Bacterial

Items 1251-1300 of 1393

Page
per page
Set Descending Direction
Catalog No.
Product Name
Application
Product Information
Citations
  1. Antibacterial Agent

    Decarboxy ciprofloxacin is an antibacterial agent primarily targeting bacterial pathogens. It exhibits significant antibacterial activity against various strains, including Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Bacillus subtilis, Enterobacter cloacae, Serratia marcescens, and shows particularly strong efficacy against Escherichia coli. This compound is valuable for research in the development of new antibacterial therapies and understanding antibiotic resistance mechanisms.
  2. Antibacterial Agent

    Antibacterial Agent 78 is a potent antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant activity against a variety of gram-positive and gram-negative bacteria, making it a valuable tool for investigating bacterial resistance mechanisms. This compound is suitable for research applications related to antibiotic development and microbiological studies.
  3. Antibacterial Agent

    Antibacterial Agent 131 is a quinoline derivative that targets bacterial cell integrity. It exerts antimicrobial activity by inhibiting ergosterol production, leading to disruption of fungal cell membranes. This compound is suitable for research applications focused on evaluating antibacterial and antifungal activities, contributing to the development of new antimicrobial therapies.
  4. Antibacterial Agent

    Antibacterial Agent 262 is a potent inhibitor of Xanthomonas oryzae pv oryzae, targeting bacterial growth and biofilm formation. This compound disrupts the integrity of bacterial cell membranes, leading to impaired viability and enhanced susceptibility to treatment. It is valuable for research applications focusing on bacterial pathogenicity, biofilm dynamics, and the development of novel antibacterial strategies.
  5. Antimycobacterial Agent

    Antimycobacterial Agent-3 is an effective antimycobacterial compound targeting Mycobacterium tuberculosis (MTB), demonstrating activity against both sensitive strain H37Rv and drug-resistant clinical isolates, with a minimum inhibitory concentration (MIC) ranging from < 0.029 to 0.110 μM. This agent exhibits low cytotoxicity in cell-based assays, making it a valuable tool for research into tuberculosis treatment and resistance mechanisms.
  6. Antibacterial Agent

    Antibacterial agent 278 (compound B1) is a potent antibacterial compound targeting Gram-positive bacteria. It demonstrates significant bactericidal activity, making it a valuable tool for research in the development of new antibacterial therapies. This agent is useful in studying mechanisms of bacterial resistance and evaluating antimicrobial efficacy.
  7. Antibacterial Agent

    Furaltadone L-tartrate is a nitrofuran antibacterial agent primarily used in the study of infections, particularly in chickens infected with Salmonella enteritidis. This compound exhibits both inhibitory and bactericidal effects against Staphylococci in vitro. Its applications extend to various research contexts involving bacterial infections and treatment efficacy assessment.
  8. Antibacterial Agent

    NLCQ-1 (NSC 709257) is an orally active antibacterial agent that specifically targets dormant Mycobacterium tuberculosis. This compound exhibits significant potential for research into tuberculosis treatment, particularly in addressing latent infections. Its ability to act on dormant bacteria makes it a valuable tool in the study of mycobacterial resistance and the development of novel therapeutic strategies.
  9. Antibacterial Agent

    LY 215890 is an orally active antibacterial agent targeting Escherichia coli EC14 and Klebsiella pneumoniae X26. This compound demonstrates effective antibacterial activity, making it suitable for research applications aimed at studying bacterial infections and resistance mechanisms. Its efficacy in selective bacterial inhibition supports investigations into novel therapeutic strategies in infectious disease management.
  10. Bacterial Inhibitor

    2'-Hydroxy-2-methoxychalcone acts as a bacterial inhibitor, demonstrating significant antimicrobial activity against various bacterial strains. This synthetic chalcone derivative is valuable for research in understanding bacterial resistance mechanisms and developing new antimicrobial agents. Its structural properties facilitate the exploration of structure-activity relationships in the field of medicinal chemistry.
  11. Antibacterial Agent

    Cefcanel is an orally active cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits effective antibacterial activity against methicillin-susceptible strains of Staphylococcus aureus and Staphylococcus epidermidis, as well as Haemophilus influenzae and Moraxella catarrhalis. Cefcanel serves as a substrate for hydrolysis by various beta-lactamases, including TEM-1, TEM-3, and Moraxella Bro-1, making it a valuable tool for research on antibiotic resistance mechanisms and bacterial susceptibility testing.
  12. Antibacterial Agent

    Antibacterial Agent 123 is a potent membrane-disrupting compound that targets antibiotic-resistant Gram-positive bacteria. This reagent demonstrates significant antibacterial activity, making it a valuable tool for research focused on developing novel therapeutic strategies against multi-drug resistant infections. Its ability to disrupt bacterial membranes positions it as an important candidate for studies aimed at understanding bacterial resistance mechanisms and evaluating new antibacterial therapies.
  13. Bacterial Inhibitor

    Chinfloxacin is a bacterial inhibitor that exerts antibacterial activity against a range of clinical isolates in vitro. Demonstrating a concentration-dependent bactericidal effect, Chinfloxacin shares antibacterial efficacy comparable to that of moxifloxacin. This compound is suitable for research applications focused on bacterial pathogenicity and the development of new antimicrobial agents.
  14. Bacterial Inhibitor

    Phenethicillin potassium is a β-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins. It demonstrates significant antibacterial activity against a range of Gram-positive bacteria, making it valuable in research applications focused on antimicrobial resistance and the mechanistic understanding of bacterial susceptibility. Its characteristic action profile facilitates studies in microbiology and pharmacology, providing insights into antibiotic efficacy and resistance mechanisms.
  15. Antibacterial Agent

    Antibacterial Agent 58 functions as an antibacterial agent, exhibiting a significant reduction in the minimum inhibitory concentration (MIC) of Ceftazidime. This compound enhances the efficacy of existing antibiotics, making it a valuable tool for researchers studying antibiotic resistance and developing combination therapies. Its biological activity is pivotal for investigations into bacterial infections and the optimization of antibacterial strategies.
  16. Bacterial Inhibitor

    Hikizimycin is a potent antibacterial agent that targets bacterial cell growth and division. This natural product exhibits significant antibacterial activity, making it a valuable tool for research focused on bacterial infections and their treatment. Its unique mechanism of action offers insights into new therapeutic strategies for combating antibiotic resistance.
  17. Bacterial Inhibitor

    Antibacterial Agent 28 is a bacterial inhibitor with a mechanism targeting the growth and proliferation of pathogens such as Methicillin-resistant Staphylococcus aureus (MRSA). It exhibits antimicrobial activity with minimum inhibitory concentrations (MICs) ranging from 0.5 to 2 μg/mL. This reagent holds promise for research applications aimed at developing new treatments against resistant bacterial infections.
  18. Antibacterial Agent

    Antibacterial Agent 55 is a potent antibacterial compound with demonstrated efficacy against a wide range of bacterial strains. This agent operates by disrupting vital cellular processes, leading to the inhibition of bacterial growth and replication. It is suitable for various research applications, including the study of bacterial resistance mechanisms and the development of novel antimicrobial therapies.
  19. Antibacterial Agent

    ABT-255 hydrochloride is an orally active antibacterial agent targeting Mycobacterium tuberculosis. It demonstrates potent in vitro activity with a minimum inhibitory concentration (MIC) ranging from 0.016 to 0.031 μg/mL against both drug-susceptible and resistant strains, including those resistant to Rifampin and Ethambutol. Additionally, ABT-255 hydrochloride exhibits efficacy against Gram-positive and Gram-negative bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli, effectively reducing viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mice. This compound is valuable for research applications focused on pulmonary tuberculosis.
  20. Antibacterial Agent

    Ceftizoxime alapivoxil is an orally active prodrug of Ceftizoxime, functioning primarily as an antibacterial agent. It exhibits potent inhibitory activity against both gram-positive and gram-negative bacteria, making it a valuable tool in the study of bacterial infections. This compound is suitable for research applications focused on developing strategies for combating bacterial pathogenicity.
  21. Antibacterial Agent

    Antibacterial Agent 158, a Micrococcin analogue, functions primarily by targeting bacterial protein synthesis. This compound exhibits significant activity against impetigo and Clostridioides difficile infections (CDI), making it valuable for research in bacterial pathogenesis and antibiotic resistance. Its efficacy in combating specific bacterial strains supports its application in the development of new antibacterial therapies.
  22. Antibacterial Agent

    Antitubercular agent-37 is an antibacterial agent with specific activity against Mycobacterium species. It demonstrates significant antimycobacterial efficacy, exhibiting a minimum inhibitory concentration (MIC) of 0.16 μg/mL. This compound is valuable for research applications focused on tuberculosis and the development of novel antitubercular therapies.
  23. Anti-Bacterial Agent

    Gentamicin C2a is an aminoglycoside antibiotic that targets bacterial ribosomes, inhibiting protein synthesis. It demonstrates significant antimicrobial activity against a wide range of Gram-negative and some Gram-positive bacteria. This reagent is primarily utilized in microbiological research and clinical applications to study bacterial infections and antibiotic resistance mechanisms.
  24. Bacterial Inhibitor

    β-L-Gulopyranosyl-caldarchaetidyl-glycerol (GuCGp) is a polar lipid compound targeting bacterial membranes. Its role in the lipid composition of thermoacidophilic bacteria is crucial for understanding bacterial adaptation to varying environmental conditions. This compound is valuable for research applications focused on microbial physiology and membrane biochemistry.
  25. Antibacterial Agent

    23-O-Demycinosyltylosin is an acyl derivative that functions as a potent antibacterial agent. It exhibits significant activity against a range of bacterial strains, making it a valuable tool for research focused on antimicrobial resistance and infection control. Its unique mechanism of action allows for the exploration of bacterial cell wall synthesis and potential therapeutic applications in infectious disease management.
  26. Antibacterial Agent

    Antibacterial Agent 122 is a thiourea derivative that primarily targets mycobacterial infections. This compound exhibits significant anti-mycobacterial activity while demonstrating low cytotoxicity, making it a valuable tool for tuberculosis research. Researchers can utilize Antibacterial Agent 122 to explore mechanisms of action and potential therapeutic applications in combating mycobacterial diseases.
  27. Antibacterial Agent

    Isoaltenuene is an antibacterial agent that exhibits moderate activity against Staphylococcus aureus. This compound can be isolated from the fungus Alternaria alternata cib-137 and serves as a valuable resource for research into bacterial infections and potential therapeutic applications. Its unique properties make it an important subject of study in the field of microbiology and drug development.
  28. Antibacterial Agent

    MmpL3-IN-2 is an inhibitor of the MmpL3 protein, a key component in the cell wall biosynthesis of Mycobacterium tuberculosis. This compound demonstrates low cytotoxicity and moderate metabolic stability, making it suitable for antibacterial research, particularly in the study of tuberculosis. Its selective activity against MmpL3 positions it as a promising candidate for the development of new therapeutic strategies targeting mycobacterial infections.
  29. Antibacterial/Anti-inflammatory Agent

    Farobin A is a natural compound that exhibits antibacterial and anti-inflammatory activities. It demonstrates efficacy against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478, making it a valuable agent for antibacterial research. Additionally, Farobin A has been shown to modulate inflammatory responses by reducing the levels of cytokines IL-6 and TNF-α, positioning it as a potential therapeutic target in inflammation-related studies.
  30. Antibacterial Agent

    Antibacterial Agent 56 is a potent antibacterial compound with demonstrated efficacy against a broad range of bacterial strains. Its primary mechanism involves inhibiting bacterial growth through disruption of cellular processes. This reagent is suitable for various research applications, including the study of bacterial resistance mechanisms and the development of novel antimicrobial therapies.
  31. Bacterial Inhibitor

    Ceratotoxin B is an antibacterial peptide derived from the sexually mature females of Ceratitis capitata. It exhibits lytic and antibacterial activity, making it a valuable research tool for studying bacterial inhibition and antimicrobial mechanisms. This peptide can be utilized in studies aimed at understanding bacterial resistance and the development of novel antibacterial agents.
  32. Bacterial Inhibitor

    TP0586352 is a potent LpxC inhibitor specifically designed to target bacterial pathogens, including carbapenem-resistant Klebsiella pneumoniae. This compound exhibits significant antibacterial activity while maintaining a favorable safety profile, as it does not pose cardiovascular risks. Additionally, TP0586352 features an alkyne functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions for further chemical modifications.
  33. Antimycobacterial Agent

    Antimycobacterial agent-2 is a potent antimycobacterial compound that targets Mycobacterium tuberculosis (M.tb) H37Rv. It demonstrates significant anti-mycobacterial activity, with a minimum inhibitory concentration (MIC99) of 0.8 µM. Additionally, this compound exhibits cytotoxic effects on CHO cells, presenting an IC50 value of 48.1 µM. Antimycobacterial agent-2 is suitable for research applications focused on tuberculosis and related mycobacterial infections.
  34. Antibacterial Agent

    Cyclo(prolyltyrosyl) is a cyclic dipeptide known for its antibacterial activity. It exhibits potent effects against various bacterial strains, making it a valuable tool for research into antimicrobial agents. Additionally, this compound demonstrates phytotoxic and cytotoxic properties, providing potential applications in studies related to plant defense mechanisms and cancer research.
  35. Antibacterial Agent

    3-Hydroxyglabrol is an antibacterial agent derived from Glycyrrhiza glabra L. var. typica. It demonstrates significant inhibitory activity against Staphylococcus aureus (ATCC 13709) and Mycobacterium smegmatis (ATCC 607), with a minimum inhibitory concentration (MIC) of 6.25 mcg/mL. This compound is valuable for research focused on infections caused by these bacterial strains, contributing to the development of potential therapeutic strategies.
  36. Bacterial Inhibitor

    Propioxatin B is a tricyclic sesquiterpenoid compound that acts as a bacterial inhibitor. This compound demonstrates significant anti-tuberculosis activity, exhibiting effectiveness against various drug-resistant Mycobacterium tuberculosis strains. In silico docking studies indicate that Propioxatin B binds with bacterial DNA gyrase, suggesting a targeted mechanism of action and potential safety in in vivo applications.
  37. Antibacterial Agent

    Dunnianol is a natural sesqui-neolignan that acts as an antibacterial agent. It demonstrates moderate antibacterial activity against Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research applications focused on antimicrobial resistance and the development of new antibacterial therapies.
  38. Antibacterial

    Methyl isocostate is a natural compound with demonstrated antibacterial activity, isolated from the plant Globba schomburgkii. This compound is of interest for its potential applications in antimicrobial research and the development of new antibacterial agents. Its unique properties make it a valuable reagent in studies aimed at understanding bacterial resistance and screening for effective antibacterial pharmaceuticals.
  39. Bacterial Inhibitor

    Drimentine A is a terpenylated diketopiperazine that acts as a bacterial inhibitor, originally isolated from Actinomycete bacteria. It exhibits significant antibacterial activity, making it a valuable tool in microbiological studies. This compound is primarily utilized in research involving bacterial pathogenesis and the development of antimicrobial agents. Unlike its analogs Drimentine B and C, Drimentine A does not possess anticancer activity.
  40. Antibacterial Agent

    Dodicin is an antibacterial agent that exhibits broad-spectrum antimicrobial activity. It targets bacterial cell membranes, disrupting their integrity and leading to cell death. This reagent is suitable for use in various research applications, including microbiological studies and disinfectant efficacy evaluations.
  41. Antibacterial Agent

    DC-159a is an 8-methoxyfluoroquinolone that functions as a broad-spectrum antibacterial agent. This compound demonstrates significant antimicrobial activity against various Gram-positive pathogens, including Peptostreptococcus, Clostridium difficile, and Bacteroides fragilis, with minimum inhibitory concentration (MIC90) values of 0.5, 4, and 2 μg/mL, respectively. DC-159a is suitable for research applications focused on antibacterial resistance and infection treatment.
  42. Antibacterial

    NR-NO2 is an innovative antibacterial agent that acts by producing reactive nitrogen species, thereby disrupting bacterial cell function. Its bioactivity involves the inhibition of bacterial growth, making it suitable for research applications in the development of new antibacterial therapies. Additionally, NR-NO2 offers potential in imaging-based guidance due to its unique targeting capabilities, enhancing its use in both antitumor and antibacterial research contexts.
  43. Antibacterial/anticancer Agent

    1-Hydroxy-3,5-dimethoxyxanthone, a xanthone derivative, serves as an effective antibacterial and anticancer agent. Isolated from Lomatogonium rotatum, this compound demonstrates inhibitory effects on the growth of Pseudomonas aeruginosa and Escherichia coli, achieving a minimum inhibitory concentration (MIC) of 640 μg/mL. Additionally, 1-Hydroxy-3,5-dimethoxyxanthone shows significant anticancer activity against various cancer types, including cervical, breast, melanoma, liver, and gastric cancers, making it a valuable tool for biological research and therapeutic development.
  44. Antibacterial Agent

    4-Ethyloctane is a potent antibacterial agent targeting bacterial infections. Demonstrating strong activity against Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 0.04 mg/mL, it serves as a valuable compound for the study of antibacterial properties and mechanisms. Researchers can utilize 4-Ethyloctane in investigations aimed at understanding bacterial resistance and the development of potential therapeutic applications.
  45. Antibacterial Agent

    8-Hydroxy-9,10-diisobutyryloxythymol is a natural monoterpenoid that functions as an antibacterial agent. It demonstrates significant activity against various bacterial strains, including Staphylococcus aureus, Shigella flexneri, and Salmonella paratyphi-B, with minimal inhibitory concentration (MIC) values of 6.25 μg/mL. This compound is valuable for research in antimicrobial efficacy and the development of new antibacterial therapies.
  46. Antibacterial Agent

    Antibacterial Agent 108 is a potent antibacterial compound targeting bacterial pathogens. It exhibits a minimum inhibitory concentration (MIC) of 3 μM against methicillin-resistant Staphylococcus aureus (MRSA) and other antibiotic-resistant strains. This compound is suitable for research applications in studying bacterial infections and developing new antibacterial therapies.
  47. Antibacterial Agent

    Altromycin A is a natural antibacterial agent classified as a Pluramycin analog. It demonstrates significant activity against a range of bacterial strains, making it a valuable tool for studying bacterial infections and developing new antimicrobial strategies. Its mechanism of action involves interference with protein synthesis, which is critical for bacterial growth and survival. Research applications include antibiotic susceptibility testing and the investigation of resistance mechanisms.
  48. Antibacterial Agent

    YXL-13 is a potent inhibitor of Pseudomonas aeruginosa (PAO1) with an IC50 value of 3.686 μM. This compound effectively targets the quorum sensing (QS) system, leading to inhibition of virulence factors and biofilm formation, thereby reducing both pathogenicity and antibiotic resistance. YXL-13 is suitable for research applications focused on the development of antibacterial strategies against PAO1 infections.
  49. Antibacterial Agent

    11-Keto fusidic acid is an antibacterial agent that demonstrates potent activity against Staphylococcus aureus, exhibiting a minimal inhibitory concentration (MIC) of 0.078 μg/mL. Its effectiveness makes it a valuable compound for research focused on microbial infections and the development of novel antibacterial therapies. This compound can aid in the exploration of resistance mechanisms and therapeutic strategies in bacterial pathogenesis.
  50. antibacterial

    Emeguisin A is a depsidone that exhibits notable antibacterial activity. It has been shown to inhibit cell viability in human colon carcinoma (HCT-116) cells by approximately 87.06%. This compound is valuable for research applications focused on developing antibacterial agents and studying the effects of natural products on cancer cell lines.

Items 1251-1300 of 1393

Page
per page
Set Descending Direction