Catalog No.
Product Name
Application
Product Information
Citations
- Retinyl glucoside is a naturally occurring and biologically active metabolites of vitamin A, which are found in fish and mammals.
- sodium 4-pentynoate is a alkynylacetate analogue; can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types.
- Sodium formononetin-3'-sulfonate is a water-sol. derivate of formononetin.
-
MyD88 dimerization Inhibitor
ST 2825 is a MyD88 pharmacologic inhibitor.- Bernard Kan, .et al. , Nat Commun, 2018, 9: 4822 PMID: 30446641
- Shira Dishon, .et al. , Sci Rep, 2018, 8: 9476 PMID: 29930295
-
Morphine-like substance
Beta-lipotropin (beta-LPH) was found to contain within its C-terminal sequence the primary structure of these peptides. -
TPA/PMA inhibitor
Cyclosporin H is a TPA/PMA inhibitor and a selective inhibitor of formyl peptide receptors (Ki = 0.1 uM).- Jean-Philippe Auger, .et al. , Nature, 2024, May;629(8010):184-192 PMID: 38600378
-
Cell adhesion inhibitor
K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1beta or TNF-alpha. -
DNA repair inhibitor
KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin?€?s lymphoma. -
mitochondria-targeted antioxidant
SKQ1 is a potent mitochondria-targeted antioxidant. SKQ1 is also an API (active pharmaceutical ingredient) for making eye drop drug called Visomitin. SKQ1 showed activities (1) to prevent amyloid-beta-induced impairment of long-term potentiation in rat hippocampal slices.- Massimo Costanza, .et al. , PNAS, 2019, 2019 PMID: 30988194
- Ursodeoxycholic acid (UDCS) is a cell protectant used extensively to mitigate hepatic and biliary diseases.
- CPI-268456 is a ligand of bromodomain-containing protein 4 (BRD4). It binds to BRD4 (IC50 = <0.5 μM in a cell-free assay) and inhibits LPS-induced IL-6 secretion in THP-1 cells (IC50 = <0.5 μM).
-
luminescent enzyme substrate
Coelenterazine is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques. - Brevianamide F belongs to a class of naturally occurring 2,5-diketopiperazines.
- Alanosine is an amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
- GABOB is an anticonvulsant which is used for the treatment of epilepsy in Europe, Japan, and Mexico.
- Isosorbide Mononitrate is a drug used principally in the treatment of angina pectoris and acts by dilating the blood vessels so as to reduce the blood pressure.
- Fluoxymesterone is an anabolic steroid with strong androgenic properties that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
- Hexaminolevulinate HCl is the hexyl ester of 5-aminolevulinic acid (ALA) with photodynamic properties.
-
polyamine synthesis inhibitor
Sardomozide is a second-generation polyamine synthesis inhibitor, which inhibits the activity of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (SAMDC). - Sugammadex soidum is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia.
-
PPCE inhibitor
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor. - 4-Aminobenzoic acid is an intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi.
- 4-Aminoantipyrine is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties.
- i-Inositol is a chemical compound which is sugar alcohol. i-Inositol is involved in a number of biological processes including insulin signal transduction, cytoskeleton transduction and so on.
- Citric acid trilithium salt tetrahydrate is a pharmaceutical and construction material.
