Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
Corianin is a sesquiterpene lactone extracted from the fruits of Coriaria ruscifolia, exhibiting potent antibacterial properties. It demonstrates effectiveness against Staphylococcus aureus and Staphylococcus epidermidis, making it a valuable compound for research into antibacterial mechanisms and potential therapeutic applications. This compound may serve as a candidate in the development of new antimicrobial agents. -
Bacterial Inhibitor
Altertoxin III is a bacterial inhibitor known for its mutagenic effects on Salmonella typhimurium strains TA98, TA100, and TA1537. Derived from an extract of the A. alternata isolate, this compound exhibits significant mutagenicity as demonstrated in the Ames assay. It is valuable for studies focused on mutagenesis and the mechanisms of bacterial resistance. -
Antibacterial Agent
Antibacterial Agent 33 functions primarily as an antibacterial agent, exhibiting enhanced efficacy by significantly lowering the minimum inhibitory concentration (MIC) of Ceftazidime. This compound demonstrates potent antibacterial activity against a range of pathogenic bacteria, making it a valuable tool for research in antibiotic synergy and resistance mechanisms. Its applications include studies in microbiology and pharmacology, particularly in the development of novel antibacterial therapies. -
Bacterial Inhibitor
Heraclenol is a coumarin compound that targets bacterial pathogens. Isolated from the fruits of Angelica lucida, Heraclenol demonstrates notable antibacterial activity, making it valuable for research applications focused on combatting bacterial infections. Its mechanism of action contributes to the understanding of antimicrobial resistance and the development of new therapeutic strategies. -
Antibacterial Agent
Antibacterial Agent 74 is a potent anti-Salmonella compound that demonstrates significant antibacterial activity against Salmonella spp. This reagent is essential for research applications focused on understanding bacterial infections and developing novel therapeutic strategies to combat Salmonella-related diseases. -
Bacterial Inhibitor
L-689065 is a potent bacterial inhibitor that acts by targeting essential bacterial processes. It exhibits significant antimicrobial activity against a range of bacterial strains, making it a valuable reagent for studies on bacterial resistance and infection mechanisms. This compound is applicable in microbiological research focused on identifying new antibacterial agents and understanding the pathways of bacterial growth inhibition. -
Antibiotic Agent
Sulfadimethoxypyrimidine-d4 is a deuterium-labeled derivative of Sulfadimethoxypyrimidine, a sulfonamide antibiotic known for its broad-spectrum antibacterial activity. This compound acts by inhibiting bacterial dihydropteroate synthase, a key enzyme in folate biosynthesis, thereby disrupting DNA synthesis and bacterial growth. It is valuable for pharmacokinetic studies and metabolic research concerning sulfonamide antibiotics. -
Bacterial Inhibitor
FK-518 is a potent inhibitor of AmpC β-lactamase, targeting resistance mechanisms in bacteria. This compound exhibits strong antimicrobial activity against Pseudomonas aeruginosa strains that overexpress AmpC β-lactamase, making it a valuable tool in the study of bacterial infections. FK-518 is particularly useful for research investigating therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
Antibacterial Agent 197 (compound 1-deAA) functions as a termination inhibitor of non-classical anhydroglycosyl receptors and anhydrowall peptide-type peptidoglycan in bacterial TGase. This compound exhibits notable antibacterial activity against Staphylococcus aureus and can enhance the efficacy of Vancomycin, serving as an effective antibacterial adjuvant. It is suitable for research applications focused on antibiotic resistance and the development of novel antibacterial strategies. -
Antibacterial Agent
Isobavachromene is an antibacterial agent that exhibits potent activity against various bacterial strains. Its primary mechanism involves the disruption of bacterial cell wall synthesis, leading to cell lysis and death. This compound is valuable for research applications focused on exploring novel antibacterial therapies and understanding microbial resistance mechanisms. -
Antibacterial Agent
MAC173979 is an inhibitor of para-aminobenzoic acid (PABA) synthesis in Escherichia coli. This compound exhibits significant antibacterial activity, making it a valuable tool for the exploration of antibacterial drug development and mechanisms of resistance. Researchers can utilize MAC173979 to study the efficacy of novel antibacterial agents and develop therapeutic strategies targeting bacterial infections. -
Antibacterial Agent
Antibacterial Agent 43 is a potent antibacterial compound targeting bacterial strains implicated in various infections. This agent exhibits significant antimicrobial activity, making it suitable for investigating the mechanisms of bacterial resistance and the development of new therapeutic strategies. Its applications extend to research focused on treating bacterial infections and understanding the pharmacodynamics of antibacterial therapies. -
Antibacterial agent
PuroA is an antibacterial agent derived from the tryptophan-rich domain of Puroindoline a. It exerts its antibacterial activity by interacting with bacterial membranes, disrupting their integrity. This compound is valuable for research applications focused on understanding bacterial resistance and developing novel antimicrobial strategies. -
Antibacterial Agent
Tetrahydrobostrycin is a secondary metabolite derived from Aspergillus species, functioning primarily as an antibacterial agent. It demonstrates mild inhibitory activity against pathogens such as Staphylococcus aureus and Escherichia coli, with observed inhibition zones measuring 15 mm and 9.2 mm in diameter, respectively, at a concentration of 100 mg/disc. This compound may be useful in microbiological research and investigations into antibacterial mechanisms. -
Bacterial Inhibitor
RO7075573 is a bacterial inhibitor that targets the lipopolysaccharide (LPS) transport machinery in Acinetobacter species. This compound has demonstrated protective effects in preclinical models against Acinetobacter baumannii infections, highlighting its potential for therapeutic applications in combating antibiotic-resistant bacterial pathogens. Research applications may include studying bacterial pathogenesis and developing new antibiotic strategies. -
Antibacterial Agent
Tenonitrozole is an antibacterial agent that acts primarily by inhibiting pyruvate-ferredoxin oxidoreductase (PFOR). This compound exhibits notable antibacterial activity against Helicobacter pylori and Campylobacter jejuni, with minimum inhibitory concentrations (MICs) of 0.7 μM and 5.9 μM, respectively. Tenonitrozole is useful in research applications focused on bacterial infections and antibiotic resistance studies. -
Bacterial Inhibitor
Neorauflavene is a phenolic isoflavonoid derived from Neorautanenia edulis, functioning as a bacterial inhibitor. This compound exhibits significant antibacterial activity against various strains, including Enterococcus faecalis, Streptococcus suis, Streptococcus agalactiae, Pseudomonas aeruginosa, Bacillus subtilis, and Riemerella anatipestifer. Neorauflavene's antibacterial properties make it a valuable tool for research in microbiology and the development of therapeutic agents targeting bacterial infections. -
Bacterial Virulence Factor Inhibitor
Anti-virulence factor-IN-1 is a bacterial virulence factor inhibitor that disrupts the bacterial infection process. It demonstrates potent antibacterial activity against Xanthomonas oryzae pv. oryzae (Xoo) with an EC50 value of 0.28 µg/mL. This compound is applicable for the management of rice bacterial leaf blight in vivo and offers significant potential for research related to plant bacterial diseases. -
Antibacterial Agent
Antibacterial Agent 125 is an antibacterial compound that exhibits potent antimicrobial activity against clinically relevant Gram-positive pathogens, with MIC50 values ranging from 0.25 to 8 μM. This compound serves as a valuable tool in research focused on antimicrobial resistance, enabling studies to explore mechanisms of action and resistance patterns in bacterial strains. -
Antibacterial Agent
Antibacterial Agent 75, known as compound 24, functions as a potent antibacterial agent. It has demonstrated efficacy in re-sensitizing vancomycin-resistant Staphylococcus aureus (VRSA) to vancomycin, making it a valuable tool in combating antimicrobial resistance. This compound is essential for research focused on developing strategies to enhance antibiotic effectiveness against resistant bacterial strains. -
Antibacterial Agent
TXY541 is an orally active antibacterial agent that demonstrates potent activity against Staphylococcus aureus. Under physiological conditions, it can be converted to PC190723, which enhances its efficacy. TXY541 exhibits low toxicity to mammalian cells, making it suitable for various antibacterial research applications. -
Bacterial
KSK213 is a 1,2,3-triazole derivative that functions as a potent inhibitor of Chlamydia infectivity, exhibiting a half-maximal effective concentration (EC50) of less than 20 nM. This compound is valuable for research into Chlamydia infections and can aid in the development of therapeutic strategies against bacterial pathogens. Its high potency makes it an essential tool for studying bacterial infectivity mechanisms and evaluating potential antimicrobial treatments. -
Bacterial Peptide Deformylase Inhibitor
Lanopepden camsylate is a high-affinity inhibitor of bacterial peptide deformylase, an enzyme critical for protein maturation in bacteria. This compound exhibits potent activity against bacterial infections by disrupting essential protein processing. Lanopepden camsylate is primarily utilized in research applications focused on the development of new antibacterial agents and the study of bacterial pathogenicity. -
Bacterial Inhibitor
TP-271 is a bacterial inhibitor specifically designed to target pathogens associated with community-acquired pneumonia. This compound exhibits significant antimicrobial activity, making it suitable for research applications focused on bacterial infections and respiratory diseases. Its potential to disrupt bacterial growth presents promising avenues for further exploration in the development of effective therapeutics. -
Bacterial Inhibitor
Cefonicid is a broad-spectrum beta-lactam antibiotic targeting bacterial cell wall synthesis. It exhibits potent antibacterial activity against a variety of Gram-positive and Gram-negative bacteria, making it valuable in treating various infectious diseases. Pharmacokinetic studies indicate that high plasma concentrations are swiftly attained following intravenous or intramuscular administration, and its half-life may be extended with concomitant use of albendazole, leading to reduced renal clearance. Cefonicid serves as an essential tool in bacterial infection research and the development of therapeutic strategies. -
Anti-bacterial Agent
3′-Omethyl-5′-hydroxydiplacone is a C-6-geranylflavonoid with demonstrated antibacterial activity, specifically targeting Gram-positive bacteria. This compound, isolated from the ethanol extract of Paulownia tomentosa fruits, serves as a valuable tool for studies focused on bacterial inhibition and antimicrobial research. Its unique structure and functionality make it of interest for investigating the mechanisms of antibacterial agents. -
Antibacterial Agent
Antibacterial Agent 116 is a benzophenone-containing salicylanilide compound that acts by inhibiting peptidoglycan formation, a critical component of bacterial cell walls. This compound demonstrates potent antibacterial activity and serves as a photoaffinity probe to specifically label Acinetobacter baumannii penicillin-binding protein (PBP1b). Its use is vital in research applications focused on understanding bacterial growth mechanisms and developing strategies to combat antibiotic resistance. -
Bacterial Inhibitor
Penicillin N is a penicillin-type antibiotic that primarily targets bacterial cell wall synthesis. It exhibits potent antibacterial activity against enteric bacilli, making it effective for the treatment of infections caused by these pathogens. This compound is widely utilized in microbiological research to study antibacterial mechanisms and evaluate susceptibility of bacterial strains. -
Bacterial Inhibitor
Methyl sterculate is a potent bacterial inhibitor that targets Δ9 desaturase. This compound effectively inhibits the growth of Rhodococcus opacus at a concentration of 0.75 mM, demonstrating toxicity towards the bacteria. Furthermore, it alters the fatty acid profile by decreasing overall fatty acid content while increasing the palmitate ratio and reducing stearate and oleate levels at concentrations of 0.25 or 0.5 mM. Methyl sterculate also exhibits a synergistic effect on tumor growth induced by aflatoxin Q1 in rainbow trout at a concentration of 50 ppm. -
Antibacterial Agent
Cis-2-Dodecenoic acid is an antibacterial agent that disrupts bacterial quorum sensing mechanisms. Derived from Burkholderia cenocepacia, this compound effectively inhibits biofilm formation and the production of virulence factors in bacteria. Its unique action makes it valuable for research into antimicrobial resistance and biofilm-related infections. -
Bacterial Inhibitor
Quorum sensing-IN-2 is a potent quorum sensing inhibitor that targets bacterial communication mechanisms to diminish pathogenicity while preserving overall bacterial growth. This compound effectively reduces bacterial infections with minimal hemolytic activity. Additionally, Quorum sensing-IN-2 exhibits a synergistic effect when combined with Ciprofloxacin in models of Pseudomonas aeruginosa PAO1 bacteremia, making it a valuable tool for investigating bacterial virulence and developing novel therapeutic strategies. -
Quinone Antibiotic
Granaticinic acid is a quinone antibiotic derived from Streptomyces thermoviolaceus NT1. It exhibits significant anti-gram-positive bacterial activity, making it a valuable compound for researching bacterial infections. Its unique mechanism of action provides insights into antibiotic resistance and the development of new therapeutic agents. -
Antibacterial Agent
Pachyaximine A is an alkaloid derived from the root of Sarcococca hookeriana, primarily recognized for its antibacterial properties. This compound exhibits significant activity against bacterial strains, making it a valuable tool for research focused on combating bacterial infections. Its unique mechanism of action and natural origin position Pachyaximine A as an important candidate in the development of novel antibacterial agents. -
Antibacterial Agent
Antibacterial Agent 77 primarily targets bacterial cell growth. This compound exhibits significant antibacterial activity, making it suitable for research applications aimed at investigating bacterial infections and developing new antimicrobial therapies. Its effectiveness against various bacterial strains can provide insights into mechanisms of resistance and the potential for therapeutic interventions. -
Antibacterial/Anticancer Agent
AJI-9561 is a benzoxazole derivative that functions as an antibacterial and anticancer agent. This compound demonstrates significant cytotoxic effects, inhibiting the proliferation of Jurkat T cells and mouse P388 leukemia cells, with IC50 values of 0.88 µM and 1.63 µM, respectively. AJI-9561 is suitable for research focused on exploring its potential therapeutic applications in oncology and infectious diseases. -
Microbial Metabolite
Benanomicin A is a microbial metabolite derived from Actinomycetes, known for its antifungal properties. It demonstrates significant inhibitory effects on HIV-1 viral infection in MT-4 cells. This compound is useful in research applications targeting fungal infections and viral replication mechanisms. -
Antibacterial Agent
Sperabillin A is an antibacterial agent that exhibits activity against both gram-positive and gram-negative bacteria. In addition to its antibacterial properties, Sperabillin A demonstrates significant inhibition of human umbilical vein endothelial (HUVE) cell proliferation. Notably, it also displays anti-tumor activity against B16 melanoma in mouse models, making it a valuable compound for studying bacterial infections as well as cancer biology. -
Anti-bacterial Agent
(-)-Decursinol is a natural pyranocoumarin compound derived from the roots of Apiaceae plants, such as Ferulago campestris. This compound exhibits potent antibacterial activity, effectively inhibiting both Gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis, and Gram-negative bacteria such as Salmonella typhii and Enterobacter species, with minimum inhibitory concentrations ranging from 16 to 64 μg/mL. Additionally, (-)-Decursinol demonstrates antioxidant properties, making it valuable for research applications focused on bacterial infections and oxidative stress. -
Anti-bacterial Agent
Almurtide (nor-MDP) is a muramyl dipeptide derivative functioning as an anti-bacterial agent. It exhibits significant anti-inflammatory and anti-tumor properties, alongside protective effects against infections caused by Pseudomonas aeruginosa and Candida albicans in murine models. Additionally, Almurtide demonstrates inhibitory effects on the carcinogenic Friend leukemia virus, making it relevant for cancer research and infectious disease studies. -
Bacterial
N-Heptanoyl-L-homoserine lactone is an N-acyl-homoserine lactone that targets the quorum sensing mechanisms of gram-negative bacteria. This compound is involved in the regulation of gene expression, facilitating communication between bacterial cells. It is primarily utilized in research applications focused on bacterial pathogenesis and biofilm formation, providing insights into microbial behavior and interactions. -
Antibacterial Peptide
Hc-CATH is an antibacterial peptide derived from sea snake cathelicidin, exhibiting broad-spectrum antimicrobial activity. It effectively inhibits the growth of Shigella dysenteriae and Klebsiella pneumoniae, with minimum inhibitory concentrations (MIC) ranging from 0.16 mM to 20.67 mM. Additionally, Hc-CATH demonstrates anti-inflammatory properties, making it a valuable tool for research in the fields of infectious disease and inflammation. -
Antibacterial Agent
CP-74667 is a quinolone antibacterial agent with potent activity against various bacterial strains. It exhibits significant inhibitory effects on Xanthomonas maltophilia with a MIC50 of 1 μg/mL, as well as Staphylococcus spp. (MIC50 = 0.06-0.12 μg/mL) and enterococci (MIC50 = 0.5-4 μg/mL). This compound is valuable for research applications targeting bacterial infections and assessing antibiotic efficacy. -
Bacterial Inhibitor
ORM-3819 is a bacterial inhibitor targeting Staphylococcus aureus. This compound exhibits broad-spectrum antimicrobial activity against both methicillin-susceptible (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). Additionally, ORM-3819 reduces the phagocytosis of MRSA and MSSA strains by monocytic THP-1 cells, making it valuable for research related to bacterial infections and resistance mechanisms. Its efficacy in combatting staphylococcal infections positions it as a critical tool in antimicrobial studies. -
Anti-Bacterial Agent
Roseorubicin B is an anti-bacterial agent with notable activity against Gram-positive bacteria and Mycobacterium species. Additionally, it exhibits inhibitory effects on leukemia L1210 cells, with an IC50 value of 0.06 μg/mL. This compound is valuable for research applications focusing on bacterial infections and cancer therapeutics. -
Bacterial Inhibitor
4-Glycidyloxycarbazole is an antimicrobial agent that targets bacterial biofilm formation. It exhibits significant inhibitory activity against various bacterial strains, making it a valuable tool for studying bacterial behavior and infection control. This compound is useful in research applications focused on biofilm-related challenges in microbiology and infectious disease. -
Antibacterial Agent
Delmopinol is an antibacterial agent that targets oral bacteria to inhibit the formation of dental biofilm. Its primary mechanism involves interference with microbial adhesion and biofilm development, making it a valuable reagent for research focused on oral health and hygiene. This compound is especially useful in studies investigating the prevention of dental plaque and associated diseases. -
Antibacterial Agent
Antibacterial Agent 194 is a potent antibacterial compound targeting Mycobacterium tuberculosis (Mtb). It exhibits significant antimicrobial activity with a minimum inhibitory concentration (MIC) of 1 μg/mL. This agent is valuable for research applications focused on combating tuberculosis and understanding the mechanisms of bacterial resistance. -
Antibacterial Agent
SCUT1-2 is a bifunctional antibacterial agent targeting Clostridium difficile. It demonstrates significant antibacterial activity, effectively killing vegetative cells with a minimum inhibitory concentration (MIC) of 0.06-0.50 μg/mL, while also inhibiting spore germination in vitro. In preclinical models, SCUT1-2 has shown efficacy in alleviating symptoms associated with C. difficile infection, including weight loss and diarrhea, and in preventing recurrent infections. -
Antibacterial agent
Anti-MRSA agent 16 is an inhibitor of methicillin-resistant Staphylococcus aureus (MRSA). This compound demonstrates potent antibacterial activity and shows enhanced efficacy when used in combination with oxacillin or meropenem in in vivo models, specifically in infected mice. It is a valuable tool for researchers investigating treatments for MRSA infections. -
Antibacterial Agent
BMY-28271 is an orally active cephalosporin that functions as a potent antibacterial agent. It exhibits a broad spectrum of activity against both gram-positive and gram-negative bacteria, making it a valuable compound for combating bacterial infections. Additionally, BMY-28271 demonstrates resistance to hydrolysis by various beta-lactamases, enhancing its efficacy in research applications focused on infection treatment and antibiotic resistance mechanisms.
