Bacterial

Items 1351-1393 of 1393

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  1. Antibacterial Agent

    Pasiniazid is a complex formed by the combination of isoniazid and para-aminosalicylic acid in a 1:1 molar ratio, acting primarily as an antibacterial agent targeting Mycobacterium tuberculosis. Upon administration, Pasiniazid decomposes rapidly in the gastrointestinal tract, releasing isoniazid, which exhibits a bactericidal effect, while para-aminosalicylic acid prolongs the acetylation of isoniazid. This compound is valuable for research applications related to tuberculosis and the development of effective treatment regimens.
  2. Bacterial Inhibitor

    Saccharin is a non-caloric artificial sweetener that primarily exhibits bacteriostatic properties. It is recognized for its ability to inhibit bacterial growth and modulate the microbiome. This compound is utilized in various research applications aimed at studying microbial dynamics and the effects of sweeteners on bacterial populations.
  3. Antibacterial Agent

    Flucloxacillin sodium is a beta-lactam antibiotic that primarily targets bacterial cell wall synthesis. It exhibits strong antibacterial activity against a range of gram-positive bacteria, including staphylococci, and is effective against some gram-negative strains. Flucloxacillin sodium is commonly utilized in research to investigate antibacterial resistance mechanisms, as well as in studies focused on the efficacy of antibiotic treatments.
  4. Antibacterial Agent

    Cefathiamidine is a first-generation cephalosporin antibacterial agent targeting bacterial cell wall synthesis. It demonstrates a broad spectrum of antimicrobial activity against various susceptible bacterial strains. This reagent is utilized in the treatment of a range of infections, including respiratory, liver, sensory organ infections, urinary tract infections, endocarditis, and sepsis, making it valuable in both clinical settings and microbiological research.
  5. Anti-bacterial Agent

    Nonanoic acid is a naturally occurring saturated fatty acid that exerts its biological effects primarily through its antibacterial properties. It has been shown to significantly reduce bacterial translocation and enhance antibacterial activity, as well as notably increase the secretion of porcine β-defensins 1 (pBD-1) and pBD-2. This compound serves as a valuable tool in research focusing on bacterial resistance and host defense mechanisms.
  6. Bacterial Inhibitor

    Octenidine dihydrochloride is a potent bacterial inhibitor that functions as an antiseptic. Its primary mechanism involves disrupting microbial cell membranes, which results in effective antimicrobial activity against a broad spectrum of pathogens. This compound is widely utilized in medical and clinical research for its applications in wound care, skin disinfection, and maintaining sterile conditions in various settings.
  7. Antibacterial Agent

    Mupirocin calcium hydrate is an antibacterial agent that functions by reversibly inhibiting isoleucyl-transfer RNA, which subsequently disrupts bacterial protein and RNA synthesis. Isolated from Pseudomonas fluorescens, this orally active antibiotic is effective against a variety of bacterial infections. It is commonly utilized in research settings to investigate mechanisms of antibiotic resistance and protein synthesis in bacteria.
  8. Antibacterial Agent

    Sulfamethazine sodium is an antibacterial agent that exhibits antimicrobial activity with the ability to penetrate the blood-brain barrier. This compound is primarily utilized in veterinary medicine for the treatment and prevention of gastrointestinal and respiratory infections in animals. Regulatory limits for sulfamethazine sodium in animal products have been established by the Chinese authorities and the European Commission, with a maximum residue level set at 100 μg/kg.
  9. Bacterial Inhibitor

    Ceftezole is a broad-spectrum cephem antibiotic that effectively targets both gram-positive and gram-negative bacteria. Its primary mechanism involves inhibiting bacterial cell wall synthesis, making it valuable in combating various bacterial infections. Additionally, Ceftezole acts as an alpha-glucosidase inhibitor, demonstrating potential in in vivo anti-diabetic applications. It is suitable for use in microbiological research and studies related to diabetes management.
  10. Bacterial Inhibitor

    Ceftezole sodium is a broad-spectrum cephem antibiotic primarily targeting various gram-positive and gram-negative bacteria. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Additionally, ceftezole sodium demonstrates alpha-glucosidase inhibition, contributing to its in vivo anti-diabetic effects. This compound is relevant for research in microbial resistance and diabetes therapeutic development.
  11. Bacterial Inhibitor

    Sultamicillin tosylate is a broad-spectrum beta-lactamase inhibitor with potent antibacterial activity. This compound targets bacterial cell wall synthesis, making it effective against a variety of Gram-positive and Gram-negative bacteria. It is commonly used in microbiological research to study bacterial resistance mechanisms and to evaluate the efficacy of other antimicrobial agents.
  12. Bacterial Inhibitor

    Sultamicillin is a broad-spectrum beta-lactam antibiotic that functions primarily by inhibiting bacterial cell wall synthesis. It exhibits significant antibacterial activity against a variety of gram-positive and gram-negative bacteria. This compound is utilized in research applications focused on investigating bacterial resistance mechanisms and evaluating the efficacy of antibiotic treatments.
  13. Bacterial Inhibitor

    Clindamycin hydrochloride monohydrate is a bacterial inhibitor primarily targeting protein synthesis by binding to the 50S ribosomal subunit. This compound effectively suppresses the expression of virulence factors in Staphylococcus aureus, even at sub-inhibitory concentrations. Clindamycin hydrochloride monohydrate notably decreases the production of key toxins, including Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), and alpha-haemolysin (Hla), making it a valuable tool in microbiological research and the study of antibiotic resistance mechanisms.
  14. Bacterial Inhibitor

    Cefoperazone sodium salt is a semisynthetic cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative bacteria. This compound is widely utilized in microbiological research and clinical applications to study bacterial resistance and the efficacy of antibacterial therapies.
  15. Antibacterial Agent

    Cinnamyl acetate is an antibacterial agent that exhibits broad-spectrum activity against various bacterial strains. This compound is relevant in both pharmacological research and microbiological studies, providing insights into novel antibacterial formulations. Its unique properties make it a valuable tool for exploring antibacterial mechanisms and developing new therapeutic approaches.
  16. Bacterial Inhibitor

    Cefotiam hexetil hydrochloride is a prodrug of cefotiam, functioning primarily as a bacterial inhibitor. While it is designed for oral administration, this third-generation cephalosporin itself does not exhibit antibacterial activity until metabolized to cefotiam in the body. It is used in research applications to study antibiotic effects and efficacy in targeting gram-negative and gram-positive bacterial infections.
  17. Antibacterial Agent

    Phthalylsulfathiazole is an orally active sulfonamide that acts primarily as an antibacterial agent targeting intestinal pathogens. It exhibits low toxicity while demonstrating significant bacteriostatic activity against a range of bacteria, including E. coli, streptococci, and staphylococci, as well as total fecal bacteria. This compound is valuable for research applications focused on intestinal infections, including those related to colon infections, bacillary dysentery, and ulcerative colitis.
  18. Bacterial Inhibitor

    Ceftizoxime sodium is a third-generation cephalosporin antibiotic that functions as a bacterial inhibitor by binding to penicillin-binding proteins (PBPs). This action prevents bacterial cell wall synthesis, leading to cell lysis and death. It exhibits effectiveness against both Gram-negative and Gram-positive bacteria, making it valuable for research applications related to antibiotic resistance and bacterial infections.
  19. Antibacterial Agent

    Olanexidine hydrochloride semihydrate is an antibacterial agent with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It also possesses antiseptic properties, making it suitable for a variety of applications in infection and inflammation research. Researchers can utilize Olanexidine hydrochloride semihydrate to investigate microbial resistance mechanisms and develop new therapeutic strategies for bacterial infections.
  20. Bacterial Inhibitor

    Saccharin sodium hydrate functions as a bacterial inhibitor, exhibiting bacteriostatic properties. This compound modulates the microbiome and serves as a non-caloric artificial sweetener. It is applicable in research exploring bacterial growth inhibition and the effects of sweeteners on microbial populations.
  21. Antibacterial Agent

    6-Aminopenicillanic acid (6-APA) serves as a crucial precursor for the synthesis of β-lactam antibiotics and functions as an antibacterial agent. It disrupts bacterial cell wall synthesis during division, akin to penicillin, offering significant antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is primarily utilized in research focused on penicillin-related immune responses.
  22. Anti-Bacterial Agent

    Eravacycline dihydrochloride is a potent broad-spectrum antibacterial agent that targets bacterial protein synthesis by inhibiting the 30S ribosomal subunit. It exhibits significant activity against a range of Gram-positive and Gram-negative pathogens, including multidrug-resistant strains. This compound is widely used in research applications focused on exploring antibacterial resistance mechanisms and developing new therapeutic strategies.
  23. Bacterial Inhibitor

    (2S,5R,6R)-Ticarcillin disodium is a semisynthetic antibiotic that targets bacterial cell wall synthesis, exhibiting bactericidal activity. This compound serves as the (2S,5R,6R)-enantiomer of Ticarcillin, demonstrating efficacy against a broad range of Gram-negative bacteria. It is widely utilized in microbiological research for testing susceptibility and evaluating the mechanisms of antibiotic resistance.
  24. Bacterial Inhibitor

    Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound that serves as a bacterial inhibitor. It exhibits significant antimicrobial activity, making it effective in preventing plaque formation and reducing gingivitis. This compound is commonly utilized in oral care products, such as mouthwashes and toothpastes, as well as in throat and nasal sprays for its antiseptic properties.
  25. Bacterial Inhibitor

    Bacampicillin hydrochloride is a prodrug of ampicillin that acts as a bacterial inhibitor by disrupting cell wall synthesis in susceptible bacteria. It exhibits enhanced oral bioavailability compared to its parent compound, making it a valuable tool in studying bacterial infections and antibiotic resistance. This reagent is applicable in microbiological research and can facilitate investigations into the efficacy of penicillin derivatives in various laboratory settings.
  26. Antibacterial/Monocationic Surface-active Agent

    Thonzonium bromide is a monocationic surface-active agent with antibacterial properties. It demonstrates the ability to inhibit RANKL-induced osteoclast formation and bone resorption in vitro, while also preventing LPS-induced bone loss in vivo. Thonzonium bromide effectively inhibits proton transport in a dose-dependent manner, with an EC50 of 69 μM. This compound is valuable for research applications in bone health and antibacterial studies.
  27. Bacterial Inhibitor

    Benzalkonium chloride (51% in water) is a widely utilized bacterial inhibitor that acts by disrupting microbial cell membranes. This potent antimicrobial agent is commonly deployed in various applications, including as a preservative in ophthalmic formulations, such as eye drops. Its effectiveness against a broad spectrum of bacteria makes it an essential reagent for research and development in microbiology and pharmaceutical studies.
  28. Bacterial Inhibitor

    Isoniazid is a prodrug that targets the bacterial enzyme catalase-peroxidase (KatG) for activation, leading to its bactericidal effects against rapidly dividing mycobacteria. This compound exhibits significant anti-tuberculostatic activity and is widely used in research focused on tuberculosis and other mycobacterial infections. Its mechanism of action makes it a valuable reagent for investigating bacterial resistance and developing novel therapeutic strategies.
  29. Antibacterial Agent

    Kanamycin is an orally active antibacterial agent that targets both gram-negative and gram-positive bacteria by inhibiting translocation and causing misreading of mRNA. This aminoglycoside antibiotic demonstrates significant efficacy against Mycobacterium tuberculosis, including both sensitive and drug-resistant strains, as well as Klebsiella pneumoniae. Kanamycin is widely utilized in research applications focused on tuberculosis and pneumonia, providing valuable insights into bacterial infections and treatment strategies.
  30. Bacterial Inhibitor

    Ethambutol is an antimycobacterial agent that targets arabinosyltransferase, inhibiting cell wall synthesis in bacteria. This compound is primarily utilized in research related to mycobacterial infections and has applications in developing animal models for conditions such as hyperuricemia and optic neuropathy. Ethambutol's ability to interrupt bacterial growth makes it valuable for studying microbial pathogenesis and treatment strategies.
  31. Antibacterial Agent

    (Rac)-Moxifloxacin is an 8-methoxyquinolone antibiotic that targets bacterial DNA gyrase, disrupting DNA replication and transcription. This compound exhibits potent antibacterial activity against a wide range of gram-positive and gram-negative pathogens. It is primarily used in research settings to investigate bacterial infections, antibiotic resistance mechanisms, and potential therapeutic interventions for respiratory infections such as acute bacterial sinusitis and community-acquired pneumonia.
  32. Bacterial Inhibitor

    Puromycin is an aminoglycoside antibiotic that functions as a protein synthesis inhibitor through its action on bacterial ribosomes. By mimicking aminoacyl-tRNA, puromycin interferes with the elongation step of translation, leading to the premature termination of peptide chains. This compound is widely utilized in molecular biology studies, particularly in selection and maintenance of genetically modified cells, as well as in cancer research to elucidate apoptosis pathways.
  33. Bacterial Inhibitor

    3,5,4'-Tribromosalicylanilide is a bacterial inhibitor that exhibits potent antituberculosis activity. This compound effectively inhibits the growth of Mycobacterium tuberculosis and Mycobacterium abscessus, demonstrating its potential in combating mycobacterial infections. Additionally, it influences gene expression, suggesting its utility in research focused on antibiotic resistance and microbial gene regulation.
  34. Antibacterial Agent

    Sulfamerazine sodium salt is a sulfonamide antibiotic that targets bacterial dihydropteroate synthase, inhibiting folate synthesis essential for bacterial growth. This compound demonstrates effective antibacterial activity against a range of Gram-positive and Gram-negative pathogens. It is widely utilized in research for studying bacterial infections and the mechanisms of antibiotic resistance.
  35. Antibacterial Agents and Synergist

    Conimine is a steroidal alkaloid with significant antibacterial properties, specifically targeting bacteria such as methicillin-sensitive and methicillin-resistant Staphylococcus aureus. Isolated from the seeds of Holarrhena antidysenteriaca, Conimine not only exhibits intrinsic antibacterial activity but also acts as a potentiator. When used in combination with Penicillin or Vancomycin, Conimine enhances the antibacterial efficacy against both strains of Staphylococcus aureus, making it a valuable reagent for research in antibiotic synergy and resistance studies.
  36. Antibacterial Agent

    Glenthmycin E, an antibacterial agent derived from the Australian sheep pasture bacterium Streptomyces sp. CMB-PB041, exhibits inhibitory activity against a range of bacterial strains while demonstrating no detectable cytotoxicity to eukaryotic cells, including fungal and human carcinoma cells. This compound is pertinent for research focused on bacterial infections and offers potential applications in the development of novel antibacterial therapies.
  37. Antibacterial Agent

    Tolyl diiodomethyl sulfone is an organic antibacterial agent that targets bacterial infections. It exhibits significant antibacterial activity without adversely affecting fetal development, as evidenced by studies demonstrating no significant changes in the number of resorbed or dead fetuses, or in the body weight of live fetuses in rat models. This compound is suitable for research applications focusing on the evaluation of antibacterial efficacy and safety profiles in preclinical settings.
  38. Antibacterial agent

    Dimethoxane is an antibacterial agent targeting bacterial growth inhibition. It demonstrates a slow bactericidal effect against a variety of bacterial strains while exhibiting rapid bacteriostatic activity that prevents bacterial replication without causing cell lysis. Additionally, Dimethoxane has been investigated for its role in oncogenesis in animal models. It serves as a low-toxicity preservative in cosmetic applications and effectively controls microbial spoilage in aqueous formulations, emulsions, and suspensions.
  39. Antibacterial Agent

    Dipotassium phosphite functions as an antibacterial agent, targeting the development of Phytophthora infestans. This compound effectively reduces the severity of late blight in field-grown tomato plants, leading to improved overall productivity. Dipotassium phosphite is suitable for research focused on late blight management and plant disease resistance.
  40. Bacterial Inhibitor

    Benzoyleneurea is a bacterial inhibitor that demonstrates significant anti-bacterial activity. This compound serves as a valuable scaffold for the development of novel protein geranylgeranyltransferase-I (PGGTase-I) inhibitors, making it a useful tool in antibiotic research and drug discovery aimed at combating bacterial infections.
  41. Bacterial Inhibitor

    Tenuazonic acid is a mycotoxin belonging to the tetramic acids family, functioning primarily as an inhibitor of bacterial protein biosynthesis by promoting the suppression of new protein release on ribosomes. It exhibits acute toxicity, with oral LD50 values ranging between 81-186 mg/kg in rodents. Tenuazonic acid also acts as a photosystem II inhibitor by preventing electron transport beyond the primary quinone receptor (QA) through its interaction with the D1 protein. Furthermore, this compound has demonstrated antiviral activity against various viruses, including measles and respiratory viruses, and exhibits potential inhibitory effects on skin cancer.
  42. Antibacterial Agent

    Angustifoline, an alkaloid derived from Lupinus angustifolius L., functions as an antibacterial agent. This compound demonstrates significant antimicrobial activity, exhibiting bacteriostatic effects against a range of bacteria, including Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Bacillus thuringiensis. Angustifoline is valuable for research applications focusing on bacterial infections and the development of antibacterial treatments.
  43. Anti-Bacterial Agent

    Cephalosporin C is a β-lactam antibiotic primarily effective against Gram-positive and select Gram-negative bacteria. It exhibits stability to penicillinase, thereby enhancing its antimicrobial efficacy. The hydrolysis of Cephalosporin C allows for the production of 7-amino-cephalosporanic acid (7-ACA), a crucial precursor for the synthesis of semi-synthetic cephalosporins. This compound is widely utilized in the development of new antibacterial agents and in the study of antibiotic resistance mechanisms.

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