Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Quorum sensing-IN-2 is a potent quorum sensing inhibitor that targets bacterial communication mechanisms to diminish pathogenicity while preserving overall bacterial growth. This compound effectively reduces bacterial infections with minimal hemolytic activity. Additionally, Quorum sensing-IN-2 exhibits a synergistic effect when combined with Ciprofloxacin in models of Pseudomonas aeruginosa PAO1 bacteremia, making it a valuable tool for investigating bacterial virulence and developing novel therapeutic strategies. -
Antibacterial Agent
Pachyaximine A is an alkaloid derived from the root of Sarcococca hookeriana, primarily recognized for its antibacterial properties. This compound exhibits significant activity against bacterial strains, making it a valuable tool for research focused on combating bacterial infections. Its unique mechanism of action and natural origin position Pachyaximine A as an important candidate in the development of novel antibacterial agents. -
Antibacterial Agent
Antibacterial Agent 77 primarily targets bacterial cell growth. This compound exhibits significant antibacterial activity, making it suitable for research applications aimed at investigating bacterial infections and developing new antimicrobial therapies. Its effectiveness against various bacterial strains can provide insights into mechanisms of resistance and the potential for therapeutic interventions. -
Antibacterial/Anticancer Agent
AJI-9561 is a benzoxazole derivative that functions as an antibacterial and anticancer agent. This compound demonstrates significant cytotoxic effects, inhibiting the proliferation of Jurkat T cells and mouse P388 leukemia cells, with IC50 values of 0.88 µM and 1.63 µM, respectively. AJI-9561 is suitable for research focused on exploring its potential therapeutic applications in oncology and infectious diseases. -
Antibacterial Agent
Sperabillin A is an antibacterial agent that exhibits activity against both gram-positive and gram-negative bacteria. In addition to its antibacterial properties, Sperabillin A demonstrates significant inhibition of human umbilical vein endothelial (HUVE) cell proliferation. Notably, it also displays anti-tumor activity against B16 melanoma in mouse models, making it a valuable compound for studying bacterial infections as well as cancer biology. -
Anti-bacterial Agent
(-)-Decursinol is a natural pyranocoumarin compound derived from the roots of Apiaceae plants, such as Ferulago campestris. This compound exhibits potent antibacterial activity, effectively inhibiting both Gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis, and Gram-negative bacteria such as Salmonella typhii and Enterobacter species, with minimum inhibitory concentrations ranging from 16 to 64 μg/mL. Additionally, (-)-Decursinol demonstrates antioxidant properties, making it valuable for research applications focused on bacterial infections and oxidative stress. -
Anti-bacterial Agent
Almurtide (nor-MDP) is a muramyl dipeptide derivative functioning as an anti-bacterial agent. It exhibits significant anti-inflammatory and anti-tumor properties, alongside protective effects against infections caused by Pseudomonas aeruginosa and Candida albicans in murine models. Additionally, Almurtide demonstrates inhibitory effects on the carcinogenic Friend leukemia virus, making it relevant for cancer research and infectious disease studies. -
Bacterial
N-Heptanoyl-L-homoserine lactone is an N-acyl-homoserine lactone that targets the quorum sensing mechanisms of gram-negative bacteria. This compound is involved in the regulation of gene expression, facilitating communication between bacterial cells. It is primarily utilized in research applications focused on bacterial pathogenesis and biofilm formation, providing insights into microbial behavior and interactions. -
Antibacterial Peptide
Hc-CATH is an antibacterial peptide derived from sea snake cathelicidin, exhibiting broad-spectrum antimicrobial activity. It effectively inhibits the growth of Shigella dysenteriae and Klebsiella pneumoniae, with minimum inhibitory concentrations (MIC) ranging from 0.16 mM to 20.67 mM. Additionally, Hc-CATH demonstrates anti-inflammatory properties, making it a valuable tool for research in the fields of infectious disease and inflammation. -
Antibacterial Agent
CP-74667 is a quinolone antibacterial agent with potent activity against various bacterial strains. It exhibits significant inhibitory effects on Xanthomonas maltophilia with a MIC50 of 1 μg/mL, as well as Staphylococcus spp. (MIC50 = 0.06-0.12 μg/mL) and enterococci (MIC50 = 0.5-4 μg/mL). This compound is valuable for research applications targeting bacterial infections and assessing antibiotic efficacy. -
Bacterial Inhibitor
ORM-3819 is a bacterial inhibitor targeting Staphylococcus aureus. This compound exhibits broad-spectrum antimicrobial activity against both methicillin-susceptible (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). Additionally, ORM-3819 reduces the phagocytosis of MRSA and MSSA strains by monocytic THP-1 cells, making it valuable for research related to bacterial infections and resistance mechanisms. Its efficacy in combatting staphylococcal infections positions it as a critical tool in antimicrobial studies. -
Anti-Bacterial Agent
Roseorubicin B is an anti-bacterial agent with notable activity against Gram-positive bacteria and Mycobacterium species. Additionally, it exhibits inhibitory effects on leukemia L1210 cells, with an IC50 value of 0.06 μg/mL. This compound is valuable for research applications focusing on bacterial infections and cancer therapeutics. -
Bacterial Inhibitor
4-Glycidyloxycarbazole is an antimicrobial agent that targets bacterial biofilm formation. It exhibits significant inhibitory activity against various bacterial strains, making it a valuable tool for studying bacterial behavior and infection control. This compound is useful in research applications focused on biofilm-related challenges in microbiology and infectious disease. -
Antibacterial Agent
Delmopinol is an antibacterial agent that targets oral bacteria to inhibit the formation of dental biofilm. Its primary mechanism involves interference with microbial adhesion and biofilm development, making it a valuable reagent for research focused on oral health and hygiene. This compound is especially useful in studies investigating the prevention of dental plaque and associated diseases. -
Antibacterial Agent
Antibacterial Agent 194 is a potent antibacterial compound targeting Mycobacterium tuberculosis (Mtb). It exhibits significant antimicrobial activity with a minimum inhibitory concentration (MIC) of 1 μg/mL. This agent is valuable for research applications focused on combating tuberculosis and understanding the mechanisms of bacterial resistance. -
Antibacterial Agent
SCUT1-2 is a bifunctional antibacterial agent targeting Clostridium difficile. It demonstrates significant antibacterial activity, effectively killing vegetative cells with a minimum inhibitory concentration (MIC) of 0.06-0.50 μg/mL, while also inhibiting spore germination in vitro. In preclinical models, SCUT1-2 has shown efficacy in alleviating symptoms associated with C. difficile infection, including weight loss and diarrhea, and in preventing recurrent infections. -
Antibacterial agent
Anti-MRSA agent 16 is an inhibitor of methicillin-resistant Staphylococcus aureus (MRSA). This compound demonstrates potent antibacterial activity and shows enhanced efficacy when used in combination with oxacillin or meropenem in in vivo models, specifically in infected mice. It is a valuable tool for researchers investigating treatments for MRSA infections. -
Antibacterial Agent
BMY-28271 is an orally active cephalosporin that functions as a potent antibacterial agent. It exhibits a broad spectrum of activity against both gram-positive and gram-negative bacteria, making it a valuable compound for combating bacterial infections. Additionally, BMY-28271 demonstrates resistance to hydrolysis by various beta-lactamases, enhancing its efficacy in research applications focused on infection treatment and antibiotic resistance mechanisms. -
Bacterial Inhibitor
KSK120 is a potent bacterial inhibitor targeting Chlamydia trachomatis (C. trachomatis). It disrupts the developmental cycle of the bacteria, leading to a reduction in the infectivity of progeny by targeting the glucose-6-phosphate metabolic pathway. KSK120 is particularly relevant for research into antimicrobial strategies, as its mechanism may involve inhibition of transcriptional processes, offering a novel approach for the development of targeted therapies against C. trachomatis infections. -
Antibacterial Agent
c[Arg-Arg-Arg-Arg-Dip-Dip-Dip] is an antibacterial agent that demonstrates broad-spectrum activity against both drug-resistant Gram-positive and Gram-negative bacteria. It exhibits minimum inhibitory concentrations (MICs) of 3.1 μg/mL against MRSA (ATCC BAA-1556) and S. aureus (ATCC 29213), along with 12.5 μg/mL for P. aeruginosa (ATCC 27883) and E. coli (ATCC 25922). This compound is valuable for research applications focused on combating antibiotic resistance in pathogenic bacteria. -
Bacterial Inhibitor
10-Isobutyryloxy-8,9-epoxythymol isobutyrate is a bacterial inhibitor derived from Inula helenium and Inula royleana root cultures, exhibiting moderate antimicrobial activity. This compound demonstrates efficacy against various pathogens, including Staphylococcus aureus, Enterococcus faecalis, Candida albicans, and Pseudomonas aeruginosa, with MIC values of 50, 250, 250, 250, and 1000 μg/mL, respectively. It serves as a valuable tool for research in antibacterial studies and the exploration of potential therapeutic agents. -
Bacterial Inhibitor
LolCDE-IN-3 is an inhibitor targeting the LolCDE complex, which plays a critical role in bacterial lipid A transport. This compound exhibits potent antibacterial activity, making it a valuable tool for studying bacterial physiology and pathogen resistance mechanisms. It is suitable for research applications focused on antibiotic development and the exploration of novel antibacterial strategies. -
Bacterial Inhibitor
OV-1, sheep is an alpha-helical antimicrobial peptide derived from the SMAP29 peptide of sheep, specifically designed to target and inhibit a range of antibiotic-resistant bacterial strains. This compound demonstrates significant efficacy against both mucoid and nonmucoid strains of Pseudomonas aeruginosa. OV-1, sheep is a valuable tool for research applications focusing on antimicrobial resistance and the development of peptide-based therapeutics. -
Bacterial Inhibitor
GSK729 is a selective inhibitor of EchA6, a critical enzyme involved in the fatty acid biosynthesis pathway of Mycobacterium tuberculosis. By specifically targeting and inhibiting EchA6, GSK729 demonstrates significant bactericidal activity, effectively obstructing the growth of the bacterium. This compound is valuable for research applications focused on the development of new therapeutic strategies against tuberculosis and exploring the role of fatty acid synthesis in bacterial pathogenesis. -
Antibacterial/Antiparasitic Agent
Levofuraltadone is an antibacterial and antiparasitic agent primarily targeting Trypanosoma parasites. It exhibits significant anti-trypanosomiasis activity, making it a valuable tool in the study of human African trypanosomiasis. Additionally, Levofuraltadone can be utilized in researching various bacterial infections, contributing to the understanding of microbial pathogenesis and treatment strategies. -
Antibacterial Agent
Viscosin is a cyclic lipopeptide with potent antibacterial properties, targeting bacterial membranes and cell wall synthesis. It demonstrates significant efficacy against a range of Gram-positive bacteria, making it a valuable tool for investigating bacterial infections. Notably, Viscosin exhibits no antifungal activity. This compound serves as an essential reagent for research focused on bacterial pathogenesis and antimicrobial drug development. -
Antibacterial Agent
L-K6L9 is an antibacterial agent exhibiting notable antimicrobial and antibiofilm activities against Pseudomonas aeruginosa, particularly in isolates from cystic fibrosis patients. This compound demonstrates stability and resilience against degradation by sputum proteases commonly found in cystic fibrosis, while also minimizing the risk of inducing bacterial resistance. It serves as a valuable tool for research focused on developing novel therapeutic strategies for bacterial infections in cystic fibrosis. -
Antibacterial Activity
Moracin T is a natural compound isolated from the bark of mulberry trees, known for its antibacterial properties. It exhibits significant activity against a range of bacterial strains, making it a valuable candidate for research in antibiotic development and microbial resistance studies. Its efficacy in inhibiting bacterial growth positions Moracin T as a pertinent tool for investigating potential therapeutic applications in infectious diseases. -
Antibacterial Drug
Thalrugosaminine is a benzylisoquinoline alkaloid that exhibits antibacterial activity through its action on bacterial cell walls. It demonstrates effective antibacterial properties, with minimum inhibitory concentration (MIC) values ranging from 64 to 128 µg/ml. This compound is valuable in research focused on antibiotic development and understanding antibacterial mechanisms. -
Antibacterial Agent
Ianthelliformisamine B diTFA is a bromotyrosine-derived antibacterial agent that targets bacterial strains. It exhibits potent activity against Escherichia coli and Staphylococcus aureus, with minimum inhibitory concentrations (MICs) of 14.5 μM and 144.7 μM, respectively. This compound is valuable for research applications focused on antibacterial mechanisms and the development of new antimicrobial therapies. -
Antibacterial Agent
Lithooxazoline is a potent antibacterial agent that targets a range of bacterial strains. This compound exhibits significant antimicrobial activity, making it valuable for research in infectious diseases and antibiotic resistance. Its effectiveness in inhibiting bacterial growth positions it as a useful tool for investigating new antibacterial therapies. -
Antibacterial Agent
Olanexidine gluconate is an antibacterial agent with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. As an effective antiseptic, it demonstrates utility in the research of infection and inflammatory processes. Its diverse antimicrobial properties make it a valuable tool for studies focused on infection control and related therapeutic applications. -
Antimycobacterial Agents
B 746 is a clofazimine analog that targets Mycobacterium avium complex (MAC), exhibiting significant antimycobacterial activity. This compound is particularly noteworthy for its effectiveness in studies examining alternative treatment regimens for MAC infections. Its unique properties make it a valuable reagent in research focused on combating mycobacterial diseases. -
Anti-bacterial agent
S 3578 sulfate is a broad-spectrum antibacterial agent targeting various bacterial pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. With minimum inhibitory concentrations (MIC) of 0.78-3.13 μg/mL for MRSA and 1.56-6.25 μg/mL for Pseudomonas aeruginosa, S 3578 sulfate demonstrates potent antimicrobial activity. This compound is utilized in research related to infectious diseases, particularly in the study of antibiotic resistance and bacterial infections. -
Bacterial Inhibitor
NBTIs-IN-4 is a potent bacterial inhibitor targeting DNA gyrase and topoisomerase IV in Gram-positive pathogens. It exhibits significant antibacterial activity while maintaining a low frequency of resistance. This compound is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing new antibacterial therapies. -
Antibacterial Agent
Antibacterial Agent 141 (Compound B14) targets bacterial cell membranes and exhibits noteworthy antibacterial activity against four plant pathogens: Xanthomonas oryzae pv. oryzae (Xoo), Xanthomonas campestris pv. campestris (Xac), Pseudomonas syringae pv. actinidiae (Psa), and Clavibacter michiganensis subsp. michiganensis (Cmm), with an EC50 value of 1.28 μM. This compound effectively inhibits cell membrane formation and alters cell permeability, making it a valuable tool for research on plant pathogen control and resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 142 is an aromatic hydrazide that exhibits significant antibacterial activity. This compound functions as a bacteriostatic agent and is capable of inhibiting biofilm formation, making it valuable in studies focused on bacterial growth and infection control. Its properties support research into novel antibacterial therapies and the development of interventions against biofilm-associated infections. -
Bacterial Inhibitor
BPH-1358 free base is a potent inhibitor of human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS), exhibiting IC50 values of 1.8 μM and 110 nM, respectively. This compound demonstrates significant antibacterial activity against Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of approximately 250 ng/mL. BPH-1358 free base is suitable for research applications aimed at understanding bacterial resistance mechanisms and developing novel antibacterial strategies. -
Bacterial Inhibitor
Lankacidin C 8-acetate is an antibiotic that targets bacterial pathogens through its antibacterial activity. This compound, part of the Lankacidin antibiotic group, exhibits significant inhibitory effects against specific bacterial strains. Additionally, Lankacidin C 8-acetate can react with various acyl donors to generate ester derivatives, highlighting its relevance in antibiotic synthesis and development for research applications. -
Bacterial Inhibitor
Macranthoside A is a triterpene glycoside that acts as a bacterial inhibitor. It demonstrates significant antimicrobial activity, making it a useful compound for research applications aimed at studying bacterial infections and evaluating potential therapeutic agents against microbial resistance. -
Bacterial Inhibitor
I-A09 is a bacterial inhibitor that demonstrates significant antitubercular activity against Mycobacterium tuberculosis H37Rv. This compound and its derivatives, particularly the 1,2,3-triazole-adamantylacetamide hybrids synthesized via copper-catalyzed click chemistry, display enhanced efficacy with a minimum inhibitory concentration (MIC) as low as 3.12 μg/mL. These novel analogues, particularly N-(1-adamantan-1-yl)-2-(4-(phenanthren-2-yl)-1H-1,2,3-triazol-1-yl)acetamide (5t), have applications in research focused on tuberculosis treatment and the development of new antitubercular agents. -
Antibacterial Agent
Antibacterial Agent 76 functions by inhibiting bacterial cell wall synthesis, thereby exerting its antibacterial activity. This compound demonstrates effectiveness against a variety of Gram-positive and Gram-negative bacteria, making it suitable for research in antimicrobial resistance and the development of new antibacterial therapies. Antibacterial Agent 76 is ideal for studies focused on bacterial infections and the mechanisms of action of antibacterial compounds. -
Anti-Bacterial Agent
Paulomycin A is an anti-bacterial agent that demonstrates potent activity against Gram-positive bacteria. It effectively inhibits the growth of Staphylococcus aureus, including strains resistant to penicillin, streptomycin, neomycin, and macrolide antibiotics. This compound is valuable for research applications focused on antibiotic resistance and the development of new therapeutic strategies against bacterial infections. -
Bacterial Inhibitor
Antibacterial Agent 95 is a potent bacterial inhibitor with a primary target of Mycobacterium tuberculosis. Demonstrating a minimum inhibitory concentration (MIC) as low as 0.3 μM against the reference strain H37Rv, this 2-(quinoline-4-methoxy)acetamide compound effectively inhibits the growth of Mycobacterium tuberculosis in macrophage models of tuberculosis infection. Its exceptional activity makes it a valuable tool for research in antitubercular drug development. -
Antibacterial Agent
Obtusalin is a triterpenoid compound with identified antibacterial properties. Isolated from Rhaponticum dauricum, it exhibits UV absorption at 210 nm. This compound serves as a valuable tool in microbiological research to study bacterial inhibition and could potentially contribute to the development of new antibacterial agents. -
Antibacterial Agent
22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin is an antibacterial agent that targets Gram-positive pathogens (GPPs) and Mycoplasma pneumoniae. This pleuromutilin derivative exhibits potent antibacterial activity, making it suitable for research focused on combating infections caused by resistant bacterial strains. Its unique mechanism of action allows for exploration in various applications within antibiotic development and microbiological studies. -
Antibacterial agent
1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone functions as a potent antibacterial agent targeting Helicobacter pylori. It demonstrates notable antibacterial activity, with an MIC50 value of 22 µM and an MIC90 value of 50 µM against H. pylori Strain 51. This compound is valuable for research focused on the treatment of gastric and duodenal ulcers. -
Bacterial Inhibitor
Pelagiomicin A is a phenazine antibiotic with a primary mechanism targeting bacterial cell functions. This compound demonstrates significant antibacterial activity against both Gram-positive and Gram-negative bacteria, making it a valuable tool for research in microbial resistance. Additionally, Pelagiomicin A has shown promising antitumor effects in vitro and in vivo, underscoring its potential applications in cancer research. Its structure has been elucidated through a combination of spectroscopic data and synthesis techniques, contributing to the understanding of its biological properties. -
Antibacterial Agent
Antibacterial Agent 42 is a potent antibacterial compound that enhances the efficacy of Ceftazidime by significantly lowering its minimum inhibitory concentration (MIC). This agent exhibits strong activity against a range of bacterial pathogens, making it valuable in the development of combination therapies. Its applications extend to research focusing on antibiotic resistance and the optimization of existing antibacterial treatments. -
Anti-bacterial Agent
Macatrichocarpin A is a flavanone exhibiting notable anti-bacterial activity. It demonstrates inhibitory effects against Bacillus subtilis, with a minimum inhibitory concentration (MIC) of 26.5 μM. This compound can be isolated from the leaves of Macaranga trichocarpa, making it a valuable candidate for research into antimicrobial agents.
