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Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Antistaphylococcal agent 3 is a bacterial inhibitor that targets Staphylococcus species, disrupting their growth and proliferation. This compound exhibits potent antimicrobial activity, making it suitable for research applications focused on bacterial infection models and therapeutic development. Its efficacy against resistant strains renders it valuable for studies aimed at understanding staphylococcal pathogenesis and developing novel antibacterial strategies. -
Bacterial Inhibitor
DS-8587 is a novel fluoroquinolone designed as a bacterial inhibitor, demonstrating significant antibacterial activity against amoxicillin-resistant Bacillus strains. Its minimum inhibitory concentration (MIC) values outperform those of ciprofloxacin and levofloxacin, while exhibiting reduced susceptibility to efflux pump-mediated resistance mechanisms such as adeA/adeB/adeC and abeM. Additionally, DS-8587 has a lower single-step mutation frequency compared to ciprofloxacin, positioning it as a promising therapeutic candidate for the treatment of amoxicillin-resistant Bacillus infections. -
Bacterial Inhibitor
Urechistachykinin I is a tachykinin-related peptide derived from echiuroid worms, primarily targeting bacterial pathogens. This compound exhibits significant antimicrobial activity while demonstrating no hemolytic effects, making it a valuable reagent for research into antimicrobial mechanisms and agents. Its unique properties make it suitable for studies investigating bacterial inhibition in various biological contexts. -
Bacterial Inhibitor
(Z)-Ligustilide acts as a bacterial inhibitor with demonstrated antimicrobial and antifungal properties. Extracted from Ligusticum chuanxiong Hort, it has shown an average antifungal score of 5.6. This compound inhibits the expression of FATP5 and DGAT, thereby reducing fatty acid uptake and esterification, positioning it as a potential therapeutic agent for nonalcoholic fatty liver disease (NAFLD). Additionally, (Z)-Ligustilide is involved in reactivating ERĪ± and exhibits epigenetic regulatory functions, making it relevant for research into tamoxifen-resistant breast cancer. -
Bacterial Inhibitor
Roseoflavin is a bacterial inhibitor, functioning as an antimetabolite analog of riboflavin and flavin mononucleotide. This natural pigment, originally extracted from Streptomyces davawensis, exhibits potent antimicrobial properties. It is commonly utilized in research applications aimed at studying bacterial metabolism and the mechanisms of antibiotic resistance. -
Bacterial Inhibitor
Poly-L-lysine hydrochloride is a cationic polymer that functions as a bacterial inhibitor by enhancing cell adhesion through electrostatic interactions with negatively charged cell membranes. It promotes liquid-liquid phase separation (LLPS) at low concentrations while inhibiting LLPS at elevated concentrations, making it a versatile tool for cell culture applications. This reagent is particularly useful in studies involving bacterial attachment mechanisms and cell substrate interactions. -
Bacterial Riboflavin Riboswitches Inhibitor
Ribocil-C is a potent inhibitor of bacterial riboflavin riboswitches, targeting their regulatory mechanism to disrupt riboflavin biosynthesis. This compound exhibits a high degree of selectivity and is valuable for studying riboswitch function and its role in bacterial gene regulation. Ribocil-C is applicable in research focusing on microbial metabolism and the development of antibacterial strategies. -
Bacterial Inhibitor
Lymecycline is a tetracycline derivative known for its mechanism as a bacterial inhibitor. It exhibits broad-spectrum antibacterial activity, making it effective against a variety of bacterial infections. Additionally, Lymecycline possesses anti-inflammatory properties, which may be beneficial in treating conditions where inflammation plays a significant role. Its applications in research include studying bacterial resistance mechanisms and exploring its therapeutic potential in inflammatory diseases. -
Bacterial Inhibitor
Procyanidin A2 is a flavonoid with documented antibacterial properties. It exhibits significant antimicrobial activity, making it a valuable compound for research into bacterial inhibition and potential therapeutic applications. Additionally, Procyanidin A2 possesses antioxidant and anti-inflammatory effects, further supporting its relevance in studies focused on cancer and inflammatory diseases. -
Bacterial Inhibitor
Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis that primarily targets bacterial pathogens. It exhibits significant anti-inflammatory and antimicrobial properties, demonstrating potent efficacy against Mycobacterium aurum and Mycobacterium bovis BCG. This compound is valuable for research focused on osteoclast differentiation, survival, and function as well as the development of novel antibacterial therapies. -
Bacterial Inhibitor
Acetylalkannin is an isohexenylnaphthazarin pigment derived from Arnebia euchroma, primarily known for its bacterial inhibitory properties. This compound exhibits significant antimicrobial and cytotoxic activities, making it valuable for research in antibacterial drug development and cell viability studies. Its unique structure and biological efficacy provide a useful tool for investigating microbial interactions and potential therapeutic applications. -
Bacterial Inhibitor
4-Hydroxycoumarin is a versatile coumarin derivative that acts as a bacterial inhibitor. It demonstrates both electrophilic and nucleophilic properties, making it a valuable scaffold in organic synthesis. This compound exhibits significant biological activities, including anti-inflammatory, antibacterial, and anti-tumor effects, and has been utilized in research focusing on HIV protease and tyrosine kinase inhibition. Its multifaceted applications make it an important reagent in chemical and biological research. -
Bacterial Inhibitor
Furanone C-30 is a potent quorum sensing inhibitor that targets bacterial communication systems. It effectively disrupts biofilm formation in Streptococcus mutans, including its luxS mutant strain. This compound is valuable for research applications focused on bacterial pathogenesis and biofilm-related studies, providing insights into microbial interactions and potential therapeutic strategies against bacterial infections. -
Bacterial Inhibitor/Anti-inflammatory Agent
Cyclo(L-Pro-L-Val) is a peptide-based compound that functions as a bacterial inhibitor and anti-inflammatory agent. It exhibits antimicrobial activity against plant pathogens, such as R. fascians, and demonstrates significant inhibition of critical signaling molecules like IKKĪ±, IKKĪ², NF-ĪŗB, iNOS, and COX-2, contributing to its anti-inflammatory properties. This compound is valuable for research applications in developing biopesticides and investigating inflammation-related diseases. -
Bacterial Inhibitor
N-Acetyltyramine is a quorum-sensing inhibitor (QSI) produced by Vibrio alginolyticus M3-10. It effectively inhibits the quorum-sensing processes of Chromobacterium violaceum ATCC 12472, showing promise in modulating bacterial communication. Additionally, N-acetyltyramine has demonstrated the potential to reverse resistance in Doxorubicin-resistant leukemia P388 cells, making it a valuable tool for studying antibiotic resistance and leukemic cell sensitivity. -
Bacterial Inhibitor
Isoastilbin is a dihydroflavonol glycoside that acts primarily as a bacterial inhibitor. It effectively inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 Ī¼g/mL and also shows inhibitory effects on tyrosinase activity. This compound demonstrates neuroprotective, antioxidant, antimicrobial, and anti-apoptotic properties, making it valuable for research applications related to Alzheimer's disease and other neurodegenerative conditions. -
Bacterial Inhibitor
G0507 is a pyrrolopyrimidinedione compound that acts as a potent inhibitor of the LolCDE ABC transporter in Gram-negative bacteria. By selectively inhibiting Escherichia coli growth, G0507 triggers the extracytoplasmic ĻE stress response, making it a valuable tool for studying lipoprotein trafficking. This compound serves as a chemical probe in bacterial research, offering insights into the mechanisms of antibiotic resistance and bacterial physiology. -
Bacterial Inhibitor
25-NBD Cholesterol is a fluorescently labeled cholesterol derivative that targets bacterial cell membranes. It significantly enhances the visualization and distinction between exogenous and endogenous cholesterol, emitting green fluorescence signals. This reagent is valuable for studies focused on lipid metabolism, membrane dynamics, and bacterial inhibition, promoting a deeper understanding of cholesterol's role in bacterial physiology. -
Bacterial Inhibitor
LCC-12 formic is a dimer of metformin that acts as a bacterial inhibitor through its interaction with mitochondrial copper(II), resulting in a reduction of the NAD(H) pool and modulation of inflammatory responses. This compound has demonstrated the ability to decrease inflammation in mouse models of bacterial and viral infections. Additionally, LCC-12 formic is utilized as a research tool to explore metabolic diseases, focusing on its impact on cell plasticity and epigenetic programming. -
Bacterial Inhibitor
Human milk lysozyme is an enzyme that specifically targets bacterial cell walls, functioning as a crucial antibacterial agent. It exhibits significant antimicrobial activity against a variety of Gram-positive and Gram-negative bacteria, contributing to the protective immunity of neonates. This reagent is used in research applications focused on infant gut health, nutritional science, and the development of therapeutic strategies to combat bacterial infections. -
Bacterial Inhibitor
MBX-4132 is an oxadiazole compound that functions as a bacterial inhibitor by targeting and binding to the bacterial ribosome, specifically inhibiting trans translation. This selective action disrupts protein synthesis in bacteria, making it a valuable tool for research into antibiotic mechanisms and the development of new antibacterial agents. Its use in various microbiological studies provides insights into ribosomal function and the impacts of translational inhibition on bacterial growth and survival. -
Bacterial Inhibitor
Daphnin is a bioactive coumarin compound that acts as an antibacterial agent. Isolated from the whole herb of Daphne odora, Daphnin has demonstrated significant efficacy in inhibiting bacterial growth. This compound is of particular interest in research applications focused on natural product pharmacology and the development of alternative antibacterial therapies. -
Bacterial Inhibitor
Fraxidin is a coumarin derivative derived from the roots of Jatropha podagrica, demonstrating significant antibacterial activity against Bacillus subtilis. At a concentration of 20 Āµg/disk, Fraxidin produces an inhibition zone measuring 12 mm. This compound is valuable for research applications focusing on antibacterial mechanisms and the development of new antimicrobial agents. -
Bacterial Inhibitor
Macranthoside B is a bacterial inhibitor obtained from Flos Lonicerae. It exhibits significant antibacterial activity, making it a valuable tool for research in the study of bacterial infections and the development of novel antimicrobial agents. Its properties can contribute to investigations on bacterial resistance and the search for effective therapeutic strategies. -
Bacterial Inhibitor
Licoflavonol is a minor flavone derived from the roots of Glycyrrhiza uralensis, functioning as an inhibitor of the Salmonella type III secretion system (T3SS). This compound exhibits notable antibacterial activity, making it a valuable tool for researching Salmonella pathogenesis and the mechanisms of bacterial infection. Its targeted inhibition of T3SS offers potential applications in the development of antimicrobial strategies and the study of host-pathogen interactions. -
Bacterial Inhibitor
Glucuronic acid sodium functions primarily as a bacterial inhibitor, demonstrating notable anti-inflammatory properties. It supports the healing of ulcerative colitis by enhancing the intestinal barrier through the upregulation of tight junction proteins such as ZO-1 and Occludin. Additionally, Glucuronic acid sodium modulates gut microbiota composition by promoting beneficial bacterial populations while inhibiting pathogenic microbes, making it a valuable tool for research in gastrointestinal health and microbiome studies. -
Bacterial Inhibitor
Pinocembrin chalcone, known as 2',4',6'-Trihydroxychalcone, is a bacterial inhibitor derived from Helichrysum trilineatum. It activates AMP-activated protein kinase (AMPK), enhancing glucose tolerance while promoting fatty acid oxidation and reducing fat accumulation in the liver and skeletal muscles of high-fat diet-induced diabetic mice. This compound shows potential for research applications in gastric ulcer and diabetes studies, contributing to the understanding of metabolic regulation and bacterial infections. -
Bacterial Inhibitor
Guaijaverin is a bacterial inhibitor that functions as a urease inhibitor with an IC50 of 120 Ī¼M. Demonstrating antioxidant properties, it exhibits significant anti-Streptococcus mutans activity. This compound is valuable for research focused on bacterial inhibition and potential therapeutic applications in treating infections caused by Streptococcus species. -
Bacterial Inhibitor
Medicagenic acid, a potent bacterial inhibitor derived from the roots of Herniaria glabra, demonstrates significant fungistatic activity against various plant pathogens and human dermatophytes. This compound exhibits low enzyme inhibitory activity, specifically targeting xanthine oxidase, collagenase, elastase, tyrosinase, and cholinesterase. Medicagenic acid is valuable for research applications in studying antifungal resistance mechanisms and exploring potential therapeutic avenues for dermatological conditions. -
Bacterial Inhibitor
Tosylchloramide sodium trihydrate is a bacterial inhibitor that acts as a potent disinfectant. This reagent exhibits broad-spectrum antimicrobial activity, making it suitable for applications in laboratories, healthcare settings, and sanitation in commercial environments. Additionally, Tosylchloramide sodium trihydrate serves as a biocide in personal care products, including air fresheners and deodorants. -
Bacterial Inhibitor
Tolclofos-methyl is a bacterial inhibitor that functions as a broad-spectrum aromatic hydrocarbon fungicide. It exhibits potent activity against soil-borne and seed-borne fungal pathogens, effectively preventing seed decay and seedling blights. This compound is valuable in agricultural research for its ability to enhance seed treatment efficacy and promote plant health by mitigating fungal diseases. -
Bacterial Inhibitor
Fumagillol is a bacterial inhibitor with a primary role as a precursor to fumagillin. It exhibits significant antimicrobial activity and selectively inhibits angiogenesis, making it a valuable reagent for research in vascular biology and microbial pathology. Its utility extends to studies focused on the mechanisms of angiogenesis and the development of novel therapeutic strategies against microbial infections. -
Bacterial Inhibitor
Olanexidine hydrochloride is a monobiguanide compound with potent bactericidal activity, targeting bacterial cell membranes to disrupt membrane integrity. It demonstrates efficacy against a broad spectrum of both Gram-positive and Gram-negative bacteria. Notably, Olanexidine exhibits a bactericidal concentration of 109 Ī¼g/mL for Gram-positive bacilli, making it valuable in microbiological research and applications involving antimicrobial susceptibility testing. -
Bacterial Inhibitor
RPW-24 is a bacterial inhibitor that enhances the immune response of Caenorhabditis elegans, providing protection against bacterial infections. This compound demonstrates significant antibacterial activity, making it a valuable tool for studying host-pathogen interactions and immune modulation in nematodes. RPW-24 is applicable in research focusing on innate immunity and antimicrobial strategies in model organisms. -
Bacterial Inhibitor
(Ā±)-Leucine, also known as DL-Leucine, is a stereoisomer of the amino acid leucine that acts as a bacterial growth inhibitor. It demonstrates significant antibacterial activity, inhibiting the growth of Escherichia coli HfrH by 92.08%. This compound is utilized in biochemical research for its potential applications in microbial control and as a dietary additive in various studies. -
Bacterial Inhibitor
Hetacillin is a beta-lactam antibiotic that acts primarily by inhibiting bacterial cell wall synthesis. As a member of the aminopenicillin family, it is effective against a variety of gram-positive and some gram-negative bacteria. This reagent is commonly utilized in microbiological studies and antibiotic susceptibility testing, making it valuable for research on bacterial infections and resistance mechanisms. -
Bacterial Ī²-glucuronidase Inhibitor
UNC10201652 is a potent inhibitor of bacterial Ī²-glucuronidase, specifically targeting Loop 1 (L1) in gut microbiota, with an IC50 value of 0.117 Ī¼M for E. coli Ī²-glucuronidase. This compound effectively blocks the processing of SN-38 glucuronide, predominantly in individuals with a high abundance of L1 GUS enzymes in their fecal microbiota. Its application is of particular interest in studying gut microbiome interactions and drug metabolism. -
Bacterial Inhibitor
3-O-Methylgalangin is a natural flavonoid derived from the rhizome of Alpinia officinarum, exhibiting significant antibacterial activity. This compound acts as a bacterial inhibitor and is also known to inhibit pancreatic lipase. Its properties make it a valuable tool for research in microbiology and metabolic studies. -
Bacterial Inhibitor
Nonacosane is a naturally occurring alkane derived from Baphia massaiensis, with demonstrated antibacterial activity. It exhibits weak inhibitory effects against various bacterial strains, including Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus. This compound can be utilized in research focused on bacterial resistance and the development of antibacterial agents. -
Bacterial Inhibitor
5-Desmethylsinensetin is a bacterial inhibitor derived from Artemisia princeps. This compound exhibits significant antiprotozoal activity, demonstrating IC50 values of 0.4 Ī¼g/mL against T. cruzi epimastigotes and 75.1 Ī¼g/mL against trypomastigotes. It serves as a valuable tool for research into protozoan infections and potential therapeutic applications. -
Bacterial Inhibitor
Salannin is a limonoid compound derived from the seed oil of Azadirachta indica, acting primarily as a bacterial inhibitor. It exhibits significant antibacterial activity against both Gram-positive and Gram-negative bacteria, making it a valuable reagent in microbiological research. Additionally, Salannin demonstrates antiulcer and spermicidal properties, supporting its potential applications in pharmacological studies and therapeutic development. -
Bacterial Inhibitor
2-Mercaptopyridine N-oxide sodium is a bacterial inhibitor targeting Mycobacterium tuberculosis. It exhibits a bactericidal effect with a minimum inhibitory concentration (MIC90) of 7.20 Ī¼M against the standard strain H37Rv (ATCC 27294). This compound, along with its complexes with iron, gallium, and bismuth, demonstrates promising anti-tuberculosis activity, indicating its potential utility in the treatment of tuberculosis. -
Bacterial Inhibitor
4-Ethoxyphenol is a natural bacterial inhibitor derived from the marine gorgonian-associated bacterium Bacillus amyloliquefaciens SCSIO 00856. This compound exhibits significant antilarval activity, demonstrating an EC50 value of 24.1 Ī¼g/mL against Bacillus amphitrite larvae. Its properties make it a valuable tool for research applications in microbiology and biopesticide development. -
Bacterial Inhibitor
Rubrofusarin is a polyketide pigment derived from Fusarium graminearum, known for its antibacterial properties. This compound exhibits significant biological activity, including anticancer and antioxidant effects, and has been shown to alleviate depressive symptoms induced by chronic restraint stress through the PI3K/Akt signaling pathway. Rubrofusarin serves as a valuable tool in research applications focused on bacterial inhibition and the exploration of therapeutic strategies for stress-related disorders. -
Bacterial Inhibitor
N-Butanoyl-DL-homoserine lactone (Rac-C4-HSL) functions as a bacterial inhibitor by interfering with quorum sensing mechanisms. This racemic mixture includes both N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone, the latter being significant in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone exhibits antibacterial activity by inhibiting biofilm formation, particularly in Pseudomonas aeruginosa, making it valuable for research in bacterial communication and biofilm-related studies. -
Bacterial Inhibitor
JPD447 is a potent inhibitor of the enzyme UppS, which plays a critical role in bacterial cell wall biosynthesis. By targeting this enzyme, JPD447 enhances the efficacy of Ī²-lactam antibiotics, making it a valuable tool in combatting bacterial infections. Its application in research focuses on understanding antibiotic resistance mechanisms and improving antibiotic therapeutic strategies. -
Bacterial Inhibitor
4-Chloroquinaldine is a bacterial inhibitor that targets various bacterial species, demonstrating significant antibacterial activity. This compound serves as an important intermediate in chemical synthesis and research applications aimed at exploring antibiotic development and mechanisms of bacterial resistance. Its utility in microbiological studies makes it a valuable reagent for researchers in the field. -
Bacterial Inhibitor
Picloxydine is a heterocyclic biguanide that serves as a bacterial inhibitor. It exhibits significant antibacterial and antiplaque activity, making it useful in various research applications aimed at understanding microbial growth and infection control. This compound can be applied in studies related to dental hygiene and the prevention of bacterial biofilms. -
Bacterial Inhibitor
LolCDE-IN-2 is a potent inhibitor of the LolCDE protein complex, targeting bacterial lipid transport. It demonstrates significant antibacterial activity against E. coli MG1655, with a minimum inhibitory concentration (MIC) of 2 Ī¼g/ml. This compound is valuable for research applications focused on bacterial pathogenesis and antibiotic resistance mechanisms. -
Bacterial Inhibitor
Enterocin K1 is a ribosomally synthesized peptide that functions as a bacteriocin, specifically targeting Enterococcus faecalis through the Eep protein on the bacterial membrane. This compound exhibits significant antibacterial activity against vancomycin-resistant Enterococcus (VRE). Enterocin K1 is primarily utilized in research focusing on VRE infections and the mechanisms of microbial resistance, making it a valuable tool in the development of novel therapeutic strategies.
