Catalog No.
Product Name
Application
Product Information
Citations
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Anti-Bacterial Agent
Azicemicin B is an antibacterial agent that exhibits weak antimicrobial activity. Its low toxicity profile has been demonstrated in mouse models, making it a candidate for further evaluation in microbial research and potential therapeutic applications. This compound may be useful in studies exploring the mechanisms of bacterial resistance and the development of novel antibacterial strategies. -
Anti-Bacterial Agent
Emerimicin IV is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria. It interferes with bacterial protein synthesis, making it a valuable compound for research focused on developing new antimicrobial therapies. This reagent is particularly useful in studies investigating bacterial resistance and the mechanisms of action of antibiotics. -
Anti-Bacterial Agent
Lactonamycin is an anti-bacterial agent known for its potent activity against Gram-positive bacteria, specifically Staphylococcus, Streptococcus, Enterococcus, MRSA, and VRE, with minimum inhibitory concentrations (MIC) ranging from 0.39 to 0.78 μg/mL. Additionally, Lactonamycin demonstrates cytotoxic effects on various tumor cell lines, including L-1210, P388, S180, FS-3, Ehrlich, and B16-BL5, exhibiting IC50 values between 0.06 and 3.3 μg/mL. This compound is valuable for research focused on bacterial resistance and cancer therapeutics. -
Anti-Bacterial Agent
Nocathiacin II is a potent anti-bacterial agent primarily effective against Gram-positive bacteria. It demonstrates significant resistance to strains such as methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP), and multidrug-resistant Enterococcus faecalis (MREF). This compound is ideal for research applications focused on combating antibiotic resistance and developing effective antibacterial therapies. -
Bacterial Inhibitor
Strinoline is a bacterial inhibitor that targets and disrupts bacterial cell function. This compound exhibits significant antibacterial activity, making it a valuable tool for research in the field of microbiology. Strinoline can be utilized to study bacterial resistance mechanisms and the efficacy of antibiotic therapies. -
Antibiotic
Trinactin is a macrotetrolide antibiotic that displays potent antibacterial activity through the disruption of bacterial cell membranes. Additionally, it functions as a cation carrier, facilitating ion transport across cellular membranes. This compound is significant for research applications focused on antibiotic development, cellular ion exchange mechanisms, and studying the effects of ionophore activity in various biological systems. -
Anti-Bacterial Agent
Enaminomycin C is an anti-bacterial agent with a demonstrated ability to inhibit the growth of Gram-positive bacteria. Its activity profile shows weak effectiveness against Gram-negative bacteria, making it a candidate for further investigation in antibacterial research. Studies involving Enaminomycin C may contribute to the development of new therapeutic strategies against bacterial infections. -
Antibacterial Agent
Tacapenem, the active metabolite of CS-834, functions as a potent antibacterial agent. It demonstrates a broad spectrum of antibacterial activity against both gram-positive and gram-negative aerobes and anaerobes. Notably, Tacapenem exhibits strong bactericidal effects against Staphylococcus aureus and Escherichia coli, making it a valuable tool for research in bacterial infections and antibiotic resistance studies. -
Antibacterial Agent
Antibacterial agent 170 (compound 6b) is a potent antibacterial compound that targets the inhibition of biofilm formation in Pseudomonas aeruginosa PAO1. It demonstrates significant activity as a quorum sensing inhibitor through the las system, effectively disrupting bacterial communication and biofilm development. This agent is valuable for studies focused on microbial resistance and the mechanisms underlying bacterial pathogenicity. -
Antibacterial Agent
Colupulone is a β-acid resin derived from hops (Humulus lupulus) known for its antibacterial properties. It demonstrates significant activity against a range of bacteria as well as anti-larval effects on Culex mosquitoes. This compound is useful for investigations into infectious diseases and the development of novel antibacterial agents. -
Anti-Bacterial Agent
Kerriamycin C is an anti-bacterial agent targeting Gram-positive bacteria. It exhibits significant antibacterial activity, making it valuable for research in infectious disease and antimicrobial resistance. Additionally, Kerriamycin C has shown the ability to inhibit ascites cancer in experimental models, suggesting potential applications in cancer research. -
Antibacterial Agent
Anti-MRSA Agent 37 is an antibacterial agent specifically targeting methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) of 0.25-0.5 μg/mL. This compound effectively inhibits biofilm formation, disrupts cell wall integrity, compromises cell membrane stability, and induces oxidative stress in bacterial cells. It holds potential for research applications related to MRSA-associated diseases, particularly skin infections. -
Antibiotic
2'''-Hydroxychlorothricin is an antibiotic derived from the chlorothricin group, primarily targeting bacterial infections. Isolated from Streptomyces sp. K818, it exhibits anti-tumor properties and has been shown to extend the survival of ICR mice inoculated with Ehrlich cancer cells. This compound serves as a valuable tool in cancer research and microbiological studies focusing on antibiotic efficacy and tumor treatment. -
Bacterial Metabolite
Steffimycin B is an anthracycline bacterial metabolite derived from Streptomyces, possessing a primary mechanism of DNA binding through preferential intercalation at cytosine and guanine-rich regions. It exhibits significant cytotoxicity against various cell lines, including MCF-7, KB, NCI-H187, and Vero cells, with IC50 values of 3.5, 6.75, 3.28, and 10.5 μM, respectively. Furthermore, Steffimycin B demonstrates potent antimicrobial activity against Mycobacterium tuberculosis (MIC=5.2 nM), Bacillus cereus (MIC=1.56 μg/mL), and Plasmodium falciparum (IC50=2.19 μM), making it a valuable compound for research in cancer and infectious diseases. -
Anti-Bacterial Agent
Lunatoic acid B is an anti-bacterial agent that exhibits significant bacterial inhibitory activity. Additionally, it demonstrates partial anti-mould properties, making it useful in studies exploring microbial resistance and infection control. This compound is applicable in various research contexts, including the development of novel antibacterial formulations and understanding mechanisms of microbial growth inhibition. -
Anti-Bacterial Agent
Juvenimicin A2 is an antibacterial agent that primarily targets a range of bacteria. It has demonstrated efficacy against Gram-positive bacteria and select strains of Gram-negative bacteria. This compound is utilized in research applications aimed at understanding bacterial resistance mechanisms and developing new antimicrobial therapies. -
Antibacterial Agent
Axinysone B functions as a potent antibacterial agent, isolated from the marine alga Laurencia similis. It exhibits significant activity against Staphylococcus species, making it a valuable compound for studies focused on antibacterial properties and microbial resistance. This reagent is suitable for research applications aimed at understanding bacterial infections and exploring novel antibacterial treatments. -
Antibacterial Agent
Arizonin B2 is a microbial metabolite that functions as an antibacterial agent, primarily targeting Gram-positive bacteria. Its effectiveness against these pathogens makes it a valuable tool for research into antibacterial treatments and mechanisms of resistance. A potential candidate for studies involving the development of new antibiotics, Arizonin B2 contributes to the understanding of microbial interactions and infections. -
Antibacterial Peptoid
CHIR-29498 is an antibacterial peptoid that exhibits activity against both Gram-positive and Gram-negative bacteria. This compound is particularly useful in the investigation of pathogenic strains such as Staphylococcus aureus. CHIR-29498 serves as a valuable tool for research focused on bacterial infections and the development of novel antimicrobial therapies. -
Anti-Bacterial Agent
Olivomycin A is an antibiotic with potent activity against Gram-positive bacteria, demonstrating significant effectiveness in inhibiting bacterial growth. Its mechanism of action involves interference with nucleic acid synthesis, making it a valuable tool in microbiological research. Olivomycin A is particularly useful for studying bacterial resistance mechanisms and the development of new antimicrobial therapies. -
Antifungal Agents
Bensuldazic acid is a lipophilic 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione (THTT) derivative functioning as an antifungal agent. It exhibits significant antifungal activity, making it a valuable compound for research in fungal infections. Bensuldazic acid can also serve as a prodrug model, facilitating studies in drug development and fungal pathogenesis. -
Anti-Bacterial Agent
Rhodomycin B is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits significant antibacterial activity while demonstrating a weaker effect against Gram-negative bacteria and fungi. Rhodomycin B serves as a valuable reagent in research focusing on bacterial infections and antibiotic resistance mechanisms. -
Antimicrobial Agent
9,12,13-Trihydroxy-10-octadecenoic acid acts primarily as an antimicrobial agent. This compound exhibits significant antibacterial and antifungal properties, making it valuable for various biological research applications. It is particularly useful in studies focused on infection control and the development of novel antimicrobial therapies. -
Anti-Bacterial Agent
Midecamycin A4 is a macrolide antibiotic primarily targeting Gram-positive bacteria, exhibiting potent antibacterial activity. It demonstrates limited effectiveness against Gram-negative bacteria, mycobacteria, and fungi. This compound is valuable in research focused on antibiotic resistance and the development of novel antimicrobial agents. -
Anti-Bacterial Agent
Formadicin B is an anti-bacterial agent that exhibits potent activity against various strains of Pseudomonas, Proteobacteria, and alkaline-producing bacilli. This compound is valuable in research focused on bacterial infections and the development of new antimicrobial therapies. Its efficacy against multi-drug resistant bacteria makes it a significant candidate for further investigation in the field of microbiology. -
Antibacterial Agent
Broquinaldol is a brominated quinoline that serves as a potent antibacterial agent specifically effective against Staphylococcus species. In addition to its antimicrobial properties, Broquinaldol acts as a Mn(II) ionophore, facilitating the synthesis of metalloantibiotics. This compound is valuable in research focused on developing novel antibacterial therapies and understanding metal ion interactions in biological systems. -
Antibacterial Agent
Trospectomycin is a broad-spectrum antibacterial agent that targets bacterial protein synthesis by inhibiting ribosomal function. This compound is especially relevant in the study of resistant bacterial strains and can be utilized in research focusing on antibiotic efficacy and mechanisms of resistance. Its structural similarity to Spectinomycin allows for exploration of its unique pharmacological properties and potential therapeutic applications in infectious disease research. -
Anti-Bacterial Agent
3-Ethyl-1,3-dihydro-3-methoxy-2H-indol-2-one targets bacterial pathogens with demonstrated antimicrobial activity against both Gram-positive and Gram-negative bacteria. This indole derivative is valuable for research focused on the development of new antibacterial agents and exploring mechanisms of bacterial resistance. Its broad-spectrum properties make it a significant candidate for further investigation in microbial studies. -
Bacterial
Dealanylalahopcin is an antimicrobial agent primarily targeting bacterial pathogens. Isolated from Streptomyces leucoderma subsp. ochraceus, this compound demonstrates weak antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it exhibits moderate inhibition of collagen prolyl hydroxylase, making it a potential candidate for studies in collagen-related research and antimicrobial applications. -
Antibacterial Agent
SC 44914 is a quinoxaline derivative primarily known for its antibacterial properties. It exhibits significant activity against a range of pathogenic bacteria, including Campylobacter jejuni, Campylobacter coli, and Clostridium difficile. This compound is valuable for research applications focused on antibiotic development and the study of bacterial resistance mechanisms. -
Anti-Bacterial Agent
Isohematinic acid is a compound with established activity as an anti-bacterial agent. It exhibits weak inhibition against anaerobic bacteria, making it a valuable tool for researching microbial infections. Its functionality supports studies focused on understanding bacterial resistance mechanisms and developing novel therapeutic strategies. -
Bacterial Metabolite
Neoaureothin is a bacterial metabolite derived from Streptomyces that functions as an androgen receptor (AR) antagonist. It effectively inhibits the binding of dihydrotestosterone (DHT) to ARs, demonstrating an IC50 of 13 μM, and significantly reduces DHT-induced prostate-specific antigen expression in LNCaP cells with an IC50 of 1.75 nM. Additionally, Neoaureothin exhibits cytotoxic effects on A549, HCT116, and HepG2 cell lines with IC50 values of 34.3, 47, and 37.2 μg/mL, respectively. It also displays potent nematocidal activity against B. xylophilus, with an LC50 of 0.84 μg/mL, and enhances the survival of P. densiflora trees infected with this nematode. -
Antibacterial Agent
A-867191 hydrochloride is a selective inhibitor of DNA gyrase, acting primarily as an antibacterial agent. This compound exhibits potent antibacterial activity, making it a valuable tool in the study of bacterial infections. A-867191 hydrochloride is suitable for various research applications focused on combating antibiotic resistance and understanding bacterial DNA replication mechanisms. -
Anti-Bacterial Agent
Cissetin is an anti-bacterial agent that selectively targets Gram-positive bacteria, demonstrating significant activity against various drug-resistant strains. This compound is valuable for research applications focused on exploring mechanisms of antibiotic resistance and developing novel antibacterial therapies. Its efficacy against resistant pathogens makes it an important candidate for further study in infectious disease research. -
Antibacterial Agent
Antibacterial agent 327 is a potent inhibitor of Staphylococcus aureus DNA gyrase, demonstrating an IC50 of 0.28 μM against supercoiling activity. It additionally inhibits ATPase activities of both DNA gyrase and Topoisomerase IV, with IC50 values of 0.43 μM and 0.73 μM, respectively, while also affecting Topoisomerase IV decatenation activity (IC50: 2.31 μM). This compound effectively inhibits Clostridioides difficile and methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 0.78 μg/mL for both, and shows an MIC50 of 0.78 μg/mL against Escherichia coli. Antibacterial agent 327 is valuable for research focused on bacterial resistance and DNA topology. -
Antibacterial Agent
2,2',4'-Trichloroacetophenone functions as an antibacterial agent targeting various bacterial pathogens. It demonstrates significant antibacterial activity against Xanthomonas oryzae pv. oryzae and Xanthomonas axonopodis pv. citri, with effective concentrations (EC50) of 0.54 mg/L and 2.02 mg/L, respectively. This compound is suitable for research applications focused on understanding antibacterial properties and mechanisms. -
Anti-Bacterial Agent
Chloronectrin functions as an anti-bacterial agent with a primary mechanism targeting Gram-positive bacteria. It exhibits significant inhibitory activity against various strains, making it valuable for research in antibacterial efficacy and the development of new therapeutic agents. This compound is particularly useful for studies focused on combating Gram-positive bacterial infections. -
Antibacterial Agent
10-Methyldodec-2-en-4-olide is an antibacterial agent derived from Streptomyces. It exhibits significant antibacterial activity against a range of pathogens, including Botrytis cinerea, Saccharomyces cerevisiae, Staphylococcus aureus, and Micrococcus luteus. This compound may be useful in various research applications exploring antimicrobial efficacy and mechanisms of resistance. -
Anti-Bacterial Agent
4-Deoxybostrycin is a potent anti-bacterial agent targeting Bacillus subtilis. This compound exhibits significant antibacterial activity, making it a valuable tool for studying bacterial infections and developing new antimicrobial therapies. Its efficacy against Gram-positive bacteria highlights its potential applications in microbiological research and drug discovery. -
Anti-Bacterial Agent
Saframycin D is an anti-bacterial agent that exhibits effective activity against Gram-positive bacteria. Additionally, it shows limited activity against mycobacteria. This compound is valuable for research applications focused on bacterial infections and the study of bacterial resistance mechanisms. -
Bacterial Agonist
Rhizopterin is a bacterial agonist that plays a critical role in promoting plant growth by facilitating the synthesis of rhizobactin in folate-deficient synthetic media. Its unique mechanism enhances nutrient availability and supports the growth of beneficial rhizobacteria. This reagent is valuable for research applications in microbiology, plant biology, and the study of plant-microbe interactions. -
Antibacterial Agent
Antibacterial Agent 152 is an antibacterial compound targeting Mycobacterium smegmatis MC2-155. It demonstrates moderate antibacterial activity, with a minimum inhibitory concentration (MIC) ranging from 8 to 16 μg/mL. This reagent is useful for research applications focused on combating mycobacterial infections and studying antimicrobial resistance mechanisms. -
Anti-Bacterial Agent
Bagougeramine A is an anti-bacterial agent derived from the Bacillus circulans strain TB-2125. It exhibits significant activity against both Gram-positive and Gram-negative bacteria, making it a valuable compound for antibacterial research. This reagent can be utilized in studies focused on microbial resistance, pathogen interaction, and the development of novel antibacterial therapeutics. -
Anti-Bacterial Agent
Hazimycin 6 is an anti-bacterial agent that demonstrates moderate activity against Gram-negative bacteria, as well as yeast and dermatophytes. Its broad-spectrum capabilities make it a valuable reagent for studies in infectious disease research and antimicrobial efficacy evaluations. Researchers can utilize Hazimycin 6 to explore mechanisms of action and resistance in targeted microbial species. -
Antibacterial Agent
IMBI is an antibacterial agent that functions by inhibiting quorum sensing (QS), effectively targeting drug-resistant pathogens. This compound exhibits the ability to impede biofilm formation in Salmonella marcescens, enhancing its susceptibility to antimicrobial drugs. IMBI is valuable for research focused on combating antimicrobial resistance and understanding bacterial communication mechanisms. -
Antibacterial Agent
8-Desmethoxy-8-fluoro Moxifloxacin is an antibacterial agent that primarily targets bacterial DNA gyrase and topoisomerase IV, leading to bactericidal activity. It demonstrates effectiveness against a range of pathogens, including Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis. This compound is useful in research focused on antibacterial drug development and resistance mechanisms. -
Antibacterial agent
Antibacterial agent 223 (compound D8-03) targets Francisella tularensis by inhibiting its intracellular growth. This compound demonstrates significant antibacterial activity in preclinical models, making it a valuable tool for research on tularemia and related infections. Antibacterial agent 223 is useful for studying pathogen-host interactions and evaluating potential therapeutic strategies against intracellular pathogens. -
Anti-Bacterial Agent
Cyathin A4 functions as an anti-bacterial agent, exhibiting weak activity against Gram-positive and Gram-negative bacteria, actinomycetes, and dermatophytes. Additionally, this compound demonstrates an anti-ischemic effect, improving cerebral ischemia in a rat model. Its unique biological properties make it a valuable tool for research in microbiology and neuroprotection studies. -
Antifungal Agents
Bensuldazic acid sodium is a sodium salt of a 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione (THTT) derivative known for its lipophilic properties. It exhibits significant antifungal activity, functioning effectively as a prodrug model in various studies. This compound is utilized in research focused on antifungal agents and can aid in the development of novel therapeutic strategies against fungal infections. -
Anti-Bacterial Agent
Pyrronamycin B is an antibacterial agent with demonstrated efficacy against a range of Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Enterococcus, Escherichia coli, Klebsiella pneumoniae, Proteus, Shigella, and Salmonella. In addition to its antibacterial properties, Pyrronamycin B exhibits anti-tumor activity, making it a valuable compound for research in both infectious disease and cancer biology.
