Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
CI-990 (PD-131112) is a selective inhibitor of bacterial DNA gyrase, targeting key enzymes involved in DNA replication and repair. It exhibits potent antibacterial activity and is especially relevant for studying Enterococcal infections, including endocarditis and sepsis. This compound can serve as a valuable tool in microbiological research to understand bacterial resistance mechanisms and develop therapeutic strategies. -
Bacterial Transcription Inhibitor
CUHK242 is a selective bacterial transcription inhibitor that effectively disrupts RNA synthesis within bacterial cells. It demonstrates a minimum inhibitory concentration (MIC) of 2 μg/mL against the B. subtilis reporter strain BS2019 and exhibits antimicrobial activity against Staphylococcus aureus. This compound is useful for research applications focused on understanding bacterial gene expression and studying the mechanisms of antibiotic resistance. -
Anti-Bacterial Agent
(Rac)-Besifloxacin hydrochloride is a fourth-generation fluoroquinolone antibiotic that acts as a potent inhibitor of DNA gyrase and topoisomerase IV. This compound exhibits broad-spectrum antibacterial activity against both Gram-negative and Gram-positive aerobic and anaerobic bacteria, making it valuable in combating drug resistance. Additionally, (Rac)-Besifloxacin hydrochloride possesses anti-inflammatory properties, and it is relevant in the study of bacterial conjunctivitis. -
Bacterial DNA Gyrase B Inhibitor
DNA Gyrase-IN-2 is a potent inhibitor of bacterial DNA gyrase B, demonstrating IC50 values of 3.29-10.49 µM for Escherichia coli and 4.41-5.61 µM for Mycobacterium tuberculosis. This compound exhibits significant anti-tubercular and antibacterial activity, making it valuable for research focused on bacterial replication and antibiotic development. Its specific targeting of DNA gyrase B positions it as a promising candidate for further investigation in treating bacterial infections. -
Antibacterial Agent
S-MGB-234 is an antibacterial agent that functions as a minor groove binder, specifically targeting the causative agents of Animal African Trypanosomiasis (AAT). This compound demonstrates potent in vitro activity against Trypanosoma congolense and Trypanosoma vivax, the primary pathogens responsible for AAT. Notably, S-MGB-234 exhibits a unique resistance profile, lacking cross-resistance with existing diamidine agents and not utilizing the transporters commonly associated with diamidines. -
Antibacterial Agent
Lavofloxacin lactate is an antibacterial agent that primarily targets DNA gyrase and topoisomerase IV, leading to the inhibition of DNA replication and repair in bacteria. This broad-spectrum antimicrobial compound exhibits potent bactericidal activity against a wide range of bacterial species. Researchers can utilize Lavofloxacin lactate to investigate bacterial resistance mechanisms, including the analysis of resistance genes and mutations. -
Antibacterial Agent
A-65282 is an antibacterial agent that inhibits P4 DNA unknotting, exhibiting an IC50 value of 8 µg/mL. This compound induces DNA breakage through the action of calf thymus topoisomerase II, making it a valuable tool for studying DNA replication and repair mechanisms. Its targeted enzymatic disruption highlights its potential in antibacterial research contexts. -
Antibacterial Agent
Anti-MRSA agent 28 is an antibacterial agent specifically designed to target multidrug-resistant (MDR) gram-positive bacterial strains. With minimum inhibitory concentrations (MICs) ranging from 0.06 to 0.125 μg/mL, it effectively inhibits bacterial growth by targeting DNA polymerase IIIC, demonstrating an IC50 of 3.80 μg/mL. This compound exhibits strong antibacterial activity and has anti-inflammatory properties, making it a valuable tool for research applications related to the treatment of gram-positive infections. -
Antibacterial Agent
DV-7751A is a fluoroquinolone antibiotic that primarily inhibits the supercoiling activity of DNA gyrases. This compound demonstrates significant antimicrobial activity against a range of bacterial strains, including Streptococcus pneumoniae, Streptococcus pyogenes, and Peptostreptococcus species. Additionally, DV-7751A exhibits a rapid bactericidal effect against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa, making it a valuable reagent for research in antibacterial therapeutics. -
Insecticide/Antibacterial Agent
Satranidazole is an orally active insecticide and antimicrobial agent that primarily targets DNA through the formation of reduced nitro intermediates. By inducing helix instability and strand breakage, it exhibits notable antitrichomonal activity against organisms such as Trichomonas vaginalis and Trichomonas foetus, as well as antiamoebic effects in rodent models of hepatic and caecal amoebiasis. Additionally, Satranidazole has been shown to inhibit the replication of bacteriophage φX174 DNA. This compound is valuable for research exploring caecal amoebiasis, trichomoniasis, and anaerobic bacterial infections. -
Antibacterial/anti-inflammatory Agent
Sinapaldehyde is a methoxyphenol that primarily functions as a selective COX-2 inhibitor with an IC50 of 47.8 µM. This compound exhibits notable antibacterial and anti-inflammatory properties, demonstrating efficacy against both Gram-positive and Gram-negative bacteria. Additionally, Sinapaldehyde possesses antioxidant activity through its ability to scavenge DPPH free radicals, with an IC50 of 172 μM, making it a valuable reagent for research in inflammation and microbial resistance. -
Antibacterial Agent
1-Tetradecanol is a straight-chain saturated fatty alcohol that serves as an effective antibacterial agent. Isolated from Myristica fragrans, it exhibits notable antibacterial and anti-inflammatory properties, particularly in the context of periodontitis. This compound can be utilized in research applications focusing on antimicrobial activity and the modulation of inflammatory responses. -
Antibacterial Agent
Terminolic acid is a pentacyclic triterpene glycoside that acts as an antibacterial agent. It exhibits significant antibacterial activity against Staphylococcus aureus, Escherichia coli, and Enterococcus faecalis, with minimum inhibitory concentrations (MICs) ranging from 64 to 256 μg/mL. Terminolic acid also demonstrates the ability to inhibit pro-inflammatory cytokines by binding to the receptor active sites of IL-1β and IL-6, contributing to a reduction in IL-8 levels. This compound is utilized in research targeting colon cancer and inflammatory conditions. -
Antibacterial Agent
Antibacterial Agent 69 is a novel antimicrobial compound that targets and inhibits the growth of multidrug-resistant bacteria. With a reported minimum inhibitory concentration (MIC) of 2.978 μM, it demonstrates significant antibacterial activity. This agent is primarily employed in research focused on combating antibiotic resistance and developing new therapeutic strategies against challenging bacterial infections. -
Anti-inflammatory/Antioxidant/Antibacterial Agent
Eukovoside is a cinnamic acid derivative that primarily exerts anti-inflammatory, antioxidant, and antibacterial effects. This compound shows potential in the study of hyperglycemic diseases and is useful for investigating various inflammatory conditions, including eye inflammation and respiratory tract disorders. Additionally, Eukovoside may contribute to research focused on allergic responses such as hay fever and conjunctivitis, as well as infections like colds, influenza, and sinusitis. -
Bacterial Inhibitor
Ethionamide is a second-line anti-tuberculosis agent that acts primarily by inhibiting the synthesis of mycolic acids in Mycobacterium tuberculosis. This compound demonstrates significant antibacterial activity and is effective when administered orally. Ethionamide is utilized in research applications focused on tuberculosis treatment resistance mechanisms and the development of novel therapeutics against mycobacterial infections. -
Bacterial Inhibitor
Fleroxacin is a broad-spectrum fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication and transcription. This compound exhibits potent antibacterial activity against a wide range of gram-negative and some gram-positive bacteria. Fleroxacin is suitable for research applications focused on the elucidation of bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
Bacterial Inhibitor
Nitrofurazone is a nitro-aromatic antibacterial compound primarily targeting bacterial DNA and RNA synthesis. It exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria, making it suitable for a variety of microbiological research applications. Nitrofurazone is often utilized in studies assessing antimicrobial resistance and the efficacy of antibiotic treatments. -
Bacterial Inhibitor
Teicoplanin is a glycopeptide antibiotic primarily targeting Gram-positive bacteria, demonstrating potent activity against methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus aureus. In addition to its antibacterial properties, teicoplanin exhibits antiviral effects against HIV-1, SARS-CoV-1, and SARS-CoV-2. This versatile compound is utilized in research related to bacterial resistance and viral infections, making it a valuable tool for studying antimicrobial efficacy and therapeutic interventions. -
Bacterial Inhibitor
Tobramycin is a broad-spectrum aminoglycoside antibiotic that primarily targets bacterial protein synthesis by binding to the 30S ribosomal subunit. It exhibits significant antibacterial activity against a variety of Gram-negative and some Gram-positive bacteria. Tobramycin is particularly effective in research applications focused on infections caused by Pseudomonas aeruginosa, including studies related to pneumonia. Its efficacy makes it a valuable reagent in microbial pathogenesis and antibiotic resistance research. -
Antibacterial Agent
Mafenide hydrochloride is a sulfonamide-type antimicrobial agent that targets bacterial infections. It exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa, primarily through the inhibition of nucleotide synthesis. Mafenide hydrochloride is commonly utilized in the treatment of burn wounds, making it a valuable reagent in research focused on wound healing and infection control. -
Bacterial Inhibitor
Ampicillin sodium is a broad-spectrum beta-lactam antibiotic that targets bacterial cell wall synthesis. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable reagent for microbiological research. Ampicillin sodium is commonly used in cell culture and for selecting genetically modified organisms, as well as in the study of bacterial resistance mechanisms. Its ability to inhibit bacterial growth supports investigations into antibiotic efficacy and microbial interactions. -
Bacterial Inhibitor
Cefoperazone is a semisynthetic cephalosporin that functions as a bacterial inhibitor by interfering with cell wall synthesis. It exhibits a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative bacteria. This reagent is commonly employed in microbiological research to study bacterial infections and assess the efficacy of antimicrobial agents. -
Bacterial Inhibitor
Erdosteine functions as a bacterial inhibitor by inhibiting lipopolysaccharide (LPS)-induced activation of NF-κB. This compound exhibits muco-modulatory, anti-bacterial, anti-inflammatory, and antioxidant properties. Erdosteine is primarily utilized in research applications focused on respiratory disorders and inflammation, supporting the study of therapeutic interventions in these areas. -
Bacterial Inhibitor
Erianin is a bacterial inhibitor that exhibits potent anticancer properties by inhibiting indoleamine 2,3-dioxygenase (IDO). This activity contributes to its ability to suppress tumor angiogenesis, making it a valuable compound in cancer research. Erianin's dual role as an antipyretic and analgesic further broadens its potential applications in therapeutic studies. -
Bacterial Inhibitor
Allicin (diallyl thiosulfinate) is a potent bacterial inhibitor derived from garlic extracts, primarily responsible for the antimicrobial properties of garlic. It demonstrates significant antimicrobial activity against a wide range of microorganisms, including antibiotic-resistant strains, making it a valuable reagent for research in microbiology and pharmacology. Allicin is commonly utilized in studies investigating natural antibacterial compounds and their mechanisms of action. -
Antibacterial Drug
p-Anisic acid, also known as 4-Methoxybenzoic acid, acts primarily as a tyrosinase inhibitor. It exhibits multiple biological activities, including antioxidant, anti-anxiety, anti-inflammatory, anti-tumor, and anti-diabetic effects. This compound is also utilized as a preservative in cosmetic formulations, making it relevant for research in medicinal chemistry and cosmetic science. -
Bacterial Inhibitor
Evoxine, also known as Haplophytin B, is a bacterial inhibitor that selectively targets CO2-induced immunosuppression. It demonstrates significant antimicrobial activity, particularly against common pathogens such as Escherichia coli, Bacillus subtilis, and Staphylococcus aureus, as evidenced by its performance in minimum inhibitory concentration (MIC) assays. Evoxine also inhibits the expression of pro-inflammatory cytokines such as interleukin-6 and chemokine CCL2 in human THP-1 macrophages, indicating its potential utility in therapeutic applications and crude drug preparations, particularly in the context of traditional medicine in West Africa. -
Antibacterial Agent
Ginkgolic Acid (C13:0) primarily functions as an antibacterial agent and a potent PI3Kδ inhibitor (IC50: 2.49 μM). This compound demonstrates significant antibacterial and anti-parasitic activities, making it valuable in microbiological research. Additionally, Ginkgolic Acid (C13:0) is known to inhibit mast cell degranulation with an IC50 of 2.40 μM, contributing to its potential therapeutic applications in inflammatory conditions. -
Bacterial Inhibitor
3,3'-Di-O-methylellagic acid is a bacterial inhibitor derived from Euphorbia adenochlora. It selectively inhibits the development of acid-fastness in mycobacteria without affecting their growth rates. Additionally, this compound exhibits hepatoprotective properties, likely attributed to its antioxidative effects, making it valuable for research in microbial resistance and liver health. -
Bacterial Inhibitor
Methyl Paraben is a bacterial inhibitor primarily used as a preservative in various applications due to its stability and non-volatility. It has been shown to enhance histamine release and modulate cellular immune responses, in addition to blocking sodium channels. Its properties make it valuable for studies exploring microbial inhibition and the mechanisms of ischemia-reperfusion injury. -
Bacterial Biofilm Formation Inhibibitor
D-Phenylalanine is an atypical D-amino acid that functions as a bacterial biofilm formation inhibitor. It integrates into the peptidoglycan layer of bacterial cell walls, particularly replacing D-alanine, which alters cell wall structure and enhances acid resistance, thereby impacting biofilm development. Additionally, D-Phenylalanine may stimulate the secretion of peptide tyrosine tyrosine (PYY) in mammals through activation of the GPR109B receptor, suggesting a role in appetite regulation and blood glucose management. This reagent is valuable for research in antibacterial preservation, probiotic enhancement in the food industry, and metabolic disease studies, including diabetes. -
Antibacterial Agent, Antiviral Agent, Mutagenic Agent, Antiparasitic Agent
Diiodohydroxyquinoline is an antibacterial, antiviral, mutagenic, and antiparasitic agent targeting various pathogens. It demonstrates significant anti-SARS-CoV-2 activity, with an EC50 value of 1.38 μM in VeroE6 cells, and shows effective antiparasitic properties. This compound is of particular interest for research applications involving inflammation, intestinal amebiasis, amebic liver abscess, and chronic nonspecific diarrhea. Additionally, Diiodohydroxyquinoline's mutagenic effects in animal models warrant further investigation in toxicological studies. -
Bacterial Inhibitor
Enrofloxacin is a potent bacterial inhibitor belonging to the fluoroquinolone class. It exhibits an MIC90 value of 0.312 μg/mL against Mycoplasma bovis, demonstrating its effectiveness in combating bacterial infections. This compound is widely utilized in research applications focused on antibiotic resistance, microbiology, and the study of bacterial pathogens. -
Bacterial Inhibitor
Florfenicol is a broad-spectrum antibacterial agent that exerts its effects primarily through inhibition of bacterial protein synthesis. This orally active compound demonstrates additional properties, including anti-inflammatory, pro-apoptotic, and immunomodulatory functions. Florfenicol is commonly utilized in research focused on bacterial infections and the modulation of immune responses. -
Bacterial Inhibitor
Furaltadone hydrochloride is an orally active antibacterial agent targeting bacterial infections. It exhibits in vitro inhibitory effects on Staphylococcus and can be utilized in the study of intestinal Salmonella infections. Additionally, Furaltadone demonstrates potential inhibitory effects on allergic reactions, making it a valuable tool for research in microbiology and immunology. -
Bacterial Inhibitor
Penicillin G sodium salt is a β-lactam antibiotic that inhibits bacterial cell wall synthesis by targeting penicillin-binding proteins. It demonstrates broad-spectrum antibacterial activity against various Gram-positive and some Gram-negative organisms. This reagent is commonly used in microbiological studies to evaluate susceptibility patterns and in the development of antibiotic resistance models. -
Bacterial Inhibitor
Piperacillin sodium is a semisynthetic β-lactam antibiotic that targets penicillin-binding proteins, exhibiting potent bactericidal activity against a broad range of Gram-negative bacteria and select Gram-positive strains. This compound is widely utilized in pharmaceutical research to study bacterial infections and antibiotic resistance. Piperacillin sodium is frequently employed in combination with the β-lactamase inhibitor Tazobactam to enhance its efficacy against resistant bacterial strains. -
Bacterial Inhibitor
Ribostamycin sulfate is a broad-spectrum bacterial inhibitor that targets protein synthesis by binding to the 30S and 50S ribosomal subunits. Additionally, it inhibits the chaperone activity of protein disulfide isomerase (PDI). This reagent is primarily utilized in pharmacokinetic studies and investigations of nephrotoxicity, making it valuable in the evaluation of antimicrobial efficacy and safety profiles. -
Antiprotozoal/Antibacterial Agent
Ronidazole is a potent antiprotozoal and antibacterial agent that targets various protozoan infections. It is particularly effective against Tritrichomonas foetus in cat models, making it a valuable tool for veterinary research. Additionally, Ronidazole is utilized in the study of histomoniasis and swine dysentery, contributing to advancements in understanding these diseases in livestock and companion animals. -
Bacterial Inhibitor
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic that targets bacterial protein synthesis. It exhibits strong antibacterial activity, particularly against Gram-positive bacteria, making it an effective choice in studies of bacterial inhibition. This compound is useful for research applications involving the characterization of bacterial resistance and the development of new antimicrobial strategies. -
Bacterial Inhibitor
Sodium 4-aminosalicylate dihydrate serves as an inhibitor of dihydrofolate reductase (DHFR) and is recognized for its antituberculous properties. This compound exhibits anti-inflammatory effects, making it a valuable tool in the study of inflammatory bowel disease (IBD). Moreover, it is characterized by its oral bioavailability, enhancing its applicability in various research settings. -
Bacterial Inhibitor
Sparfloxacin is a fluoroquinolone antibiotic that primarily targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication. It exhibits broad-spectrum antibacterial activity, making it effective against a variety of Gram-positive and Gram-negative pathogens. Sparfloxacin is commonly used in research applications to study bacterial resistance mechanisms and evaluate new antibacterial strategies. -
Bacterial Inhibitor
Streptomycin sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. It exhibits potent antibacterial activity against a range of Gram-negative and some Gram-positive bacteria, making it useful in both clinical and research settings. This reagent is commonly employed in studies involving microbial resistance, antibiotic efficacy, and protein synthesis mechanisms. -
Bacterial Inhibitor
Sulfamethazine is an antimicrobial agent that acts as a bacterial inhibitor, demonstrating permeability across the blood-brain barrier. It is commonly utilized in veterinary medicine to treat and prevent a variety of animal diseases, including gastrointestinal and respiratory tract infections. Regulatory standards set by China and the European Commission establish a maximum residue level of 100 μg/kg for Sulfamethazine in animal products, underscoring its significance in both therapeutic and safety assessments. -
Antibacterial Agent
Tinidazole is an orally available antibacterial agent belonging to the 5-nitroimidazole class, with selective activity against anaerobic bacteria and protozoa. This compound exhibits potent antimicrobial properties, making it useful in treating infections caused by susceptible organisms. Tinidazole is commonly employed in research focused on bacterial resistance mechanisms and the development of antiparasitic therapies. -
Bacterial Inhibitor
Urethane, also known as ethyl carbamate, is an ethyl ester of carbamic acid that acts as a bacterial inhibitor. It demonstrates the ability to suppress the growth of bacteria, protozoa, sea urchin eggs, and plant tissues in vitro. This compound is primarily utilized in studies examining microbial inhibition and growth regulation in various biological systems. -
Anti-bacterial Agent
Valnemulin hydrochloride is an orally active truncated pleuromutilin antibiotic that inhibits bacterial protein synthesis by binding to peptidyl transferase in the 50S ribosomal subunit. This compound demonstrates significant antibacterial activity against Mycobacterium bovis, effectively reducing infection in experimental bovine models of Mycoplasma bovis. Additionally, Valnemulin hydrochloride reduces mortality associated with epidemic rabbit enteropathy while maintaining growth performance in rabbits, making it a valuable reagent for research in veterinary microbiology. -
Bacterial Inhibitor
Carbadox is a quinoxaline-di-N-oxide antibiotic that functions as a bacterial inhibitor. It is primarily used in veterinary medicine to control enteric infections in nursery-age pigs, enhancing feed efficiency and promoting overall health. Its antibacterial properties make it valuable for research applications focused on veterinary pharmacology and microbiology in the study of antibiotic efficacy and resistance mechanisms. -
Bacterial Inhibitor
Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic that acts as a bacterial inhibitor through the inhibition of protein synthesis. It exhibits broad-spectrum antibacterial activity, making it effective against various skin infections, including acne vulgaris. This reagent is valuable for research into antibiotic resistance and the mechanisms of bacterial infection.
