Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Targeting the bacterial sliding clamp peptide 46 is a short peptide designed to inhibit the bacterial sliding clamp (SC). By interfering with SC-dependent DNA synthesis, this peptide serves as a valuable tool for studying bacterial replication mechanisms and developing novel antibacterial strategies. Its application in research underscores its potential utility in exploring bacterial growth and resistance pathways. -
Antimicrobial Peptide
CAP18 (rabbit) is an antimicrobial peptide comprising 37 amino acids, initially isolated from rabbit granulocytes. This peptide exhibits significant antimicrobial activity against both Gram-positive bacteria (IC50 130-200 nM) and Gram-negative bacteria (IC50 20-100 nM). CAP18 (rabbit) serves as a valuable tool in research focused on bacterial sepsis and the efficacy of antimicrobial agents. -
Antimicrobial Peptide
Bombinin-like peptide 3 is an antimicrobial peptide targeting bacterial membranes. Isolated from the skin secretions of the Asian toad Bombina orientalis, this peptide exhibits potent antibacterial activity. It is commonly used in research applications focusing on antimicrobial activity, peptide synthesis, and the development of novel antimicrobial agents. -
Antimicrobial Peptide
DRGN-1 is an antimicrobial peptide that demonstrates powerful antimicrobial and anti-biofilm properties, effectively targeting both Gram-negative and Gram-positive bacteria with an EC50 range of 0.50-4.62 μM. Its mechanism of action involves the disruption of bacterial membrane permeability and a slight depolarization of membrane potential. DRGN-1 also inhibits biofilm formation in both single and mixed species, including Pseudomonas aeruginosa and Staphylococcus aureus. Additionally, it has been shown to significantly enhance the healing process in uninfected and mixed biofilm-infected mouse wounds, making it a valuable reagent for research on infections. -
Antibacterial Peptide
Eumenitin is an antibacterial peptide targeting bacterial membranes, exhibiting broad-spectrum activity against both Gram-positive and Gram-negative bacteria with minimal hemolytic toxicity. It effectively induces the release of β-hexosaminidase from rat peritoneal mast cells and RBL-2H3 cells. Eumenitin is valuable for research into infectious diseases and the mechanisms of antibacterial action. -
Antibacterial Peptide
Oncocin is an antibacterial peptide belonging to the proline-rich antimicrobial peptide (PrAMP) class. It exhibits potent activity against Gram-negative bacteria, with minimal inhibitory concentrations (MIC) ranging from 0.125 to 8 μg/mL against various strains and clinical isolates of Enterobacteriaceae and non-fermenters. Oncocin targets the substrate-binding domain of the chaperone DnaK, leading to protein misfolding and aggregation, ultimately resulting in bacterial cell death. This mechanism makes Oncocin valuable for research into bacterial resistance and antimicrobial therapies. -
Antimicrobial Peptide
GVLSNVIGYLKKLGTGALNAVLKQ is an antimicrobial peptide known for its potent activity against both Gram-negative and Gram-positive bacterial strains, as well as the yeast Candida albicans. Comprising 24 amino acids, this peptide has the capacity to adopt an α-helical conformation, contributing to its membrane-disruptive properties. This characteristic makes it an invaluable tool in antimicrobial research and the development of novel therapeutic agents targeting resistant microorganisms. -
Antimicrobial Peptide
Bombinin-like peptide 2 is an antimicrobial peptide targeting microbial pathogens, sourced from the skin secretions of the Asian toad Bombina orientalis. This peptide exhibits significant antimicrobial activity against various bacteria and fungi, making it a valuable tool for research in infectious diseases and peptide-mediated immunity. Its unique properties facilitate investigations into peptide design and development for therapeutic applications against resistant microbial strains. -
Bioactive Peptide
CHRG01 is a bioactive peptide derived from the C-terminal amino acids 54 to 67 of human β-defensin 3 (hBD3), with all cysteine residues substituted with serine to eliminate disulfide bonding. This modification preserves the peptide's antimicrobial properties while enhancing its stability. CHRG01 exhibits electrostatic-dependent antimicrobial activity, making it a valuable tool for research applications involving antimicrobial peptides and immune response studies. -
Antimicrobial Peptide
AR-23 is an antimicrobial peptide derived from Rana tagoi, demonstrating a primary mechanism of action against various microbial targets. This peptide exhibits broad-spectrum inhibitory activity against aerobic bacteria, including clinical isolates of Methicillin-resistant Staphylococcus aureus (MRSA), as well as the opportunistic yeast pathogen Candida albicans. AR-23 is an invaluable tool for research applications focused on antimicrobial resistance and the development of new therapeutic agents. -
Antibacterial/Antitumoral Peptide
Dermaseptin-B3 is an antibacterial and antitumoral peptide that exhibits potent activity against both Gram-positive and Gram-negative bacteria, with minimum inhibitory concentrations (MIC) of 1.3 μM for Staphylococcus aureus, 2.3 μM for Pseudomonas aeruginosa, and varying concentrations for Escherichia coli strains (ATCC 25922: 5.0 μM; 54127: 2.6 μM). Additionally, Dermaseptin-B3 demonstrates the capability to inhibit tumor cell proliferation, making it a valuable reagent for research in antimicrobial and cancer studies. -
Polypeptide
LL-37 RKS is a synthetic polypeptide derived from the natural antimicrobial peptide LL-37. It exhibits notable antibacterial and antiviral activities, making it a valuable tool for investigating innate immune responses and host defense mechanisms. This fragment can be utilized in research focused on antimicrobial therapy, wound healing, and inflammatory responses. -
Antimicrobial Peptide
Cyclopetide 1 is an antimicrobial peptide that exhibits moderate activity against Bacillus subtilis, demonstrating a minimum inhibitory concentration (MIC) of 25 μg/mL. Its mechanism involves disrupting bacterial membranes, thus inhibiting cell growth. This compound is valuable for research applications focused on developing new antimicrobial agents and understanding peptide interactions with microbial targets. -
Antimicrobial Peptide
Brevinin-2 is an antimicrobial peptide targeting microbial pathogens with an ability to disrupt membrane integrity. Isolated from the skin secretions of the European green frog (Rana esculenta), this peptide exhibits broad-spectrum antibacterial and antifungal activity. Brevinin-2 is widely utilized in research applications focused on antimicrobial development and host defense mechanisms. -
Antimicrobial Peptide
Bombinin H5 is an antimicrobial peptide sourced from the skin of the European fire-bellied toad, Bombina variegata. This peptide demonstrates potent antimicrobial activity against a range of bacterial and fungal pathogens, making it a valuable tool for researching antimicrobial resistance and host-defense mechanisms. Its efficacy and mechanism of action provide insights into the development of novel therapeutic agents. -
Antibacterial Peptide
RT2 is a tryptophan-rich cationic amphipathic antibacterial peptide that primarily targets lipopolysaccharides (LPS) on bacterial surfaces and intracellular DNA. It binds to LPS and interacts with cytoplasmic membrane phospholipids, which facilitates rapid penetration of the bacterial cell membrane. Once inside, RT2 binds to cytoplasmic components, including DNA, to exert potent antibacterial activity. This peptide shows promise for research into acute and chronic infections caused by planktonic bacteria. -
Antimicrobial Peptide
DRAMP18563 (MAP-04-02) is a linear antimicrobial peptide that functions as a delivery vector for dual-ring peptide inhibitors, facilitating their access to the target sites within Gram-negative bacteria by overcoming the challenges posed by the outer membrane. This compound is valuable for investigating novel delivery strategies for peptide-based therapeutics, particularly in enhancing the efficacy of inhibitors that exhibit limited membrane permeability. Its unique properties make it a useful tool in antimicrobial research and peptide drug development. -
ComR Agonist
XIPSth peptide is a potent agonist of the streptococcal competence regulator ComR. This peptide facilitates bacterial competence by enhancing the uptake of genetic material, thereby promoting horizontal gene transfer. XIPSth peptide is valuable for research into bacterial infection mechanisms and the development of novel therapeutic strategies against streptococcal diseases. -
GarKS Peptide
Enterocin Hybrid 1 targets the GarKS peptide and acts as an antibacterial agent. It demonstrates effectiveness against Vancomycin-resistant Enterococcus faecium and Staphylococcus haemolyticus, making it a valuable reagent for studying antibiotic resistance and developing new therapeutic strategies. Its antibacterial properties provide essential insights into microbial inhibition and treatment approaches in infectious disease research. -
Antibacterial Peptide
Penta lysine is an antibacterial peptide that effectively targets multiple bacterial strains including E. coli, A. baumannii, P. aeruginosa, S. aureus, and B. subtilis. Its minimum inhibitory concentration (MIC) ranges from 1.1 to 18 μM, demonstrating significant antimicrobial activity. Penta lysine is valuable for research applications focused on developing new antibacterial therapies and understanding microbial resistance mechanisms. -
Antimicrobial Peptide
Maximin 7 is an antimicrobial peptide derived from the skin of the Bombina maxima toad. This peptide exhibits strong antimicrobial properties, effectively inhibiting a broad spectrum of bacterial and fungal pathogens. Maximin 7 is valuable for researchers investigating antimicrobial mechanisms, peptide-based therapeutics, and the development of novel antimicrobial agents. -
Cationic Antimicrobial Peptide
WLBU2 is an engineered cationic antimicrobial peptide (eCAP) that targets bacterial membranes, demonstrating rapid bactericidal activity. It exhibits minimum inhibitory concentration (MIC) values of ≤ 10 μM against a range of Gram-negative and Gram-positive bacteria, including MRSA and vancomycin-resistant enterococci. WLBU2 effectively prevents biofilm formation by Pseudomonas aeruginosa and retains antimicrobial efficacy in challenging environments such as high salinity and low pH, without compromising human airway epithelial cell viability. This reagent is valuable for research investigating cystic fibrosis and Pseudomonas aeruginosa infections. -
Antimicrobial Peptides
Bombolitin V is a potent antimicrobial peptide that targets mast cells to induce degranulation, exhibiting an ED50 value of 2 micrograms/ml. This peptide demonstrates significant antimicrobial activity, making it a valuable tool for research applications related to host defense mechanisms and the study of peptide-based therapeutics. -
Antimicrobial Peptide
BTM-P1 is an antimicrobial peptide that primarily targets bacterial membranes, demonstrating potent antibacterial activity against both Gram-positive and Gram-negative bacteria. Its mechanism involves the formation of ion-permeable channels in the inner mitochondrial membrane, leading to disruptions in mitochondrial energy processes. BTM-P1 is suitable for research applications focused on understanding antimicrobial mechanisms and investigating the potential therapeutic use of peptide-based antibiotics. -
Antimicrobial Peptide
Maximin H1 is an antimicrobial peptide that targets bacterial and fungal pathogens. Isolated from the skin secretions of the Chinese red belly toad (Bombina maxima), it exhibits potent activity against Escherichia coli ATCC25922, Staphylococcus aureus ATCC2592, Bacillus pyocyaneus CMCCB1010, and Candida albicans ATCC2002, with MIC values of 9, 4.5, 9, and 4.5 μg/ml, respectively. This compound is valuable for research in antimicrobial resistance and the development of novel therapeutic agents. -
Antimicrobial Peptide
XT-4 is an antimicrobial peptide derived from the skin secretions of Xenopus tropicalis, targeting bacterial membranes. It exhibits significant antimicrobial activity against Escherichia coli, with a minimum inhibitory concentration (MIC) of 18 μM. XT-4 is suitable for research applications focusing on antimicrobial mechanisms and the development of novel therapeutic agents against bacterial infections. -
Membrane-Penetrating Peptide
(RFR)4XB is a cationic membrane-penetrating peptide that facilitates the transport of therapeutic agents across the outer membrane of gram-negative bacteria. This peptide has been shown to effectively deliver antisense oligomers, enhancing their cellular uptake and bioactivity. Its unique properties make it a valuable tool for research applications focused on bacterial infection and gene regulation studies. -
Antimicrobial Peptide
PA2-GNU7 is an antimicrobial peptide (AMP) that demonstrates significant antimicrobial activity, exhibiting minimal inhibitory concentrations (MIC) of 2 μM, 1 μM, 2 μM, 2 μM, and 8 μM against Pseudomonas aeruginosa, Escherichia coli, Salmonella typhimurium, Staphylococcus aureus, and Candida albicans, respectively. This peptide selectively targets and rapidly kills Pseudomonas aeruginosa while preserving beneficial commensal bacteria. Notably, PA2-GNU7 enhances survival rates in mice infected with Pseudomonas aeruginosa, making it a valuable candidate for the development of therapeutic interventions against multidrug-resistant infections. -
Bioactive Peptide
SMAP-18 is a bioactive peptide that primarily targets microbial pathogens. As a truncated form of SMAP-29, this 18-amino acid peptide exhibits significant antimicrobial activity against Pseudomonas strains and other Gram-negative bacteria, including multidrug-resistant pathogens. Notably, SMAP-18 demonstrates higher cell selectivity and reduced hemolytic activity, making it a valuable tool for research in antimicrobial therapeutics and the study of host-pathogen interactions. -
Antimicrobial Peptide
Macropin (MAC-1 peptide) is an antimicrobial peptide derived from the venom of the solitary bee Macropis fulvipes. It demonstrates significant antibacterial activity against both Gram-positive and Gram-negative bacteria and exhibits antifungal properties as well as moderate hemolytic activity against human erythrocytes. Macropin serves as a valuable reagent for research focused on anti-infective therapeutics and the study of host-pathogen interactions. -
Antimicrobial Peptide
PGLa is a 21-residue antimicrobial peptide that belongs to the magainin family, originally derived from the skin secretions of frogs. This peptide exhibits significant antibacterial and antifungal activity by disrupting microbial membranes, making it a valuable tool for research in antimicrobial applications. PGLa is used to investigate mechanisms of peptide-mediated cell disruption and potential therapeutic uses in combating resistant pathogens. -
LCMV Glycoprotein Peptides Frgment
LCMV gp33-41 is a peptide fragment derived from the glycoprotein of the lymphocytic choriomeningitis virus (LCMV), specifically a carboxyl-extended 9-amino acid sequence. This peptide is restricted by MHC class I H-2Db molecules, facilitating its recognition and presentation to cytotoxic T lymphocytes. LCMV gp33-41 is pivotal for immunological research applications, including the study of T cell responses and viral pathogenesis. -
Peptide
Nucleoprotein (396-404) is a peptide fragment derived from the lymphocytic choriomeningitis virus (LCMV), specifically spanning amino acids 396 to 404. This peptide serves as the H-2D(b)-restricted immunodominant epitope, making it a valuable tool for studying virus-specific immune responses. Its applications include the investigation of T cell recognition and the development of vaccines or therapies targeting LCMV. -
Bioactive Peptide
LCMV-derived p13 epitope is a bioactive peptide that functions as an H-2Db restricted epitope. Comprising amino acids 61 to 80 of the lymphocytic choriomeningitis virus (LCMV) pre-glycoprotein polyprotein GP complex, this peptide plays a critical role in studying adaptive immune responses to viral infections. It is a valuable tool in immunology research, facilitating the investigation of T cell recognition and antiviral responses. -
Antigen Peptide
GP(33-41) is a 9-amino acid peptide derived from the GP1 epitope of the lymphocytic choriomeningitis virus. This peptide has been shown to effectively upregulate H-2Db molecules on the surface of RMA-S (Db Kb) cells, with a half-maximal effective concentration (SC50) of 344 nM. GP(33-41) is valuable for research applications in immunology, particularly in studies involving viral infections and T cell responses. -
Inducer Peptide
SppIP is a 19-amino acid peptide that serves as a crucial inducer for the production of Sakacin P. This peptide enhances the expression of specific genes involved in the biosynthesis of Sakacin P, a bacteriocin with antimicrobial properties. SppIP is employed in research exploring microbial physiology and the development of natural preservatives in food science. -
Antimicrobial Peptide
ε-Poly-L-lysine is an antimicrobial peptide primarily targeting a broad spectrum of microorganisms, including bacteria, yeasts, and molds. Due to its thermal stability and resistance to acidic conditions, it is widely utilized as a natural food additive and preservative in various food and beverage applications. Additionally, ε-Poly-L-lysine is suitable for incorporation into nanoparticles or nanofiber membranes, enabling targeted delivery and sustained antibacterial activity. Its properties also allow for use as a liposome stabilizer in drug delivery systems. -
Antimicrobial Peptide
Pexiganan is a synthetic analog of the antimicrobial peptide magainin 2, primarily targeting bacterial membranes to exert its antimicrobial effects. This compound demonstrates broad-spectrum activity against a variety of pathogens, making it a valuable tool for studying infectious diseases. Pexiganan is particularly relevant in research applications focused on diabetic foot ulcer infections and other wound-related infections, providing insights into potential therapeutic strategies. -
RVG Peptide
RVG (RVG29) is a peptide derived from Rabies Virus Glycoprotein that specifically binds to the α-7 subunit of nicotinic acetylcholine receptors (nAChRs) on neuronal cells. This interaction facilitates the enhanced delivery of Mycobacterium tuberculosis antigens to antigen-presenting cells, making RVG valuable for immunological research and vaccine development studies targeting tuberculosis. -
Antibacterial Peptide
Elf18 is a peptide fragment derived from the bacterial translation elongation factor Tu (EF-Tu), functioning primarily as an antibacterial agent. It is recognized by plant pattern recognition receptors, triggering an immune response that enhances plant resistance to various pathogens. This peptide is valuable for research applications focused on understanding and improving plant immune responses. -
Antimicrobial Peptide
TP4, an antimicrobial peptide derived from Nile tilapia, primarily targets bacterial membranes. It demonstrates significant inhibitory effects against a range of gram-positive and gram-negative bacteria, with minimum inhibitory concentrations (MIC) ranging from 0.03 to 10 μg/mL. Additionally, TP4 enhances immune responses and promotes intestinal health, while exhibiting antioxidant properties. Its potential anti-tumor effects are attributed to the induction of necrosis via mitochondrial dysfunction in cancer cells, making TP4 a valuable candidate for various biomedical research applications. -
Quorum Sensing Signal Peptide
Competence-Stimulating Peptide-2 (CSP-2) is a 17-amino acid quorum sensing signal peptide that targets the ComD2 receptor in Streptococcus pneumoniae, exhibiting an EC50 of 50.7 nM. CSP-2 plays a critical role in regulating bacterial behaviors such as competence development, virulence, and biofilm formation. This peptide is essential for studying the mechanisms of bacterial communication and the associated phenotypic responses that impact pathogenicity. -
Decapeptide
PBP10 is a decapeptide that selectively targets lipoteichoic acid (LTA), lipopolysaccharide (LPS), and phosphatidylinositol-4,5-bisphosphate (PIP2). This compound exhibits bactericidal properties, anti-inflammatory effects, and regulates actin assembly while inhibiting cell motility. PBP10 is useful for research investigating bacterial infections, microbe-induced inflammation, skin and soft tissue infections, and sepsis. -
Antimicrobial Peptide
H-Trp-Trp-Trp-OH is a synthetic tripeptide composed entirely of tryptophan residues, targeting microbial cells. It demonstrates significant antibacterial activity, making it a valuable reagent for studies in antimicrobial peptides. This compound can be utilized in research applications focused on the development of novel antimicrobial agents and the exploration of peptide-based therapies. -
Antibacterial Peptide
Cecropin P1, porcine is an antibacterial peptide primarily targeting Gram-negative bacteria. Isolated from the upper small intestine of pigs, this peptide exhibits significant antibacterial activity and also demonstrates antiviral properties, including inhibition of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection. Its applications are valuable in the research of antimicrobial agents and viral pathogenesis. -
Immunoactive Peptide
ESAT6 Epitope is an immunoactive peptide derived from the early secreted antigen target gene 6 (ESAT6), specifically designed to bind with high affinity to major histocompatibility complex (MHC) class I, exhibiting an IC50 of 180 nM. This epitope plays a crucial role in enhancing BCG-induced cellular immunity against Mycobacterium tuberculosis. It is valuable in studies focused on T cell-mediated immune responses and tuberculosis vaccine development. -
Antimicrobial Peptide
Tachyplesin I is a β-hairpin antimicrobial peptide composed of 17 amino acid residues. It demonstrates significant cytotoxic activity against various human tumor cell lines by disrupting the integrity of the outer cell membrane. This peptide is utilized in research investigating antimicrobial properties and potential therapeutic applications in cancer treatment. -
Antimicrobial peptide
LL-37 amide is an antimicrobial peptide that selectively targets the formyl peptide receptor-like FPRL1. It demonstrates significant bactericidal activity against periodontal pathogens with an ED99 value of 8.5-8.7 μg/mL by inducing immune cell chemotaxis and disrupting bacterial cell membranes. Additionally, LL-37 amide modulates inflammatory responses by inhibiting the release of pro-inflammatory factors such as TNF-α and promotes angiogenesis. Its amidation modification enhances stability and reduces serum sensitivity. This reagent is valuable for research in infection-related diseases, including periodontal disease, deep tissue injuries, and wound healing. -
Hemolytic Peptide
Delta-hemolysin is a 26 amino acid hemolytic peptide derived from Staphylococcus, known for its ability to interact with and perturb cellular membranes, potentially leading to cell lysis. This peptide serves as a valuable model for investigating the mechanisms of peptide-membrane interactions and studying membrane dynamics. Despite its hemolytic properties, Delta-hemolysin exhibits limited antibacterial activity. It is primarily utilized in research exploring peptide behavior and functions in membrane biology. -
Bioactive Peptide
PMAP-23 is a bioactive peptide that functions as an antimicrobial agent, derived from porcine myeloid tissues. This peptide exhibits significant antimicrobial activity against a range of bacteria and fungi, making it valuable for research in infectious disease and immunology. Its role in modulating immune responses also positions PMAP-23 as a potential candidate for studies focused on host defense mechanisms and therapeutic applications.
