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FK-518

Catalog No.: A49386
Bacterial Inhibitor
FK-518 is a potent inhibitor of AmpC β-lactamase, targeting resistance mechanisms in bacteria. This compound exhibits strong antimicrobial activity against Pseudomonas aeruginosa strains that overexpress AmpC β-lactamase, making it a valuable tool in the study of bacterial infections. FK-518 is particularly useful for research investigating therapeutic strategies against resistant bacterial strains.
FK-518 1025510-45-5 Bacterial Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFK-518 is a potent inhibitor of AmpC β-lactamase, targeting resistance mechanisms in bacteria. This compound exhibits strong antimicrobial activity against Pseudomonas aeruginosa strains that overexpress AmpC β-lactamase, making it a valuable tool in the study of bacterial infections. FK-518 is particularly useful for research investigating therapeutic strategies against resistant bacterial strains.
Product Information
Catalog NumA49386
FormulaC21H26ClN9O8S2
Molecular Weight632.07
CAS Number1025510-45-5
SMILESOCC[N+](N1CC(CS[C@]2([H])[C@@H]3NC(/C(C4=NSC(N)=N4)=N\OC(C)(C(O)=O)C)=O)=C(C(O)=O)N2C3=O)=C(C=C1)N.[Cl-]
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Microbiology > Antifection > Bacterial