Catalog No.
Product Name
Application
Product Information
Citations
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Guanosine Analog
N2-iso-Butyroyl-5’-O-(4,4’-dimethoxytrityl)-3’-O-methylguanosine is a guanosine analog that primarily targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory activity and has the potential to induce type I interferons in various animal models, resulting in antiviral effects. Its mechanism of action makes it a valuable reagent for research applications related to immune response and antiviral drug development. -
Purine Nucleoside Analog
2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis in cancer cells, making it a valuable reagent for research in cancer therapeutics. Its unique structure allows for exploration in pharmacological studies and therapeutic applications targeting nucleoside metabolism. -
Dideoxynucleotide
ddGTPαS is a dideoxynucleotide analog that serves as a chain terminator in PCR assays. By incorporating ddGTPαS into the growing DNA strand, it inhibits further extension, allowing for precise control of amplification. This reagent is essential for applications in sequencing and studying DNA polymerization dynamics. -
Purine Nucleoside Analog
6-Methyl-9-(2-β-C-methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine is a purine nucleoside analog that exerts its effects by inhibiting DNA synthesis. This compound demonstrates notable antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the induction of apoptosis and disruption of cellular proliferation, making it a valuable tool for cancer research. -
Adenosine Analog
2-Amino-N6,N6-dimethyl-2’-O-methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory effects and has potential applications in inhibiting cancer progression. It is valuable for research in cardiovascular studies and oncology, providing insights into the therapeutic potential of adenosine-related pathways. -
Purine Nucleoside Analog
6-Methylpseudouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studies focused on cellular proliferation and apoptosis pathways in neoplastic cells. -
Adenosine Analog
3’-beta-C-Methyl-N6-methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. Its unique structure allows for various research applications, particularly in studies focusing on cardiovascular function and tumor biology. -
Purine Nucleoside Analog
8-Amino-2′-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound in cancer research. This reagent is suitable for exploring therapeutic strategies in nucleotide metabolism and evaluating potential treatments for lymphoid cancers. -
Cytidine Analog
5-Vinylcytidine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable in cancer research and therapeutic investigations. Its ability to alter epigenetic modifications positions it as a useful tool for studying gene regulation and methylation patterns in various biological contexts. -
Purine Nucleoside Analog
2'-Amino-2'-deoxy-5-fluoro-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis. This reagent is valuable for research in cancer biology and the development of novel therapeutic agents targeting nucleoside metabolism. -
Enzyme Substrate
Adenosine 5'-phosphosulfate serves as a substrate for bifunctional 3'-phospho-adenosine-5'-phosphosulfate synthases and related enzymes. This compound plays a critical role in sulfate activation and the synthesis of phosphoadenosine phosphosulfate, which is essential for sulfonate group transfers in biological systems. Its application in research includes studies on cellular sulfate metabolism and enzyme kinetics, providing insights into the regulation of various biochemical pathways. -
Purine Nucleoside Analog
5-Methyl-4'-thiocytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research by helping to elucidate the molecular pathways involved in tumor growth and resistance. -
Purine Nucleoside Analog
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focusing on nucleoside metabolism and the development of novel therapeutic strategies in oncology. -
Purine Nucleoside Analog
2-Amino-6-allyl thio-9-(beta-D-ribofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable tool for research applications focusing on cancer treatment strategies and the exploration of nucleoside analogs in therapeutic development. -
Purine Nucleoside Analog
2-Amino-2’,3’-bis-O-(2-methoxyethyl) adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer treatment and the exploration of nucleoside analogs in therapeutic development. -
Purine Nucleoside Analog
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine is a purine nucleoside analog with significant antitumor properties, specifically against indolent lymphoid malignancies. Its biological activity involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound in cancer research. This reagent can be utilized to explore mechanisms of action in cancer therapy and to evaluate its potential in drug development. -
Purine Nucleoside Analog
N2-Ethylguanosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. This compound exerts its anticancer effects through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. It serves as a valuable tool for research applications focused on cancer therapeutics and the study of nucleoside biochemistry. -
Purine Nucleoside Analog
2′-β-C-Methyl isoguanosine is a purine nucleoside analog that primarily targets nucleic acid synthesis pathways. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis in cancer cells. Its application in cancer research facilitates the exploration of therapeutic strategies for treating resistant forms of hematological malignancies. -
Purine Nucleoside Analog
2-Methyl-2’-deoxyadenosine is a purine nucleoside analog that exerts cytotoxic effects by inhibiting DNA synthesis. This compound is primarily investigated for its antitumor activity against indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis and disruption of cellular proliferation, making it relevant for cancer research applications. -
Purine Nucleoside Analog
2-Methylthio isopentenyladenosine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis in cancer cells. Its unique mechanism makes it a valuable tool for research into cancer therapies and mechanisms of cellular proliferation. -
Guanosine Analog
N2-iso-Butyroyl-2’-O-propargylguanosine is a guanosine analog that primarily targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory activity and has been shown to induce type I interferons in various animal models, contributing to antiviral effects. Additionally, it serves as a click chemistry reagent due to its alkyne functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating advanced biochemical research applications. -
Nucleoside Metabolite
3-Phospho-D-glycerate is an important nucleoside metabolite that serves as an intermediate in glycolysis and gluconeogenesis. It is converted to 2-phospho-D-glycerate (2-PGA) through the action of the enzyme phosphoglycerate mutase. This compound is significant for research in metabolism, cellular energy production, and enzyme kinetics. Its role in metabolic pathways makes it a valuable reagent for studies in biochemistry and molecular biology. -
Purine Nucleoside Analog
3′-Deoxy-3′-iodothymidine is a purine nucleoside analog that primarily targets DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by interfering with nucleotide metabolism and inducing apoptotic pathways in cancer cells. This compound serves as an essential tool for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-methyl-β-D-arabino-uridine is a purine nucleoside analog known for its antitumor activity. This compound targets indolent lymphoid malignancies through mechanisms that include the inhibition of DNA synthesis and the induction of apoptosis. Its unique structural modifications enhance its efficacy in cancer research applications. -
Purine Nucleoside Analog
2'-Deoxy-N6-phenoxyacetyladenosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic applications. This reagent is essential for studies focusing on the development of novel anticancer strategies and understanding the molecular pathways involved in tumorigenesis. -
Purine Nucleoside Analog
2’-Deoxy-2’-fluoro-arabino-tubercidine is a purine nucleoside analogue that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound serves as an important reagent for studying the pharmacological effects of purine analogs in therapeutic applications. -
Purine Nucleoside Analog
3’-Deoxy-3’-fluoro-5-methylcytidine is a purine nucleoside analog that demonstrates significant antitumor activity by targeting indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies investigating therapeutic strategies in oncology and the molecular mechanisms underlying lymphoid malignancies. -
Nucleoside Metabolite
Aldosterone hemiacetal is a nucleoside metabolite that serves as an important biologically active compound contributing to the understanding of steroid hormone signaling. This compound is utilized in research applications focused on aldosterone synthesis and its effects on mineralocorticoid receptors, thereby aiding in studies related to cardiovascular health and renal physiology. -
Thymidine Analog
5-(Azidomethyl) arauridine is a thymidine analogue that exhibits insertional activity into replicated DNA, making it valuable for labeling and tracking DNA synthesis in cellular studies. As a click chemistry reagent, it features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds possessing DBCO or BCN groups, expanding its utility in bioconjugation applications. -
Nucleoside Metabolite
L-Serine-phosphoethanolamine is a nucleoside metabolite that plays a crucial role in cellular signaling and phospholipid metabolism. It is involved in various biological processes, including the synthesis of phospholipids and neurotransmitters. This compound is valuable for research in cell biology, neurobiology, and metabolic studies, providing insight into the intricate network of cellular functions and signaling pathways. -
Purine Nucleoside Analog
6-(Thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for studying cancer biology and therapeutic interventions. This compound provides a critical tool for researchers investigating the effects of purine analogs in cancer treatment. -
Thymidine Analog
5-Carboxymethylaminomethyluridine is a thymidine analogue that exhibits insertional activity towards replicated DNA. This compound serves as a useful tool for labeling cells and studying DNA synthesis dynamics. Its applications in molecular biology can facilitate research in cellular proliferation and nucleotide metabolism. -
Purine Nucleoside Analog
5-Bromo-2'-O-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis. This compound is useful in cancer research for exploring therapeutic strategies targeting nucleoside metabolism and cancer cell proliferation. -
Guanosine Analog
8-Hydroxymethyl guanosine is a guanosine analog that acts as an immunostimulant. This compound has been shown to induce type I interferons in various animal models, leading to significant antiviral effects. Its functional activity is primarily mediated through the activation of Toll-like receptor 7 (TLR7), making it a valuable tool for research in immunology and antiviral therapies. -
Purine Nucleoside Analog
3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog that targets DNA synthesis. It exhibits significant antitumor activity against indolent lymphoid malignancies through mechanisms such as the inhibition of DNA replication and the induction of apoptosis. This compound is useful in cancer research and therapeutic studies focused on lymphoid malignancies. -
Nucleoside Metabolite
(S)-3-Hydroxytetradecanoyl-CoA primarily serves as a nucleoside metabolite involved in lipid metabolism. It plays a critical role in the biosynthesis of fatty acids and the regulation of energy homeostasis. This compound is relevant in studies focused on metabolic pathways and cellular energy regulation, making it a valuable tool for researching lipid-related disorders and metabolic diseases. -
Adenosine Analog
2’-O-Propargyladenosine is an adenosine analog that serves as a versatile click chemistry reagent due to its unique alkyne group. This compound exhibits smooth muscle vasodilatory effects and demonstrates potential for inhibiting cancer progression. Its ability to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) makes it an essential tool for bioconjugation applications in chemical biology research. -
Purine Nucleoside Analog
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinocytidine is a purine nucleoside analog with significant potential in cancer therapy. It exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in oncology and cancer treatment development. -
Purine Nucleoside Analog
N1-Cyclopropylmethylpseudouridine is a purine nucleoside analog that exhibits significant antitumor activity, specifically targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on understanding the cellular pathways involved in cancer progression and therapeutic response. -
Purine Nucleoside Analog
9-(2-β-C-Methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. This compound's anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. Its distinctive structural features allow for exploration in various nucleoside-related studies and therapeutic strategies. -
Purine Nucleoside Analog
N2,2'-O-Dimethylguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suited for investigations into therapeutic strategies and the underlying biology of malignant transformation. -
Purine Nucleoside Analog
Alpha-inosine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its therapeutic mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is useful in research applications focused on cancer biology and the development of novel therapeutic strategies. -
5-FU Precursor
Bis-Pro-5FU is a 5-Fluorouracil (5-FU) precursor designed to enhance oral bioavailability and improve the safety profile of 5-FU chemotherapy protocols. As an antineoplastic antimetabolite, 5-FU is commonly utilized in cancer research, particularly for colorectal and pancreatic cancer studies. Bis-Pro-5FU serves as a valuable tool for investigating more effective and safer treatment options in oncological research. -
Purine Nucleoside Analog
2'-Deoxy-2'-fluoro-4'-thio-β-D-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This reagent serves as a valuable tool for researchers investigating novel therapeutic strategies in oncology and elucidating the pathways involved in cancer cell proliferation and survival. -
Hypoxanthine Analog
2′-C-Methyl-6-O-methylinosine is a hypoxanthine analog that functions primarily by targeting metabolic pathways involving purines. This compound exhibits notable anti-inflammatory properties and has potential applications as an endogenous poly(ADP-ribose) polymerase (PARP) inhibitor, contributing to cytoprotection through the inhibition of PARP activity. Additionally, 2′-C-Methyl-6-O-methylinosine may serve as a valuable indicator of hypoxic conditions in various biological studies, facilitating research into cellular metabolism and stress responses. -
Purine Nucleoside Analog
6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine functions as a purine nucleoside analog. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms are primarily linked to the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in oncology and therapeutic applications targeting cancer cell proliferation. -
Nucleoside Metabolite
N(ω)-Hydroxyarginine is a nucleoside metabolite that serves as an intermediate in the metabolism of arginine. It is involved in various biological processes, including the regulation of nitric oxide synthase and the modulation of immune response. This compound is utilized in research applications focusing on nitric oxide synthesis, cardiovascular studies, and cellular signaling pathways. -
Nucleoside Metabolite
4-Guanidinobutanal is a nucleoside metabolite that acts as an important precursor in various biochemical pathways. This compound is utilized in research focused on nucleotide metabolism and can contribute to investigations into cellular processes such as energy production and signaling. Its role in nucleoside metabolism makes it a valuable reagent for studies in cell biology and biochemistry. -
Tryptophan Product
7,8-Dihydroxykynurenate is a key metabolite in the tryptophan metabolic pathway, acting as an agonist of the NMDA receptor. It has been shown to exhibit neuroprotective effects and can modulate glutamate activity, making it valuable for research in neurobiology and psychiatric disorders. This compound is useful in studying the role of tryptophan derivatives in cellular signaling and excitotoxicity. -
Purine Nucleoside Analog
N1-Benzyl pseudouridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. The compound operates primarily through the inhibition of DNA synthesis and the induction of apoptosis. Its biological activity makes it a valuable tool for research in cancer biology and the development of therapeutic strategies targeting nucleotide metabolism and tumor proliferation.
