Deacylketoconazole

Catalog No.: A28338
Antibacterial Agent
Deacylketoconazole is an orally active metabolite of ketoconazole, primarily functioning as an antibacterial agent. This compound demonstrates notable antifungal and antibacterial activities, making it relevant in the study of infectious diseases. Additionally, deacylketoconazole exhibits cytotoxic effects in rat hepatocytes, providing insights into its potential impact on liver function. It serves as a valuable tool in research focused on antimicrobial efficacy and cellular toxicity.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDeacylketoconazole is an orally active metabolite of ketoconazole, primarily functioning as an antibacterial agent. This compound demonstrates notable antifungal and antibacterial activities, making it relevant in the study of infectious diseases. Additionally, deacylketoconazole exhibits cytotoxic effects in rat hepatocytes, providing insights into its potential impact on liver function. It serves as a valuable tool in research focused on antimicrobial efficacy and cellular toxicity.
Product Information
Catalog NumA28338
FormulaC24H26Cl2N4O3
Molecular Weight489.39
CAS Number67914-61-8
SMILESClC1=CC=C(C(Cl)=C1)[C@@]2(OC[C@H](O2)COC3=CC=C(C=C3)N4CCNCC4)CN5C=CN=C5
SynonymsN-Deacetylketoconazole; R-39519
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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