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GS143

Catalog No.: A22702
IκBα ubiquitination inhibitor

GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation.

GS143
Grouped product items
Product Name Price Stock Qty
GS143 5mg
$90.00
In stock
GS143 10mg
$155.00
In stock
GS143 50mg
$460.00
In stock
GS143 100mg
$900.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription

GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation.
Product Information
Catalog Num A22702
Formula C28H19FN2O4
Molecular Weight 466.46
CAS Number 916232-21-8
SMILES FC(C=CC=C1)=C1C2=CC=C(O2)/C=C3C(CC4=CC=CC=C4)=NN(C5=CC=C(C(O)=O)C=C5)C\3=O
Synonyms GS 143,GS-143
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
NF-κB/IκB > NF-κB
NF-κB/IκB > IκK/IκB
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