Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Levonadifloxacin arginine is a potent bacterial inhibitor targeting both methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA). This broad-spectrum antistaphylococcal agent exhibits significant antimicrobial activity and has been shown to reduce the phagocytosis of MRSA and MSSA strains by monocytic THP-1 cells. Its applications in research include studies focused on bacterial resistance mechanisms and potential therapeutic interventions for staphylococcal infections. -
Antibacterial Agent
WU-FA-01 is a hydrogenated derivative of WU-FA-00, functioning primarily as an antibacterial agent. It demonstrates potent antibacterial activity against Gram-positive bacterial strains, making it a valuable compound for research into antimicrobial therapies. Additionally, WU-FA-01 exhibits some anti-inflammatory properties, suggesting potential applications in studies focused on the interplay between bacterial infections and inflammation. -
Antibacterial Agent
Isomagnolol is a lignan known for its antibacterial properties. Isolated from the roots of the tea plant, it exhibits significant antimicrobial activity, making it a valuable reagent for research focused on combating bacterial infections. This compound can be utilized in studies investigating the mechanisms of action behind antibacterial agents and in the development of novel therapeutic strategies. -
Bacterial Inhibitor
Antibacterial Agent 53 is a potent bacterial inhibitor that targets specific bacterial pathways to disrupt cell function. Demonstrating significant antibacterial activity, this compound is primarily utilized in research focusing on the development of novel antimicrobial agents and therapeutic strategies against bacterial infections. Its effectiveness makes it a valuable reagent for studies aimed at understanding bacterial resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 109 is an effective antibacterial compound that targets protein synthesis by inhibiting the elongation of peptide chains. It demonstrates strong activity against both gram-positive and gram-negative bacteria while exhibiting non-mutagenic properties. This compound is suitable for research applications focused on bacterial resistance and the mechanisms of antibiotic action. -
Bacterial Inhibitor
Anti Gram-Positive/Negative Bacteria Agent 1 is a bacterial inhibitor that functions through the mechanism of an antibiotic conjugate linked to an artificial MECAM-based siderophore. This compound exhibits significant antibacterial activity against both Gram-positive and Gram-negative bacteria. It is suitable for research applications aimed at studying bacterial infections and developing new antimicrobial strategies. -
Antibacterial Agent
Antibacterial Agent 117 is a triazole derivative that functions as an effective antibacterial agent targeting MetAP1 in Rickettsia prowazekii, exhibiting an IC50 value of 15 μM. This compound demonstrates the ability to inhibit rickettsial growth, making it valuable for research focused on infectious diseases. Its potential applications include investigating mechanisms of bacterial resistance and developing therapeutic strategies against rickettsial infections. -
Antibacterial Agent
ST166 free acid is an inhibitor of the PhoP-DNA complex formation, exhibiting IC50 values of 18 µM and 24 µM against PhoP and MtrAC binding to DNA, respectively. This compound demonstrates significant antibacterial activity against Macrobacterium marinum, making it a valuable tool for studying bacterial infections and pathways. Its application in research contributes to the understanding of bacterial resistance mechanisms and the development of novel antibacterial strategies. -
Bacterial Inhibitor
Antitubercular agent-9 is a bacterial inhibitor that demonstrates effective antitubercular activity, with a minimum inhibitory concentration (MIC) ranging from 1.03 to 2.32 μM. This compound is suitable for research focused on tuberculosis treatment mechanisms and the development of new antitubercular therapies. It serves as a valuable tool for understanding bacterial resistance and evaluating potential drug candidates in infectious disease research. -
Antibacterial Agent
Antibacterial Agent 143 (Compound 5a) is a synthetic antibacterial agent that demonstrates effective antimicrobial activity with minimum inhibitory concentrations (MICs) of 25 μg/mL against Bacillus subtilis ATCC 6633 and Staphylococcus aureus ATCC 6538, and 50 μg/mL against Pseudomonas aeruginosa ATCC 13525 and Escherichia coli ATCC 35218. Its potency against a range of Gram-positive and Gram-negative bacteria makes it a valuable tool in antibacterial research and the development of novel therapeutic strategies. This compound is suitable for studies focusing on bacterial resistance mechanisms and the evaluation of new antibacterial formulations. -
Bacterial Inhibitor
Antibacterial Agent 62 is a novel redox cycling compound that targets bacterial cells, demonstrating potent bactericidal activity against both growing and nutrient-starved phenotypically drug-resistant nongrowing bacteria. This reagent is particularly useful in research applications focused on tuberculosis and the development of new antibacterial therapies. Its unique mechanism of action may also aid in understanding resistance mechanisms in various bacterial strains. -
Antibacterial Agent
D-K6L9 is an antibacterial agent that exhibits significant antimicrobial and antibiofilm activities against Pseudomonas aeruginosa strains isolated from cystic fibrosis patients. This compound demonstrates stability and resistance to degradation by proteases found in cystic fibrosis sputum, which contributes to its effective performance. Importantly, D-K6L9 does not promote bacterial resistance, making it a valuable tool for research in infectious diseases associated with cystic fibrosis. -
Antibacterial Agent
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] is a cyclic peptide exhibiting potent antibacterial properties, effective against both drug-resistant Gram-positive and Gram-negative bacteria. It demonstrates minimum inhibitory concentrations (MICs) of 3.1 µg/mL against MRSA (ATCC BAA-1556) and S. aureus (ATCC 29213), and 12.5 µg/mL and 25 µg/mL against P. aeruginosa (ATCC 27883) and E. coli (ATCC 25922), respectively. This compound serves as a crucial tool for researchers exploring novel antibacterial strategies and understanding resistance mechanisms in pathogenic bacteria. -
Antibacterial Agent
Antibacterial Agent 46 is a potent antibacterial agent, specifically developed for targeting bacterial infections. It demonstrates significant inhibitory activity against a range of pathogenic bacteria, making it a valuable tool for research in the field of microbiology. This compound can be utilized in studies aimed at understanding bacterial resistance mechanisms and developing new antibacterial therapies. -
Bacterial Inhibitor
Antibacterial Agent 30 is a potent bacterial inhibitor, exhibiting significant in vitro activity against Xanthomonas oryzae pv. oryzae with an EC50 value of 1.9 μg/mL. This compound is suitable for research applications aimed at understanding bacterial pathogenesis and developing new antibacterial strategies. -
Bacterial Inhibitor
NDM-1 inhibitor-2 is a selective inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) that effectively inhibits NDM-1 enzymatic activity. This compound demonstrates significant antibacterial activity against drug-resistant bacterial strains that overexpress NDM-1, providing insights into overcoming resistance mechanisms. Additionally, NDM-1 inhibitor-2 can enhance the efficacy of the carbapenem antibiotic meropenem, resulting in a synergistic effect that supports research in antimicrobial therapy and resistance management. -
Antibacterial Drug
1,3,7-Trihydroxy-2-prenylxanthone is a xanthone derivative with antibacterial properties primarily targeting vancomycin-resistant enterococci (VRE). It demonstrates a minimum inhibitory concentration (MIC) of 6.25 mg/ml against strains including Enterococcus faecalis, Enterococcus faecium, and Enterococcus gallinarum. This compound is valuable for research applications focused on antibiotic resistance and the development of novel antibacterial agents. -
Antibacterial Drug
(±)-ε-Viniferin is a racemic mixture known for its antibacterial properties, primarily targeting Gram-positive bacteria. It demonstrates antimicrobial activity against Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) of 20 μM. Additionally, (±)-ε-Viniferin exhibits P450 inhibitory effects and protective properties for hepatocytes, making it a valuable compound in research on antibacterial agents and hepatoprotection. -
Bacterial Inhibitor
1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial agent targeting a range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). Its significant antibacterial activity makes it a valuable candidate for addressing drug-resistant bacterial infections. Research applications may include investigations into its efficacy as a therapeutic tool against prevalent multidrug-resistant pathogens in clinical settings. -
Antibacterial Peptide
LDKA is a helical membrane-active antibacterial peptide that primarily disrupts bacterial membranes. This compound demonstrates significant antibacterial activity against both Gram-positive bacteria, such as Staphylococcus aureus, and Gram-negative bacteria, including Escherichia coli and Pseudomonas aeruginosa, in nutrient-rich environments. The minimum inhibitory concentrations (MICs) for LDKA range from 10 to 70 μM, making it a valuable tool for research in antibacterial therapeutic development. -
Antibacterial Drug
Galbinic acid (α-Acetylsalazinic acid) is an antibacterial compound that targets and inhibits the growth of various bacterial strains. It demonstrates significant activity against Gram-positive bacteria such as Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus, with minimum inhibitory concentrations (MICs) of 62.5 μg/ml and 250 μg/ml, respectively. Additionally, Galbinic acid exhibits antibacterial effects on the Gram-negative bacterium Escherichia coli, with an MIC of 125 μg/ml. This compound is valuable for research applications focused on developing new antibacterial agents. -
Antibacterial Agent
Corianin is a sesquiterpene lactone extracted from the fruits of Coriaria ruscifolia, exhibiting potent antibacterial properties. It demonstrates effectiveness against Staphylococcus aureus and Staphylococcus epidermidis, making it a valuable compound for research into antibacterial mechanisms and potential therapeutic applications. This compound may serve as a candidate in the development of new antimicrobial agents. -
Bacterial Inhibitor
Altertoxin III is a bacterial inhibitor known for its mutagenic effects on Salmonella typhimurium strains TA98, TA100, and TA1537. Derived from an extract of the A. alternata isolate, this compound exhibits significant mutagenicity as demonstrated in the Ames assay. It is valuable for studies focused on mutagenesis and the mechanisms of bacterial resistance. -
Antibacterial Agent
Antibacterial Agent 33 functions primarily as an antibacterial agent, exhibiting enhanced efficacy by significantly lowering the minimum inhibitory concentration (MIC) of Ceftazidime. This compound demonstrates potent antibacterial activity against a range of pathogenic bacteria, making it a valuable tool for research in antibiotic synergy and resistance mechanisms. Its applications include studies in microbiology and pharmacology, particularly in the development of novel antibacterial therapies. -
Bacterial Inhibitor
Heraclenol is a coumarin compound that targets bacterial pathogens. Isolated from the fruits of Angelica lucida, Heraclenol demonstrates notable antibacterial activity, making it valuable for research applications focused on combatting bacterial infections. Its mechanism of action contributes to the understanding of antimicrobial resistance and the development of new therapeutic strategies. -
Antibacterial Agent
Antibacterial Agent 74 is a potent anti-Salmonella compound that demonstrates significant antibacterial activity against Salmonella spp. This reagent is essential for research applications focused on understanding bacterial infections and developing novel therapeutic strategies to combat Salmonella-related diseases. -
Bacterial Inhibitor
L-689065 is a potent bacterial inhibitor that acts by targeting essential bacterial processes. It exhibits significant antimicrobial activity against a range of bacterial strains, making it a valuable reagent for studies on bacterial resistance and infection mechanisms. This compound is applicable in microbiological research focused on identifying new antibacterial agents and understanding the pathways of bacterial growth inhibition. -
Bacterial Inhibitor
FK-518 is a potent inhibitor of AmpC β-lactamase, targeting resistance mechanisms in bacteria. This compound exhibits strong antimicrobial activity against Pseudomonas aeruginosa strains that overexpress AmpC β-lactamase, making it a valuable tool in the study of bacterial infections. FK-518 is particularly useful for research investigating therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
Antibacterial Agent 197 (compound 1-deAA) functions as a termination inhibitor of non-classical anhydroglycosyl receptors and anhydrowall peptide-type peptidoglycan in bacterial TGase. This compound exhibits notable antibacterial activity against Staphylococcus aureus and can enhance the efficacy of Vancomycin, serving as an effective antibacterial adjuvant. It is suitable for research applications focused on antibiotic resistance and the development of novel antibacterial strategies. -
Antibacterial Agent
Isobavachromene is an antibacterial agent that exhibits potent activity against various bacterial strains. Its primary mechanism involves the disruption of bacterial cell wall synthesis, leading to cell lysis and death. This compound is valuable for research applications focused on exploring novel antibacterial therapies and understanding microbial resistance mechanisms. -
Antibacterial Agent
MAC173979 is an inhibitor of para-aminobenzoic acid (PABA) synthesis in Escherichia coli. This compound exhibits significant antibacterial activity, making it a valuable tool for the exploration of antibacterial drug development and mechanisms of resistance. Researchers can utilize MAC173979 to study the efficacy of novel antibacterial agents and develop therapeutic strategies targeting bacterial infections. -
Antibacterial Agent
Antibacterial Agent 43 is a potent antibacterial compound targeting bacterial strains implicated in various infections. This agent exhibits significant antimicrobial activity, making it suitable for investigating the mechanisms of bacterial resistance and the development of new therapeutic strategies. Its applications extend to research focused on treating bacterial infections and understanding the pharmacodynamics of antibacterial therapies. -
Antibacterial agent
PuroA is an antibacterial agent derived from the tryptophan-rich domain of Puroindoline a. It exerts its antibacterial activity by interacting with bacterial membranes, disrupting their integrity. This compound is valuable for research applications focused on understanding bacterial resistance and developing novel antimicrobial strategies. -
Antibacterial Agent
Tetrahydrobostrycin is a secondary metabolite derived from Aspergillus species, functioning primarily as an antibacterial agent. It demonstrates mild inhibitory activity against pathogens such as Staphylococcus aureus and Escherichia coli, with observed inhibition zones measuring 15 mm and 9.2 mm in diameter, respectively, at a concentration of 100 mg/disc. This compound may be useful in microbiological research and investigations into antibacterial mechanisms. -
Bacterial Inhibitor
RO7075573 is a bacterial inhibitor that targets the lipopolysaccharide (LPS) transport machinery in Acinetobacter species. This compound has demonstrated protective effects in preclinical models against Acinetobacter baumannii infections, highlighting its potential for therapeutic applications in combating antibiotic-resistant bacterial pathogens. Research applications may include studying bacterial pathogenesis and developing new antibiotic strategies. -
Antibacterial Agent
Tenonitrozole is an antibacterial agent that acts primarily by inhibiting pyruvate-ferredoxin oxidoreductase (PFOR). This compound exhibits notable antibacterial activity against Helicobacter pylori and Campylobacter jejuni, with minimum inhibitory concentrations (MICs) of 0.7 μM and 5.9 μM, respectively. Tenonitrozole is useful in research applications focused on bacterial infections and antibiotic resistance studies. -
Bacterial Inhibitor
Neorauflavene is a phenolic isoflavonoid derived from Neorautanenia edulis, functioning as a bacterial inhibitor. This compound exhibits significant antibacterial activity against various strains, including Enterococcus faecalis, Streptococcus suis, Streptococcus agalactiae, Pseudomonas aeruginosa, Bacillus subtilis, and Riemerella anatipestifer. Neorauflavene's antibacterial properties make it a valuable tool for research in microbiology and the development of therapeutic agents targeting bacterial infections. -
Bacterial Virulence Factor Inhibitor
Anti-virulence factor-IN-1 is a bacterial virulence factor inhibitor that disrupts the bacterial infection process. It demonstrates potent antibacterial activity against Xanthomonas oryzae pv. oryzae (Xoo) with an EC50 value of 0.28 µg/mL. This compound is applicable for the management of rice bacterial leaf blight in vivo and offers significant potential for research related to plant bacterial diseases. -
Antibacterial Agent
Antibacterial Agent 125 is an antibacterial compound that exhibits potent antimicrobial activity against clinically relevant Gram-positive pathogens, with MIC50 values ranging from 0.25 to 8 μM. This compound serves as a valuable tool in research focused on antimicrobial resistance, enabling studies to explore mechanisms of action and resistance patterns in bacterial strains. -
Antibacterial Agent
Antibacterial Agent 75, known as compound 24, functions as a potent antibacterial agent. It has demonstrated efficacy in re-sensitizing vancomycin-resistant Staphylococcus aureus (VRSA) to vancomycin, making it a valuable tool in combating antimicrobial resistance. This compound is essential for research focused on developing strategies to enhance antibiotic effectiveness against resistant bacterial strains. -
Antibacterial Agent
TXY541 is an orally active antibacterial agent that demonstrates potent activity against Staphylococcus aureus. Under physiological conditions, it can be converted to PC190723, which enhances its efficacy. TXY541 exhibits low toxicity to mammalian cells, making it suitable for various antibacterial research applications. -
Bacterial
KSK213 is a 1,2,3-triazole derivative that functions as a potent inhibitor of Chlamydia infectivity, exhibiting a half-maximal effective concentration (EC50) of less than 20 nM. This compound is valuable for research into Chlamydia infections and can aid in the development of therapeutic strategies against bacterial pathogens. Its high potency makes it an essential tool for studying bacterial infectivity mechanisms and evaluating potential antimicrobial treatments. -
Bacterial Peptide Deformylase Inhibitor
Lanopepden camsylate is a high-affinity inhibitor of bacterial peptide deformylase, an enzyme critical for protein maturation in bacteria. This compound exhibits potent activity against bacterial infections by disrupting essential protein processing. Lanopepden camsylate is primarily utilized in research applications focused on the development of new antibacterial agents and the study of bacterial pathogenicity. -
Bacterial Inhibitor
TP-271 is a bacterial inhibitor specifically designed to target pathogens associated with community-acquired pneumonia. This compound exhibits significant antimicrobial activity, making it suitable for research applications focused on bacterial infections and respiratory diseases. Its potential to disrupt bacterial growth presents promising avenues for further exploration in the development of effective therapeutics. -
Bacterial Inhibitor
Cefonicid is a broad-spectrum beta-lactam antibiotic targeting bacterial cell wall synthesis. It exhibits potent antibacterial activity against a variety of Gram-positive and Gram-negative bacteria, making it valuable in treating various infectious diseases. Pharmacokinetic studies indicate that high plasma concentrations are swiftly attained following intravenous or intramuscular administration, and its half-life may be extended with concomitant use of albendazole, leading to reduced renal clearance. Cefonicid serves as an essential tool in bacterial infection research and the development of therapeutic strategies. -
Anti-bacterial Agent
3′-Omethyl-5′-hydroxydiplacone is a C-6-geranylflavonoid with demonstrated antibacterial activity, specifically targeting Gram-positive bacteria. This compound, isolated from the ethanol extract of Paulownia tomentosa fruits, serves as a valuable tool for studies focused on bacterial inhibition and antimicrobial research. Its unique structure and functionality make it of interest for investigating the mechanisms of antibacterial agents. -
Antibacterial Agent
Antibacterial Agent 116 is a benzophenone-containing salicylanilide compound that acts by inhibiting peptidoglycan formation, a critical component of bacterial cell walls. This compound demonstrates potent antibacterial activity and serves as a photoaffinity probe to specifically label Acinetobacter baumannii penicillin-binding protein (PBP1b). Its use is vital in research applications focused on understanding bacterial growth mechanisms and developing strategies to combat antibiotic resistance. -
Bacterial Inhibitor
Penicillin N is a penicillin-type antibiotic that primarily targets bacterial cell wall synthesis. It exhibits potent antibacterial activity against enteric bacilli, making it effective for the treatment of infections caused by these pathogens. This compound is widely utilized in microbiological research to study antibacterial mechanisms and evaluate susceptibility of bacterial strains. -
Bacterial Inhibitor
Methyl sterculate is a potent bacterial inhibitor that targets Δ9 desaturase. This compound effectively inhibits the growth of Rhodococcus opacus at a concentration of 0.75 mM, demonstrating toxicity towards the bacteria. Furthermore, it alters the fatty acid profile by decreasing overall fatty acid content while increasing the palmitate ratio and reducing stearate and oleate levels at concentrations of 0.25 or 0.5 mM. Methyl sterculate also exhibits a synergistic effect on tumor growth induced by aflatoxin Q1 in rainbow trout at a concentration of 50 ppm. -
Antibacterial Agent
Cis-2-Dodecenoic acid is an antibacterial agent that disrupts bacterial quorum sensing mechanisms. Derived from Burkholderia cenocepacia, this compound effectively inhibits biofilm formation and the production of virulence factors in bacteria. Its unique action makes it valuable for research into antimicrobial resistance and biofilm-related infections.
