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  1. Alanosine is an amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
  2. GABOB is an anticonvulsant which is used for the treatment of epilepsy in Europe, Japan, and Mexico.
  3. Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood can't flow to the tissues.
  4. Isosorbide Mononitrate is a drug used principally in the treatment of angina pectoris and acts by dilating the blood vessels so as to reduce the blood pressure.
  5. neuroprotective and neurotrophic compound

    J147 is a potent neuroprotective and neurotrophic compound. J147 protects against neurotoxicity in cortical neurons in vitro (EC50 = 25 - 200 nM).
  6. Emeramide is a mercury and heavy metal chelator.
  7. Fluoxymesterone is an anabolic steroid with strong androgenic properties that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
  8. Hexaminolevulinate HCl is the hexyl ester of 5-aminolevulinic acid (ALA) with photodynamic properties.
  9. polyamine synthesis inhibitor

    Sardomozide is a second-generation polyamine synthesis inhibitor, which inhibits the activity of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (SAMDC).
  10. Sugammadex soidum is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia.
  11. ABHD6 inhibitor

    WWL70 is a potent inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50 = 70 nM), an enzyme which catalyzes the hydrolysis of 2-arachidonylglycerol.
  12. PPCE inhibitor

    Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor.
  13. 4-Aminobenzoic acid is an intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi.
  14. 4-Aminoantipyrine is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties.
  15. Iopamidol is a non-ionic, water-soluble radiographic contrast agent.
  16. i-Inositol is a chemical compound which is sugar alcohol. i-Inositol is involved in a number of biological processes including insulin signal transduction, cytoskeleton transduction and so on.
  17. Citric acid trilithium salt tetrahydrate is a pharmaceutical and construction material.
  18. Selective chymase substrate

    RETF-4NA is a chymase substrate peptide that is cleaved more avidly by α2-macroglobulin-bound chymase than the free, unbound form.
  19. Prolyl endopeptidase inhibitor

    Y-29794 oxalate, inhibitor of prolyl endopeptidase, is a serine peptidase that may be implicated in the biosynthesis of amyloid β-peptide.
  20. Proprotein convertases inhibitor

    Decanoyl-RVKR-CMK is a selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases.
  21. ECE inhibitor

    CGS 35066 is a a potent endothelin-converting enzyme (ECE) inhibitor.
  22. furin inhibitor

    Hexa-D-arginine is a inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 uM for furin, PACE4 and PC1 respectively).
  23. Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.
  24. SSAO/VAP-1 inhibitor

    PXS-4728A is a very potent and highly selective compound in development for the treatment of cardiometabolic diseases like the liver-related disease Nonalcoholic Steatohepatitis (NASH).
  25. Complex III modulator

    S3QEL 2 is a selective inhibitor of superoxide production from the outer Q-binding site of mitochondrial respiratory complex site III (IIIQo) without altering oxidative phosphorylation.
  26. TACC3 inhibitor

    SPL-B, Orally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells.
  27. Butamben is a long-duration local anesthetic used for the treatment of chronic pain.
  28. LSC inhibitor

    BRD 7116 is a potent and selective Inhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM).
  29. The single isomer, 6-Carboxyfluorescein, contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid.
  30. Povidone iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine.
  31. HA15 is a molecule that targets specifically BiP/GRP78/HSPA5.
  32. Hydroquinidine is an antiarrhythmic agent.
  33. Molsidomine is an orally active, long acting vasodilating drug. Molsidomine is metabolized in the liver to the active metabolite linsidomine.
  34. Sucralfate is a sucrose sulfate-aluminium complex that binds to the ulcer, creating a physical barrier that protects the gastrointestinal tract from stomach acid and prevents the degradation of mucus.
  35. D panthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent.
  36. Oxybenzone is an organic compound used in sunscreens; provides broad-spectrum ultraviolet coverage, including UVB and short-wave UVA rays.
  37. Ademetionine disulfate tosylate is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases.
  38. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; component of a number of hair and skin conditioners.
  39. Dehydrocholic acid is a synthetic bile acid, manufactured by the oxidation of cholic acid.
  40. RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51.
  41. Sulisobenzone is an ingredient in some sunscreens which protects the skin from damage by UVB and short-wave UVA ultraviolet light.
  42. Glutathione acts as an antioxidant, a free radical scavenger and a detoxifying agent.
  43. L-tyrosine is a non-essential amino acid. In animals it is synthesized from Ephenylalanine.
  44. cell cycle inhibitor

    ON-013100 is a cell cycle inhibitor and is potentially useful for the treatment of mantle cell lymphoma.
  45. Fibrillogenesis inhibitor

    Eprodisate is an orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.
  46. SCH00013 is a cardiotonic agent that primarily acts via an increase in myofibrillar Ca++ sensitivity, have a significant Ca(2+)sensitizing effect at pH 7.2 to 7.4.
  47. VMAT2 inhibitor

    Valbenazine is a potent and selective VMAT2 inhibitor.
  48. Cytohesin inhibitor

    SecinH3 is a selective cytohesin inhibitor with IC50 of 2.4 μM, 5.4 μM, 5.4 μM, 5.6 μM, 5.6 μM, and 65 μM for hCyh2, hCyh1, mCyh3, hCyh3, drosophila steppke, and yGea2-S7, respectively.
  49. 3,3'-Diindolylmethane(DIM) is a major digestive product of indole-3-carbinol, a potential anticancer component of cruciferous vegetables.

Items 551-600 of 12610

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