Others

Bendroflumethiazide is a thiazide diuretic used to treat hypertension. Bendroflumethiazide works by inhibiting sodium reabsorption at the beginning of the distal convoluted tubule and may play an important role in the treatment of mild heart failure.

alpha-Tocopherol is one of the most abundant isoforms of vitamin E. alpha-Tocopherol is a biologically active liposoluble vitamin and potent antioxidant.

Laurocapram is a chemical enhancer for skin permeation of drug.

Propacetamol Hydrochloride is a prodrug of paracetamol (PCM), being effectively used to treat fever and pain.

Xanthinol niacinate is a combination of xanthinol and niacin which acts as a vasodilator.

Menbutone is an oxobutyric acid derivative and acts as a choleretic.

Nikethamide is a central nervous system stimulant. It is a clear light yellow viscous liquid or crystalline solid and has a slightly bitter taste followed by a faint sensation of the warmth.

Actarit is a drug that has been shown to suppress disease activity of rheumatoid arthritis (RA). Actarit reduces spontaneous tumor necrosis factor-alpha and interleukin 1beta secretion by primary synovial cells of patients with RA.

Clonixin, also known as lysine clonixinate and Deltar, is a non-steroidal anti-inflammatory used in the treatment of migraines.

Xipamide is a sulfamoylbenzamide analog of Clopamide. It is a diuretic as well as a saluretic with antihypertensive activity. It is bound to plasma proteins, thus has a delayed onset and prolonged action.

Sulbutiamine is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.

Iodixanol is a contrast agent. It is commonly used as a contrast agent during coronary angiography. It is the only iso-osmolar contrast agent, with an osmolality of 290 mOsm/kg H2O??the same as blood.

Ufenamate is a topical analgesic.

Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.

Bromisoval, also known as bromovalerylurea, is a bromide-containing sedative-hypnotic that is occasionally combined with non-steroidal anti-inflammatory drugs in over-the-counter products.

Diflorasone is used in topical corticosteroids for its anti-inflammatory effect.

Desoximetasone is a medication belonging to the family of medications known as topical corticosteroids. It is used for the relief of various skin conditions, including rashes. It helps to reduce redness, itching, and irritation.

Acetohexamide is a sulfonylurea derivative. Acetohexamide is a hyopglycemic agent with moderate uricosuric activity. Acetohexamide is a first generation medication used in the treatment of diabetes metilus type 2.

Phthalic acid is an aromatic dicarboxylic acid,. It is an isomer of isophthalic acid and terephthalic acid.

Sodium lauryl sulfate is an anionic surfactant, usually a mixture of sodium alkyl sulfates, mainly the lauryl; lowers surface tension of aqueous solutions; used as fat emulsifier, wetting agent, detergent in cosmetics, pharmaceuticals and toothpastes; also as research tool in protein biochemistry.

Triethyl citrate is an ester of citric acid. It is a colorless, odorless liquid used as a food additive to stabilize foams, especially as whipping aid for egg white. It is also used in pharmaceutical coatings and plastics.

Scopolamine is an alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in URINARY INCONTINENCE, in MOTION SICKNESS, as an antispasmodic, and as a mydriatic and cycloplegic.

Phensuximide is an anticonvulsant in the succinimide class. It suppresses the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in petit mal seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex.

Ethotoin is an anticonvulsant drug used in the treatment of epilepsy. It is a hydantoin, similar to phenytoin. Ethotoin lacks phenytoin's side effects of gingival hyperplasia and hirsutism; however, it is less effective. This, combined with the need for frequent dosing has limited its usefulness. Ethotoin is no longer widely used.

Haloperidol decanoate is a typical antipsychotic drug used as maintenance therapy for schizophrenia and mood disorders formulated as an ester for intramuscular injection.

Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA). It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 ?M).

Timonacic is a cyclic sulfur amino acid derivative with potential antineoplastic and antioxidant activities.

Bismuth subcitrate contains tripotassium di-citratobismuthate used in gastric & duodenal ulcer therapy. Bismuth subcitrate potassium is a bismuth salt used in combination with antibiotics and a proton pump inhibitor for the treatment of Helicobacter pylori infections.

Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders.

Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM.

Tolazamide is an oral blood glucose lowering drug used for people with Type 2 diabetes. It is part of the sulfonylurea family (ATC A10BB).

Oxalamine Citrate is a cough suppressant.

Benfluorex hydrochloride (JP-992 hydrochloride) is a hepatic nuclear factor 4 alpha (HNF4α) activator.

Ethamivan, or etamivan, is a respiratory stimulant drug related to nikethamide. It has been mainly used in the treatment of barbiturate overdose and chronic obstructive pulmonary disease.

Heptaminol hydrochloride is an amino alcohol used as a myocardial stimulant, vasodilator, and to relieve bronchospasm. Its most common therapeutic use is in orthostatic hypotension.

Sulfacarbamide is an antimicrobial agent that has been investigated as a therapeutic biochemical for diabetes treatment. It may lower blood sugar.

Quinidine is a dextrorotatory stereoisomer of quinine with antimalarial and antiarrhythmic properties.

Fursultiamine is a compound used for therapy of thiamine deficiency. It??s phosphorylated metabolites may be administered as multivitamin preparations. Fursultiamine has been identified as a drug candidate against prostate cancer from the aspect of somatic cell reprogramming and may be useful as a therapeutic tool in number of human neurological diseases.

Apronalide, also known as Allylisopropylacetylurea or Apronal, is a hypnotic/sedative drug of the ureide (acylurea) group which may induce cytochrome P-450 through barbiturate-like activity.

Triamcinolone hexacetonide is an anti-inflammatory.

Cholestyramine (Colestyramine) is a bile acid binding resin and can inhibit intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol.

Calcium polystyrene sulfonate is an ion-exchange resin used for reducing blood levels of potassium. Calcium polystyrene sulfonate is used to treat hyperkalemia in patients with chronic kidney disease (CKD).

Talaporfin (ME2906; NPe6) is a photosensitizer used in photodynamic therapy (PDT).

PF-3187207 is a a nitric oxide (NO)-donating latanoprost with prostaglandin activity. It loweres intraocular pressure (IOP) more effectively than latanoprost in monkeys, dogs and rabbits.

Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS).

Flurandrenolide is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Flurandrenolide exerts its effects by interacting with specific cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression.

Vinburnine, also known as Eburnamonine, is a vasodilator. Vinburnine is a vinca alkaloid and a metabolite of vincamine.

Dodecyl alcohol, ethoxylated is a bioactive chemical.

Famprofazone, also known as Geodowin, is an analgesic used for fever and pain relief. Famprofazone has been demonstrated to be metabolized to methamphetamine and amphetamine following administration. Data shows the famprofazone metabolites amphetamine and methamphetamine to be both d- and l-enantiomers.

Lofendazam is a benzodiazepine derivative that has sedative and anxiolytic effects.