water treatment, and agricultural pesticides. -
Fungal Inhibitor
Dihydrochelerythrine is a natural compound derived from Corydalis yanhusuo, primarily functioning as a fungal inhibitor. This compound exhibits notable antifungal activity, making it a valuable reagent for research applications focused on mycology and the study of fungal infections. Its properties may contribute to the development of novel antifungal therapies. -
Fungicide
Flutolanil is a broad-spectrum fungicide that primarily targets mitochondrial Complex II, inhibiting mycelial oxygen consumption and succinate dehydrogenase activity. This compound is effective against various fungal pathogens, making it valuable for managing plant diseases. Additionally, studies indicate that prolonged exposure to Flutolanil may lead to endocrine disruption and reproductive disorders in zebrafish, highlighting its relevance in ecotoxicology research. -
Fungal Inhibitor
Cauloside A, a saponin derived from the roots of Dipsacus asper, serves as a potent fungal inhibitor. It exhibits significant antifungal activity, making it a valuable reagent for research focused on fungal pathogenesis and therapeutic interventions. Its effectiveness in combating various fungal strains positions Cauloside A as a crucial tool in the study of antifungal mechanisms and the development of new antifungal agents. -
Antifungal Agent
Isopropyl ferulate is a naturally occurring compound known for its antifungal properties. It acts by inhibiting fungal growth, making it a valuable candidate for the development of antifungal agents. Additionally, isopropyl ferulate is utilized in pharmaceutical formulations and cosmetic products due to its antioxidant activity, highlighting its versatility in various biological applications. -
Fungicide
Metalaxyl-M, also known as (R)-Metalaxyl, is a selective inhibitor of fungal RNA polymerase. It demonstrates potent fungicidal activity by disrupting the synthesis of fungal ribosomal RNA. Additionally, Metalaxyl-M is useful for inducing inflammation in hepatocytes and modulating tryptophan metabolism. Its applications extend to ecotoxicology studies, making it a valuable reagent for investigating fungal resistance and environmental impacts. -
Fungicide
Picoxystrobin is a strobilurin fungicide that targets mitochondrial respiration to control a broad spectrum of plant diseases. This compound is known for its potent activity against fungal pathogens, making it invaluable in agricultural research. Additionally, studies have shown that Picoxystrobin exhibits high toxicity in zebrafish embryos, leading to developmental abnormalities, oxidative stress, and immunotoxic effects, underscoring its relevance in ecotoxicological assessments. -
Antiplasmodial Agent
Neocryptolepine is a potent antiplasmodial agent, exhibiting significant activity against Plasmodium spp. Additionally, it demonstrates antibacterial effects, particularly against Gram-positive bacteria with a minimum inhibitory concentration (MIC) below 100 μg/mL, as well as antifungal properties. This compound serves as a valuable tool in research focused on malaria treatment and the development of novel antimicrobial therapies. -
Antifungal Agent
(+)-Columbianetin acetate functions as an antifungal agent with significant biological activity. This compound is an isomer of Columbianetin, a phytoalexin found in celery (Apium graveolens), which is linked to enhanced resistance against pathogens during storage. Research applications include the study of its antifungal and anti-inflammatory properties, making it a valuable tool for exploring plant defense mechanisms and developing new antifungal therapies. -
Fungus Metabolite
Averantin is a fungal metabolite derived from Cercospora arachidicola, serving as a precursor in the biosynthesis of aflatoxin B1. This compound is integral to the study of fungal metabolism and can be utilized to explore the biosynthetic pathways of mycotoxins. Researchers can leverage Averantin to investigate its role and impact in various biological processes related to fungal development and toxin production. -
Bacterial Inhibitor
Bafilomycin B1 is a macrolide antibiotic that targets vacuolar H+-ATPases (V-ATPases). It exhibits neuroprotective properties against Chloroquine-induced cell death and can significantly inhibit the accumulation of lipid droplets induced by oxidized low-density lipoprotein (LDL). Bafilomycin B1 is valuable for research focused on bacterial inhibition and studying lipid metabolism and cellular stress responses. -
Antineoplastic Agent
Protoneogracillin is a furostanol glycoside with demonstrated antineoplastic properties. It exhibits cytotoxic effects on K562 cancer cells with an IC50 value of 6.6 μM, indicating significant potential for cancer research. Additionally, Protoneogracillin has anti-fungal activity against the plant pathogenic fungus Pyricularia oryzae, with an MMDC of 94.0 μM, suggesting broader applications in phytopathological studies.
