Antifection

Items 4051-4100 of 4946

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Product Name
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  1. Anti-Bacterial Agent

    Pacidamycin 2 is an antibacterial agent that primarily targets and inhibits Pseudomonas aeruginosa. It also demonstrates activity against various strains of bacteria, including Suppurative Staphylococcus and Escherichia coli. This compound is useful in antibacterial research and investigation of microbial resistance.
  2. Antibacterial Peptide

    CP7-FP13-2 is an antibacterial peptide that targets virulence factors in bacteria. It effectively inhibits the formation of biofilms in Staphylococcus aureus, demonstrating potent antibacterial activity in in vivo mouse models. This compound is valuable for research applications focusing on microbial resistance and the development of alternative therapeutic strategies against bacterial infections.
  3. Antibacterial Agent

    γ-Rubromycin is a natural compound derived from Streptomyces, primarily acting as an antibacterial agent. It exhibits significant antibacterial activity, making it a valuable tool for exploring microbial resistance mechanisms and developing new therapeutic strategies against bacterial infections. This reagent is suitable for research applications focused on antimicrobial efficacy and the biochemical pathways associated with bacterial pathogens.
  4. Antibacterial Agent

    Beauvericin A is a cyclodepsipeptide with potent antibacterial activity, primarily targeting Mycobacterium tuberculosis and Plasmodium falciparum. It exhibits a minimum inhibitory concentration (MIC) of 25 μg/mL against M. tuberculosis and an IC50 of 12 μg/mL against P. falciparum, demonstrating its potential as a valuable agent in infectious disease research. Additionally, Beauvericin A shows toxicity to brine shrimp, indicating its bioactive properties that can be explored in various biological assays.
  5. Antibacterial Agent

    Norfloxacin succinil is a quinolone antibacterial agent that targets bacterial DNA gyrase and topoisomerase IV, leading to the inhibition of DNA replication and repair. This compound exhibits effective antimicrobial activity against a range of Gram-negative and Gram-positive bacteria. It is primarily utilized in research related to infectious diseases, particularly in the study of urinary tract infections.
  6. Antibacterial Agent

    Antibacterial Agent 281 specifically targets the growth of Streptococcus pyogenes (GAS) through bacteriostatic inhibition. This compound binds to the ligand binding pocket of SPs0871, effectively competing with the native ligand. Antibacterial Agent 281 demonstrates concentration-dependent inhibition of S. pyogenes growth, making it a valuable tool for research into antibacterial mechanisms and therapeutic development.
  7. Anti-Bacterial Agent

    Kibdelin B is an anti-bacterial agent that targets Gram-positive bacteria, exhibiting significant activity against Staphylococcus aureus, including methicillin-resistant strains (MRSA). Its mechanism of action parallels that of Vancomycin, making it a valuable compound for research applications in developing new therapeutic strategies against resistant bacterial infections.
  8. Anti-Bacterial Agent

    Amidinomycin is an antibacterial agent that primarily targets Gram-positive bacteria. It exhibits moderate antibacterial activity, making it useful for studying bacterial resistance mechanisms and evaluating potential therapeutic strategies. Its efficacy in inhibiting Gram-positive strains positions it as a valuable reagent for microbiological research and drug development.
  9. Antioxidant/Antibacterial Agent

    Eriodictyol 7, 3'-dimethyl ether is a flavonoid compound known for its antioxidant and antibacterial properties. Extracted from Berberis riparia, this compound demonstrates significant potential in mitigating oxidative stress and inhibiting bacterial growth. It is valuable for research applications focused on natural antioxidants and the development of antibacterial agents.
  10. Anti-Bacterial Agent

    Saframycin Mx2 is an anti-bacterial agent that exhibits potent activity against both Gram-positive and Gram-negative bacteria. Its mechanism involves the inhibition of bacterial growth, making it valuable for research applications focused on antibiotic development and studies in microbial resistance. Saframycin Mx2 is suitable for use in various biological assays and exploration of antibacterial efficacy.
  11. Anti-Bacterial Agent

    Peptaibolin is an anti-bacterial agent primarily targeting Gram-positive bacteria and yeast. It exhibits inhibitory activity against Staphylococcus subtilis ATCC 6633 and Candida albicans, with minimum inhibitory concentrations (MICs) of 100 μg/mL for both organisms. Due to its selective activity, Peptaibolin is useful for research applications aimed at understanding bacterial and fungal resistance mechanisms.
  12. Antibiofilm Agent

    Antibiofilm agent-14 is a potent antibiofilm agent targeting fungal biofilm formation. It exhibits notable antifungal activity against Candida albicans strain SC5314, demonstrating a minimum inhibitory concentration (MIC) of 50 μM. This compound is valuable for research applications focusing on biofilm-related infections and strategies to combat fungal resistance.
  13. Anti-Bacterial Agent

    Chimeramycin A is an antibiotic compound that exhibits potent anti-Gram-positive bacterial and mycoplasma activity. It disrupts bacterial protein synthesis, making it an effective agent in combating infections caused by resistant strains. This compound is valuable for research applications focused on antibiotic resistance and the development of new antibacterial therapies.
  14. Anti-Bacterial Agent

    Griseochelin is an anti-bacterial agent known for its robust activity against Gram-negative bacteria. Additionally, it demonstrates inhibitory effects on Coccidioides species, making it a valuable compound for research into fungal infections. Its unique properties make it suitable for investigations in both antimicrobial and antifungal applications.
  15. Bacterial Inhibitor

    o-Cymen-5-ol acts as a broad-spectrum antimicrobial agent targeting various bacterial and fungal pathogens. It demonstrates effective minimum inhibitory concentrations (MICs) against organisms such as Streptococcus mutans and Candida albicans. Notably, o-Cymen-5-ol exhibits synergistic effects when combined with zinc, enhancing its antimicrobial activity against oral pathogens by inhibiting glycolysis. Studies indicate a more pronounced antibacterial effect in formulations such as toothpaste compared to placebo. This compound is valuable for research applications in microbiology and dental health.
  16. Anti-Bacterial Agent

    Cephaibol D is an anti-bacterial agent derived from the Acremonium tubae strain DSM 12774. This compound exhibits weak antibacterial activity, making it a candidate for exploring mechanisms of antimicrobial resistance and the development of novel therapeutic agents. Its potential applications include studying bacterial metabolism and assessing the efficacy of various antimicrobial strategies.
  17. Antibacterial Agent

    GDI-5755 is an antibacterial agent that targets and inhibits ClpP1P2, effectively reducing the growth of Mycobacterium tuberculosis and Mycobacterium bovis BCG. This compound is relevant for research applications focused on tuberculosis (TB) and provides a valuable tool for the study of mycobacterial infections. Its mechanism of action makes GDI-5755 a promising candidate for further investigation in the development of therapeutic strategies against TB.
  18. Anti-Bacterial Agent

    Phencomycin is an anti-bacterial agent with a modest inhibitory effect on Gram-positive bacteria. Additionally, it targets the enzyme renin, affecting its activity with an IC50 of 440 μg/mL. This compound is useful in studies focused on bacterial resistance and enzyme modulation in physiological processes.
  19. Antibacterial Agent

    Arizonin C1 is a microbial metabolite that functions as an antibacterial agent targeting Gram-positive bacteria. It exhibits significant antimicrobial activity, making it a valuable compound for research in the study of bacterial infections and the development of new antimicrobial therapies. Arizonin C1's unique properties contribute to its potential applications in antibiotic resistance studies and the discovery of novel antibacterial agents.
  20. Antibacterial Drug

    LY 215891 is an antibacterial agent that demonstrates potent activity against both Gram-positive and Gram-negative bacteria. It achieves minimum inhibitory concentrations (MICs) of 0.015 μg/mL against Klebsiella pneumoniae X26 and 0.06 μg/mL against Escherichia coli EC14. This compound is valuable for research applications focusing on the development of novel antibacterial therapeutics and the study of bacterial resistance mechanisms.
  21. Anti-Bacterial Agent

    Neoviridogrisein I is an anti-bacterial agent that selectively inhibits the growth of Gram-positive bacteria and mycoplasma. Its biological activity makes it a valuable tool in microbiological research and the study of bacterial resistance mechanisms. This compound can be employed in various experimental settings to further investigate bacterial pathogenesis and develop potential therapeutic strategies.
  22. Antibiotic

    Sannamycin J is an aminoglycoside antibiotic that exhibits antimicrobial properties. Isolated from Streptomyces sannanensis sp. KC-7038, it demonstrates weak antibacterial activity against both Gram-positive and Gram-negative bacteria. This compound serves as a valuable tool for research in antibiotic mechanisms and microbial resistance studies.
  23. Anti-Bacterial Agent

    Monorden C is an anti-bacterial agent that effectively arrests the cell cycle of Jurkat cells in the G1 and G2/M phases. This compound demonstrates significant anti-Aspergillus niger activity, making it a valuable tool in research focused on fungal infections and cell cycle regulation. Its mechanisms of action provide insights into cellular responses to bacterial and fungal challenges, facilitating studies in both microbiology and cell biology.
  24. Anti-Bacterial Agent

    Azicemicin B is an antibacterial agent that exhibits weak antimicrobial activity. Its low toxicity profile has been demonstrated in mouse models, making it a candidate for further evaluation in microbial research and potential therapeutic applications. This compound may be useful in studies exploring the mechanisms of bacterial resistance and the development of novel antibacterial strategies.
  25. Anti-Bacterial Agent

    Emerimicin IV is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria. It interferes with bacterial protein synthesis, making it a valuable compound for research focused on developing new antimicrobial therapies. This reagent is particularly useful in studies investigating bacterial resistance and the mechanisms of action of antibiotics.
  26. Anti-Bacterial Agent

    Lactonamycin is an anti-bacterial agent known for its potent activity against Gram-positive bacteria, specifically Staphylococcus, Streptococcus, Enterococcus, MRSA, and VRE, with minimum inhibitory concentrations (MIC) ranging from 0.39 to 0.78 μg/mL. Additionally, Lactonamycin demonstrates cytotoxic effects on various tumor cell lines, including L-1210, P388, S180, FS-3, Ehrlich, and B16-BL5, exhibiting IC50 values between 0.06 and 3.3 μg/mL. This compound is valuable for research focused on bacterial resistance and cancer therapeutics.
  27. Anti-Bacterial Agent

    Nocathiacin II is a potent anti-bacterial agent primarily effective against Gram-positive bacteria. It demonstrates significant resistance to strains such as methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP), and multidrug-resistant Enterococcus faecalis (MREF). This compound is ideal for research applications focused on combating antibiotic resistance and developing effective antibacterial therapies.
  28. Bacterial Inhibitor

    Strinoline is a bacterial inhibitor that targets and disrupts bacterial cell function. This compound exhibits significant antibacterial activity, making it a valuable tool for research in the field of microbiology. Strinoline can be utilized to study bacterial resistance mechanisms and the efficacy of antibiotic therapies.
  29. Antibiotic

    Trinactin is a macrotetrolide antibiotic that displays potent antibacterial activity through the disruption of bacterial cell membranes. Additionally, it functions as a cation carrier, facilitating ion transport across cellular membranes. This compound is significant for research applications focused on antibiotic development, cellular ion exchange mechanisms, and studying the effects of ionophore activity in various biological systems.
  30. Anti-Bacterial Agent

    Enaminomycin C is an anti-bacterial agent with a demonstrated ability to inhibit the growth of Gram-positive bacteria. Its activity profile shows weak effectiveness against Gram-negative bacteria, making it a candidate for further investigation in antibacterial research. Studies involving Enaminomycin C may contribute to the development of new therapeutic strategies against bacterial infections.
  31. Antibacterial Agent

    Tacapenem, the active metabolite of CS-834, functions as a potent antibacterial agent. It demonstrates a broad spectrum of antibacterial activity against both gram-positive and gram-negative aerobes and anaerobes. Notably, Tacapenem exhibits strong bactericidal effects against Staphylococcus aureus and Escherichia coli, making it a valuable tool for research in bacterial infections and antibiotic resistance studies.
  32. Antibacterial Agent

    Antibacterial agent 170 (compound 6b) is a potent antibacterial compound that targets the inhibition of biofilm formation in Pseudomonas aeruginosa PAO1. It demonstrates significant activity as a quorum sensing inhibitor through the las system, effectively disrupting bacterial communication and biofilm development. This agent is valuable for studies focused on microbial resistance and the mechanisms underlying bacterial pathogenicity.
  33. Antibacterial Agent

    Colupulone is a β-acid resin derived from hops (Humulus lupulus) known for its antibacterial properties. It demonstrates significant activity against a range of bacteria as well as anti-larval effects on Culex mosquitoes. This compound is useful for investigations into infectious diseases and the development of novel antibacterial agents.
  34. Anti-Bacterial Agent

    Kerriamycin C is an anti-bacterial agent targeting Gram-positive bacteria. It exhibits significant antibacterial activity, making it valuable for research in infectious disease and antimicrobial resistance. Additionally, Kerriamycin C has shown the ability to inhibit ascites cancer in experimental models, suggesting potential applications in cancer research.
  35. Antibacterial Agent

    Anti-MRSA Agent 37 is an antibacterial agent specifically targeting methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) of 0.25-0.5 μg/mL. This compound effectively inhibits biofilm formation, disrupts cell wall integrity, compromises cell membrane stability, and induces oxidative stress in bacterial cells. It holds potential for research applications related to MRSA-associated diseases, particularly skin infections.
  36. Antibiotic

    2'''-Hydroxychlorothricin is an antibiotic derived from the chlorothricin group, primarily targeting bacterial infections. Isolated from Streptomyces sp. K818, it exhibits anti-tumor properties and has been shown to extend the survival of ICR mice inoculated with Ehrlich cancer cells. This compound serves as a valuable tool in cancer research and microbiological studies focusing on antibiotic efficacy and tumor treatment.
  37. Bacterial Metabolite

    Steffimycin B is an anthracycline bacterial metabolite derived from Streptomyces, possessing a primary mechanism of DNA binding through preferential intercalation at cytosine and guanine-rich regions. It exhibits significant cytotoxicity against various cell lines, including MCF-7, KB, NCI-H187, and Vero cells, with IC50 values of 3.5, 6.75, 3.28, and 10.5 μM, respectively. Furthermore, Steffimycin B demonstrates potent antimicrobial activity against Mycobacterium tuberculosis (MIC=5.2 nM), Bacillus cereus (MIC=1.56 μg/mL), and Plasmodium falciparum (IC50=2.19 μM), making it a valuable compound for research in cancer and infectious diseases.
  38. Anti-Bacterial Agent

    Lunatoic acid B is an anti-bacterial agent that exhibits significant bacterial inhibitory activity. Additionally, it demonstrates partial anti-mould properties, making it useful in studies exploring microbial resistance and infection control. This compound is applicable in various research contexts, including the development of novel antibacterial formulations and understanding mechanisms of microbial growth inhibition.
  39. Anti-Bacterial Agent

    Juvenimicin A2 is an antibacterial agent that primarily targets a range of bacteria. It has demonstrated efficacy against Gram-positive bacteria and select strains of Gram-negative bacteria. This compound is utilized in research applications aimed at understanding bacterial resistance mechanisms and developing new antimicrobial therapies.
  40. Antibacterial Agent

    Axinysone B functions as a potent antibacterial agent, isolated from the marine alga Laurencia similis. It exhibits significant activity against Staphylococcus species, making it a valuable compound for studies focused on antibacterial properties and microbial resistance. This reagent is suitable for research applications aimed at understanding bacterial infections and exploring novel antibacterial treatments.
  41. Antibacterial Agent

    Arizonin B2 is a microbial metabolite that functions as an antibacterial agent, primarily targeting Gram-positive bacteria. Its effectiveness against these pathogens makes it a valuable tool for research into antibacterial treatments and mechanisms of resistance. A potential candidate for studies involving the development of new antibiotics, Arizonin B2 contributes to the understanding of microbial interactions and infections.
  42. Antibacterial Peptoid

    CHIR-29498 is an antibacterial peptoid that exhibits activity against both Gram-positive and Gram-negative bacteria. This compound is particularly useful in the investigation of pathogenic strains such as Staphylococcus aureus. CHIR-29498 serves as a valuable tool for research focused on bacterial infections and the development of novel antimicrobial therapies.
  43. Anti-Bacterial Agent

    Olivomycin A is an antibiotic with potent activity against Gram-positive bacteria, demonstrating significant effectiveness in inhibiting bacterial growth. Its mechanism of action involves interference with nucleic acid synthesis, making it a valuable tool in microbiological research. Olivomycin A is particularly useful for studying bacterial resistance mechanisms and the development of new antimicrobial therapies.
  44. Antifungal Agents

    Bensuldazic acid is a lipophilic 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione (THTT) derivative functioning as an antifungal agent. It exhibits significant antifungal activity, making it a valuable compound for research in fungal infections. Bensuldazic acid can also serve as a prodrug model, facilitating studies in drug development and fungal pathogenesis.
  45. Anti-Bacterial Agent

    Rhodomycin B is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits significant antibacterial activity while demonstrating a weaker effect against Gram-negative bacteria and fungi. Rhodomycin B serves as a valuable reagent in research focusing on bacterial infections and antibiotic resistance mechanisms.
  46. Antimicrobial Agent

    9,12,13-Trihydroxy-10-octadecenoic acid acts primarily as an antimicrobial agent. This compound exhibits significant antibacterial and antifungal properties, making it valuable for various biological research applications. It is particularly useful in studies focused on infection control and the development of novel antimicrobial therapies.
  47. Anti-Bacterial Agent

    Midecamycin A4 is a macrolide antibiotic primarily targeting Gram-positive bacteria, exhibiting potent antibacterial activity. It demonstrates limited effectiveness against Gram-negative bacteria, mycobacteria, and fungi. This compound is valuable in research focused on antibiotic resistance and the development of novel antimicrobial agents.
  48. Anti-Bacterial Agent

    Formadicin B is an anti-bacterial agent that exhibits potent activity against various strains of Pseudomonas, Proteobacteria, and alkaline-producing bacilli. This compound is valuable in research focused on bacterial infections and the development of new antimicrobial therapies. Its efficacy against multi-drug resistant bacteria makes it a significant candidate for further investigation in the field of microbiology.
  49. Antibacterial Agent

    Broquinaldol is a brominated quinoline that serves as a potent antibacterial agent specifically effective against Staphylococcus species. In addition to its antimicrobial properties, Broquinaldol acts as a Mn(II) ionophore, facilitating the synthesis of metalloantibiotics. This compound is valuable in research focused on developing novel antibacterial therapies and understanding metal ion interactions in biological systems.
  50. Antibacterial Agent

    Trospectomycin is a broad-spectrum antibacterial agent that targets bacterial protein synthesis by inhibiting ribosomal function. This compound is especially relevant in the study of resistant bacterial strains and can be utilized in research focusing on antibiotic efficacy and mechanisms of resistance. Its structural similarity to Spectinomycin allows for exploration of its unique pharmacological properties and potential therapeutic applications in infectious disease research.

Items 4051-4100 of 4946

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