Catalog No.
Product Name
Application
Product Information
Citations
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Guanosine Analog
TLR7 Agonist 13 is a guanosine analog that activates Toll-like receptor 7 (TLR7), leading to immunostimulatory effects and the induction of type I interferons, which may confer antiviral properties. This compound is utilized in various research applications to study innate immune responses. Additionally, TLR7 Agonist 13 features an alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) for click chemistry, facilitating its incorporation into diverse bioconjugation strategies. -
Nucleoside Metabolite
2'-Deoxy-5-hydroxymethyl-CTP is a nucleoside metabolite that serves as a key substrate in nucleic acid synthesis and metabolism. Its unique hydroxymethyl modification imparts distinctive biochemical properties that can influence enzymatic activity. This compound is valuable for research into nucleoside analogs, metabolic pathways, and the synthesis of modified nucleotides for therapeutic applications. -
Nucleoside Compound
5-(N-Methyl-N-trifluoroacetyl)aminomethyl uridine is a nucleoside compound that serves as a versatile intermediate in nucleic acid chemistry. Its structural modifications provide insights into the mechanisms of nucleoside incorporation and metabolism. This compound is applicable in research areas involving RNA synthesis, enzymatic studies, and the development of nucleotide analogs for therapeutic applications. -
Purine Nucleoside Analog
N4-Benzoyl-2'-O-(2-methoxyethyl)cytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions by inhibiting DNA synthesis and inducing apoptosis in cancer cells. Research applications include studying its effects on cellular proliferation and evaluating its potential in cancer therapy. -
Purine Nucleoside Analog
8-Hydroxy-xyloguanosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at elucidating the roles of purine metabolism in cancer biology and exploring potential therapeutic applications. -
Purine Nucleoside Analog
2’-β-C-Ethynyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. Additionally, this compound features an alkyne group, enabling its use in click chemistry applications through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. -
Purine Nucleoside Analog
Uridine-5-oxyacetic acid is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for studies aimed at understanding the therapeutic potential of purine analogs in oncological applications. -
Nucleoside Metabolite
5-Hydroxyindolepyruvate is a nucleoside metabolite that plays a critical role in the metabolism of tryptophan. It has been shown to influence various biological pathways, including neurochemical signaling and cellular growth. This compound is used in research applications involving neurotransmitter synthesis and metabolic studies, providing insights into the physiological roles of indole derivatives. -
Purine Nucleoside Analog
4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its biological activity is primarily attributed to mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for researchers investigating cancer treatment and the underlying biology of nucleoside analogs in therapeutic applications. -
Purine Nucleoside Analog
5-Methoxy-4-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for research in cancer biology. This reagent is useful for studies exploring the effects of nucleoside analogs on cellular proliferation and programmed cell death. -
Purine Nucleoside Analog
N6-Isopentenyl-2’-deoxy adenosine, also known as 2’-deoxy riboprine, is a purine nucleoside analog that primarily targets DNA synthesis inhibition. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are attributed to mechanisms such as the induction of apoptosis and disruption of cell proliferation, making it a valuable reagent for cancer research applications. -
Purine Nucleoside Analog
5-Methyl-4-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer therapeutics and cell proliferation studies. This compound is useful for investigating the effects of purine metabolism and nucleoside analogs in various biological contexts. -
Thymidine Analog
2’,3’,5’-Tri-O-benzoyl-2’-β-C-methyl-5-methyl uridine is a thymidine analog that effectively incorporates into replicated DNA. This compound exhibits insertional activity, facilitating the labeling of cells for tracking DNA synthesis. Its unique structural modifications enable specific applications in molecular biology and genetic research, making it a valuable tool for studying DNA replication dynamics. -
Purine Nucleoside Analog
3′-Deoxy-3′-methylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studies aimed at understanding the molecular underpinnings of cancer and evaluating potential therapeutic strategies. -
Purine Nucleoside Analog
5'-Deoxy-5-methyluridine is a purine nucleoside analog known for its significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable in research aimed at elucidating mechanisms of cancer progression and developing novel therapeutic strategies. -
Thymidine Analog
5-Naphthyl-β-methylaminocarbony-3'-O-acetyl-2'-O-methyluridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound is effective for cellular labeling and monitoring DNA synthesis, making it valuable in molecular biology and genetics research. Its unique structure allows for optimized incorporation into nucleic acids, facilitating various applications in DNA manipulation and analysis. -
Guanine Nucleotide
Guanosine 5'-triphosphate 3'-diphosphate is a guanine nucleotide that serves as a crucial intermediate in RNA synthesis and protein synthesis mechanisms. By providing essential energy and phosphate groups, it facilitates cellular processes such as signal transduction and metabolic regulation. This compound is valuable for research applications focused on nucleic acid biochemistry and enzyme kinetics. -
Precursor of Trapping Product
15-Hydroxy-5,6-oxido-7,9,11,13-eicosatetraenoic acid is an important precursor in the biosynthesis of lipoxins in human leukocytes. This compound is integral in the formation of trapping products, which play critical roles in inflammatory processes and resolution mechanisms. It is utilized in research to elucidate the pathways involved in eicosanoid metabolism and the physiological implications of lipoxin signaling. -
Adenosine Analog
2'-Chloro-N6-benzyl adenosine is a chemically modified adenosine analog. This compound primarily functions as a smooth muscle vasodilator and exhibits potential inhibitory effects on cancer progression. Its unique structural properties make it a valuable tool for research in vascular biology and oncology, facilitating studies on adenosine signaling pathways and their implications in various physiological and pathological conditions. -
Purine Nucleoside Analog
7-n-Propyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in susceptible cancer cells. This compound serves as a valuable tool in cancer research, facilitating the exploration of therapeutic strategies targeting purine metabolism and cell proliferation. -
Nucleoside Metabolite
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine is a nucleoside metabolite that plays a vital role in bacterial cell wall biosynthesis. It serves as a precursor in the synthesis of peptidoglycan, making it essential for the integrity and maintenance of bacterial cell structure. This compound is particularly useful in research applications focused on understanding bacterial physiology, antibiotic development, and the mechanisms of resistance. -
Guanosine Analog
N-[2-[4-(1-Methylethyl)phenoxy]acetyl]guanosine is a guanosine analog that primarily targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory properties, leading to the induction of type I interferons in various animal models, thereby demonstrating significant antiviral effects. It serves as a valuable tool in research studies focusing on immune response modulation and antiviral therapies. -
Purine Nucleoside Analog
3’-O-MOE-5MeU-2’-phosphoramidite is a purine nucleoside analog that serves as a key reagent in nucleic acid synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms including the inhibition of DNA synthesis and the induction of apoptosis. Its utility in research includes applications in the development of therapeutic agents and the study of nucleic acid interactions. -
Purine Nucleoside Analog
2’-Deoxy-N4-ethyl-5-methylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions by inhibiting DNA synthesis and inducing apoptosis, thereby disrupting the proliferation of cancer cells. It serves as a valuable tool in cancer research, aiding in the study of nucleoside analog mechanisms and potential therapeutic applications. -
Purine Nucleoside Analog
3’-Deoxy-methyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications in cancer biology, enabling the exploration of therapeutic strategies targeting DNA replication and cellular survival pathways. -
Adenosine Analog
2-Amino-6-chloro-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-beta-D-ribofuranosyl)]-9H-purine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits biological activities such as promoting smooth muscle vasodilation and potentially inhibiting cancer progression. It is a valuable reagent for researchers investigating vascular biology, cancer therapeutics, and adenosine signaling pathways. -
Purine Nucleoside Analog
7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptotic pathways. This compound serves as a valuable tool in cancer research, facilitating studies on therapeutic strategies targeting nucleoside metabolism and cancer cell proliferation. -
Purine Nucleoside Analog
N6-iso-Propyladenosine is a purine nucleoside analog with significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for studying the effects of nucleoside analogs on cellular proliferation and apoptosis in various cancer models. -
Adenosine Analog
2-Amino-N-(3-methyl-2-buten-1-yl)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory activity and has been implicated in the inhibition of cancer progression. It serves as a valuable tool for research in vascular biology and cancer therapeutics, facilitating the exploration of adenosine receptor signaling pathways and their implications in various disease states. -
Uridine Analog
2′-Deoxy-2′-fluoro-5-methoxy-arabinouridine is a uridine analog that targets nucleotide metabolism. This compound exhibits potential antiepileptic properties and serves as a valuable tool for investigating anticonvulsant and anxiolytic activities. Additionally, it can be utilized in the development of novel antihypertensive agents, contributing to research in neurological and cardiovascular therapeutics. -
Nucleoside Metabolite
4α-Methyl-5α-ergosta-8,14,24(28)-trien-3β-ol is a nucleoside metabolite known for its role in cellular metabolism. This compound exhibits significant biological activity and is used in research applications focusing on metabolic pathways and nucleoside derivatives. Its unique structural properties make it a valuable tool for studying biochemical processes related to nucleoside function. -
Purine Nucleoside Analog
1,4-Anhydro-2,3-O-isopropylidene-5-O-t-butyldiphenylsilyl-4-thio-D-ribitol is a purine nucleoside analog that exhibits potent antitumor activity. This compound acts primarily by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in the study of indolent lymphoid malignancies. Its ability to mimic natural nucleosides allows for exploration in cancer research and therapeutic development. -
Cinnamic acid Derivative
Trans-2,3-Dihydroxycinnamate is a derivative of cinnamic acid that functions as a potent antioxidant. This compound exhibits significant biological activity that may contribute to its role in various biochemical pathways. It is useful in research applications focused on the investigation of antioxidant mechanisms and the metabolic effects of cannabinoids. -
Purine Nucleoside Analog
DMTr-TNA-C(Bz)-amidite is a purine nucleoside analog that serves as a critical component in nucleic acid synthesis. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research applications focused on therapeutic development and molecular studies. -
Purine Nucleoside Analog
N6-Methyl-2-methyl thioadenosine is a purine nucleoside analog that serves as a promising reagent in cancer research. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. Its mechanisms of action make it valuable for studying therapeutic strategies in oncology. -
Purine Nucleoside Analog
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, expanding its utility in chemical biology and drug development research. -
Purine Nucleoside Analog
5'-Azido-2',5'-dideoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is utilized for studying the effects of nucleoside analogs in cellular and molecular contexts related to oncogenesis and therapeutic resistance. -
Purine Nucleoside Analog
9-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. This compound impedes DNA synthesis and promotes apoptosis, contributing to its efficacy in cancer therapeutics. It is a valuable tool in research focused on understanding cancer biology and developing novel treatment strategies. -
Oligonucleotide
m7GpppCmpG is an oligonucleotide that serves as an M7GpppNpG trinucleotide cap analogue. This compound is essential for the synthesis of RNA molecules featuring cap 0 or cap 1 structures, facilitating studies in RNA biology and gene expression. It provides researchers with a valuable tool for exploring mRNA modifications and their implications in various biological processes. -
Guanosine Analog
N2-iBu-5’-O-DMTr-2’-O-propargylguanosine-3’-CED-phosphoramidite is a guanosine analog that serves as a critical tool for studying RNA synthesis and cellular responses. This compound exhibits immunostimulatory properties, with the potential to induce type I interferons in various animal models, contributing to antiviral effects. Its mechanism of action is linked to the activation of Toll-like receptor 7 (TLR7), making it valuable for research in immunology and antiviral therapeutics. -
Purine Nucleoside Analog
2-Amino-N,N-dimethyl-2′-C-methyladenosine is a purine nucleoside analog with significant biological activity against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aiming to elucidate the therapeutic potentials of nucleoside analogs in oncology. -
Glycoside
Nyasicoside is a norlignan glycoside with a primary mechanism targeting cardiac function. It exhibits significant antiarrhythmic activity, particularly in mitigating ouabain-induced arrhythmias in guinea pig heart preparations. This compound is valuable for research focused on cardiac physiology and the development of treatments for arrhythmias. -
Purine Nucleoside Analog
8-Chloro-2'-O-methyl adenosine is a purine nucleoside analog that exhibits potent antitumor activity. It primarily targets indolent lymphoid malignancies, utilizing mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research into cancer biology and therapeutic applications targeting malignancies. -
Adenosine Analog
5’-O-(4,4’-Dimethoxytrityl)-3’-O-t-butyldimethylsilyl adenosine is an adenosine analog that serves as a key modulator of adenosine receptors. This compound exhibits vasodilatory effects on smooth muscle and has potential applications in cancer research due to its ability to inhibit tumor progression. It is particularly useful for studies investigating the roles of adenosine in vascular biology and oncology. -
Purine Nucleoside Analog
N4-Benzoyl-7'-OH-N-trityl morpholino cytosine is a purine nucleoside analog that primarily targets DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and inhibiting cellular proliferation. This compound serves as a valuable tool in cancer research, facilitating the study of mechanisms underlying nucleotide metabolism and potential therapeutic interventions. -
Purine Nucleoside Analog
3’-beta-Azido-2’,3’-dideoxy-5’-O-(4-methoxy-trityl)uridine is a purine nucleoside analog that primarily targets DNA synthesis pathways. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms that include the inhibition of DNA synthesis and the induction of apoptosis. Its applications in chemical research may support the development of novel therapeutic strategies in oncology. -
Cytidine Analog
N4-Benzoyl-5’-O-DMT-3’-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog that functions as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor properties, making it valuable in cancer research. Its unique chemical structure enables investigations into epigenetic modifications and therapeutic approaches targeting DNA methylation pathways. -
Adenylate Cyclase Inhibitor
MANT-GppNHp is a competitive inhibitor of adenylate cyclase (AC) that serves as a fluorescently labeled GTP analogue. It specifically interacts with the hydrophobic pocket adjacent to the AC catalytic site through its MANT group, effectively obstructing the binding of ATP. This compound is valuable for investigating diseases characterized by elevated AC activity, such as cholera, and offers insights into cellular signaling pathways. -
Dideoxynucleotide
ddCTPαS is a dideoxynucleotide that acts as a chain-terminating nucleotide in DNA synthesis. Its primary application lies in DNA sequencing, where it facilitates the determination of nucleic acid sequences by preventing further elongation of the DNA strand during polymerization. Researchers utilize ddCTPαS to enhance the accuracy and efficiency of genetic analysis and sequencing methodologies. -
Cytidine Analog
2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable in cancer research. It is useful for studying epigenetic regulation and therapeutic strategies targeting methylation-driven processes in various malignancies.
