Fosmanogepix (tautomerism) is an orally active broad-spectrum anti-invasive fungal compound that targets the Gwt1 enzyme, essential for the proper localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi. By inhibiting Gwt1, Fosmanogepix disrupts the localization of cell wall mannoproteins, leading to impaired cell wall integrity, inhibited biofilm and germ tube formation, and reduced fungal growth. This compound is valuable for researching invasive fungal infections and evaluating potential therapeutic interventions.
Fosmanogepix (tautomerism) is an orally active broad-spectrum anti-invasive fungal compound that targets the Gwt1 enzyme, essential for the proper localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi. By inhibiting Gwt1, Fosmanogepix disrupts the localization of cell wall mannoproteins, leading to impaired cell wall integrity, inhibited biofilm and germ tube formation, and reduced fungal growth. This compound is valuable for researching invasive fungal infections and evaluating potential therapeutic interventions.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
