Catalog No.
Product Name
Application
Product Information
Citations
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Anthraquinone Fungicide
Dithianon is a broad-spectrum anthraquinone fungicide that exhibits strong adhesion to the surfaces of leaves and fruits. It effectively controls various fungal pathogens, including anthracnose caused by Colletotrichum spp. and Elsinoe ampelina, as well as mildew due to Plasmopara viticola and phomopsis infections in Phomopsis viticola. This compound is widely utilized in agricultural research to enhance crop protection and improve yield by mitigating fungal disease incidence in fruits and vegetables. -
Antifungal Agent
Antifungal Agent 27 primarily targets fungal pathogens exhibiting antifungal activity. This compound demonstrates moderate antibacterial effects against Methicillin-Resistant Staphylococcus aureus (MRSA) and weak antifungal activity against Candida albicans SS5314, with minimal inhibitory concentration (MIC) values of 8 μg/mL and 32 μg/mL, respectively. It is suitable for research applications focusing on the development of novel antifungal therapies and the study of resistance mechanisms in pathogenic microbes. -
Antifungal Agent
2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin with notable antifungal properties, primarily targeting fungal pathogens. Isolated from the root tissue of Sanguisorba minor, this compound demonstrates strong inhibition of spore germination in Botrytis cinerea, making it valuable for research into antifungal mechanisms and plant defense responses. Its biological activity supports investigations into natural compounds for enhancing plant resistance to fungal infections. -
Antifungal And Antiviral
Verlamelin A is a macrocyclic depsipeptide known for its antifungal and antiviral properties. It exhibits significant antifungal activity against Aspergillus versicolor and Curvularia australiensis, alongside antiviral effects against HSV-1 with an IC50 of 16.7 μM. Isolated from the entomopathogenic fungus Lecanicillium sp., Verlamelin A serves as a valuable tool in antifungal and antiviral research applications. -
Fungal Inhibitor
Benzyl 2-hydroxy-6-methoxybenzoate acts as a potent fungal inhibitor, demonstrating significant antifungal activity with an IC50 of 25–26 μg/mL against various fungal strains. This compound is valuable in research focused on antifungal drug development and investigating fungal resistance mechanisms. Its efficacy makes it a promising candidate for further exploration in therapeutic applications against fungal infections. -
Antifungal Agent
Antifungal Agent 36 is a potent antifungal compound with a specific mechanism targeting Basidiomycetes. This reagent exhibits significant antifungal activity, making it suitable for research applications focused on fungal infections and related studies. It provides a valuable tool for investigating the efficacy of antifungal treatments in various biological systems. -
Antifungal Agent
Antifungal Agent 122 is a potent broad-spectrum antifungal compound, primarily targeting fungal phase transition and biofilm formation. This agent inhibits CYP3A4-M and CYP3A4-T enzyme activity with IC50 values of 2.11 µM and 4.53 µM, respectively. Notably, Antifungal Agent 122 demonstrates no cytotoxic effects, making it a valuable candidate for antifungal research applications. -
Antifungal Antibiotic
3'-O-Decarbamoylirumamycin is a 20-membered macrolide antibiotic that targets fungal infections, derived from Streptomyces subflavus subsp. Irumaensis. This compound exhibits significant antifungal activity against plant pathogenic fungi, including Piricularia oryzae and Sclerotinia cinerea. It is utilized in research focused on antifungal drug development and the study of fungal biology. -
Antifungal Agent
Plumieride is an antifungal agent that exhibits significant fungitoxicity against various dermatophytes. It demonstrates minimal cytotoxic activity, with an IC50 of 85 μg/mL against the P388 leukemia cell line. This compound is primarily utilized in studies focusing on antifungal efficacy and the evaluation of fungal pathogens. -
Antifungal Agent
Colutehydroquinone is an isoflavonoid primarily sourced from the root bark of Colutea arborescens. It demonstrates notable antifungal activity, making it a valuable reagent for research focused on fungal infections and related diseases. Its application in studying the mechanisms of antifungal action can contribute significantly to the development of new therapeutic strategies. -
Fungal Inhibitor
Antifungal agent 67 is an imidazole compound that targets fungal pathogens, demonstrating significant efficacy against Candida species. This agent exhibits a CC50 value of 33.6 μM in healthy neonatal rat cardiomyoblasts, indicating its potential impact on cellular viability. Antifungal agent 67 is suitable for research applications concerning antifungal mechanisms and the development of therapeutic strategies against fungal infections. -
1,3-β-glucan Synthase Inhibitor
Arborcandin C is a potent inhibitor of 1,3-β-glucan synthase, functioning as an antifungal antibiotic. It demonstrates strong biological activity with IC50 values of 0.15 μg/mL against Candida albicans and 0.015 μg/mL against Aspergillus fumigatus. Furthermore, Arborcandin C exhibits a minimum inhibitory concentration (MIC) of 1-2 μg/mL against various Candida species, making it valuable for research into antifungal mechanisms and treatments. -
Fungicidal Agent
Antifungal Agent 65 is a potent fungicidal agent targeting Fusarium oxysporum f.sp. cucumerinum. This compound demonstrates remarkable antifungal activity, making it suitable for various research applications in antifungal and antiviral studies. Its efficacy in combating specific fungal pathogens positions it as a valuable reagent for further exploration in agricultural and therapeutic research. -
Antifungal Agent
AEC5 is a lipopeptoid that exhibits antifungal activity specifically against Cryptococcus neoformans. It demonstrates a minimum inhibitory concentration (MIC) of 6.3 μg/mL without eliciting cytotoxic effects on human lung, liver, or red blood cells. This compound is suitable for research applications involving the study of antifungal mechanisms and the development of novel therapeutics targeting fungal infections. -
Anti-Fungal Agent
Enoxastrobin is an anti-fungal agent that targets various pathogenic fungi. It exhibits strong activity against Pyricularia oryzae and Botrytis cinerea, making it a valuable tool in agricultural research and crop protection studies. Its efficacy in inhibiting fungal growth supports investigations into disease management in agricultural systems. -
Antifungal Agent
SS-750 is an orally active triazole derivative that functions as an antifungal agent by binding to fungal cytochrome P450 enzymes. This compound exhibits potent antifungal activity against various Candida species, including C. parapsilosis, C. krusei, and C. glabrata, with MIC90 values of 0.25, 1, and 2 μg/mL, respectively. Additionally, SS-750 demonstrates efficacy in improving systemic and pulmonary infections caused by C. albicans. Its profile makes SS-750 a valuable reagent for research into antifungal therapies and resistance mechanisms. -
Antifungal Agent
Isopicropodophyllone is a natural compound derived from the leaves of Podophyllum hexandrum, functioning as a potent antifungal agent. It exhibits significant inhibitory effects on various fungal strains, making it valuable for research related to fungal infections and the development of antifungal therapies. Its effectiveness in disrupting fungal growth supports its potential applications in both medicinal chemistry and mycology studies. -
Fungicide
Pyrisoxazole is a fungicide that targets various fungal pathogens. It exhibits significant antifungal activity, making it suitable for agricultural applications to protect crops from fungal diseases. Research involving Pyrisoxazole contributes to the understanding of fungicidal mechanisms and can aid in the development of more effective plant protection strategies. -
Conidia Inhibitor
Carviolin is a conidia inhibitor derived from the mycelia of the ascomycete Neobulgaria pura. It effectively inhibits the formation of appressoria in germinating conidia of Magnaporthe grisea on hydrophobic surfaces. While exhibiting moderate cytotoxicity, Carviolin does not possess antifungal, antibacterial, or phytotoxic activities, making it a useful tool for studies focused on fungal germination and pathogenesis. -
Antifungal Agent
Tinophyllol is a furanoditerpenoid with demonstrated antifungal activity, particularly against Botrytis cinerea. Derived from the natural source Arcangelisia flava MERR, this compound is valuable for research applications in plant pathology and the study of fungal pathogens. Its efficacy in inhibiting fungal growth makes it a promising candidate for exploring new antifungal strategies. -
Antifungal Agent
Antifungal Agent 57 is a potent antifungal compound designed to inhibit Fluconazole-resistant strains of pathogens, particularly Candida albicans. With minimum inhibitory concentration (MIC) values ranging from 0.5 to 2 μg/mL, it demonstrates superior efficacy compared to conventional agents such as Miconazole. This compound serves as a valuable tool in the study of antifungal resistance and therapeutic development in mycology research. -
Antifungal Agent
Icofungipen is an orally active antifungal agent targeting Candida species through its unique structure as a beta amino acid. It exhibits significant toxicity against various strains of Candida, demonstrating protective effects on infected mice, notably enhancing survival rates during C. albicans infections. This compound is a valuable tool for research into antifungal mechanisms and the development of new therapeutic strategies against fungal infections. -
Fungal Inhibitor
Ophiobolin B is a sesterterpene metabolite derived from Helminthosporium oryzae, primarily functioning as a fungal inhibitor. This compound effectively inhibits proton extrusion in maize coleoptiles, while also blocking fusicoccin-promoted proton extrusion, potassium uptake, and subsequent cell enlargement. With minimal inhibitory concentration (MIC) values ranging from 25 to 50 μg/mL, Ophiobolin B demonstrates significant antifungal activity against various zygomycetes, making it valuable for research in plant-fungal interactions and cellular physiology. -
Antifungal Agent
Antifungal Agent 31 is a potent triazole antifungal agent that targets fungal cell membranes through inhibition of ergosterol biosynthesis. It exhibits significant antifungal activity against various Candida species and filamentous fungi. In preclinical studies using murine models, Antifungal Agent 31 demonstrated a marked reduction in mortality rates and kidney fungal burden, highlighting its potential in treating lethal systemic fungal infections. -
Volatile Organic Compound
Cis-3-Hexenyl benzoate is a volatile organic compound primarily utilized in fragrance and cosmetic applications due to its characteristic grassy aroma. This compound displays weak antifungal properties, making it suitable for various formulations. Additionally, cis-3-Hexenyl benzoate has an established safety profile, with negligible risks related to genotoxicity, reproductive toxicity, and environmental toxicity, while its skin sensitization potential is manageable within specified concentration limits. -
Secondary Metabolite
Neoaspergillic acid is a microbial secondary metabolite primarily isolated from the endophytic fungus Aspergillus sp. SPH2. It exhibits potent antifungal activity against several plant pathogens, including Alternaria alternata, Botrytis cinerea, and Fusarium oxysporum. Additionally, neoaspergillic acid demonstrates antitumor and antibacterial properties, making it a valuable compound for research in antifungal therapeutics and disease management in agricultural applications. Its presence during the exponential growth phase of fungi further highlights its significant biological role. -
Antifungal Agent
Antifungal agent 47 is a potent fungicide that acts by inhibiting adenosine 5'-triphosphate synthesis, resulting in robust respiratory inhibition across a variety of fungal strains. Its broad-spectrum fungicidal activity makes it suitable for research applications aimed at understanding fungal resistance mechanisms and developing new treatments for fungal infections. This compound is a valuable tool for exploring antifungal pharmacology and potential therapeutic interventions. -
Anti-fungal Agent
1,3,6-Trihydroxy-5-methoxyxanthone is a natural compound known for its anti-fungal properties. Isolated from the root bark of Tovomita krukovii, it exhibits significant inhibitory effects against various fungal pathogens. This compound is valuable for research applications focused on fungal infections and the development of new antifungal agents. -
Defensin-like Antifungal Peptide
Gymnin is a defensin-like antifungal peptide that exhibits notable antifungal activity against both phytopathogenic and mycotoxigenic fungi. Additionally, Gymnin inhibits HIV-1 reverse transcriptase with an IC50 of 200 μM and suppresses tumor cell proliferation, although it demonstrates only weak mitogenic activity in murine splenocytes. This compound is suitable for research applications related to plant disease treatment and the exploration of antifungal mechanisms. -
Fungal
(Rac)-Paclobutrazol-15N3 is a nitrogen-15 isotopically labeled derivative of Rac-Paclobutrazol, primarily targeting fungal organisms. This reagent is utilized in studying the metabolic pathways and ecological interactions of fungi, enabling researchers to trace compound distribution and assess its biological impacts in various environments. Its applications include research in plant-fungal interactions, agricultural science, and biochemistry related to fungal inhibition. -
Anti-fungal Agent
Guignardone K is a meroterpene compound derived from the endophytic fungus Guignardia sp. This compound exhibits potent antifungal activity, making it a valuable tool for research focused on fungal infections and the development of novel antifungal agents. Its mechanism of action contributes to an enhanced understanding of fungal biology and potential therapeutic strategies. -
Anti-fungal Triterpene Saponin
3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester is an anti-fungal triterpene saponin targeting fungal cell membranes. Derived from the aerial parts of Clematis tangutica, this compound demonstrates significant antifungal activity against various strains, including P. avellaneum, C. glabrata, S. cerevisiae, and T. beigelii, with the most pronounced effect noted against S. cerevisiae. Its bioactivity makes it a valuable reagent for studies investigating antifungal mechanisms and potential therapeutic applications. -
Antifungal Agent/C-4 Sterol Methyl Oxidase Inhibitor
PF-1163A is an antifungal agent that functions as a C-4 sterol methyl oxidase inhibitor, effectively disrupting ergosterol synthesis with an IC50 of 12 ng/mL. This compound demonstrates notable antifungal activity, characterized by a minimum inhibitory concentration (MIC) of 12.5 µg/mL. PF-1163A is valuable for research applications focused on fungal infections and the mechanistic understanding of ergosterol biosynthesis. -
Antifungal Agent
Antifungal Agent 125 is a potent inhibitor of succinate dehydrogenase (SDH), demonstrating an IC50 value of 3.59 μg/mL. This compound exhibits significant fungicidal activity against the fungal pathogen Alternaria alternata, making it a valuable tool for research in antifungal mechanisms and treatments. Its specific action on SDH positions it as a candidate for further exploration in the development of antifungal strategies. -
Chitin Deacetylase Inhibitor
AnCDA-IN-1 is a selective inhibitor of chitin deacetylase (CDA), demonstrating significant antifungal properties. It exhibits an IC50 value of 4.24 μM against AnCDA from Aspergillus nidulans and shows a minimum inhibitory concentration (MIC) of 260 μg/mL against various food spoilage and plant pathogenic fungi, with a minimum fungicidal concentration (MFC) of 520 μg/mL. This compound is valuable for research in the antifungal domain, particularly in understanding CDA's role in fungal cell wall integrity and potential therapeutic applications. -
Fungicide
Furmecyclox is a potent fungicide targeting basidiomycetes. It exhibits significant antifungal activity, making it suitable for both agricultural and laboratory applications in managing fungal diseases. Furmecyclox can be used to investigate the mechanisms of fungal growth inhibition and is essential for research focusing on mycology and plant pathogenesis. -
Fungal
3',5,5'-Trichlorosalicylanilide (TCSA) primarily inhibits fungal morphogenesis by disrupting key developmental processes. This compound effectively prevents biofilm formation and restricts the ability of fungi to invade host cells. TCSA is valuable in researching antifungal mechanisms and developing potential therapeutic strategies against fungal infections. -
Antimycotic Agent
Buclosamide is an antimycotic agent that exhibits potent antifungal activity by inhibiting the growth of various pathogenic fungi. It is primarily used in topical formulations to treat fungal infections of the skin and mucous membranes. Its efficacy in targeting fungal pathogens makes it a valuable tool in dermatological research and therapeutic applications. -
Antifungal Agent
SDZ89-485 is an orally active triazole antifungal agent that targets fungal cells, specifically disrupting ergosterol biosynthesis. In preclinical studies, SDZ89-485 demonstrated a superior antifungal effect against spore-forming fungi in mouse models, despite lower peak concentrations compared to traditional therapies. This compound is suitable for research applications focused on antifungal activity and mechanisms of resistance in fungal pathogens. -
Antifungal Agent
Antifungal agent 77 (Compound 13h) primarily targets fungal pathogens, exhibiting potent antifungal activity. At a concentration of 500 μg/mL, it demonstrates noteworthy insecticidal effects against various pests, including Mythimna separate, Helicoverpa armigera, Ostrinia nubilalis, and Spodoptera frugiperda, resulting in mortality rates of 30%, 25%, 40%, and 25%, respectively. Additionally, antifungal agent 77 exhibits toxicity in zebrafish embryos with a calculated LC50 of 2.43 μg/mL, highlighting its potential implications in ecological toxicology studies. -
Antifungal and Antiparasitic Agent
Oleylphosphocholine is an orally active antifungal and antiparasitic agent targeting invasive fungal infections and parasitic diseases. It demonstrates significant efficacy in the treatment of conditions such as aspergillosis and visceral leishmaniasis. This compound is valuable for research focused on developing therapeutic strategies against these challenging infectious diseases. -
Antifungal Agent
Antifungal Agent 25 is a potent broad-spectrum antifungal compound that targets various fungal pathogens. It exhibits significant antifungal activity against Candida albicans, including strains resistant to fluconazole. Additionally, this agent demonstrates stable metabolic properties in vivo, making it a valuable tool for researching antifungal mechanisms and potential therapeutic applications in fungal infections. -
Antifungal Agent
N-(2-hydroxy-2-phenylethyl)acetamide is an antifungal agent derived from the solid rice cultures of the endophytic fungus Diaporthe eucalyptorum KY-9. This compound demonstrates significant antifungal activity against Alternaria solani, making it a valuable tool in the study of fungal pathogens. Its properties aid in the exploration of antifungal mechanisms and potential therapeutic applications in combating fungal infections. -
Antifungal Agent
[6]-Gingerdiol is an antifungal agent primarily derived from Zingiber officinale. It demonstrates effective antifungal activity against M. gypseum, exhibiting a minimum lethal concentration (MLC) of 422 μg/mL. This compound holds potential for research applications focused on developing antifungal therapies and studying fungal resistance mechanisms. -
Sesquiterpenoid
1β-Acetoxypolygodial is a sesquiterpenoid derived from Tasmannia lanceolata, exhibiting significant biological activity against cancer cells and fungal pathogens. Its properties make it a valuable tool for investigating therapeutic strategies in oncology and mycology research. The compound can be utilized in studies exploring its mechanisms of action and potential as a lead compound for drug development. -
Antifungal Agent
Bitertanol is a potent antifungal agent that targets various fungal species through inhibition of fungal sterol synthesis. It has demonstrated activity against a broad spectrum of fungi and is utilized in research applications involving antifungal drug development. Additionally, Bitertanol acts as an inducer of CYP1A1, CYP2B, and CYP3A in vivo, while inhibiting CYP1A in vitro, highlighting its relevance in studying cytochrome P450 enzyme interactions. -
Antifungal Agent
LW3 is a potent antifungal agent that targets a variety of fungal pathogens. It exhibits significant antifungal activity with EC50 values of 0.54 mg/L against Botrytis cinerea, 0.09 mg/L against Rhizoctonia solani, 1.52 mg/L against Sclerotinia sclerotiorum, and 2.65 mg/L against Fusarium graminearum. This compound is valuable for research applications aimed at developing effective treatments for fungal infections in agriculture and plant pathology. -
Antifungal Agent
Savirin is an antifungal agent that demonstrates potent in vitro antibacterial and antibiofilm properties. This compound has been shown to prevent skin infections caused by Staphylococcus aureus in vivo. Additionally, Savirin displays increased efficacy when used in combination with antibiotics, making it a valuable tool for research in microbial resistance and skin infection treatment. -
Antifungal Agent
Decussatin is an α-Amylase inhibitor derived from the Tibetan medicinal plant Swertia mussotii. By inhibiting the enzymatic activity of α-Amylases, Decussatin effectively reduces the hydrolysis of complex carbohydrates, leading to decreased glucose absorption in the intestines and lower blood glucose levels. While it demonstrates limited antibacterial and antifungal properties, Decussatin is primarily utilized in the study of type 2 diabetes and its management. -
Hyphal Formation Inhibitor
2-Dodecanol is an effective hyphal formation inhibitor with targeted activity against Candida albicans. By inhibiting SIR2 expression, it disrupts the morphological transition essential for pathogenicity. This compound is valuable for researchers studying fungal biology and the mechanisms of infection, as well as for developing potential antifungal strategies.
