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Protoneogracillin

Catalog No.: A28384
Antineoplastic Agent
Protoneogracillin is a furostanol glycoside with demonstrated antineoplastic properties. It exhibits cytotoxic effects on K562 cancer cells with an IC50 value of 6.6 μM, indicating significant potential for cancer research. Additionally, Protoneogracillin has anti-fungal activity against the plant pathogenic fungus Pyricularia oryzae, with an MMDC of 94.0 μM, suggesting broader applications in phytopathological studies.
Protoneogracillin 191334-50-6 Antineoplastic Agent
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Size Price Stock Qty
5mg
$320.00
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10mg
$525.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionProtoneogracillin is a furostanol glycoside with demonstrated antineoplastic properties. It exhibits cytotoxic effects on K562 cancer cells with an IC50 value of 6.6 μM, indicating significant potential for cancer research. Additionally, Protoneogracillin has anti-fungal activity against the plant pathogenic fungus Pyricularia oryzae, with an MMDC of 94.0 μM, suggesting broader applications in phytopathological studies.
Product Information
Catalog NumA28384
FormulaC51H84O23
Molecular Weight1065.20
CAS Number191334-50-6
SMILESC[C@@]12[C@](C[C@@]3([H])[C@]2([H])[C@@H]([C@](O)(O3)CC[C@H](C)CO[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C)([H])[C@@]5([H])[C@]([C@@]6(C(C[C@H](CC6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)=CC5)C)([H])CC1
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Microbiology > Antifection > Fungal