Columbamine chloride is a quaternary isoquinoline alkaloid known for its biological activity as a cytochrome P450 (CYP) isoform CYP3A4 inhibitor, with an IC50 of 30.6 µM. This compound induces apoptosis in cancer cells and exhibits a range of biological effects, including antioxidant, anti-inflammatory, antitumor, antifungal, antiparasitic, hepatoprotective, neuroprotective, hypolipidemic, and hypoglycemic properties. Columbamine chloride is suitable for various research applications focusing on cancer biology, metabolic disorders, and neuroprotection.
Columbamine chloride is a quaternary isoquinoline alkaloid known for its biological activity as a cytochrome P450 (CYP) isoform CYP3A4 inhibitor, with an IC50 of 30.6 µM. This compound induces apoptosis in cancer cells and exhibits a range of biological effects, including antioxidant, anti-inflammatory, antitumor, antifungal, antiparasitic, hepatoprotective, neuroprotective, hypolipidemic, and hypoglycemic properties. Columbamine chloride is suitable for various research applications focusing on cancer biology, metabolic disorders, and neuroprotection.
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