Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
2,3’-Anhydrothymidine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, which leads to subsequent induction of apoptosis. This compound serves as a valuable tool in cancer research, contributing insights into therapeutic strategies for lymphoid cancers. -
Nucleoside Metabolite
20-Hydroxyleukotriene E4 is a nucleoside metabolite that plays a crucial role in the metabolism of leukotrienes. It is involved in various biological processes, including immune response modulation and inflammation. Research applications include investigations of inflammatory diseases and the elucidation of leukotriene signaling pathways. -
Purine Nucleoside Analog
N2-iso-Butyryl-8-azaguanosine is a purine nucleoside analog that demonstrates significant biological activity against indolent lymphoid malignancies. Its anticancer properties are attributed to the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for research applications in oncology and cancer treatment studies. -
Guanosine Analog
5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is a guanosine analog that primarily targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory activity, and in various animal models, it has been shown to induce type I interferons, leading to antiviral effects. Its role in modulating immune responses makes it a valuable tool for research applications focused on viral pathogenesis and immune activation. -
Purine Nucleoside Analog
1-(2,3-Dideoxy-β-D-erythro-hexopyranosyl)cytosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for investigations into therapeutic strategies targeting nucleoside metabolism and malignancy treatment. -
Purine Nucleoside Analog
2′-Deoxy-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is utilized for exploring therapeutic strategies and understanding the underlying biology of tumor progression. -
Purine Nucleoside Analog
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabino-6-azidouridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. This compound operates by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in cancer research and therapeutic studies. Its unique structural modifications enhance its efficacy as a research reagent in exploring mechanisms of cancer treatment. -
Uridine Analog
N3-[(Tetrahydro-2-furanyl)methyl]uridine is a uridine analog with potential antiepileptic properties. This compound is utilized in research to explore anticonvulsant and anxiolytic activities, making it a valuable tool for the development of new therapies. Additionally, it may contribute to the discovery of novel antihypertensive agents, expanding its application in cardiovascular research. -
Adenosine Analog
9-(2-Deoxy-β-D-threo-pentofuranosyl)-9H-purin-6-amine is an adenosine analog that primarily acts on adenosine receptors. This compound exhibits smooth muscle vasodilatory activity and has demonstrated potential in inhibiting the progression of various cancers. It serves as a valuable tool in biochemical research focusing on vascular biology and oncology. -
Purine Nucleoside Analog
2'-Deoxy-N2-isopropyl guanosine is a purine nucleoside analog that primarily targets DNA synthesis. It exhibits notable antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as apoptosis induction and DNA synthesis inhibition. This compound serves as a valuable tool for researchers investigating cancer biology and therapeutic strategies in oncology. -
Thymidine Analog
3'-O-Methyl-5-methyluridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This reagent is utilized for labeling cells and monitoring DNA synthesis, making it valuable for studies in molecular biology and genetic research. Its unique properties allow for enhanced tracking of nucleic acid dynamics in various cellular contexts. -
5'-dIMP Analogue
5'-dIMPS is an analogue of 5'-dIMP that serves as a potential substrate, competitive inhibitor, or regulator of enzymes that interact with 5'-dIMP. Its structural similarity allows it to modulate enzymatic activities involved in nucleotide biosynthesis pathways. This compound can be utilized in biochemical studies to explore enzyme mechanisms and regulatory processes within cellular metabolism. -
Purine Nucleoside Analog
2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside is a purine nucleoside analog that exerts its biological activity by inhibiting DNA synthesis and inducing apoptosis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its role as a nucleoside analog makes it a valuable tool for research in cancer biology and therapeutic development. -
Adenosine Analog
2-Amino-2′-O-(2-methoxy-2-oxoethyl)adenosine is an adenosine analogue targeting adenosine receptors. It exhibits smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. This compound is valuable for research applications focusing on vascular biology and cancer therapeutics. -
Purine Nucleoside Analog
N6-(4-Methoxybenzyl)-2’-C-methyl adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is particularly useful for studying the effects of purine analogs on tumor progression and therapeutic responses. -
Purine Nucleoside Analog
1,2-Di-O-acetyl-3,5-di-O-benzoyl-3-beta-C-methyl-D-ribofuranose serves as a purine nucleoside analog, primarily targeting DNA synthesis inhibition. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis and disruption of cellular proliferation, making it a valuable reagent for cancer research applications. -
Uridine Analog
4′-C-2-Propen-1-yluridine serves as a uridine analog, targeting pathways involved in neurological function. This compound exhibits potential antiepileptic properties and is instrumental in exploring anticonvulsant and anxiolytic activities. Additionally, it holds promise for the development of novel antihypertensive agents, making it a valuable tool in biomedical research. -
Purine Nucleoside Analog
4-Hydroxy-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog primarily targeting DNA synthesis pathways. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are attributed to mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for research in cancer biology and therapeutic development. -
5'-dGMP Analogue
5'-dGMPS is a 5'-dGMP analogue that serves as a potential substrate, competitive inhibitor, or regulator of enzymes that interact with 5'-dGMP. This reagent can be utilized in enzymatic assays to study the kinetics and mechanisms of nucleotide metabolism and signaling pathways. Research applications include investigating the role of 5'-dGMP in cellular processes and the development of therapeutic interventions targeting nucleotide-related pathways. -
Guanosine Analog
2'-F-2'-ara-N2-ibu-dG Phosphoramidite is a guanosine analog that targets Toll-like receptor 7 (TLR7) to exhibit immunostimulatory activity. It has been shown to induce type I interferons in certain animal models, resulting in antiviral effects. This compound is valuable for research applications focused on antiviral mechanisms and immune response modulation. -
Thymidine Analog
2'-Deoxy-2'-fluoro-5-hydroxymethyl arabinouridine is a thymidine analog that incorporates into DNA during replication. This compound demonstrates insertional activity, allowing for effective labeling of cells and monitoring of DNA synthesis. It serves as a valuable tool in molecular biology research, particularly for studies involving DNA dynamics and cellular proliferation. -
Purine Nucleoside Analog
2-Chloro-3'-deoxy-3'-fluoroadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aiming to understand nucleoside analog effects and therapeutic strategies for hematological cancers. -
Purine Nucleoside Analog
3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine is a purine nucleoside analog that exhibits significant antitumor activities. It primarily functions by inhibiting DNA synthesis and promoting apoptosis in various cancer cell types, making it especially relevant for research involving indolent lymphoid malignancies. This compound serves as a valuable tool for studying cancer biology and the development of targeted therapeutics. -
Purine Nucleoside Analog
1,2-Di-O-isopropylidene-3-O-methyl-D-ribofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications aimed at understanding cancer cell metabolism and therapeutics. -
Nucleoside Metabolite
5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole is a nucleoside metabolite that plays a critical role in cellular metabolism. It is involved in the synthesis and regulation of nucleotide pools, making it useful for studying metabolic pathways and nucleoside biosynthesis in various biological systems. This compound is valuable for research applications related to enzymatic activity and cellular signaling. -
Purine Nucleoside Analog
2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mode of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic studies. This compound is ideal for investigations into the mechanisms of tumorigenesis and the development of novel anticancer strategies. -
Uridine Analog
4’-C-Methyl-5-methoxyuridine is an analog of uridine, known for its potential antiepileptic properties. This compound can be utilized in research to investigate anticonvulsant and anxiolytic activities, as well as in the development of novel antihypertensive agents. Its structural modifications allow for the exploration of biological mechanisms related to uridine's effects in neurological and cardiovascular systems. -
Sterol Metabolite
7α,25-Dihydroxy-4-cholesten-3-one is a sterol metabolite that functions primarily as a modulator of various biological processes. This compound is formed through the 7α-hydroxylation and subsequent oxidation of 25-hydroxycholesterol, influencing cholesterol metabolism and immune response pathways. It is instrumental in research focused on lipid biology, neuroinflammation, and sterol-related signaling mechanisms. -
Nucleotide
Adenosine tetraphosphate is a natural nucleotide that plays a critical role in various biological processes. It has been shown to reduce intraocular pressure in normotensive rabbit eyes, making it a valuable compound for research into ocular health and related therapeutic applications. This reagent can be utilized in studies focusing on nucleotide signaling and its physiological effects. -
Purine Nucleoside Analog
5′-Azido-2′,5′-dideoxy-2′-fluorouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer properties are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules or reactive DBCO/BCN groups, respectively. These characteristics make it a valuable tool for various research applications in chemical biology and drug development. -
Hypoxanthine Analog
2-Chloro-6-methoxypurine riboside is a hypoxanthine analog known for its mechanism as a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. This compound exhibits cytoprotective properties by inhibiting PARP activity, thereby preventing peroxynitrite-induced mitochondrial depolarization and the subsequent production of superoxides. Its anti-inflammatory effects and role as an indicator of hypoxia make it valuable for research applications in cellular metabolism and oxidative stress studies. -
Nucleoside Metabolite
Demethylphosphinothricin is a nucleoside metabolite that functions as a potent inhibitor of glutamine synthetase. Its primary mechanism involves the inhibition of amino acid metabolism, leading to disruption of nitrogen assimilation in plants and some microorganisms. This compound is valuable in agricultural research for studying herbicide resistance and in biochemistry for exploring metabolic pathways related to amino acid biosynthesis. -
Adenosine Analog
2′-β-C-Methyl-2-methoxyadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits vasodilatory effects on smooth muscle and has demonstrated potential in inhibiting cancer progression. Its applications extend to research involving cardiovascular function and cancer biology, making it a valuable tool for exploring therapeutic strategies in these areas. -
Purine Nucleoside Analog
3’-β-Amino-2’,3’-dideoxy-5’-O-trityl-5-methyl uridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, contributing to the induction of apoptosis in cancer cells. This reagent is valuable for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
5-(2,3,5-Tri-O-benzyl-beta-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine is a purine nucleoside analog that demonstrates significant antitumor activity against indolent lymphoid malignancies. Its antineoplastic mechanisms involve inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at understanding the therapeutic potential of purine analogs in oncology. -
Adenosine Analog
N6-(4-Methoxybenzyl)adenosine is an adenosine analog that primarily acts as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for research in oncology and cardiovascular studies. Its unique structure enables investigations into adenosine signaling pathways and their implications in various biological processes. -
Adenosine Analog
N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine is an adenosine analog that primarily targets adenosine receptors. It exhibits significant vasodilatory effects on smooth muscle and has demonstrated potential in inhibiting cancer progression. This compound is valuable in research focused on vascular biology and cancer therapeutics, offering insights into adenosine receptor signaling pathways and their clinical implications. -
Purine Nucleoside Analog
2’-C-β-Methyl-4-deoxyuridine is a purine nucleoside analogue that inhibits DNA synthesis and induces apoptosis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. It is valuable in cancer research applications aimed at understanding the mechanisms of action of nucleoside analogues in tumor cell proliferation and survival. -
Purine Nucleoside Analog
2’-β-C-Methyl-5-fluorouridine is a purine nucleoside analog known for its antitumor properties. This compound exhibits significant biological activity by inhibiting DNA synthesis and inducing apoptosis, making it particularly valuable for the study of indolent lymphoid malignancies. Its applications extend to cancer research, where it can be utilized to explore therapeutic strategies and mechanisms underlying tumor progression. -
Purine Nucleoside Analog
2-Amino-2′-C-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, specifically targeting indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, providing insights into therapeutic strategies for lymphoid malignancies. -
Pyrimidine Nucleoside Analog
Methyl 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate is a pyrimidine nucleoside analog that targets nucleic acid synthesis pathways. This compound exhibits significant activities, including the inhibition of DNA and RNA synthesis, as well as antiviral and immunomodulatory effects. It is a valuable tool in the study of biochemical processes and the development of therapeutic agents in cancer and viral research. -
Thymidine Analog
5’(R)-C-Methyl-5-methyluridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound is valuable for labeling cells and monitoring DNA synthesis in various biological assays. Its unique structure allows for the exploration of nucleoside metabolism and the study of DNA-related processes in cellular systems. -
Purine Nucleoside Analog
6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog that targets nucleic acid synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research and therapeutic studies. -
Purine Nucleoside Analog
2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutic development for hematological malignancies. -
Cytidine Analog
N4-Methylarabinocytidine is a cytidine nucleoside analog that inhibits DNA methyltransferases, thereby affecting DNA methylation processes. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable for cancer research and studies on epigenetic regulation. Its role as a nucleoside analog provides a tool for exploring the mechanisms of DNA modification and gene expression control in various biological contexts. -
Purine Nucleoside Analog
5-(Furan-2-yl)-2'-O-methyl-5'-O-DMTr-uridine is a purine nucleoside analog designed to interfere with DNA synthesis and induce apoptosis in malignant cells. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, making it a valuable tool in cancer research. Its unique structural modifications enhance its efficacy as a pharmacological agent in studying cancer-related pathways and therapeutic interventions. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine functions as a purine nucleoside analog. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. The compound's mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic development. -
Cytidine Analog
1-(β-D-Xylofuranosyl)-5-methylcytosine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it a valuable tool in epigenetics research. It is suitable for studies investigating the role of DNA methylation in gene regulation and cancer biology. -
Purine Nucleoside Analog
3’-Azido-3’-deoxy-2-thiouridine is a purine nucleoside analog that exhibits significant anticancer activity primarily through the inhibition of DNA synthesis and the induction of apoptosis. This compound is particularly effective against indolent lymphoid malignancies, making it a valuable tool in cancer research. Additionally, it serves as a click chemistry reagent, featuring an azide group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. -
Purine Nucleoside Analog
5'-O-Triphenylmethyl-2'-deoxyuridine is a purine nucleoside analog recognized for its ability to inhibit DNA synthesis and induce apoptosis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. It serves as a valuable tool for researchers exploring therapeutic strategies in cancer treatment and mechanisms of nucleoside analogs in oncology.
