Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
Cuevaene A is an antibacterial agent with demonstrated activity against Gram-positive bacteria, notably Bacillus subtilis (ATCC 11060). Additionally, it exhibits modest antifungal properties against various fungal strains, including Fusarium verticillioides (S68) and Rhizoctonia solani (GXE4). This compound is useful for research applications aimed at investigating antibacterial and antifungal mechanisms, as well as exploring potential therapeutic options in microbial infections. -
Antibacterial Agent
Antifungal agent 85 (compound 24f) functions as a potent antibacterial agent, demonstrating minimum inhibitory concentration (MIC) values ranging from 2.5 to 10 μM against a variety of Gram-positive bacteria. This compound is valuable for research applications focusing on bacterial infections and the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Bagremycin B is an antibacterial agent derived from the Streptomyces sp. Tu 4128 strain. It exhibits weak activity against Gram-positive bacteria, as well as the fungi Saccharomyces cerevisiae and Candida albicans. This compound is primarily utilized in research applications focusing on the inhibition of bacterial and fungal growth, contributing to the understanding of antimicrobial mechanisms and the development of new therapeutic agents. -
Antibacterial Agent
Antibacterial agent 229 is a potent antibacterial compound that targets bacterial membranes and DNA. It exhibits significant antibacterial and antifungal activity by disrupting the integrity of bacterial membranes and intercalating into DNA structures. Furthermore, it inhibits topoisomerase IV with an IC50 value of 10.88 µM, making it a valuable tool for research applications in microbiology and drug development. -
Antibacterial Agent
N,O-Diacetyltyramine is an antibacterial agent that exhibits cytotoxic properties. It is derived from the actinomycete Pseudonocardia endophytica VUK-10 and demonstrates activity against both Gram-positive and Gram-negative bacteria, as well as fungi. Additionally, N,O-Diacetyltyramine has been shown to be cytotoxic to various cancer cell lines, including MDA-MB-231, HeLa, MCF-7, and OAW-42, making it a promising candidate for research in antimicrobial and anticancer applications. -
Antibacterial Agent
Aurachin C is an isoprenoid quinoline alkaloid that functions primarily as a selective inhibitor of terminal oxidases. It exhibits significant antibacterial, antiplasmodial, and antifungal properties, making it a valuable compound for research in infectious disease models. Its mechanism of action and broad-spectrum activity render Aurachin C a useful tool for investigating microbial resistance and developing new antimicrobial therapies. -
Anti-Bacterial Agent
Bagremycin A is an anti-bacterial agent derived from the Streptomyces sp. Tu 4128 strain. It exhibits modest activity against Gram-positive bacteria, as well as the yeast Saccharomyces cerevisiae and the pathogenic fungus Candida albicans. This reagent is utilized in research applications aimed at exploring bacterial resistance mechanisms and the development of novel antimicrobial strategies. -
Antibacterial Agent
1-Methyl-4-nitroimidazole is an antibacterial agent that functions primarily through reduction by bacterial nitroreductases, leading to the generation of toxic derivatives. These derivatives induce DNA damage and inhibit bacterial nucleic acid synthesis, while also producing toxic superoxides that promote bacterial cell death. This compound demonstrates moderate in vitro activity against both bacterial and fungal pathogens and is applicable in research focused on skin infections, purulent infections, and urinary tract infections. -
Antibacterial Agent
Cuevaene B is an antibacterial agent isolated from the gdmAI-disrupted strain of Streptomyces sp. LZ35. It exhibits moderate activity against Gram-positive bacteria, such as Bacillus subtilis, and demonstrates modest antifungal properties against fungi including Fusarium verticillioides and Rhizoctonia solani. This compound is applicable in studies investigating bacterial and fungal inhibition, contributing to the development of novel antimicrobial agents. -
Antibacterial Agent
Rugulosin is a crystalline compound derived from Penicillium rugulosum, exhibiting potent antibacterial properties. This agent demonstrates selective activity against a variety of bacterial strains while also displaying moderate antifungal effects. Its unique biological activity makes Rugulosin a valuable tool for research in microbial biology and the development of new antibacterial therapies. -
Antibacterial/Fungicidal Agent
Sepiumol A is a polyphenolic compound derived from the bark of Periploca sepium Bunge, functioning as an antibacterial and antifungal agent. This compound demonstrates notable biological activity against various bacterial and fungal strains, making it a valuable resource in microbiological research. Additionally, Sepiumol A has potential applications in the formulation of e-cigarette liquids, where it may help mitigate undesirable sweetness and greasiness while enhancing microbial safety. -
Bacterial Metabolite
(–)-Mycousnine is a microbial metabolite and derivative of Usnic Acid, with notable antibacterial and antifungal properties. It demonstrates activity against Gram-positive bacteria, including Bacillus subtilis, Kocuria rhizophila, and Staphylococcus aureus, with minimum inhibitory concentrations (MICs) of 4, 8, and 4 µg/mL, respectively. In contrast, it exhibits limited effectiveness against Gram-negative bacteria such as Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. Additionally, (–)-Mycousnine is effective against fungi, including Trichophyton mentagrophytes, Trichophyton rubrum, and Candida albicans, with MICs of 25, 25, and 100 µg/mL, respectively. This compound is suitable for research in antimicrobial drug development and fungal infection studies. -
Antibacterial Drug
Antibacterial agent 129 is an oxetanyl-quinoline derivative that exhibits potent antibacterial activity targeting Pseudomonas mirabilis and Bacillus subtilis, with minimum inhibitory concentrations (MICs) of 31.25 μM and 31.5 μM, respectively. Additionally, it demonstrates significant antifungal activity against Aspergillus niger, also with an MIC of 31.25 μM. Notably, Antibacterial agent 129 displays excellent antimycobacterial properties, with an MIC of 57.73 μM against Mycobacterium tuberculosis H37Rv. This compound can be utilized in pharmaceutical research to explore new antibacterial and antifungal therapies. -
Antibacterial Agent
8-Acetyl-7-hydroxycoumarin is a coumarin derivative that exhibits significant antibacterial and antifungal activities. This compound targets bacterial cell membranes, disrupting their integrity and leading to cell death. It is valuable for research in the development of novel antimicrobial agents and studying microbial resistance mechanisms. -
Antibacterial Agent
A-26771B is an antibacterial agent derived from Penicillium turbatum. It demonstrates moderate antimicrobial activity against Gram-positive bacteria, mycoplasma, and fungi. Additionally, A-26771B inhibits potassium-dependent ATPase in rat liver mitochondria, making it useful for research applications focused on microbial resistance and mitochondrial function. -
Antibacterial Agent
Isodihydroauroglaucin is a fungal metabolite that acts as an antibacterial agent. It exhibits significant antibacterial activity, making it a valuable tool in the study of microbial infections and antibiotic resistance. Researchers can utilize Isodihydroauroglaucin to explore its potential applications in developing new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 232 (compound Y41) is a potent antibacterial compound that targets bacterial cell membranes. It exerts its biological activity by inducing cell peroxidation, leading to disruption of membrane integrity. This reagent is applicable in research exploring antibacterial mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Bacterial
Fenticonazole is an imidazole derivative that targets bacterial and fungal organisms. It exhibits significant antibacterial and antifungal activity, making it a valuable compound for the study of mixed vaginitis. This reagent is useful in exploring the efficacy of treatments against infections caused by both bacteria and fungi. -
Antimycobacterial Agent
Antituberculosis agent-6 is a potent antimycobacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant activity with a minimum inhibitory concentration (MIC) of 3.49 μM. Additionally, Antituberculosis agent-6 exhibits notable antifungal efficacy against Aspergillus niger, with an MIC of 62.50 μM. The compound also shows high gastrointestinal absorption, making it a valuable candidate for further research in tuberculosis and fungal infections. -
Bacterial/Fungal Inhibitor
Pyruvic acid semicarbazone is a bacterial and fungal inhibitor. This compound demonstrates significant biological activity against various microbial strains, making it a valuable tool for investigating anti-infective agents. Additionally, pyruvic acid semicarbazone has potential applications in cancer research and plant growth regulation studies. -
Antibacterial Agent
NK 1971 is an antibacterial agent that exhibits promising antifungal activity. This compound has been studied for its effects on microbial infections and may impact neurological functions, potentially leading to decreased motor skills and seizures in animal models. Its diverse biological activity makes it a valuable tool for research in microbial pathogenesis and therapeutic interventions. -
Antibacterial Agent
RMG8-8 is an antibacterial agent with demonstrated efficacy against Cryptococcus neoformans, exhibiting an IC50 of 1.56 μg/mL. This compound is valuable for research focused on fungal infections and therapeutic development. Its potent activity provides a useful tool for screening and evaluating new antifungal strategies. -
Anticancer/antibacterial Agent
Antioxidant/anticancer agent 1 is a pyrimidine-derivatized Schiff base derived from pyrimidine hydroxy-1-naphthaldehyde, targeting multiple biological pathways. This compound exhibits significant antibacterial, antioxidant, antifungal, and anticancer activities, making it a valuable reagent for diverse research applications. Its multifaceted biological properties position it as a candidate for further investigation in cancer and infectious disease studies. -
Anti-bacterial Agent
(±)-Lomatin, a coumarin-type secondary metabolite derived from Coleonema album, exhibits significant antibacterial activity. It is primarily researched for its efficacy against bacterial, mycobacterial, and fungal infections. This compound serves as a valuable tool in investigating microbial pathogenesis and the development of novel antimicrobial therapies. -
Antibacterial Agent
Bacimethrin (NSC 66577) is an antibacterial agent that acts as an antagonist of thiamin biosynthesis. This compound effectively inhibits the growth of various bacteria and yeast, making it a valuable tool in microbiological research. Its application extends to studies investigating bacterial resistance mechanisms and the development of new antibacterial therapies. -
Antimycobacterial Drug
Antituberculosis agent-7 is an oxetanyl-quinoline derivative primarily targeting mycobacterial infections. It exhibits potent antimycobacterial activity, demonstrating a minimum inhibitory concentration (MIC) of 3.41 μM against Mycobacterium tuberculosis H37Rv. Additionally, it displays notable antibacterial effects against Proteus mirabilis with an MIC of 31.25 μM and antifungal activity against Aspergillus niger with an MIC of 62.5 μM. This compound holds potential for research in antimicrobial susceptibility and drug development against various infectious diseases. -
Antibacterial Peptide
Metchnikowin is an antibacterial peptide derived from fruit flies, exhibiting potent antimicrobial properties against both bacteria and fungi. Its activity is regulated through the TOLL and IMD signaling pathways, making it a valuable tool for studying immune responses in various infectious conditions. This peptide is widely utilized in research focused on host defense mechanisms and the development of novel antimicrobial agents. -
Anti-bacterial Peptide
Pseudin-2 is an antimicrobial peptide derived from the skin of the South American paradoxical frog, Pseudis paradoxa. It exhibits potent growth inhibition against Gram-negative bacteria, making it a valuable tool for antibacterial research. Pseudin-2 may be utilized in studies aimed at understanding antimicrobial mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
PK-10 is a synergistic antibacterial agent that combines the active components of Fluconazole, exhibiting potent antifungal activity against various strains of Fluconazole-resistant Candida albicans. This compound effectively inhibits hyphae formation and induces the accumulation of reactive oxygen species, leading to mitochondrial dysfunction. Additionally, PK-10 disrupts mitochondrial membrane potential and decreases intracellular ATP levels, highlighting its potential applications in antifungal research and therapeutic development. -
Antibacterial Compound
Di-O-methylhonokiol is a natural phenolic compound with notable antibacterial properties. It exhibits significant activity against Gram-positive bacteria, acid-fast bacilli, and various yeast and filamentous fungi. This compound is valuable for research applications focused on fungal infections and the development of antibacterial agents. -
Antibacterial Agent
(±)9-HpODE is a long-chain lipid hydroperoxide derived from the peroxidation of linoleic acid. This compound can induce the oxidation of intracellular glutathione (GSH), leading to alterations in cellular redox state. Additionally, (±)9-HpODE demonstrates antibacterial and antifungal activity, making it a valuable reagent for research into microbial pathogenesis and oxidative stress responses. -
Antibacterial Agent
4-Methylbenzohydrazide is an antibacterial agent that exerts its activity against a range of microbial targets. It demonstrates a potent minimum inhibitory concentration (pMIC) value of 1.38 against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Aspergillus niger. This compound is suitable for research applications focused on developing antibacterial therapies and studying microbial resistance mechanisms. -
Antibacterial Agents
Benzoic acid lithium is an aromatic compound utilized primarily for its antibacterial properties. It effectively inhibits the growth of bacteria and fungi, making it a valuable preservative in various applications, including food, beverages, and cosmetics. This compound is widely used in research to study antimicrobial mechanisms and develop new preservative formulations. -
Antibacterial Agent
Deacylketoconazole is an orally active metabolite of ketoconazole, primarily functioning as an antibacterial agent. This compound demonstrates notable antifungal and antibacterial activities, making it relevant in the study of infectious diseases. Additionally, deacylketoconazole exhibits cytotoxic effects in rat hepatocytes, providing insights into its potential impact on liver function. It serves as a valuable tool in research focused on antimicrobial efficacy and cellular toxicity. -
Bacterial Inhibitor
N-Butanoyl-L-homoserine lactone (C4-HSL) is a bacterial inhibitor that functions as a signaling molecule in quorum sensing. This compound demonstrates significant antibacterial activity and effectively disrupts biofilm formation, particularly in Pseudomonas aeruginosa. Research applications include studying bacterial communication and developing strategies to combat antibiotic-resistant infections through targeted inhibition of quorum sensing pathways. -
Bacterial Inhibitor
2-Ethyl-6-methylphenol is an alkylphenol with significant antibacterial properties. This compound has demonstrated efficacy in inhibiting bacterial growth and exhibits potential insecticidal activity, making it a valuable tool in microbiological research and pest control studies. Its role as a bacterial inhibitor can facilitate investigations into microbial resistance and the development of novel antimicrobial agents. -
Antibacterial Agent
4-Chloro-2-methylphenol is an antibacterial agent that effectively inhibits bacterial growth through disruption of cell membrane integrity. Its broad-spectrum antimicrobial activity makes it suitable for use in various pharmaceutical applications, particularly as a preservative and excipient in formulations. This compound is also valuable in research settings focused on studying antibacterial mechanisms and developing new antimicrobial therapies. -
Anti-bacterial Agent
Perillene is a natural compound derived from essential oils, primarily recognized for its antibacterial properties. It exhibits significant antibacterial activity against various pathogens, making it a valuable reagent for research in microbial inhibition and infection prevention. Additionally, perillene has been investigated for its potential antitumor effects, contributing to studies focused on cancer therapeutics and natural product research. -
Antibacterial agent
Gypsogenic acid is a triterpenoid acid with established antibacterial properties, primarily targeting oral bacterial pathogens. It has demonstrated effective minimum inhibitory concentration (MIC) values ranging from 50 to 200 μg/mL against Enterococcus faecalis, Streptococcus salivarius, Streptococcus haematococcus, Streptococcus mutans, and Streptococcus sobrinus. Additionally, Gypsogenic acid has been shown to induce blood cortisone cleavage in isolated mice, with an IC50 of 56.6 μM, making it a promising candidate for further research in antibacterial and trypanoidal applications. -
Antibacterial Agent
Antibacterial agent 265 is a potent antibacterial compound targeting various bacterial strains. It exhibits significant activity against both gram-positive organisms such as Staphylococcus aureus, Micrococcus luteus, and Bacillus subtilis, as well as gram-negative bacteria including Escherichia coli, Pseudomonas aeruginosa, and Flavobacterium devorans. This compound is valuable for research applications related to infection control, antimicrobial resistance, and the development of new antibacterial therapies. -
Bacterial Inhibitor
Upleganan is a polymyxin analogue that functions as a bacterial inhibitor, exhibiting antibiotic activity against multidrug-resistant Gram-negative pathogens. It demonstrates significant efficacy, with minimum inhibitory concentration (MIC) values of 0.125 mg/L against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301. Upleganan is valuable for research applications focusing on antibiotic resistance and the development of novel antibacterial therapies. -
Bacterial Inhibitor
Gepotidacin (S enantiomer) is a potent bacterial inhibitor that targets bacterial DNA replication and transcription processes. This compound exhibits effective antimicrobial activity against a range of gram-positive and gram-negative bacteria, making it valuable for research in infectious disease models. Its mechanism of action involves inhibition of bacterial topoisomerase, contributing to its bactericidal effects. Gepotidacin (S enantiomer) is primarily applied in studies focused on antibiotic resistance and the development of new therapeutic strategies. -
Bacterial Inhibitor
Griselimycin is a cyclic lipopeptide that functions as a bacterial inhibitor by specifically binding to the sliding clamp of bacterial DNA polymerase, while exhibiting no interaction with human proliferating cell nuclear antigen (PCNA). This compound demonstrates potent antibacterial activity against Mycobacterium tuberculosis, including drug-resistant strains, and various Gram-negative bacteria. Griselimycin is useful in research applications focused on bacterial DNA replication and the development of new antibacterial therapeutics. -
Antibacterial Drug
N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone is a member of the N-Acyl homoserine lactone (AHL) family derived from V. alginolyticus strains. This compound demonstrates significant antibacterial activity and plays a crucial role in biofilm formation. Its unique properties make it valuable for studying bacterial communication and quorum sensing mechanisms in various research applications. -
Antibacterial Agent
IPrAgCl is an antibacterial agent with demonstrated antiproliferative activity. It exhibits an IC50 of 30 nM against the MCF7 cell line and 35 nM against the KB cancer cell line. Additionally, IPrAgCl induces apoptosis in the HL60 cell line through the translocation of apoptosis-inducing factor from the mitochondria to the nucleus, making it a valuable tool for research in cancer and antibacterial studies. -
Antibacterial Agent
Macrocarpal A, a potent antibacterial agent derived from the leaves of Eucalyptus macrocarpa, exhibits significant antimicrobial activity. It effectively inhibits the growth of Bacillus subtilis PCI219 with a minimum inhibitory concentration (MIC) of below 0.2 µM, and Staphylococcus aureus FDA209P, with an MIC of 0.4 µM. This compound is valuable for research applications focused on antibacterial efficacy and the development of antimicrobial agents. -
Bacterial Inhibitor
Ganoderol A is a terpenoid derived from Ganoderma lucidum that acts as a bacterial inhibitor. It demonstrates antimicrobial properties and plays a role in inhibiting the cholesterol synthesis pathway. Additionally, Ganoderol A exhibits significant anti-inflammatory effects and provides protection against ultraviolet A (UVA) damage, making it valuable for research in microbial resistance and skin protection strategies. -
Antibacterial Agent
4-Heptyloxyphenol functions as an antibacterial agent, exhibiting significant activity against periodontal pathogens such as Porphyromonas gingivalis, Streptococcus artemidis, and Streptococcus sobrinus, with minimum inhibitory concentrations (MIC) of 0.10, 0.21, and 0.14 mM, respectively. This compound is useful in scientific research focused on oral microbiology and the development of novel antibacterial therapies targeting oral pathogens. -
Antibacterial Agent
Antibacterial Agent 26 is a potent antibacterial compound targeting a wide range of bacterial pathogens. With strong activity against both Gram-positive and Gram-negative bacteria, it is suitable for various research applications including studies on antimicrobial resistance and drug efficacy. This compound is valuable for researchers investigating novel antibacterial strategies and mechanisms of action. -
Bacterial Inhibitor
(5α)-Stigmastane-3,6-dione is a naturally occurring sterol with antibacterial properties. It functions by inhibiting bacterial growth, making it valuable for research in antimicrobial applications. Its isolation from Ailanthus altissima Swingle highlights its natural origins and potential utility in studies exploring microbial resistance and antibiotic development.
