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SDH-IN-44

Catalog No.: A27490
SDH Inhibitor
SDH-IN-44 is a succinate dehydrogenase (SDH) inhibitor that demonstrates an IC50 of 12.5 μg/mL against Alternaria solani. This compound exhibits significant antifungal activity by inhibiting fungal mycelial growth, making it a valuable tool in the study of fungal infections. Research applications include understanding mechanisms of fungal pathogenicity and exploring therapeutic strategies for fungal diseases.
SDH-IN-44 3103433-67-3 SDH Inhibitor
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSDH-IN-44 is a succinate dehydrogenase (SDH) inhibitor that demonstrates an IC50 of 12.5 μg/mL against Alternaria solani. This compound exhibits significant antifungal activity by inhibiting fungal mycelial growth, making it a valuable tool in the study of fungal infections. Research applications include understanding mechanisms of fungal pathogenicity and exploring therapeutic strategies for fungal diseases.
Product Information
Catalog NumA27490
FormulaC17H16F5N3O2
Molecular Weight389.32
CAS Number3103433-67-3
SMILESFC1=C(F)C=C(/C=C/C(C)N(OC)C(C2=CN(C)N=C2C(F)F)=O)C=C1F
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Microbiology > Antifection > Fungal