Catalog No.
Product Name
Application
Product Information
Citations
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Anti-Fungal Agent
Chandrananimycin B acts as an anti-fungal agent with specific activity against Mucor species. In addition, it demonstrates anti-tumor cell effects on various cancer cell lines, including HT29, MFXF 529L, and MCF-7. This compound is valuable for research applications focused on fungal infections and cancer therapeutics. -
Antifungal Agent
NC-1175 hydrochloride is an antifungal agent that targets cell membrane H+-ATPase, disrupting essential ion homeostasis in fungi. This compound demonstrates significant antifungal activity and is employed in research focused on fungal infections and potential therapeutic strategies. Its mechanism may provide insights into treatment options for various fungal diseases. -
Cer1 Inhibitor
Cs-2d is a selective inhibitor of ceramide synthase 1 (Cer1) with notable potency against C. neoformans. This compound demonstrates significant antifungal activity, effectively inhibiting growth while exhibiting minimal off-target effects on human ceramide synthase 1 (hCerS1). Cs-2d is a valuable tool for research focused on invasive fungal infections, facilitating the study of therapeutic strategies targeting ceramide metabolism. -
Fungal Inhibitor
Griseofulvic acid is a metabolite of the antifungal agent Griseofulvin, acting as a potent fungal inhibitor. It is known to induce protein aggregation and facilitate tubulin polymerization in cell-free assays, making it a valuable tool in the study of fungal biology and cell dynamics. This compound can be utilized in research applications focusing on the mechanisms of antifungal activity and cytoskeletal interactions. -
Antitumor Agent
PD 113270 is an antitumor agent that functions primarily through the inhibition of specific cellular pathways. This compound has demonstrated notable inhibitory effects on yeast, indicating its potential use in studying antifungal mechanisms and tumor cell proliferation. PD 113270 is of particular interest for research applications in cancer biology and pharmacology, aiding in the exploration of new therapeutic strategies. -
Antimicrobial Agent
Quadrilineatin is an antimicrobial agent that exhibits significant antifungal and antibacterial activity. It disrupts microbial cell function, making it effective against a broad spectrum of pathogens. This reagent is applicable in research focused on infectious diseases and the development of antimicrobial therapies. -
Antifungal Agent
Antifungal Agent 134 primarily targets fungal pathogens by disrupting cellular membranes and mitochondrial function, resulting in substantial reactive oxygen species (ROS) accumulation. It exhibits potent antifungal activity with EC50 values of 3.24 μg/mL against Botrytis cinerea and varying efficacy against other fungi, including Alternaria and Fusarium species. In addition to its antifungal properties, Antifungal Agent 134 also demonstrates significant herbicidal activity against common field weeds such as Amaranthus retroflexus and Abutilon theophrasti. This compound is suitable for research focused on crop disease management and weed control strategies. -
Antifungal Agent
Bullatenone is a volatile bioactive compound sourced from Lophomyrtus bullata, primarily functioning as an antifungal agent. It exhibits significant inhibitory effects against fungal pathogens, including Candida albicans and Cladosporium resinae. Due to its multifaceted biological activities, Bullatenone is valuable in researching inflammatory conditions and infectious diseases. -
PXR Agonist
Tolindate is a potent PXR agonist, exhibiting an EC50 value of 8.3 μM. This compound demonstrates significant antifungal activity, making it a valuable tool for research in pharmacology and toxicology. Its ability to modulate the pregnane X receptor (PXR) may provide insights into drug metabolism and interactions with xenobiotics. -
Insect toxin
3-GlcA-28-AraRhaxyl-medicagenate is an insect toxin classified within the saponin family. This compound demonstrates notable antifungal properties and has been shown to induce mortality in rice weevils at concentrations as low as 0.1 mg/mL. It serves as a valuable tool for research into insecticidal agents and pest management strategies. -
Anthraquinone Derivative
Neobulgarone E is an anthraquinone derivative isolated from Neobulgaria pura HA A07-97, an ascomycete fungus. This compound effectively inhibits the formation of appressoria in Magnaporthe grisea, making it a valuable tool for research on fungal development and pathogenesis. Notably, Neobulgarone E exhibits minimal cytotoxicity and lacks antifungal, antibacterial, or phytotoxic effects, highlighting its specificity in targeting fungal processes without adversely affecting other biological systems. -
Lactone
Feigrisolide B is a lactone derived from Streptomyces griseus, exhibiting notable antiviral properties against Coxsackie virus B3 and antifungal activity against Sporobolomyces ochreata. Additionally, it demonstrates moderate inhibitory effects on the enzyme 3α-hydroxysterol dehydrogenase, making it a valuable compound for research into lipid metabolism and infectious diseases. This compound is suitable for studies involving fungal resistance mechanisms and viral pathogenesis. -
Fungi Inhibitor
Acremine I is a potent fungi inhibitor derived from the endophytic fungus Acremonium byssoides. It has demonstrated effective inhibition of Plasmopara viticola, making it a valuable tool for research on plant diseases, particularly grape downy mildew. This compound is useful for studying the mechanisms of fungal resistance and developing strategies for disease management in agriculture. -
Anti-Fungal Agent
Chondramide D is an anti-fungal agent that specifically targets Candida species, including various yeast forms such as Henson yeast and lipids yeast. This compound demonstrates significant antifungal activity but does not exhibit antibacterial properties against Gram-positive or Gram-negative bacteria. Chondramide D is valuable for research applications focused on fungal infection treatment and understanding yeast-related pathologies. -
Fungicide
Imazalil sulfate is a potent fungicide that primarily targets fungal pathogens in agricultural settings. It exhibits strong activation of the mouse pregnane X receptor (mPXR) while showing minimal interaction with the mouse constitutive androstane receptor (mCAR), indicating its specific metabolic effects. Research indicates that Imazalil sulfate can induce developmental abnormalities, disrupt gut microbiota, and impair hepatic metabolism, making it significant for studies on environmental and toxicological impacts of fungicides. -
Anti-Fungal Agent
Crocacin C functions as an anti-fungal agent, exhibiting significant activity against both yeast and filamentous fungi. In studies, it has been shown to inhibit mouse fibroblast L929 cells, highlighting its potential cytotoxic effects. Additionally, Crocacin C disrupts the bc1 segment of electronic transmission in calf heart microsomes, resulting in a redshift of the 569 nm peak in the cytochrome B reduction spectrum. These properties make it a valuable reagent for research in fungal pathogenesis and cellular bioenergetics. -
Fungal Inhibitor
Mollugogenol A is a potent fungal inhibitor that disrupts cellular integrity in fungal cells. It induces lipid peroxidation, leading to damage to sperm membranes, demonstrating significant sperm-killing activity. This compound is valuable for research applications focused on antifungal mechanisms and reproductive toxicity studies. -
Bc1 Complex Inhibitor
bc1 Complex-IN-1 is a potent inhibitor of the bc1 complex, demonstrating significant antifungal activity. This compound effectively exhibits fungicidal properties against Cucumber downy mildew (CDM), making it a valuable tool for studying fungal pathogenesis and potential therapeutic interventions. Its application in research can aid in understanding the mechanisms underlying fungal resistance and the development of effective fungicides. -
Antifungal Agent
Vermistatin is an antifungal agent derived from the fungal strain Guignardia. It exhibits potent cytotoxic and antifungal activities, making it a valuable tool for studying fungal infections and testing antifungal efficacy. This reagent is useful in various research applications, including drug development and the investigation of fungal pathogenesis. -
Anti-Fungal Agent
Cyclothiazomycin is an antifungal agent that selectively inhibits renin activity while sparing other proteases such as pepsin, aspartic acid, serine, mercaptan protease, and metalloproteinases. Although it demonstrates weak antifungal activity, it serves as a valuable tool in research settings focused on elucidating renin-related pathways and their implications in fungal infections. Its specific inhibition profile makes it a candidate for studies exploring renin's role in various biological processes. -
Fungal CYP51A1 Inh
Becliconazole functions as an inhibitor of the fungal cytochrome P450 51A1 (CYP51A1) enzyme. This compound exhibits significant antifungal activity and is primarily utilized in research related to fungal infections, offering insights into the mechanisms of action and potential therapeutic interventions against fungal pathogens. -
Antifungal Agents
Pradimicin L is an antifungal agent derived from the Streptomyces madurensis species. This homolog of pradimicin A exhibits potent antifungal activity, making it a valuable tool for research in mycology and fungal infection studies. Its efficacy in disrupting fungal cell integrity highlights its potential for further investigation in the development of antifungal therapies. -
Anti-Fungal Agent
Haliangicin C is an anti-fungal agent targeting filamentous fungi and oomycetes. It exhibits potent activity against a range of filamentous fungal pathogens, making it a valuable tool for studying fungal infections and their mechanisms. However, it does not demonstrate antibacterial activity, highlighting its specificity for fungal applications in research and therapeutic investigations. -
Anti-Fungal Agent
Ramulosin is an antifungal agent that effectively inhibits the germination of fungal meristems. Its primary mechanism involves disrupting fungal growth, making it a valuable tool for research in mycology and antifungal drug discovery. Ramulosin's activity can aid in understanding fungal pathogenesis and developing targeted therapies against fungal infections. -
Macrocyclic dilactone
De-N-methylpamamycin-593A is a macrocyclic dilactone that effectively induces aerial mycelium formation in fungi. This compound serves as a valuable tool in the study of fungal biology, particularly in understanding the mechanisms behind mycelial growth and development. Its unique structure and bioactivity make it pertinent for research in mycology and related fields. -
Chitin Synthase Inhibitor
Asulam potassium is a potent chitin synthase inhibitor that targets the biosynthesis of chitin in fungal cell walls. By disrupting the structural integrity of fungal cells, Asulam potassium effectively impedes normal growth and reproduction, demonstrating significant antifungal activity. This compound is valuable for research applications focused on managing fungal diseases, including downy mildew and gray mold, particularly in crops such as spinach, tulips, daffodils, and lilies. -
Fungicide
PPm is a potent succinate dehydrogenase inhibitor with demonstrated fungicidal activity. It effectively targets fungal respiratory pathways, disrupting energy production and leading to cell death. This compound is widely utilized in agricultural research and studies aimed at understanding fungal resistance mechanisms and developing novel fungicidal strategies. -
Antifungal Agent
SPK-843 is a potent antifungal agent that demonstrates significant inhibitory activity against Aspergillus fumigatus (MIC 0.5 μg/mL), Aspergillus flavus (MIC 0.25 μg/mL), and Aspergillus niger (MIC 0.0625 μg/mL). This compound exhibits dose-dependent efficacy in murine models of pulmonary aspergillosis, making it valuable for studying therapeutic strategies for fungal infections. SPK-843 can be employed in various research applications related to antifungal drug development and fungal pathogenesis. -
Anti-Fungal Agent
1,6-Dihydroxy-2-chlorophenazine is a compound that exhibits weak anti-fungal and anti-yeast activity. Its mechanism involves interference with cellular processes in fungi, making it a candidate for research in antifungal drug development. This compound may be utilized in studies investigating the mechanisms of fungal infection and resistance, as well as in screening assays for new therapeutic agents. -
Antifungal Agent
O-Acetylbenzeneamidinocarboxylic acid serves as an antifungal agent targeting various plant pathogenic fungi. This compound exhibits notable inhibitory activity, making it suited for research applications focused on understanding fungal infections and developing antifungal strategies in agricultural settings. Its effectiveness as a fungal metabolite positions it as a valuable tool in the study of plant pathology. -
Antifungal Agent
Eulicin is an antifungal agent primarily targeting fungal pathogens. It exhibits significant activity against both Gram-positive and Gram-negative bacteria and has demonstrated the ability to inhibit human immunodeficiency virus (HIV) infection and replication. Eulicin is derived from the genus Streptomyces, making it a valuable compound for research in microbial resistance and antiviral therapeutics. -
Antifungal Activity
4-Methyl-6,7-methylenedioxycoumarin is a coumarin derivative that displays significant antifungal activity. It demonstrates effectiveness against Pythium species, making it a valuable tool for research in antifungal applications. This compound is suitable for studies aiming to explore the mechanisms of antifungal resistance and the development of new antifungal agents. -
Diffusion Signaling Factor
Cis-11-Methyl-2-dodecenoic acid is a diffusion signaling factor (DSF) involved in quorum sensing (QS) within microbial and fungal communication systems. This compound plays a crucial role in regulating virulence and biofilm formation in several bacterial pathogens, making it a valuable tool for research on microbial interactions and pathogenesis. Its application extends to studies aimed at understanding the mechanisms of bacterial communication and the development of strategies to combat bacterial infections. -
Anti-Fungal Agent
Neosordarin is an effective antifungal agent that targets fungal pathogens, including Saccharomyces cerevisiae. It demonstrates potent inhibitory activity with an IC50 value ranging from 0.2 to 0.3 μg/mL. This compound is particularly valuable in research applications focused on understanding fungal resistance and developing antifungal therapies. -
Antifungal Antibiotic
PF-1163B is a potent antifungal antibiotic that targets fungal cell wall synthesis. It exhibits strong inhibitory activity against a range of pathogenic fungi, making it valuable for research into antifungal therapies and mechanisms of resistance. This compound can be utilized in studies aimed at understanding fungal pathogenesis and developing novel treatments for fungal infections. -
Antifungal Agent
Antifungal Agent 113 (compound 9a) is a potent compound targeting fungal and bacterial pathogens. It exhibits significant antifungal and antibacterial activity, specifically against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research applications focused on combating resistant infections and exploring antifungal mechanisms. -
Antifungal Agent
Ascochitine is a polyketide-derived secondary metabolite that serves as a selective antifungal agent. It demonstrates broad-spectrum phytotoxicity and antimicrobial properties, making it a valuable tool in agricultural and chemical research applications focused on combating fungal pathogens. This compound can be utilized for studies investigating plant-fungal interactions and the development of antifungal strategies. -
Fungal Inhibitor
Kayahope is a potent fungal inhibitor that targets key enzymes involved in fungal cell wall biosynthesis. This compound demonstrates significant antifungal activity against various fungal pathogens, making it a valuable tool in the study of fungal infections and their treatment. Kayahope's utility extends to research applications in microbiology and pharmacology, aiding in the development of new antifungal therapies. -
Anti-Fungal Agent
Haliangicin A is an anti-fungal agent targeting filamentous fungi and oomycetes. It demonstrates significant activity against a range of fungal pathogens, making it a valuable tool for studying fungal biology and developing antifungal strategies. Notably, Haliangicin A exhibits no antibacterial activity, which underscores its specificity in targeting fungal organisms. This compound is suitable for research applications focused on mycology and antifungal pharmacology. -
Staphylococcus aureus Inhibitor, Candida albicans Inhibitor
5,6,7,8-Tetramethoxyflavone is a flavonoid that acts as an inhibitor of *Staphylococcus aureus* and *Candida albicans*. This compound exhibits significant antibacterial and antifungal activities, making it valuable for research focused on microbial infections. Its ability to impede the growth of these pathogens supports its use in studies investigating therapeutic strategies against bacterial and fungal infections. -
Antifungal Agent
(E)-Isoeugenol acetate is a derivative of Eugenol known for its antifungal properties. This compound has demonstrated efficacy against various fungal strains, making it a valuable tool in mycology research and antifungal studies. Its applications include investigating mechanisms of action against fungal pathogens and exploring potential therapeutic uses in antimicrobial formulations. -
Anti-Fungal Agent
Phosmidosine is an anti-fungal agent that primarily targets the cell cycle mechanisms in eukaryotic cells. It has been shown to inhibit cell cycle progression and prevent morphological recovery in srcts-NRK cells, demonstrating its potential efficacy in fungal pathogenesis research. This compound is valuable for studying antifungal properties and elucidating the underlying biological processes in fungal cell growth and division. -
Fungal Inhibitor
Dactylfungin A is an α-pyrone-containing compound that functions as a potent antifungal agent, primarily targeting fungal cell processes. Isolated from Dactylaria parvispora, it exhibits significant inhibitory activity against various fungal strains. This compound is valuable for research applications focused on understanding fungal biology and developing antifungal therapies. -
Anti-Fungal Agent
Chivosazol A is an antifungal agent exhibiting potent activity against yeast and filamentous fungi. This compound demonstrates significant toxicity towards mammalian cells, making it a valuable tool for researchers investigating fungal infections and cellular responses to antifungal agents. Its efficacy in targeting diverse fungal species positions Chivosazol A for applications in pharmaceutical studies and the development of novel antifungal therapies. -
Anti-Fungal Agent
Enactin Ib is an anti-fungal agent derived from the strain of Streptomyces roseoviridis. It exhibits limited antifungal activity and can be used for research focused on the mechanisms of fungal resistance and the development of new antifungal therapies. Its unique structural properties may provide insights into the modification of antifungal compounds for enhanced efficacy. -
Anti-Invasive Fungal Infection Compound
Fosmanogepix (tautomerism) is an orally active broad-spectrum anti-invasive fungal compound that targets the Gwt1 enzyme, essential for the proper localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi. By inhibiting Gwt1, Fosmanogepix disrupts the localization of cell wall mannoproteins, leading to impaired cell wall integrity, inhibited biofilm and germ tube formation, and reduced fungal growth. This compound is valuable for researching invasive fungal infections and evaluating potential therapeutic interventions. -
Antimicrobial Agent
Epelmycin D is a potent antimicrobial agent with activity against both Gram-positive and Gram-negative bacteria, as well as Candida albicans. In addition to its antifungal and antibacterial properties, Epelmycin D demonstrates significant antileukemic activity against the L1210 cell line, surpassing the efficacy of Aclacinomycin. This compound is valuable for research applications focused on infectious disease and cancer therapeutics. -
Antifungal
(+)-β-Pinene is a natural enantiomer with demonstrated antifungal properties. Its primary mechanism involves disrupting the integrity of fungal cell walls, leading to compromised cellular function and viability. This compound is utilized in various biological research applications, particularly in studies focused on fungal pathogenesis and the development of antifungal agents. -
Pesticide/Fungicide
Triticonazole is a triazole fungicide that inhibits the biosynthesis of ergosterol by targeting the cytochrome P450 enzyme system in fungi. This compound exhibits broad-spectrum antifungal activity, making it effective in controlling various fungal pathogens in agricultural applications. Additionally, Triticonazole has been studied for its potential endocrine-disrupting effects, contributing to research in environmental toxicology and pesticide safety. -
CYP51 Inhibitor
Pipercroside A is a potent CYP51 inhibitor derived from Piper crocatum Ruiz & Pav. This compound exhibits significant antifungal activity, making it a valuable tool in studies of fungal infections and drug resistance mechanisms. Its role in inhibiting sterol biosynthesis positions Pipercroside A as a candidate for further investigation in antifungal therapeutic development.
