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Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Lactoferrin (17-41) acetate is a peptide derived from residues 17-41 of bovine lactoferrin, primarily functioning as a bacterial inhibitor. It exhibits potent antimicrobial activity against various microorganisms, including Gram-positive and Gram-negative bacteria, viruses, protozoa, and fungi. In addition to its antimicrobial properties, Lactoferrin (17-41) acetate also demonstrates antitumor activities, making it a valuable reagent in studies related to infection control and cancer research. -
Bacterial Transcription Inhibitor
GKL003 is a bacterial transcription inhibitor that targets the interaction interface of RNA polymerase (RNAP) and the sigma factor, with a Ki value of 5.79 nM. By specifically binding to the RNAP β' clamp helix region at the σA factor binding site, GKL003 disrupts the formation of the RNAP holoenzyme and inhibits bacterial transcription initiation complexes. This compound effectively inhibits the growth of both Gram-positive and Gram-negative bacterial strains, including those that are drug-resistant, making it a valuable tool for research applications in microbiology and antibiotic resistance studies. -
Bacterial Inhibitor
Mequindox is an antimicrobial agent that functions as a bacterial inhibitor by selectively targeting and inhibiting DNA synthesis. This compound demonstrates significant genotoxic and carcinogenic effects in murine models, making it a valuable tool for studying bacterial resistance mechanisms and the potential impacts of antimicrobial agents on genetic material. Its applications extend to research on the safety and efficacy of antimicrobial treatments in various biological systems. -
Bacterial Inhibitor
Silver sulfadiazine is a sulfonamide antibiotic that functions as a bacterial inhibitor through dual mechanisms. The sulfa moiety inhibits bacterial folate absorption, thereby disrupting essential DNA synthesis. Additionally, silver ions released from silver sulfadiazine bind to and disrupt DNA structures, preventing bacterial DNA replication. This compound is widely used in research applications focusing on bacterial growth inhibition and antimicrobial studies. -
Bacterial Inhibitor
Fenvalerate is a highly effective bacterial inhibitor, primarily functioning as a protein phosphatase 2B (calcineurin) inhibitor, with an IC50 of 2-4 nM for PP2B-Aα. As a pyrethroid ester, it exhibits significant insecticidal and acaricidal properties. This compound is utilized in various research applications to study protein phosphatase signaling pathways and to explore potential therapeutic targets in bacterial infections. -
Bacterial Inhibitor
(Z)-Methyl tetradec-9-enoate functions as a bacterial inhibitor, primarily exerting its cytotoxic effects in human prostate cancer LNCaP cells through the induction of apoptosis and necrosis. Isolated from S. repens fruit extract, this compound also demonstrates antifungal activity, effectively inhibiting the germination of Candida albicans with a minimum inhibitory concentration (MIC) of 9 μM in vivo. Its applications extend to studies in both cancer research and microbiology, making it a valuable reagent for understanding cellular processes and developing therapeutic strategies. -
Antibacterial Agent/eEF2K Inhibitor
Cefatrizine is a broad-spectrum cephalosporin antibiotic that primarily targets bacterial infections while also acting as an eEF2K inhibitor. This compound exhibits anti-proliferative activity in human breast cancer cells, inducing endoplasmic reticulum stress and subsequent cell death. Cefatrizine is a valuable reagent for research applications in understanding mechanisms of cancer therapy and exploring antibacterial efficacy. -
Bacterial DNA Gyrase/Topo IV Inhibitor
GC-072 is a selective inhibitor of bacterial DNA gyrase and Topoisomerase IV, demonstrating potent antibacterial activity. This 4-oxoquinolizine antibiotic exhibits efficacy against a wide range of bacterial strains, including Gram-positive, Gram-negative, and multidrug-resistant organisms. Importantly, GC-072 does not interfere with human topoisomerases I and II, making it a suitable candidate for studying bacterial infections. Its bactericidal action against Burkholderia pseudomallei is significant, as it supports dose-dependent survival rates in mice during lethal inhalational models, highlighting its potential in melioidosis research. -
Bacterial DNA Gyrase B Inhibitor
DNA Gyrase-IN-3 is a specific inhibitor of bacterial DNA gyrase B, exhibiting IC50 values ranging from 5.41 to 15.64 µM against E. coli DNA gyrase. This compound demonstrates significant anti-tubercular and antibacterial activity, making it a valuable tool for microbial research. Its mechanism of action is relevant in studies aimed at developing new antibacterial agents targeting bacterial DNA replication and transcription processes. -
Bacterial Inhibitor
CI-990 (PD-131112) is a selective inhibitor of bacterial DNA gyrase, targeting key enzymes involved in DNA replication and repair. It exhibits potent antibacterial activity and is especially relevant for studying Enterococcal infections, including endocarditis and sepsis. This compound can serve as a valuable tool in microbiological research to understand bacterial resistance mechanisms and develop therapeutic strategies. -
Bacterial Transcription Inhibitor
CUHK242 is a selective bacterial transcription inhibitor that effectively disrupts RNA synthesis within bacterial cells. It demonstrates a minimum inhibitory concentration (MIC) of 2 μg/mL against the B. subtilis reporter strain BS2019 and exhibits antimicrobial activity against Staphylococcus aureus. This compound is useful for research applications focused on understanding bacterial gene expression and studying the mechanisms of antibiotic resistance. -
Bacterial DNA Gyrase B Inhibitor
DNA Gyrase-IN-2 is a potent inhibitor of bacterial DNA gyrase B, demonstrating IC50 values of 3.29-10.49 µM for Escherichia coli and 4.41-5.61 µM for Mycobacterium tuberculosis. This compound exhibits significant anti-tubercular and antibacterial activity, making it valuable for research focused on bacterial replication and antibiotic development. Its specific targeting of DNA gyrase B positions it as a promising candidate for further investigation in treating bacterial infections. -
Bacterial Inhibitor
Ethionamide is a second-line anti-tuberculosis agent that acts primarily by inhibiting the synthesis of mycolic acids in Mycobacterium tuberculosis. This compound demonstrates significant antibacterial activity and is effective when administered orally. Ethionamide is utilized in research applications focused on tuberculosis treatment resistance mechanisms and the development of novel therapeutics against mycobacterial infections. -
Bacterial Inhibitor
Fleroxacin is a broad-spectrum fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication and transcription. This compound exhibits potent antibacterial activity against a wide range of gram-negative and some gram-positive bacteria. Fleroxacin is suitable for research applications focused on the elucidation of bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
Bacterial Inhibitor
Nitrofurazone is a nitro-aromatic antibacterial compound primarily targeting bacterial DNA and RNA synthesis. It exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria, making it suitable for a variety of microbiological research applications. Nitrofurazone is often utilized in studies assessing antimicrobial resistance and the efficacy of antibiotic treatments. -
Bacterial Inhibitor
Teicoplanin is a glycopeptide antibiotic primarily targeting Gram-positive bacteria, demonstrating potent activity against methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus aureus. In addition to its antibacterial properties, teicoplanin exhibits antiviral effects against HIV-1, SARS-CoV-1, and SARS-CoV-2. This versatile compound is utilized in research related to bacterial resistance and viral infections, making it a valuable tool for studying antimicrobial efficacy and therapeutic interventions. -
Bacterial Inhibitor
Tobramycin is a broad-spectrum aminoglycoside antibiotic that primarily targets bacterial protein synthesis by binding to the 30S ribosomal subunit. It exhibits significant antibacterial activity against a variety of Gram-negative and some Gram-positive bacteria. Tobramycin is particularly effective in research applications focused on infections caused by Pseudomonas aeruginosa, including studies related to pneumonia. Its efficacy makes it a valuable reagent in microbial pathogenesis and antibiotic resistance research. -
Bacterial Inhibitor
Ampicillin sodium is a broad-spectrum beta-lactam antibiotic that targets bacterial cell wall synthesis. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable reagent for microbiological research. Ampicillin sodium is commonly used in cell culture and for selecting genetically modified organisms, as well as in the study of bacterial resistance mechanisms. Its ability to inhibit bacterial growth supports investigations into antibiotic efficacy and microbial interactions. -
Bacterial Inhibitor
Cefoperazone is a semisynthetic cephalosporin that functions as a bacterial inhibitor by interfering with cell wall synthesis. It exhibits a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative bacteria. This reagent is commonly employed in microbiological research to study bacterial infections and assess the efficacy of antimicrobial agents. -
Bacterial Inhibitor
Erdosteine functions as a bacterial inhibitor by inhibiting lipopolysaccharide (LPS)-induced activation of NF-κB. This compound exhibits muco-modulatory, anti-bacterial, anti-inflammatory, and antioxidant properties. Erdosteine is primarily utilized in research applications focused on respiratory disorders and inflammation, supporting the study of therapeutic interventions in these areas. -
Bacterial Inhibitor
Erianin is a bacterial inhibitor that exhibits potent anticancer properties by inhibiting indoleamine 2,3-dioxygenase (IDO). This activity contributes to its ability to suppress tumor angiogenesis, making it a valuable compound in cancer research. Erianin's dual role as an antipyretic and analgesic further broadens its potential applications in therapeutic studies. -
Bacterial Inhibitor
Allicin (diallyl thiosulfinate) is a potent bacterial inhibitor derived from garlic extracts, primarily responsible for the antimicrobial properties of garlic. It demonstrates significant antimicrobial activity against a wide range of microorganisms, including antibiotic-resistant strains, making it a valuable reagent for research in microbiology and pharmacology. Allicin is commonly utilized in studies investigating natural antibacterial compounds and their mechanisms of action. -
Bacterial Inhibitor
Evoxine, also known as Haplophytin B, is a bacterial inhibitor that selectively targets CO2-induced immunosuppression. It demonstrates significant antimicrobial activity, particularly against common pathogens such as Escherichia coli, Bacillus subtilis, and Staphylococcus aureus, as evidenced by its performance in minimum inhibitory concentration (MIC) assays. Evoxine also inhibits the expression of pro-inflammatory cytokines such as interleukin-6 and chemokine CCL2 in human THP-1 macrophages, indicating its potential utility in therapeutic applications and crude drug preparations, particularly in the context of traditional medicine in West Africa. -
Bacterial Inhibitor
3,3'-Di-O-methylellagic acid is a bacterial inhibitor derived from Euphorbia adenochlora. It selectively inhibits the development of acid-fastness in mycobacteria without affecting their growth rates. Additionally, this compound exhibits hepatoprotective properties, likely attributed to its antioxidative effects, making it valuable for research in microbial resistance and liver health. -
Bacterial Inhibitor
Methyl Paraben is a bacterial inhibitor primarily used as a preservative in various applications due to its stability and non-volatility. It has been shown to enhance histamine release and modulate cellular immune responses, in addition to blocking sodium channels. Its properties make it valuable for studies exploring microbial inhibition and the mechanisms of ischemia-reperfusion injury. -
Bacterial Inhibitor
Enrofloxacin is a potent bacterial inhibitor belonging to the fluoroquinolone class. It exhibits an MIC90 value of 0.312 μg/mL against Mycoplasma bovis, demonstrating its effectiveness in combating bacterial infections. This compound is widely utilized in research applications focused on antibiotic resistance, microbiology, and the study of bacterial pathogens. -
Bacterial Inhibitor
Florfenicol is a broad-spectrum antibacterial agent that exerts its effects primarily through inhibition of bacterial protein synthesis. This orally active compound demonstrates additional properties, including anti-inflammatory, pro-apoptotic, and immunomodulatory functions. Florfenicol is commonly utilized in research focused on bacterial infections and the modulation of immune responses. -
Bacterial Inhibitor
Furaltadone hydrochloride is an orally active antibacterial agent targeting bacterial infections. It exhibits in vitro inhibitory effects on Staphylococcus and can be utilized in the study of intestinal Salmonella infections. Additionally, Furaltadone demonstrates potential inhibitory effects on allergic reactions, making it a valuable tool for research in microbiology and immunology. -
Bacterial Inhibitor
Penicillin G sodium salt is a β-lactam antibiotic that inhibits bacterial cell wall synthesis by targeting penicillin-binding proteins. It demonstrates broad-spectrum antibacterial activity against various Gram-positive and some Gram-negative organisms. This reagent is commonly used in microbiological studies to evaluate susceptibility patterns and in the development of antibiotic resistance models. -
Bacterial Inhibitor
Piperacillin sodium is a semisynthetic β-lactam antibiotic that targets penicillin-binding proteins, exhibiting potent bactericidal activity against a broad range of Gram-negative bacteria and select Gram-positive strains. This compound is widely utilized in pharmaceutical research to study bacterial infections and antibiotic resistance. Piperacillin sodium is frequently employed in combination with the β-lactamase inhibitor Tazobactam to enhance its efficacy against resistant bacterial strains. -
Bacterial Inhibitor
Ribostamycin sulfate is a broad-spectrum bacterial inhibitor that targets protein synthesis by binding to the 30S and 50S ribosomal subunits. Additionally, it inhibits the chaperone activity of protein disulfide isomerase (PDI). This reagent is primarily utilized in pharmacokinetic studies and investigations of nephrotoxicity, making it valuable in the evaluation of antimicrobial efficacy and safety profiles. -
Bacterial Inhibitor
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic that targets bacterial protein synthesis. It exhibits strong antibacterial activity, particularly against Gram-positive bacteria, making it an effective choice in studies of bacterial inhibition. This compound is useful for research applications involving the characterization of bacterial resistance and the development of new antimicrobial strategies. -
Bacterial Inhibitor
Sodium 4-aminosalicylate dihydrate serves as an inhibitor of dihydrofolate reductase (DHFR) and is recognized for its antituberculous properties. This compound exhibits anti-inflammatory effects, making it a valuable tool in the study of inflammatory bowel disease (IBD). Moreover, it is characterized by its oral bioavailability, enhancing its applicability in various research settings. -
Bacterial Inhibitor
Sparfloxacin is a fluoroquinolone antibiotic that primarily targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication. It exhibits broad-spectrum antibacterial activity, making it effective against a variety of Gram-positive and Gram-negative pathogens. Sparfloxacin is commonly used in research applications to study bacterial resistance mechanisms and evaluate new antibacterial strategies. -
Bacterial Inhibitor
Streptomycin sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. It exhibits potent antibacterial activity against a range of Gram-negative and some Gram-positive bacteria, making it useful in both clinical and research settings. This reagent is commonly employed in studies involving microbial resistance, antibiotic efficacy, and protein synthesis mechanisms. -
Bacterial Inhibitor
Sulfamethazine is an antimicrobial agent that acts as a bacterial inhibitor, demonstrating permeability across the blood-brain barrier. It is commonly utilized in veterinary medicine to treat and prevent a variety of animal diseases, including gastrointestinal and respiratory tract infections. Regulatory standards set by China and the European Commission establish a maximum residue level of 100 μg/kg for Sulfamethazine in animal products, underscoring its significance in both therapeutic and safety assessments. -
Bacterial Inhibitor
Urethane, also known as ethyl carbamate, is an ethyl ester of carbamic acid that acts as a bacterial inhibitor. It demonstrates the ability to suppress the growth of bacteria, protozoa, sea urchin eggs, and plant tissues in vitro. This compound is primarily utilized in studies examining microbial inhibition and growth regulation in various biological systems. -
Bacterial Inhibitor
Carbadox is a quinoxaline-di-N-oxide antibiotic that functions as a bacterial inhibitor. It is primarily used in veterinary medicine to control enteric infections in nursery-age pigs, enhancing feed efficiency and promoting overall health. Its antibacterial properties make it valuable for research applications focused on veterinary pharmacology and microbiology in the study of antibiotic efficacy and resistance mechanisms. -
Bacterial Inhibitor
Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic that acts as a bacterial inhibitor through the inhibition of protein synthesis. It exhibits broad-spectrum antibacterial activity, making it effective against various skin infections, including acne vulgaris. This reagent is valuable for research into antibiotic resistance and the mechanisms of bacterial infection. -
Bacterial Inhibitor
Saccharin is a non-caloric artificial sweetener that primarily exhibits bacteriostatic properties. It is recognized for its ability to inhibit bacterial growth and modulate the microbiome. This compound is utilized in various research applications aimed at studying microbial dynamics and the effects of sweeteners on bacterial populations. -
Bacterial Inhibitor
Octenidine dihydrochloride is a potent bacterial inhibitor that functions as an antiseptic. Its primary mechanism involves disrupting microbial cell membranes, which results in effective antimicrobial activity against a broad spectrum of pathogens. This compound is widely utilized in medical and clinical research for its applications in wound care, skin disinfection, and maintaining sterile conditions in various settings. -
Bacterial Inhibitor
Ceftezole is a broad-spectrum cephem antibiotic that effectively targets both gram-positive and gram-negative bacteria. Its primary mechanism involves inhibiting bacterial cell wall synthesis, making it valuable in combating various bacterial infections. Additionally, Ceftezole acts as an alpha-glucosidase inhibitor, demonstrating potential in in vivo anti-diabetic applications. It is suitable for use in microbiological research and studies related to diabetes management. -
Bacterial Inhibitor
Ceftezole sodium is a broad-spectrum cephem antibiotic primarily targeting various gram-positive and gram-negative bacteria. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Additionally, ceftezole sodium demonstrates alpha-glucosidase inhibition, contributing to its in vivo anti-diabetic effects. This compound is relevant for research in microbial resistance and diabetes therapeutic development. -
Bacterial Inhibitor
Sultamicillin tosylate is a broad-spectrum beta-lactamase inhibitor with potent antibacterial activity. This compound targets bacterial cell wall synthesis, making it effective against a variety of Gram-positive and Gram-negative bacteria. It is commonly used in microbiological research to study bacterial resistance mechanisms and to evaluate the efficacy of other antimicrobial agents. -
Bacterial Inhibitor
Sultamicillin is a broad-spectrum beta-lactam antibiotic that functions primarily by inhibiting bacterial cell wall synthesis. It exhibits significant antibacterial activity against a variety of gram-positive and gram-negative bacteria. This compound is utilized in research applications focused on investigating bacterial resistance mechanisms and evaluating the efficacy of antibiotic treatments. -
Bacterial Inhibitor
Clindamycin hydrochloride monohydrate is a bacterial inhibitor primarily targeting protein synthesis by binding to the 50S ribosomal subunit. This compound effectively suppresses the expression of virulence factors in Staphylococcus aureus, even at sub-inhibitory concentrations. Clindamycin hydrochloride monohydrate notably decreases the production of key toxins, including Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), and alpha-haemolysin (Hla), making it a valuable tool in microbiological research and the study of antibiotic resistance mechanisms. -
Bacterial Inhibitor
Cefoperazone sodium salt is a semisynthetic cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative bacteria. This compound is widely utilized in microbiological research and clinical applications to study bacterial resistance and the efficacy of antibacterial therapies. -
Bacterial Inhibitor
Cefotiam hexetil hydrochloride is a prodrug of cefotiam, functioning primarily as a bacterial inhibitor. While it is designed for oral administration, this third-generation cephalosporin itself does not exhibit antibacterial activity until metabolized to cefotiam in the body. It is used in research applications to study antibiotic effects and efficacy in targeting gram-negative and gram-positive bacterial infections. -
Bacterial Inhibitor
Ceftizoxime sodium is a third-generation cephalosporin antibiotic that functions as a bacterial inhibitor by binding to penicillin-binding proteins (PBPs). This action prevents bacterial cell wall synthesis, leading to cell lysis and death. It exhibits effectiveness against both Gram-negative and Gram-positive bacteria, making it valuable for research applications related to antibiotic resistance and bacterial infections. -
Bacterial Inhibitor
Saccharin sodium hydrate functions as a bacterial inhibitor, exhibiting bacteriostatic properties. This compound modulates the microbiome and serves as a non-caloric artificial sweetener. It is applicable in research exploring bacterial growth inhibition and the effects of sweeteners on microbial populations.
