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Biological Activity
Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA). It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 ?M).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 30.19 mL | 150.93 mL | 301.85 mL |
0.5 mM | 6.04 mL | 30.19 mL | 60.37 mL |
1 mM | 3.02 mL | 15.09 mL | 30.19 mL |
5 mM | 0.6 mL | 3.02 mL | 6.04 mL |
*The above data is based on the productmolecular weight 331.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A17897 |
---|---|
CAS No. | 135-09-1 |
Formula | C8H8F3N3O4S2 |
M. Wt | 331.29 |
Purity | >98% |
Synonyms | Hydroflumethiazide; Diuredemina; Glomerulin; Hidroflumetiazid; Diurometon; Flutizide; |
SMILES | C1NC2=C(C=C(C(=C2)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N1 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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