Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Actinobolin hemisulfate is an antibiotic that primarily inhibits protein synthesis by targeting both bacterial and eukaryotic ribosomes. This compound demonstrates significant antibacterial activity against Mycobacterium smegmatis and Escherichia coli, with IC50 values of 19.2 μmol/L and 27.9 μmol/L, respectively. Additionally, it acts on rabbit reticulocyte lysate with an IC50 of 288 μmol/L. Actinobolin hemisulfate is valuable for research applications focusing on bacterial resistance and protein synthesis inhibition mechanisms. -
Antitumor Antibiotic
Lactoquinomycin B is an antitumor antibiotic that exerts its effects by targeting and inhibiting various cancer cell lines. It demonstrates significant activity against Gram-positive bacteria and exhibits weak effects on some Gram-negative bacteria, though it is ineffective against fungi. In cell viability assays, Lactoquinomycin B inhibits lymphoma L5178Y progenitor cells, as well as Adriamycin-resistant and Bleomycin-resistant cell lines, with observed ID50 values of 0.43, 0.21, and 0.19 μg/mL, respectively, indicating its potential utility in cancer research and antibiotic susceptibility studies. -
Antibiotic
Elmycin D is an antibiotic derived from Streptomyces cellulosae ssp. griseoincarnatus. It functions by inhibiting bacterial growth, making it a valuable tool in research aimed at studying antimicrobial properties and identifying potential therapeutic agents. This compound is primarily utilized in investigations related to antibiotic resistance and microbial pathogenicity. -
Antibiotic
2-Hydroxygentamicin C1 is a potent antibiotic belonging to the gentamicin class, targeting both Gram-positive and Gram-negative bacteria. It exhibits significant antibacterial activity, making it suitable for research applications focused on studying bacterial resistance and antibiotic efficacy. This compound is essential for exploring mechanisms of action and therapeutic potential in infectious disease research. -
Antibiotic
Milbemycin α13 is an antibiotic that exerts its effects by targeting neuronal signaling pathways in nematodes and arthropods. This compound is effective in killing various nematodes and mites, making it valuable for research related to parasitology and pest management. Its mechanism of action offers insights into neurobiology and potential therapeutic strategies against parasitic infections. -
Antitumor Antibiotic
Lactonamycin Z is an antitumor antibiotic that exerts its effects primarily through selective inhibition of tumor cell growth. It demonstrates significant cytotoxic activity against human cancer cell lines, including HMO2, MCF7, and Hep G2, with GI50 values of 1.9 μg/mL, 0.85 μg/mL, and 5.11 μg/mL, respectively. While it exhibits weak anti-Gram-positive bacterial activity, its primary research applications lie in the exploration of tumor cell mechanisms and potential therapeutic interventions in cancer treatment. -
Antibiotic
Liriodenine methiodide is an antibiotic with notable activity against Candida albicans and Saccharomyces cerevisiae. This compound exhibits antimicrobial properties, making it a valuable reagent for research on fungal infections and related mechanisms. Its application extends to studies focused on antibiotic efficacy and resistance patterns in pathogenic yeast. -
Antibiotic
5-Hydroxymethylblasticidin S is a broad-spectrum antibiotic that targets bacterial ribosomes, disrupting protein synthesis. Derived from Streptomyces setonii, it exhibits potent antimicrobial activity against a variety of Gram-positive and Gram-negative bacteria. This compound is valuable for research applications focused on antibiotic resistance, microbial growth inhibition, and the study of bacterial ribosome function. -
Antitumor Antibiotic
Prothracarcin is an antitumor antibiotic that exerts its cytotoxic effect by covalently binding to the C-2 amino group of guanine residues in the minor groove of DNA, leading to disruption of DNA function and ultimately cell death. In addition to its antitumor properties, Prothracarcin also demonstrates antibacterial activity against select Gram-positive and certain Gram-negative bacteria, including Escherichia coli. This dual functionality makes Prothracarcin a valuable reagent in cancer research and studies involving bacterial infections. -
Antibiotic
Milbemycin β3 is a macrolide antibiotic that targets insect neural mechanisms. It exhibits potent insecticidal activity, effectively controlling harmful agricultural pests, including larvae and other insects. This compound is widely utilized in research applications focused on pest management and agricultural studies. -
Antibiotic
Argimicin C is an antibiotic derived from Sphingomonas sp. This compound demonstrates significant algicidal activity against various toxic cyanobacteria, exhibiting minimal inhibitory concentrations (MIC) in the low micromolar range. Argimicin C is valuable for research applications focused on algal blooms and the management of harmful cyanobacterial populations. -
Antibiotic
Desmycosin is a macrolide antibiotic known for its potent antibacterial properties. It demonstrates significant activity against Haemophilus influenzae, Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes, with minimum inhibitory concentration (MIC) values of 4, 1, <0.125, and <0.125 µg/ml, respectively. As an acidic degradation product of tylosin, desmycosin serves as a valuable tool in microbiological research and therapeutic applications targeting these bacterial pathogens. -
Antibiotic
Erythromycin propionate, a derivative of the macrolide antibiotic erythromycin, primarily targets bacterial protein synthesis. This compound exhibits broad-spectrum antibacterial activity, making it suitable for treating various bacterial infections. However, it is important to note that erythromycin propionate can induce liver toxicity, particularly cholestatic hepatitis, due to its interference with bile acid transport. This compound is valuable in research related to antibiotic efficacy and liver safety assessments. -
Antibiotic
Ophiobolin D is a terpenoid antibiotic targeting various microbial pathogens. It exhibits notable biological activity against Gram-positive bacteria, mycobacteria, and fungi, with a specific focus on inhibiting certain plant pathogens. While it demonstrates a weaker inhibitory effect on Staphylococcus aureus, Ophiobolin D is valuable for research applications related to antibiotic development and understanding microbial resistance mechanisms. -
Fluoroquinolone Antibiotic
Tosufloxacin hydrate is an orally active fluoroquinolone antibiotic that primarily targets bacterial DNA gyrase and topoisomerase IV. It exhibits a broad spectrum of antibacterial activity against both gram-positive and gram-negative bacteria. This compound is utilized in research applications to study bacterial resistance mechanisms and the efficacy of fluoroquinolone antibiotics in treating infections. -
Antibiotic
Pluracidomycin A2 is a carbapenem antibiotic targeting bacterial cell wall synthesis. It exhibits potent antimicrobial activity against both Gram-positive and Gram-negative bacteria, making it a valuable compound for research in antibiotic resistance and bacterial infections. Its unique mechanism of action positions it as a promising candidate for further development in therapeutic applications. -
Antibiotic
Metronidazole phosphate disodium is a water-soluble prodrug of Metronidazole, primarily acting as an antibiotic. This compound is effective against anaerobic infections, making it a valuable reagent for studying bacterial resistance mechanisms and developing therapies for infectious diseases. Its parenteral formulation enables research applications in pharmacokinetics and drug delivery systems. -
Antibiotic
A-269A is an antibiotic compound derived from Streptomyces sp., exhibiting notable antimicrobial activity. It works by inhibiting protein synthesis, making it effective against a range of bacterial strains. This compound is valuable for research applications in microbiology and antibiotic susceptibility testing. -
Antibiotic
Chrymutasin A is a glycosidic antibiotic with notable antitumor properties. It exhibits cytotoxic activity against various cancer cell lines, making it a valuable tool in cancer research. This compound is particularly useful for studying mechanisms of action related to antibiotic resistance and tumor cell survival. -
Antibiotic
Nodusmicin is a macrolide antibiotic that exhibits activity against both antibiotic-susceptible and antibiotic-resistant strains of Staphylococcus aureus. It demonstrates minimal inhibitory concentration (MIC) values of 125 μg/mL for the UC-76 strain, and 250 μg/mL for both UC-6685 and UC-6690 strains. This compound is significant for research applications involving the mechanisms of antibiotic resistance and the development of new therapeutic strategies against bacterial infections. -
Antitumor Antibiotic
16-Hydroxyroridin L-2 is a trichothecene group antibiotic that exhibits significant antitumor activity. As a mycotoxin, it has been shown to inhibit the growth of various cancer cell lines, making it a valuable reagent for cancer research. This compound is useful for studies focusing on the mechanisms of tumor suppression and the exploration of potential therapeutic strategies against malignancies. -
Antibiotic
Sannamycin K is an aminoglycoside antibiotic that primarily targets bacterial protein synthesis. It exhibits weak antibacterial activity against both Gram-positive and Gram-negative bacteria. This compound is suitable for research applications focused on studying antibiotic mechanisms and bacterial resistance. -
Antibiotic
(E)-Cefodizime is an antibiotic that primarily targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall synthesis. This mechanism of action allows it to exert significant antibacterial activity against a range of bacterial pathogens. (E)-Cefodizime is particularly relevant for research into bacterial infectious diseases and is valuable in studies focusing on preoperative infection prophylaxis. -
Antibiotic
AR-709 is a diaminopyrimidine antibiotic that targets bacterial pathogens. It demonstrates strong antibacterial activity against Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) of 0.03 mg/L. AR-709 is suitable for research applications focused on understanding and combating bacterial infections. -
Antibiotic
Ritipenem is a penicillin antibiotic that targets penicillin-binding proteins with high affinity, demonstrating an IC50 in the ng/mL range. It exhibits significant antibacterial activity, particularly against Haemophilus influenzae, highlighting its potential use in treating bacterial infections. This compound is valuable for research applications focused on antibiotic efficacy and mechanisms of resistance. -
Antibiotic
Amythiamicin A is a potent antibiotic that primarily targets Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Additionally, it exhibits antimicrobial activity against the malaria parasite Plasmodium falciparum. This compound is valuable for research applications focused on combating resistant bacterial infections and understanding parasitic diseases. -
Antibiotic
Corynecin I is an antibiotic derived from Corynebacterium hydrocarboclastus, exhibiting potent antimicrobial activity. It is primarily effective against Gram-positive bacteria and plays a critical role in research related to antibiotic development and resistance mechanisms. Additionally, its precursor, D-(-) threo-p-amino phenyl serinol-N-acetylamine, demonstrates a minimal inhibitory effect on Corynecin synthesis from mevalonic acid, providing insights into its biosynthetic pathway. -
Antibiotic
Fluvirucin B4 is an antibiotic with activity against the influenza A virus. This compound demonstrates antiviral properties, making it useful in research related to influenza infections and the development of antiviral therapies. Its mechanism of action involves inhibition of viral replication, contributing to its effectiveness in combating influenza A virus. -
Antibiotic
Gilvocarcin M is an antibiotic derived from the bacterium S. gilvotanareus, exhibiting significant activity against Staphylococcus aureus with a minimum inhibitory concentration of 32 µg/ml. Additionally, it demonstrates potent antitumor effects on KB cells, showing an IC50 of 0.52 µg/ml. Its mechanism of action includes intercalation into bacteriophage PM2 DNA, making it a valuable tool for research in infectious diseases and cancer biology. -
Antibiotic
Arylomycin A1 is a lipohexapeptide antibiotic that targets Gram-positive bacteria. It exhibits potent antibacterial activity by inhibiting the function of bacterial signal peptidases. This compound is valuable for research into antibiotic mechanisms and the development of new therapeutic agents targeting resistant bacterial strains. -
Bacterial Inhibitor
Norfloxacin hydrochloride is a broad-spectrum antibacterial agent that targets and inhibits DNA gyrase, thus interfering with bacterial DNA replication and repair. It exhibits activity against a wide range of Gram-positive and Gram-negative bacteria, making it a valuable reagent for microbiological research and the study of bacterial resistance mechanisms. This compound is utilized in the investigation of bacterial infections and the development of new antimicrobial therapies. -
Antibiotic
MM 47755 (8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin) is a potent antibiotic derived from the actinobacterium Streptomyces. It exhibits significant antibacterial activity, making it a valuable compound for microbiological studies. Research applications include the investigation of bacterial resistance mechanisms and the development of new antimicrobial therapies. -
Antibiotic
Clavariopsin B is a cyclic depsipeptide antibiotic that exerts antifungal activity. It demonstrates significant efficacy against Candida albicans strains IFO 0583 and ATCC 10231, as well as Aspergillus niger and Aspergillus fumigatus, with minimum inhibitory concentration (MIC) values ranging from 4 to 16 μg/mL. This compound is useful in research applications focusing on fungal infections and the development of new antifungal therapies. -
Antibacterial Agent
Antibacterial Agent 285 is a cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits potent antibacterial activity against gram-negative bacteria, with minimum inhibitory concentrations (MICs) of 0.125-0.5 µg/mL for carbapenem-resistant Acinetobacter baumannii, 0.125-0.5 µg/mL for Klebsiella pneumoniae, and 0.125-2 µg/mL for Pseudomonas aeruginosa. This compound is suitable for research applications related to bacterial infections, including complicated urinary tract infections and kidney infections. -
Antibiotic
Paldimycin A is an antibiotic derived from Streptomyces paulus, primarily targeting Gram-positive bacteria. This compound disrupts bacterial protein synthesis and alters cell membrane function, leading to its antibacterial activity. Paldimycin A is valuable for research applications focusing on bacterial resistance and the mechanisms of antibiotic action. -
Antibiotic
Amicoumacin A is an orally active antibiotic that targets bacterial ribosomes, inhibiting translation by stabilizing the interaction between mRNA and ribosomes. This compound exhibits potent antibacterial activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, as well as pathogens such as Salmonella, Shigella, and Helicobacter pylori. Additionally, Amicoumacin A has demonstrated anti-inflammatory and anti-ulcer properties, making it suitable for research in lung and breast cancer, bacterial infections, inflammatory edema, and gastric ulcer studies. -
Antibiotic
2-Hydroxygentamicin B1 is a 3-aminoglycoside antibiotic that targets bacterial protein synthesis by inhibiting the 30S ribosomal subunit. It exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria. This compound is primarily used in research applications focusing on antibiotic resistance and the mechanisms of bacterial infections. -
Antibiotic
Arylomycin B6 is a lipohexapeptide antibiotic that targets Gram-positive bacteria. It exhibits potent antimicrobial activity, making it a valuable reagent for research focusing on bacterial infection mechanisms and resistance. This compound serves as a critical tool in the development of novel antibacterial therapies and contributes to the understanding of peptide antibiotics in microbiology. -
Antitumor Antibiotic
1-Hydroxyauramycin A is an anthracycline antibiotic that primarily targets tumor cells. It exhibits significant antitumor activity and is also effective against Gram-positive bacteria. This compound is utilized in research for its potential applications in cancer therapy, as well as in studies related to bacterial resistance. -
Antitumor Antibiotic
Glidobactin B is an antitumor antibiotic that exhibits potent activity against pathogenic fungi and yeast. This compound has been shown to enhance survival rates in mice inoculated with leukemia P388 cells, making it a valuable tool for research in cancer therapeutics and infectious disease. Its unique properties enable the exploration of potential treatments for various malignancies and fungal infections. -
Antibiotic
Chitinovorin A is a β-lactam antibiotic that exhibits selective antibacterial activity. Although it demonstrates weak inhibitory effects against Gram-negative bacteria, it may possess unique properties that warrant further exploration. This compound is suitable for research applications in studying antibiotic mechanisms and resistance patterns in microbial populations. -
Antibiotic
Actinoidin A is a glycopeptide antibiotic primarily targeting Gram-positive bacteria. It exhibits potent antimicrobial activity, making it a valuable tool in studies focused on bacterial resistance and antibiotic efficacy. Actinoidin A is applicable in research involving the development of new therapeutic strategies against Gram-positive infections. -
Antibiotic
Clavariopsin A is a cyclic depsipeptide antibiotic that exhibits potent antifungal activity against various strains of Candida and Aspergillus species. Specifically, it demonstrates minimum inhibitory concentrations (MIC) of 8 μg/mL for Candida albicans IFO 0583 and ATCC 10231, as well as 16 μg/mL against Aspergillus niger, 2 μg/mL for Aspergillus fumigatus AJ117190, and 4 μg/mL for Aspergillus fumigatus JCM1739. Clavariopsin A serves as a valuable tool for research focusing on fungal infections and antibiotic development. -
Antibacteriophage Antibiotic
RK-1441A is a pyrrolobenzodiazepine antibiotic that demonstrates potent antibacteriophage activity. This compound is utilized in research applications focusing on viral infections in bacterial systems. Its mechanism of action makes it a valuable tool for studying phage biology and the interactions between bacteriophages and their bacterial hosts. -
Antitumor Antibiotic
Memnobotrin B is an antitumor antibiotic derived from Memnoniella echinata (JS6308). It demonstrates significant inhibitory effects on various cancer cell lines, including NCI-460, MCF7, and SF-268. This compound is valuable for research applications focused on evaluating its cytotoxicity and potential therapeutic effects in cancer studies. -
Antibiotic
31-Homorifamycin W is an antibiotic that targets bacterial ribosomes, disrupting protein synthesis. Isolated from Amycolatopsis mediterranei, it demonstrates significant antibacterial activity against various gram-positive bacteria. Research applications include studying mechanisms of antibiotic resistance and exploring novel therapeutic strategies for bacterial infections. -
Antibiotic
Sarubicin B is a quinone antibiotic that targets Gram-positive bacteria, exhibiting potent antibacterial activity. Isolated from the culture filtrate of Streptomyces strain JA 2861, Sarubicin B is effective in inhibiting the growth of various pathogenic Gram-positive microorganisms. This compound is of particular interest for research applications focused on antibiotic development and the study of bacterial resistance mechanisms. -
Antitumor Antibiotic
Awamycin is an antitumor ansamycin antibiotic that primarily targets and inhibits Hsp90 (Heat shock protein 90). It exhibits potent cytotoxic activity against various cancer cell lines, making it a valuable tool for cancer research. Awamycin is utilized to study mechanisms of tumor growth and resistance, as well as to evaluate potential therapeutic strategies in oncology. -
Antibiotic
5-Hydroxy-9-methylstreptimidone is a glutarimide antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. This compound exhibits antimicrobial activity, making it valuable for studies related to bacterial resistance and antibiotic efficacy. Its biological properties facilitate research into antibiotic mechanisms and the development of new antimicrobial agents. -
Antibiotic
Milbemycin α11 is an antibiotic that exhibits potent anthelmintic and acaricidal activity. It primarily targets and disrupts the neuromuscular function of nematodes and mites, leading to their paralysis and death. This compound is useful in research applications involving parasitic infections and pest management in agricultural studies.
