Catalog No.
Product Name
Application
Product Information
Citations
- Thymosin β4 is naturally occuring, potent regulator of actin polymerization present in human platelets at a concentration of 200 - 500 uM.
- CM 346 is an anxiolytic drug, produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.
- Picoplatin is a new generation organic platinum analog with an extended spectrum of antineoplastic activity.
- Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade.
- FPH2 (BRD-9424) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.
- Enhances differentiation of induced pluripotent stem cells (iPSCs) to hepatocytes; also promotes the maturation of iPSC-derived hepatocytes.
-
OSC Inhibitor
Ro 48-8071 is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity. - Abscisic Acid is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism.
- Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.
-
NQO1 inhibitor
Dicoumarol is a competitive NADH quinone oxidoreductase (NQO1) inhibitor. -
cholinephosphotransferase inhibitor
Meclofenoxate HCl is an anti-aging drug used to treat the symptoms of senile dementia and Alzheimer's disease, and also inhibits the activity of cholinephosphotransferase. - FPH1 is a small molecule, which promotes expansion of iPS-derived hepatocytes.
- Ro 48-8071 inhibits cholesterol biosynthesis at the level of 2,3-oxidosqualene cyclase (OSC). It blocks OSC and cholesterol synthesis in HepG2 cells in the nanomolar range. A novel lipid lowering agent.
-
c-Fos inhibitor
T-5224 is a selective inhibitor of c-Fos/activator protein-1.- Kamata Y, .et al. , J Dermatol Sci, 2018, Apr 23. pii: S0923-1811(18)30186-5 PMID: 29730173
- Benzyl alcohol is an aromatic alcohol; a colorless liquid with a mild pleasant aromatic odor.
- Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
- LH-RH, human is a biochem/physiol Actions LHRH Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.
- Anisole methoxybenzene is a colorless liquid with a smell reminiscent of anise seed, and in fact many of its derivatives are found in natural and artificial fragrances.
- Triisopropylsilane is a highly selective reducing agent which can be used to prepare anti-1,2-diols.
- Bisoctrizole is a broad-spectrum ultraviolet radiation absorber, absorbing UVB as well as UVA rays. Also a hybrid UV absorber, reflecting and scattering UV.
- (Z)-2-decenoic acid is an unsaturated short chain fatty acid that is secreted by P. aeruginosa and induces a disp .
- 9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations.
- Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1), an antioxidant dietary supplement.
- Deferasirox Fe3+ chelate is a rationally-designed oral iron chelator; its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias.
-
DA neurotoxin
MPTP hydrochloride induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats.- Sai Teja Meka, .et al. , Eur J Pharmacol, 2023, Nov 15:959:176067 PMID: 37751833
- Philemon Dauda Shallie, .et al. , Annual Research & Review in Biology, 2017, 13(5): 1-11
-
SE inhibitor
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. -
SE inhibitor
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway.- Gia-Buu Tran, .et al. , Cancer Res, 2023, Apr 14;CAN-22-3450 PMID: 37057874
- Weber RA, .et al. , Mol Cell, 2020, Feb 6;77(3):645-655 PMID: 31983508
- Garcia-Bermudez J, .et al. , Nature, 2019, Feb 13 PMID: 30760928
- Pafuramidine is an orally bioavailable prodrug of furamidine, which has clinical activity against Pneumocystis pneumonia.
