Withaferin A

Catalog No.: A16904

Steroidal Lactone

Withaferin A

Withaferin A Chemical Structure

CAS NO. 5119-48-2

Withaferin A is a steroidal lactone present in W. somnifera that at 2-25 μM has been shown to bind to and induce aggregation of vimentin intermediate filaments in cultured endothelial cells and fibroblasts, causing apoptosis.

Availability: In stock

Package Price Qty
1 mg
$80.00
2 mg
$140.00
5 mg
$280.00
50 mg
$1,500.00
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Biological Activity

Withaferin A is a steroidal lactone present in W. somnifera that at 2-25 μM has been shown to bind to and induce aggregation of vimentin intermediate filaments in cultured endothelial cells and fibroblasts, causing apoptosis.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.25 mL 106.25 mL 212.49 mL
0.5 mM 4.25 mL 21.25 mL 42.5 mL
1 mM 2.12 mL 10.62 mL 21.25 mL
5 mM 0.42 mL 2.12 mL 4.25 mL

*The above data is based on the productmolecular weight 470.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16904
M. Wt 470.6
Formula C28H38O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 5119-48-2
Synonyms WithaferinA, Withaferin-A, NSC 101088, NSC 273757
SMILES O=C/1O[[email protected]](CC(=C\1CO)\C)[[email protected]@H](C)[[email protected]]6CC[[email protected]@H]4[[email protected]]6(C)CC[[email protected]@H]3[[email protected]]5(C(=O)\C=C/[[email protected]](O)[[email protected]]52O[[email protected]@H]2C[[email protected]]34)C

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