NF-kB



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Catalog No. Product Name Application Product Information
A16301

(+)-DHMEQ

NF-kB inhibitor
The (+)-DHMEQ, the distomer of DHMEQ, is a inhibitor of NF-kB.
A16302

(-)-DHMEQ

NF-kB inhibitor
(-)-DHMEQ, the eutomer of DHMEQ , is a newly developed NF-kB inhibitor, inhibits nuclear factor kB activation with IC50 value of 20 ug/mL, the activity is stronger than (+)-DHMEQ (HY-14645A).
A11821

Bindarit

-
Bindarit is an anti-inflammatory small molecule that modulates the NFκB pathway.
A15046

CID-2858522

NF-κB inhibitor
CID-2858522 selectively inhibits the NF-??B pathway (IC50 < 0.1 uM for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways.
A10293

Deferasirox

Iron chelator
Deferasirox is a rationally-designed oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias.
A14142

JSH 23

NF-κB inhibitor
JSH 23 is an inhibitor of NF-??B, blocking its translocation into the nucleus (IC50 = 7.1 ?M)
A16306

Pyrrolidinedithiocarbamate ammonium

NF-kB inhibitor
Pyrrolidinedithiocarbamate ammonium is a selective NF-kB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.
A12748

QNZ (EVP4593)

NF-κB inhibitor
QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling.
A14278

SC75741

NF-κB inhibitor
SC75741 is a potent NF-??B inhibitor with EC50 of 200 nM.
A12669

Teglarinad chloride

-
Teglarinad chloride, also known as GMX1777, is a water-soluble prodrug of a cyanoguanidine compound with potential antineoplastic activity. In vivo, teglarinad chloride is rapidly converted into active drug through hydrolytic cleavage of a carbonate ester bond.

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