Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
2′,3′-O-Isopropylideneisocytidine is a purine nucleoside analog that exerts significant antitumor activity by targeting indolent lymphoid malignancies. This compound primarily functions through the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. Its unique mechanism highlights its potential in various therapeutic applications aimed at treating specific types of malignancies. -
Purine Nucleoside Analog
4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine is a purine nucleoside analog that exerts its effects primarily through the inhibition of DNA synthesis. This compound demonstrates notable antitumor activity, particularly against indolent lymphoid malignancies, and induces apoptosis in cancer cells. Its applications in research provide valuable insights into the mechanisms of cancer treatment and therapeutic resistance. -
Purine Nucleoside Analog
2’-Amino-2’-deoxy-5-methyl uridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound offers potential for exploring therapeutic strategies in oncology and advancing the understanding of nucleoside analog effects in tumor biology. -
Guanosine Analog
N1,N2-Dimethyl-2'-O-methylguanosine is a guanosine analog that primarily targets Toll-like receptor 7 (TLR7). It exhibits immunostimulatory activity and has been shown to induce type I interferons in various animal models, leading to significant antiviral effects. This compound is valuable in research applications focused on immune response modulation and the study of viral infections. -
Nucleoside Metabolite
22-Oxodocosanoic acid is a nucleoside metabolite that plays a critical role in cellular metabolism. It is involved in the regulation of fatty acid metabolism and may influence various biological processes such as cell signaling and energy homeostasis. This compound is suitable for research applications focusing on metabolic pathways and the study of nucleoside-related biological activities. -
Purine Nucleoside Analog
3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a purine nucleoside analog known for its potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound features an azide group, making it suitable for click chemistry applications, including copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing molecules, as well as DBCO or BCN groups. -
Nucleoside Metabolite
5-Hydroxykynurenine is a nucleoside metabolite that primarily functions as a precursor in the kynurenine pathway, influencing the balance of neuroactive metabolites. This compound exhibits bioactivity related to neuroprotection and modulation of neurotransmitter systems. It is commonly utilized in research focused on neurodegenerative diseases, psychiatric disorders, and inflammation studies, making it valuable for understanding neurochemical mechanisms. -
Purine Nucleoside Analog
2-Bromoadenosine is a purine nucleoside analog that exhibits potential antimalarial and anticancer activities. It is known to target indolent lymphoid malignancies through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. This compound is relevant for research applications focused on cancer therapy and elucidating the effects of purine analogs in cellular processes. -
Adenosine Analog
5'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite is an adenosine analog known for its role as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it valuable in various research applications related to cardiovascular health and oncology. Its structural properties allow for incorporation into oligonucleotides, facilitating studies on adenosine signaling pathways and therapeutic development. -
Antitumor Compound
LY207702 is a difluorinated purine nucleoside that exhibits antitumor activity primarily through cytotoxic effects on cancer cells. It demonstrates significant cytotoxicity against CEA-positive LS174T cells, with an IC50 value of 0.302 μg/mL. This compound is valuable for research applications in colon cancer studies, contributing to the understanding of therapeutic mechanisms and potential treatment strategies. -
Nucleoside Metabolite
(25S)-3Alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA is a nucleoside metabolite that plays a crucial role in lipid metabolism. This compound may participate in various biochemical pathways and can be utilized in research focused on cholesterol metabolism and related diseases. Its structural features suggest potential implications in studies of lipid biochemistry and cellular signaling. -
Purine Nucleoside Analog
2′,3′-Dideoxy-5-fluorouridine is a purine nucleoside analog that exerts its effects by inhibiting DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by promoting apoptosis and disrupting cellular proliferation. It serves as a valuable tool in cancer research, aiding in the understanding of therapeutic mechanisms and the development of novel treatments. -
Nucleoside Antimetabolite/Analog
Thiamiprine is a nucleoside antimetabolite and analog related to azathioprine, primarily targeting DNA synthesis. This compound exhibits cytotoxic effects in vitro, demonstrating activity comparable to its parent compound, though its arabinoside variant is inactive and non-toxic. In vivo studies using the rat adjuvant arthritis model indicate that the riboside and 2'-deoxyriboside forms are less active than the parent compound, while maintaining a distinct safety profile. Thiamiprine is valuable for research applications focused on immunosuppression and cellular proliferation. -
Purine Nucleoside Analog
9-(2-β-C-Methyl-β-D-ribofuranosyl)purine is a purine nucleoside analog that exerts its effects by targeting cellular pathways involved in DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and inhibiting cellular proliferation. It serves as a valuable tool for research applications in cancer biology and therapeutics development. -
Purine Nucleoside Analog
7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its biological activity includes inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized to study mechanisms of cancer cell proliferation and therapeutic resistance, contributing to the development of targeted cancer therapies. -
Purine Nucleoside Analog
3'-O-Methyl-2'-O-acetyl-5'-O-benzoyluridine is a purine nucleoside analog known for its broad antitumor activity against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, particularly in studying cell proliferation and the apoptotic pathways in lymphoid malignancies. -
Purine Nucleoside Analog
2-Trifluoromethyl adenosine is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Cytidine Analog
2',3',5'-Tri-O-benzoyl-5-azacytidine serves as a potent cytidine analog with a primary mechanism of inhibiting DNA methyltransferases. This compound demonstrates significant anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research and epigenetic studies. Its ability to interfere with DNA methylation processes positions it as an important reagent for investigating gene expression regulation and therapeutic interventions in oncology. -
Unsaponifiable Lipid
4α-Methylfecosterol is an unsaponifiable lipid that serves as a critical component in lipid metabolism studies. This compound exhibits unique biological activity by influencing membrane fluidity and cellular signaling pathways. It is valuable for research applications in lipid biochemistry, endocrinology, and the study of metabolic disorders. -
Thymidine Analog
5-(Hydroxymethyl)-2′,3′-O-(1-methylethylidene)uridine is a thymidine analog that integrates into replicated DNA. This compound demonstrates insertional activity, making it valuable for cell labeling and monitoring DNA synthesis. Its applications extend to research focusing on cellular proliferation and genetic analysis. -
Cytidine Analog
5-Methoxy cytidine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable in cancer research and epigenetics studies. Its unique properties enable investigations into the regulatory roles of DNA methylation in various biological processes and diseases. -
Nucleoside Analogue
1-(2,3,5-Tri-O-benzoyl-2-C-β-methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a nucleoside analogue targeting cellular enzymatic pathways. This compound exhibits potential antiviral and anticancer activity, making it a valuable tool for researchers studying nucleoside metabolism and related therapeutic applications. Its unique structural modifications enhance its stability and efficacy in various biological systems, facilitating investigations into nucleoside function and biochemistry. -
Purine Nucleoside Analog
3',4-Dideoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic interventions targeting nucleoside metabolism. -
Nucleoside Metabolite
5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde is a nucleoside metabolite that plays a critical role in metabolic pathways. This compound exhibits notable biological activity related to nucleoside metabolism, making it valuable for research in cellular processes and enzymatic reactions. It is particularly useful for studies focused on nucleoside regulation and metabolism in various biological contexts. -
Purine Nucleoside Analog
1-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that targets critical pathways in cancer cells. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as DNA synthesis inhibition and the induction of apoptosis. Its unique structural features make it a valuable tool in cancer research, particularly for investigating therapeutic strategies in lymphoid cancers. -
Nucleoside Metabolite
(R)-Ureidoisobutyric acid is a nucleoside metabolite that plays a crucial role in various biochemical processes. This compound serves as an important intermediate in nucleotide metabolism and is utilized in research focused on cellular signaling, metabolism, and nucleic acid biochemistry. Its ability to influence metabolic pathways makes it a valuable tool for exploring cellular functions and disease mechanisms. -
Purine Nucleoside Analog
2′-O-Methyl-2-amino-6-chloropurine riboside is a purine nucleoside analog that serves as an important tool in cancer research. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by interfering with DNA synthesis and inducing apoptosis in cancer cells. Its versatile applications in cellular and molecular biology make it a valuable reagent for studying therapeutic strategies against various malignancies. -
Guanosine Analog
2'-C-Methylguanosine is a guanosine analogue that primarily targets and activates Toll-like receptor 7 (TLR7). It exhibits significant immunostimulatory activity and has been shown to induce type I interferons in various animal models, leading to antiviral effects. This compound is valuable for research applications focused on exploring the immune response and antiviral mechanisms. -
Adenosine Analog
3'-β-C-Methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits biological activity as a smooth muscle vasodilator and has demonstrated potential in inhibiting cancer progression. It is useful in research applications focused on cardiovascular function and cancer biology. -
Purine Nucleoside Analog
4’-C-Methyl-4-deoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily functions by inhibiting DNA synthesis and inducing apoptotic pathways in cancer cells. Its research applications include exploring mechanisms of cancer treatment and evaluating therapeutic efficacy in oncology studies. -
Nucleoside Metabolite
(R)-2-Hydroperoxy-α-linolenic acid is a nucleoside metabolite that plays a crucial role in fatty acid metabolism. It exhibits notable biological activities, including modulation of oxidative stress and cell signaling pathways. This compound is particularly useful in research focused on lipid metabolism, cell function, and the effects of oxidative damage in various biological systems. -
Purine Nucleoside Analog
2'-Deoxy-2'-fluoro-6-S-Methyl-6-thio-ara-guanosine is a purine nucleoside analog that primarily targets nucleotide metabolism. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, facilitating the exploration of therapeutic strategies targeting purine metabolism. -
Purine Nucleoside Analog
5-Hydroxy-2'-O-methyluridine is a purine nucleoside analog that exhibits significant anticancer activity. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis in cancer cells, making it a valuable tool in research aimed at understanding treatments for indolent lymphoid malignancies. Its biological properties position it as a promising candidate for further investigation in cancer therapy development. -
Purine Nucleoside Analog
6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[1,2-c]pyrimidin-5-one is a purine nucleoside analog with promising antitumor activity against indolent lymphoid malignancies. Its cytotoxic effects primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound's unique structure allows for further exploration in the development of targeted therapies for various malignancies. -
Nucleoside Metabolite
4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoic acid is a nucleoside metabolite that plays a significant role in cellular metabolism. This compound is implicated in various biochemical pathways, including those involving nucleobase metabolism. Its biological activities make it valuable for research applications focused on enzymatic reactions related to nucleoside synthesis and regulation. -
Purine Nucleoside Analog
3’-N-Acetyl-3’-amino-3’-deoxyuridine is a purine nucleoside analog primarily involved in inhibiting DNA synthesis. This compound exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inducing apoptosis and impairing cellular proliferation, making it a valuable reagent for cancer research and therapeutic studies. -
Nucleoside Metabolite
3-Benzylmalic acid is a nucleoside metabolite that serves as a valuable intermediate in biochemical synthesis. It can be produced from 2-Benzylmalic acid via a hydroxyl isomerization reaction catalyzed by HphCD. This compound is utilized in various research applications, particularly in studies related to enzymatic reactions and metabolic pathways involving nucleoside derivatives. -
Purine Nucleoside Analog
5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studying mechanisms of cancer cell proliferation and developing therapeutic strategies targeting nucleoside metabolism. -
Purine Nucleoside Analog
3’,5’-Di-O-acetyl-2’-deoxy-N3-methyl uridine is a purine nucleoside analog that acts primarily by inhibiting DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include induction of apoptosis and disruption of cellular proliferation, making it a valuable reagent for research in oncology and molecular biology. -
Purine Nucleoside Analog
3'-Azido-3'-deoxy-N6-methyladenosine is a purine nucleoside analogue designed for research applications in cancer biology. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. Additionally, it serves as a versatile click chemistry reagent, featuring an azide group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules or DBCO/BCN-functionalized compounds, facilitating bioconjugation studies. -
Purine Nucleoside Analog
2′-Deoxy-2′-fluoro-N-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for researchers investigating therapeutic strategies and mechanisms of action in cancer biology. -
Nucleoside Metabolite
2-Methyl-1-hydroxypropyl-ThPP is a nucleoside metabolite that plays a critical role in nucleoside metabolism. This compound is involved in various biological processes and is essential for studying cellular metabolism pathways. Its applications extend to research on nucleoside-related signaling and metabolic regulation in various biological systems. -
Purine Nucleoside Analog
N4-Ethyl-2’-deoxycytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. The compound functions primarily by inhibiting DNA synthesis, leading to the induction of apoptosis in cancer cells. Its applications in research include exploring mechanisms of cancer cell proliferation and evaluating therapeutic strategies targeting nucleosynthesis pathways. -
Quercetin Metabolite
3α,7α,12α,26-Tetrahydroxy-5β-cholestane is a significant metabolite of Quercetin, functioning as a key marker in primary bile acid biosynthesis. This compound plays a crucial role in research related to atherosclerosis, providing insights into lipid metabolism and cardiovascular health. Its biological activities make it a valuable reagent for studying the effects of dietary flavonoids on cellular pathways. -
Nucleoside Metabolite
(S)-Ureidoglycolic acid is a substrate for the enzyme ureidoglycolate dehydrogenase, playing a critical role in purine metabolism pathways. As a member of the n-carbomoyl-α-amino acid class, it is essential for studies focused on nucleotide biosynthesis and related metabolic processes. This compound serves as a valuable research tool for understanding the biochemical intricacies of purine metabolism and its implications in various physiological contexts. -
Nucleoside Metabolite
Phosphonoformyl-CMP is a nucleoside metabolite that serves as an analogue of cytidine monophosphate. This compound is primarily utilized in studies of nucleotide metabolism and enzymatic activity related to nucleoside triphosphate synthesis. Its unique structure allows for exploration of biochemical pathways and interactions involving nucleotides, thereby informing research in molecular biology and pharmacology. -
Purine Nucleoside Analog
2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research. This reagent is suitable for studies focused on understanding tumor biology and developing therapeutic strategies targeting nucleoside pathways. -
Purine Nucleoside Analog
3'-Azido-3'-deoxy-5-trifluoromethyluridine is a purine nucleoside analogue primarily known for its broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized compounds. -
Purine Nucleoside Analog
5’-O-TBDPS-2,2’-anhydrouridine is a purine nucleoside analog that acts primarily by inhibiting DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism also includes the induction of apoptosis, making it a valuable tool for research focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
3-epi-Azido-3-deoxythymidine is a purine nucleoside analog known for its antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This reagent is suitable for studies exploring therapeutic strategies in oncology and the mechanistic understanding of tumor cell behavior.
