Hydroflumethiazide

Catalog No.: A17897

Hydroflumethiazide

Hydroflumethiazide Chemical Structure

CAS NO. 135-09-1

Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA). It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 ?M).

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Biological Activity

Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA). It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 ?M).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.19 mL 150.93 mL 301.85 mL
0.5 mM 6.04 mL 30.19 mL 60.37 mL
1 mM 3.02 mL 15.09 mL 30.19 mL
5 mM 0.6 mL 3.02 mL 6.04 mL

*The above data is based on the productmolecular weight 331.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17897
CAS No. 135-09-1
Formula C8H8F3N3O4S2
M. Wt 331.29
Purity >98%
Synonyms Hydroflumethiazide; Diuredemina; Glomerulin; Hidroflumetiazid; Diurometon; Flutizide;
SMILES C1NC2=C(C=C(C(=C2)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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