Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Boromycin is an antibiotic that targets bacterial ribosomes, inhibiting protein synthesis. Isolated from Streptomyces antibioticus, it exhibits potent activity against a range of gram-positive bacteria. This compound is valuable for research applications related to antimicrobial resistance and the development of new therapeutic agents. -
Peptide Antibiotic
Clavanin A is a peptide antibiotic that disrupts the integrity of the cytoplasmic membrane in target cells. It demonstrates effective bactericidal activity against Micrococcus flavus, making it a valuable tool for studying bacterial membrane dynamics and antibiotic mechanisms. Researchers can utilize Clavanin A for investigations into microbial resistance and the development of new antimicrobial strategies. -
Antibiotic
Altersolanol B, a fungal-derived compound, exhibits antibiotic properties through its ability to induce ATP catabolism in Ehrlich ascites tumor cells. This molecular action highlights its potential as a research tool for studying cellular energy dynamics and responses to antimicrobial agents. Altersolanol B may contribute to the understanding of antibiotic mechanisms and resistance patterns in cancer biology. -
Antibiotic
Ranbezolid is an orally active oxazolidinone antibiotic primarily targeting Gram-positive and Gram-negative anaerobes, including Staphylococcus aureus and Bacteroides fragilis. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, demonstrating an IC50 of 17 μM. Ranbezolid is effective in rapidly reducing bacterial load and has an enhanced cardiovascular safety profile. This compound is valuable for research applications focused on antibiotic effects against anaerobic bacteria. -
Sulfur-containing Antibiotic
Tropodithietic acid is a sulfur-containing antibiotic derived from the marine bacterium Phaeobacter inhibens. It demonstrates potent antibacterial activity against a wide range of bacterial species, including alpha- and gammaproteobacteria, flavobacteria, and actinobacteria. This compound is valuable for research applications involving antimicrobial resistance and the study of microbial interactions in marine environments. -
Antibiotic, Insecticide
Cafamycin is a polyether antibiotic that targets gram-positive bacteria, notably Staphylococcus aureus. In addition to its antibacterial properties, Cafamycin exhibits insecticidal and antiprotozoal activities. It is isolated from the culture fluid of Streptomyces sp., an organism recognized for producing various bioactive compounds, including the anthracycline antibiotic galtamycin. This compound is valuable for research applications in microbiology and pest control. -
Antibacterial Peptide
KT2 is a cationic amphipathic antibacterial peptide that targets bacterial membranes. It exhibits potent antibacterial activity against E. coli O157:H7, demonstrating complete bactericidal effects and significant inhibition of biofilm formation. KT2 interacts with bacterial surface lipopolysaccharides (LPS) and penetrates lipid layers, facilitating its binding to DNA and other cytoplasmic components, making it a valuable reagent for research in antimicrobial therapies and biofilm-related studies. -
Bacterial Inhibitor
Anhydroerythromycin A is a bacterial inhibitor derived from the degradation of the macrolide antibiotic erythromycin. It exhibits antimicrobial activity against Staphylococcus aureus and Bacillus cereus, with minimum inhibitory concentrations of 12.5 µg/ml and 6.25 µg/ml, respectively. Additionally, Anhydroerythromycin A inhibits steroid 6β-hydroxylase activity linked to the cytochrome P450 isoform CYP3A in human liver microsomes, making it a valuable tool for studying bacterial resistance and metabolic pathways. -
Bacterial Inhibitor
Cefsulodin is a bacterial inhibitor primarily targeting Pseudomonas aeruginosa. It exhibits potent antimicrobial activity against penicillin-susceptible and gentamicin-sensitive strains, demonstrating effectiveness comparable to gentamicin and debendazole. However, Cefsulodin's efficacy is reduced against penicillin-resistant strains of P. aeruginosa, particularly those also resistant to gentamicin. The compound shows a similar minimum inhibitory concentration for P. aeruginosa maltofila when compared to penicillin, gentamicin, and debendazole, while Pseudomonas cepacia strains typically present moderate resistance to Cefsulodin. Its applications include evaluating bacterial resistance mechanisms and antibiotic efficacy in clinical microbiology. -
Antibiotic
Avilamycin A is an orally active antibiotic that targets bacterial pathogens, particularly effective against veterinary strains of Clostridium perfringens (MICs ≤ 0.06-0.5 mg/L) and Brachyspira hyodysenteriae (MICs = 12.5-100 μg/ml). Its potent antibacterial properties make it a valuable reagent for research focused on combating bacterial infections in veterinary medicine. Avilamycin A is often utilized in studies aiming to understand antibiotic resistance mechanisms and to develop new therapeutic strategies against resistant bacterial strains. -
Antibiotic
(R)-10,11-Dehydrocurvularin is an antibiotic derived from the secondary metabolites of Curvularia species. It exhibits concentration-dependent cytotoxicity against various human tumor cell lines, with a mean IC50 value of 1.25 µM. This compound is valuable for research applications in cancer biology and the development of novel antimicrobial agents. -
Antibiotic
Erythromycin C is an antibiotic that primarily targets bacterial protein synthesis by binding to the 50S ribosomal subunit. It exhibits potent activity against a wide range of gram-positive bacteria and some gram-negative pathogens. Erythromycin C is widely used in research to study bacterial resistance mechanisms and as a model compound in antibiotic development studies. Its properties make it a valuable tool in microbiological and pharmaceutical research. -
Diterpene Ester
12-Deoxyphorbol-13-isobutyrate-20-acetate is a diterpene ester that functions as a selective agonist of protein kinase C (PKC). It effectively activates PKC to facilitate the phosphorylation of troponin I and troponin T, contributing to key regulatory pathways in cardiac function. Additionally, this compound has been shown to induce dermal irritation and necrosis in murine models while demonstrating no cocarcinogenic activity. Furthermore, 12-Deoxyphorbol-13-isobutyrate-20-acetate exhibits inhibitory effects on the growth of Aspergillus carbonarius, making it valuable for research in heart failure, cardiomyopathies, and fungal infections. -
Antifugal Agent
Polyoxin D is a potent antifungal agent that acts as a chitin synthetase inhibitor. By disrupting chitin synthesis in fungal cell walls, it effectively inhibits fungal growth and proliferation. This compound is primarily utilized in research settings to study fungal pathogenesis and to explore potential therapeutic strategies against fungal infections. -
Bacterial Inhibitor
Ampicillin is a broad-spectrum beta-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable reagent in microbiological research and antibiotic susceptibility testing. Ampicillin is commonly used to study bacterial resistance mechanisms and is also employed in molecular biology for the selection of recombinant plasmids in cloning applications. -
SPT Inhibitor
Myriocin is a potent serine palmitoyltransferase (SPT) inhibitor derived from various fungal species such as Myriococcum albomyces, Isaria sinclairi, and Mycelia sterilia. By inhibiting SPT, Myriocin plays a crucial role in the disruption of de novo sphingolipid synthesis. It has demonstrated significant antiviral activity, effectively suppressing the replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL. This compound is valuable for research into sphingolipid metabolism and hepatitis C virus infection mechanisms. -
Antibiotic
Concanamycin A is a macrolide antibiotic that functions as an inhibitor of vacuolar type H+-ATPase (V-ATPase). By inhibiting V-ATPase, Concanamycin A disrupts lysosomal acidification, making it a valuable tool in the study of T cell-mediated inflammation. Its properties allow for exploration of cellular processes related to inflammation and lysosomal function, contributing to a better understanding of various disease mechanisms. -
Antibiotic
Streptomycin is an aminoglycoside antibiotic primarily targeting bacterial protein synthesis by binding to ribosomal RNA. It exhibits potent activity against Mycobacterium tuberculosis, making it essential for tuberculosis research. In addition, Streptomycin demonstrates bactericidal properties against various bacterial infections and interferes with nucleic acid interactions. Furthermore, this compound acts as a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes, enabling its use in studies related to electrophysiological processes. -
Bacterial Metabolite
Palmitoyl serinol is a bacterial metabolite analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). It exhibits enhanced activity in improving the epidermal permeability barrier, demonstrating efficacy in both normal and inflamed skin conditions. Its unique properties make it a valuable tool for research into skin barrier function and inflammation-related studies. -
HIV-I Integrase Inhibitor
Bis-T-23 is a potent inhibitor of HIV-1 integrase, acting through a tyrphostin derivative mechanism. This compound has been shown to promote actin-dependent dynamin oligomerization, highlighting its role in cellular processes related to viral replication. Bis-T-23 is valuable for research focused on HIV and chronic kidney diseases (CKD), providing insights into the intersection of viral infection and renal pathophysiology. -
Myosin I Inhibitor
ZJS178 is a selective inhibitor of myosin I, exhibiting significant antifungal activity against Fusarium graminearum. This compound effectively reduces the synthesis of the mycotoxin deoxynivalenol (DON) and is valuable for research on plant diseases, particularly wheat scab. ZJS178 serves as a potent tool for studies aimed at understanding myosin I functions in fungal pathogenesis and developing strategies for disease management in crops. -
Bacterial Inhibitor
Allergen Gal d 4 (46-61), chicken is a peptide derived from hen egg white lysozyme, exhibiting bacterial inhibitory activity. This compound is utilized in research related to allergenic responses and microbial interactions, making it significant in studies of food allergies and immunological reactions. Its targeted application in bacterial inhibition aids in understanding the role of allergens in various biological systems. -
Antibacterial Agent
Maniladiol is a triterpenoid that serves as an antibacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 4 mg/mL against the H37Rv strain of M. tuberculosis. This compound is valuable for research focused on tuberculosis infection mechanisms and potential therapeutic applications. -
Antibacterial Agent
8-Desmethyleleutherin is an antibacterial agent derived from the bulbs of Eleutherine americana. It exhibits potent antibacterial activity with minimal inhibitory concentration (MIC) values of 62.5 µg/mL against Staphylococcus aureus strains ATCC27664 and ATCC25923. This compound is valuable for research applications focusing on bacterial resistance and the development of new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 80 is an antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant inhibitory activity against a wide range of gram-positive and gram-negative bacteria. This reagent is valuable for research applications aimed at investigating bacterial resistance mechanisms and developing novel antimicrobial therapies. -
Antibacterial Agent
Xanthoascin is a natural phenolic metabolite that exhibits strong antibacterial activity. Derived from the fermentation products of the endophytic fungus Aspergillus sp. IFB-YXS found in Ginkgo biloba leaves, Xanthoascin demonstrates a minimum inhibitory concentration (MIC) of 0.3125 µg/mL against Clavibacter michiganense subsp. sepedonicus, along with moderate activity against other bacterial pathogens (MIC = 5-20 µg/mL). Its mechanism involves disrupting bacterial cell membrane permeability, resulting in the leakage of nucleic acids. This compound holds potential for research applications in antimicrobial development and the study of plant pathogen interactions. -
Antibacterial Agent
Penamecillin is an acetoxymethyl ester of Penicillin G designed as an orally active antibacterial agent. It acts by inhibiting bacterial cell wall synthesis, rendering it effective against a range of gram-positive bacteria. This compound is primarily utilized in research applications focused on understanding bacterial resistance and the pharmacodynamics of antibiotic treatments. -
Antibacterial Agent
Anti-MRSA agent 8 is a DAPG derivative that exhibits potent antibacterial activity. This compound targets bacterial cell membranes, disrupting their integrity and function. It is particularly valuable for research focused on methicillin-resistant Staphylococcus aureus (MRSA), making it an essential tool for studies on antibiotic resistance and bacterial infection. -
Antibacterial Agent
Antibacterial Agent 57 is an antibacterial compound that exhibits potent activity against a variety of bacterial strains. Its primary mechanism involves the inhibition of bacterial growth, making it a valuable tool for research applications focused on antimicrobial resistance and the development of new therapeutic agents. This compound is essential for studies investigating the efficacy of novel antibacterial therapies and understanding bacterial pathogenesis. -
Bacterial Inhibitor
Levonadifloxacin arginine is a potent bacterial inhibitor targeting both methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA). This broad-spectrum antistaphylococcal agent exhibits significant antimicrobial activity and has been shown to reduce the phagocytosis of MRSA and MSSA strains by monocytic THP-1 cells. Its applications in research include studies focused on bacterial resistance mechanisms and potential therapeutic interventions for staphylococcal infections. -
Antibacterial Agent
WU-FA-01 is a hydrogenated derivative of WU-FA-00, functioning primarily as an antibacterial agent. It demonstrates potent antibacterial activity against Gram-positive bacterial strains, making it a valuable compound for research into antimicrobial therapies. Additionally, WU-FA-01 exhibits some anti-inflammatory properties, suggesting potential applications in studies focused on the interplay between bacterial infections and inflammation. -
Antibacterial Agent
Isomagnolol is a lignan known for its antibacterial properties. Isolated from the roots of the tea plant, it exhibits significant antimicrobial activity, making it a valuable reagent for research focused on combating bacterial infections. This compound can be utilized in studies investigating the mechanisms of action behind antibacterial agents and in the development of novel therapeutic strategies. -
Bacterial Inhibitor
Antibacterial Agent 53 is a potent bacterial inhibitor that targets specific bacterial pathways to disrupt cell function. Demonstrating significant antibacterial activity, this compound is primarily utilized in research focusing on the development of novel antimicrobial agents and therapeutic strategies against bacterial infections. Its effectiveness makes it a valuable reagent for studies aimed at understanding bacterial resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 109 is an effective antibacterial compound that targets protein synthesis by inhibiting the elongation of peptide chains. It demonstrates strong activity against both gram-positive and gram-negative bacteria while exhibiting non-mutagenic properties. This compound is suitable for research applications focused on bacterial resistance and the mechanisms of antibiotic action. -
Bacterial Inhibitor
Anti Gram-Positive/Negative Bacteria Agent 1 is a bacterial inhibitor that functions through the mechanism of an antibiotic conjugate linked to an artificial MECAM-based siderophore. This compound exhibits significant antibacterial activity against both Gram-positive and Gram-negative bacteria. It is suitable for research applications aimed at studying bacterial infections and developing new antimicrobial strategies. -
Antibacterial Agent
Antibacterial Agent 117 is a triazole derivative that functions as an effective antibacterial agent targeting MetAP1 in Rickettsia prowazekii, exhibiting an IC50 value of 15 μM. This compound demonstrates the ability to inhibit rickettsial growth, making it valuable for research focused on infectious diseases. Its potential applications include investigating mechanisms of bacterial resistance and developing therapeutic strategies against rickettsial infections. -
Antibacterial Agent
ST166 free acid is an inhibitor of the PhoP-DNA complex formation, exhibiting IC50 values of 18 µM and 24 µM against PhoP and MtrAC binding to DNA, respectively. This compound demonstrates significant antibacterial activity against Macrobacterium marinum, making it a valuable tool for studying bacterial infections and pathways. Its application in research contributes to the understanding of bacterial resistance mechanisms and the development of novel antibacterial strategies. -
Bacterial Inhibitor
Antitubercular agent-9 is a bacterial inhibitor that demonstrates effective antitubercular activity, with a minimum inhibitory concentration (MIC) ranging from 1.03 to 2.32 μM. This compound is suitable for research focused on tuberculosis treatment mechanisms and the development of new antitubercular therapies. It serves as a valuable tool for understanding bacterial resistance and evaluating potential drug candidates in infectious disease research. -
Antibacterial Agent
Antibacterial Agent 143 (Compound 5a) is a synthetic antibacterial agent that demonstrates effective antimicrobial activity with minimum inhibitory concentrations (MICs) of 25 μg/mL against Bacillus subtilis ATCC 6633 and Staphylococcus aureus ATCC 6538, and 50 μg/mL against Pseudomonas aeruginosa ATCC 13525 and Escherichia coli ATCC 35218. Its potency against a range of Gram-positive and Gram-negative bacteria makes it a valuable tool in antibacterial research and the development of novel therapeutic strategies. This compound is suitable for studies focusing on bacterial resistance mechanisms and the evaluation of new antibacterial formulations. -
Bacterial Inhibitor
Antibacterial Agent 62 is a novel redox cycling compound that targets bacterial cells, demonstrating potent bactericidal activity against both growing and nutrient-starved phenotypically drug-resistant nongrowing bacteria. This reagent is particularly useful in research applications focused on tuberculosis and the development of new antibacterial therapies. Its unique mechanism of action may also aid in understanding resistance mechanisms in various bacterial strains. -
Antibacterial Agent
D-K6L9 is an antibacterial agent that exhibits significant antimicrobial and antibiofilm activities against Pseudomonas aeruginosa strains isolated from cystic fibrosis patients. This compound demonstrates stability and resistance to degradation by proteases found in cystic fibrosis sputum, which contributes to its effective performance. Importantly, D-K6L9 does not promote bacterial resistance, making it a valuable tool for research in infectious diseases associated with cystic fibrosis. -
Antibacterial Agent
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] is a cyclic peptide exhibiting potent antibacterial properties, effective against both drug-resistant Gram-positive and Gram-negative bacteria. It demonstrates minimum inhibitory concentrations (MICs) of 3.1 µg/mL against MRSA (ATCC BAA-1556) and S. aureus (ATCC 29213), and 12.5 µg/mL and 25 µg/mL against P. aeruginosa (ATCC 27883) and E. coli (ATCC 25922), respectively. This compound serves as a crucial tool for researchers exploring novel antibacterial strategies and understanding resistance mechanisms in pathogenic bacteria. -
Antibacterial Agent
Antibacterial Agent 46 is a potent antibacterial agent, specifically developed for targeting bacterial infections. It demonstrates significant inhibitory activity against a range of pathogenic bacteria, making it a valuable tool for research in the field of microbiology. This compound can be utilized in studies aimed at understanding bacterial resistance mechanisms and developing new antibacterial therapies. -
Bacterial Inhibitor
Antibacterial Agent 30 is a potent bacterial inhibitor, exhibiting significant in vitro activity against Xanthomonas oryzae pv. oryzae with an EC50 value of 1.9 μg/mL. This compound is suitable for research applications aimed at understanding bacterial pathogenesis and developing new antibacterial strategies. -
Bacterial Inhibitor
NDM-1 inhibitor-2 is a selective inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) that effectively inhibits NDM-1 enzymatic activity. This compound demonstrates significant antibacterial activity against drug-resistant bacterial strains that overexpress NDM-1, providing insights into overcoming resistance mechanisms. Additionally, NDM-1 inhibitor-2 can enhance the efficacy of the carbapenem antibiotic meropenem, resulting in a synergistic effect that supports research in antimicrobial therapy and resistance management. -
Antibacterial Drug
1,3,7-Trihydroxy-2-prenylxanthone is a xanthone derivative with antibacterial properties primarily targeting vancomycin-resistant enterococci (VRE). It demonstrates a minimum inhibitory concentration (MIC) of 6.25 mg/ml against strains including Enterococcus faecalis, Enterococcus faecium, and Enterococcus gallinarum. This compound is valuable for research applications focused on antibiotic resistance and the development of novel antibacterial agents. -
Antibacterial Drug
(±)-ε-Viniferin is a racemic mixture known for its antibacterial properties, primarily targeting Gram-positive bacteria. It demonstrates antimicrobial activity against Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) of 20 μM. Additionally, (±)-ε-Viniferin exhibits P450 inhibitory effects and protective properties for hepatocytes, making it a valuable compound in research on antibacterial agents and hepatoprotection. -
Bacterial Inhibitor
1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial agent targeting a range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). Its significant antibacterial activity makes it a valuable candidate for addressing drug-resistant bacterial infections. Research applications may include investigations into its efficacy as a therapeutic tool against prevalent multidrug-resistant pathogens in clinical settings. -
Antibacterial Peptide
LDKA is a helical membrane-active antibacterial peptide that primarily disrupts bacterial membranes. This compound demonstrates significant antibacterial activity against both Gram-positive bacteria, such as Staphylococcus aureus, and Gram-negative bacteria, including Escherichia coli and Pseudomonas aeruginosa, in nutrient-rich environments. The minimum inhibitory concentrations (MICs) for LDKA range from 10 to 70 μM, making it a valuable tool for research in antibacterial therapeutic development. -
Antibacterial Drug
Galbinic acid (α-Acetylsalazinic acid) is an antibacterial compound that targets and inhibits the growth of various bacterial strains. It demonstrates significant activity against Gram-positive bacteria such as Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus, with minimum inhibitory concentrations (MICs) of 62.5 μg/ml and 250 μg/ml, respectively. Additionally, Galbinic acid exhibits antibacterial effects on the Gram-negative bacterium Escherichia coli, with an MIC of 125 μg/ml. This compound is valuable for research applications focused on developing new antibacterial agents.
