Catalog No.
Product Name
Application
Product Information
Citations
- Dansyl chloride is a fluorescent labeling reagent that reacts with primary and secondary amines to form stable blue or blue-green fluorescent sulfonamide adducts. It readily labels aliphatic and aromatic amines through reaction with amino groups, making it a valuable tool for biochemical analysis. Dansyl chloride is widely used for amino acid derivatization, protein sequencing, and amino acid composition analysis, enabling sensitive fluorescence-based detection and quantification of amine-containing biomolecules.
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Fluorescent Tag
Ethidium bromide is a fluorescent intercalating agent widely used in molecular biology as a nucleic acid stain. It inserts between DNA base pairs, allowing visualization of DNA and RNA under ultraviolet (UV) light during techniques such as agarose gel electrophoresis. Due to its high sensitivity and strong fluorescence, Ethidium bromide is a standard tool for nucleic acid detection, though it is handled with caution because of its mutagenic properties. -
Fluorescent Dye
DiI is a long-chain lipophilic carbocyanine dye commonly used for fluorescent labeling of biological membranes. Due to its strong affinity for lipid bilayers, DiI efficiently integrates into cell membranes, making it ideal for tracing cells, organelles, liposomes, viruses, and lipoproteins. It exhibits bright fluorescence, high photostability, and minimal cytotoxicity, enabling long-term imaging and tracking in both fixed and live-cell applications. -
fluorescent probe
Coumarin 6 is a fluorescent dye commonly used as a probe in drug delivery research. It serves as a tracer in microparticle and nanoparticle delivery systems, enabling *in vivo* tracking, cellular uptake analysis, and transport mechanism studies. Coumarin 6 exhibits strong fluorescence with excitation and emission maxima at λexc = 450 nm and λem = 505 nm, respectively, making it an ideal marker for evaluating drug distribution and release profiles in biological systems. -
Fluorescent dye
PKH26 is a red fluorescent dye that stably incorporates into the lipid regions of the cell membrane, emitting red fluorescence (Ex/Em: 551/567 nm). It is commonly used for in vitro cell labeling, cell proliferation assays, and both in vivo and in vitro cell tracking studies. -
Fluorescent Dye
BODIPY 581/591 C11 is a boron-dipyrromethene (BODIPY) derivative with excellent photostability and minimal fluorescence artifacts. It is widely used to study lipid peroxidation and antioxidant activity in living cells, and to detect ferroptosis through its reaction with hydroxyl radicals. The dye exhibits a fluorescence shift upon oxidation: the reduced form emits at 591 nm (Ex: 581 nm), while the oxidized form emits at 510 nm (Ex: 500 nm). -
Mitochondrial Membrane Potential Fluorescent Dye
Rhodamine dyes are membrane-permeable, cationic fluorescent probes that selectively accumulate in mitochondria by sensing mitochondrial membrane potential, resulting in bright fluorescence. Due to their low cytotoxicity at appropriate concentrations, they are widely used for mitochondrial labeling in animal cells, plant cells, and microorganisms. -
Fluorescent Probe
DiO is a long-chain carbocyanine dye commonly used for labeling cells, organelles, liposomes, viruses, and lipoproteins. As a member of the Di-series carbocyanine dyes, DiO integrates into lipid membranes, enabling effective fluorescent tracking in various biological systems. -
fluorescent probe
RhoNox-1 is a fluorescent probe designed for the specific detection of divalent iron ions (Fe²⁺). Upon reaction with Fe²⁺, RhoNox-1 forms an irreversible orange-red fluorescent product (Ex/Em: 540/575 nm). It efficiently penetrates cell membranes and is suitable for detecting intracellular Fe²⁺, with a tendency to localize in the Golgi apparatus. - Calcein AM is a cell-permeable, non-fluorescent dye that readily enters live cells. Once inside, it is hydrolyzed by intracellular esterases to generate Calcein, a polar and highly negatively charged molecule that is retained within the cytoplasm. Calcein emits strong green fluorescence (Ex/Em: 494/515 nm) and is commonly used in combination with Propidium Iodide for assessing cell viability and cytotoxicity.
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Fluorescent Probe
Laurdan is a membrane-permeable fluorescent probe that exhibits spectral sensitivity to the phospholipid phase of the membrane it integrates into. Measurement of its generalized polarization (GP) enables quantification and distinction of membrane phases, such as liquid-ordered and liquid-disordered states. -
Mitochondrial Membrane Potential Fluorescent Dye
Rhodamine dyes are membrane-permeable, cationic fluorescent probes that selectively accumulate in mitochondria by recognizing mitochondrial membrane potential, producing bright fluorescence. At appropriate concentrations, they exhibit low cytotoxicity and are widely used for mitochondrial staining in animal cells, plant cells, and microorganisms. -
Fluorescent Dye
BODIPY-cholesterol is a lipophilic, cell-permeable fluorescent analog of cholesterol, labeled with a BODIPY fluorophore (Ex/Em: 505/515 nm). It is commonly used to monitor sterol uptake, distribution, and inter-organelle trafficking in live cells. -
Fluorescent Dye
Coppersensor-1 (CS1) is a membrane-permeable fluorescent probe with picomolar affinity for Cu⁺ ions, exhibiting high selectivity over other cellular metal ions. It enables sensitive and selective detection of copper(I) in biological samples, including live cells. CS1 is suitable for imaging studies related to copper homeostasis in diseases such as cancer, cardiovascular disorders, and neurodegenerative conditions. -
Red Fluorescent Dye
FM4-64 is a highly lipophilic, water-soluble styryl dye that selectively binds to the plasma membrane and internal membrane-bound organelles, producing bright fluorescence. It is widely used as a marker for endocytic and exocytic membrane structures in live-cell imaging studies. -
Fluorescent Dye
CellTracker Blue CMAC is a non-fluorescent, cell-permeable dye that becomes fluorescent upon enzymatic conversion by intracellular glutathione (GSH). The chloromethyl groups are cleaved to yield a blue fluorescent product (Ex/Em: 360/460 nm). It is suitable for long-term cell tracking (up to 72 hours), cell proliferation studies, and quantification of intracellular GSH levels. -
Fluorescent Probe
DiSC3(5) is a fluorescent probe commonly used to assess mitochondrial membrane potential, with excitation/emission maxima at 622/670 nm. It can inhibit mitochondrial NAD-linked respiratory activity, with an IC₅₀ of 8 μM. In the presence of the Na⁺/K⁺-ATPase inhibitor ouabain, DiSC3(5) induces membrane hyperpolarization in Ehrlich ascites tumor cells. -
Red Fluorescent Dye
MitoTracker Deep Red FM is a fluorescent dye that selectively accumulates in the mitochondrial matrix and covalently binds to mitochondrial proteins by reacting with free thiol groups of cysteine residues. This allows for stable mitochondrial labeling independent of membrane potential. The dye has excitation/emission maxima at 644/665 nm. Store protected from light. -
Cell Death Indicator
LysoTracker Red is a red-fluorescent lysosomal probe with excitation/emission maxima at 577/590 nm. It consists of a fluorophore linked to a weakly basic moiety, allowing it to freely cross cell membranes and selectively accumulate in acidic organelles such as lysosomes. LysoTracker Red is commonly used for visualizing lysosomal structures and studying lysosome-related biosynthesis and pathogenesis. -
Fluorescent Dye
Rhodamine dyes are membrane-permeable, cationic fluorescent probes that selectively accumulate in mitochondria by recognizing mitochondrial membrane potential. They generate bright fluorescence upon localization and exhibit low cytotoxicity at appropriate concentrations. Rhodamine dyes are widely used for mitochondrial staining in animal cells, plant cells, and microorganisms. -
Fluorochrome
1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe developed for the selective detection and quantification of hydrogen peroxide in the presence of various reactive nitrogen and oxygen species (RNOS). For nearly two decades, DPBF has been widely used as a specific indicator for reactive oxygen species, particularly singlet oxygen, hydroxyl radicals, alkoxyl radicals, and alkylperoxy radicals. -
RNA Aptamers Probe
DFHBI-1T is a membrane-permeable fluorescent probe activated by RNA aptamers, with excitation/emission maxima at 472/507 nm. It specifically binds to aptamers such as Spinach, Spinach2, iSpinach, and Broccoli, resulting in bright fluorescence with low background signal. DFHBI-1T is commonly used for live-cell imaging of RNA. -
DNA Fluorescent Stain
Hoechst 33342 trihydrochloride is a cell-permeable fluorescent dye from the Hoechst series, widely used as a live-cell nuclear marker. It binds preferentially to the minor groove of A/T-rich regions in double-stranded DNA, resulting in enhanced fluorescence intensity. Although it can associate with various nucleic acids, its fluorescence is significantly stronger upon binding to A/T-rich DNA. Hoechst 33342 is suitable for labeling live cells, and its fluorescence intensity increases with rising solution pH. -
Fluorescent dye
Rhodamine B is a fluorescent dye widely used for staining applications. It is commonly employed in the dyeing of textiles, paper, soap, leather, and various industrial agents. -
Endoplasmic Reticulum Fluorescent Dye
ER-Tracker dye is a BODIPY-based fluorescent probe conjugated with Glibenclamide, exhibiting high selectivity for the endoplasmic reticulum (ER). It is cell-permeable, non-toxic at low concentrations, and retains partial fluorescence after formaldehyde fixation. As an environment-sensitive dye, R-Tracker offers a long fluorescence lifetime and a high extinction coefficient. Glibenclamide, an ATP-sensitive K⁺ channel (Kir6.x, KATP) and CFTR Cl⁻ channel blocker, mediates ER targeting. R-Tracker is not suitable for post-fixation staining. -
Membrane Dye
DiR is a long-chain carbocyanine dye commonly used for labeling and tracking biological structures. As a member of the Di series of dyes, DiR is particularly suited for labeling cells, organelles, liposomes, viruses, and lipoproteins due to its strong membrane affinity and near-infrared fluorescence properties. -
Fluorescent Dye
IR780 is a prototypic near-infrared (NIR) heptamethine cyanine dye with a high molar extinction coefficient. It exhibits a maximum excitation wavelength of 777–780 nm and a maximum emission wavelength of 798–823 nm. IR780 is widely used in cancer research for photothermal therapy (PTT), photodynamic therapy (PDT), and imaging applications. -
Luciferin analogue
AkaLumine hydrochloride is a luciferin analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. It is commonly used in bioluminescence imaging and reporter assays for enhanced sensitivity and signal stability. -
Mitochondrial Dye
MitoTracker Green FM is a green fluorescent dye that selectively targets the mitochondrial matrix. It covalently binds to mitochondrial proteins through reaction with free mercaptan groups on cysteine residues, facilitating the visualization of mitochondrial structures independently of membrane potential. This dye is widely utilized in cellular and molecular biology research to study mitochondrial dynamics, function, and viability. Excitation and emission wavelengths are 490 nm and 523 nm, respectively. -
Green Fluorescent Dye
PKH 67 is a green fluorescent dye primarily used for staining cell membranes. With an excitation/emission range of 490/502 nm, it enables precise labeling of cells to facilitate studies of cell proliferation in vitro and tracking of cells in both in vitro and in vivo environments. This dye is commonly employed alongside the non-specific red fluorescent dye PKH26 to enhance multi-color cell analysis. -
Cellular Zinc Fluorescent Sensor
TSQ is a membrane-permeable fluorescent probe designed for the detection of zinc ions within cells, specifically targeting the cytosolic compartment. It exhibits a fluorescence emission maximum at approximately 495 nm when excited at 334 nm, enabling effective intracellular imaging of zinc-containing proteins. TSQ forms a complex with Zn2+ in the presence of Ca2+ and Mg2+, resulting in a distinctive blue fluorescence signal, making it a valuable tool for research applications involving cellular zinc dynamics and metalloprotein studies. -
Diazol Dye
Oil Red O is a fat-soluble diazol dye that primarily targets neutral lipids and cholesteryl esters, exhibiting maximum absorption at 518 nm. This reagent is widely utilized for the detection and quantification of hepatic steatosis in mouse liver biopsies, allowing for the visualization of significant metabolic changes in tissues. Oil Red O staining serves as an essential tool for researchers studying metabolic diseases and their progression. -
Fluorescent Dye
Thiazole Orange is a fluorescent dye primarily designed for nucleic acid detection. It exhibits significant fluorescence enhancement upon binding to DNA and RNA, making it ideal for applications such as biomolecular detection, gel staining, and reticulocyte analysis. This dye permeates living cell membranes and can be detected using ultraviolet or blue light, with an excitation maximum at 510 nm (also excitable at 488 nm and 470 nm) and an emission maximum at 527 nm. -
Fluorescent Probe
Acridine Orange 10-Nonyl Bromide is a fluorescent probe primarily targeting cardiolipin. This compound exhibits excitation maximum at 489 nm and emission maximum at 525 nm, making it suitable for studies involving mitochondrial function and apoptosis. It is widely used in various biological research applications, particularly in understanding membrane dynamics and cellular lipid interactions. -
Dye
Cyanine7 NHS ester tetrafluoroborate is a near-infrared fluorescent dye designed for biological conjugation applications. It exhibits strong fluorescence properties, making it ideal for imaging and labeling studies in fluorescence microscopy and flow cytometry. This reagent is particularly useful in labeling proteins and other biomolecules for enhanced visualization in various research contexts. -
Lipid Peroxidation Fluorescent Probe
LPd peroxida probe is a fluorescent marker specifically designed to detect lipid peroxidation, a key process in ferroptosis. This probe effectively converts lipid hydroperoxides into lipid alcohols, facilitating the imaging of lipid hydroperoxides in live cells. It is an invaluable tool for researchers exploring the implications of lipid peroxidation in various cellular pathophysiologies. -
Fluorescent Probe
Coumarin-SAHA is a fluorescent probe designed to investigate the binding affinities (kd) and dissociation off-rates (koff) of histone deacetylase 8 (HDAC8) inhibitor complexes. This compound is particularly valuable in research applications focused on epigenetic regulation and cancer biology. The fluorescent properties of Coumarin-SAHA enable real-time monitoring of molecular interactions, enhancing the understanding of HDAC functions and their role in disease mechanisms. -
Fluorescent Dye
WST-3 is a water-soluble tetrazolium dye that serves as a fluorescent probe for cellular activity. Upon reduction by NADH in the presence of an electron mediator, WST-3 is converted to WST-3 formazan, which exhibits a maximum absorption at 433 nm. This dye is widely utilized in cell viability assays and metabolic activity studies, making it a valuable tool for various biological and pharmaceutical research applications. -
Fluorescent Substrate APP+
IDT307 is a fluorescent substrate targeting the dopamine transporter (DAT). As an analog of the organic cation MPP+, it exhibits specific fluorescent properties that enable the visualization of DAT activity in various biological contexts. This compound is valuable for research applications focusing on dopamine signaling, drug interactions, and neurodegenerative disease models. -
Cetuximab-IRdye700DX Conjugate
Cetuximab sarotalocan is a conjugate of the anti-EGFR monoclonal antibody Cetuximab with the near-infrared photosensitizing dye IRdye700DX. This reagent is designed for applications in the research of head and neck cancers, specifically targeting epidermal growth factor receptors to facilitate imaging and therapeutic interventions. Its unique properties enable enhanced visualization in oncological studies, aiding in the exploration of tumor biology and treatment efficacy. -
Fluorescent Probe
ARHB is a selective and sensitive fluorescent probe targeting N-acetyltransferase 2 (NAT2), enabling real-time detection of NAT2 activity in various bacterial species. This probe effectively penetrates bacterial cells, with fluorescence intensity correlating positively with NAT2 expression levels. ARHB is particularly valuable for high-throughput screening of natural inhibitors aimed at combatting tuberculosis. -
Cationic Dye
Brilliant green is a cationic dye primarily utilized in the coloring of silk and wool. It exhibits antimicrobial activity by inhibiting the growth of Gram-positive bacteria, fungi, and certain intestinal parasites. This compound is also used in various biological research applications to study microbial resistance and the effects of dyes on cellular processes. -
Fluorescent Probe
PCL-2 is a reactive oxygen species-responsive fluorescent probe targeting hydrogen peroxide. It selectively reacts with hydrogen peroxide to produce 6-hydroxy-2-cyanobenzothiazole, exhibiting minimal response to other biologically relevant reactive oxygen species. PCL-2 is suitable for chemoselective imaging of hydrogen peroxide in in vitro models and can be applied in acute inflammation research using mouse models. This probe allows for the investigation of hydrogen peroxide's role in acute inflammatory processes. -
Fluorescent Probe
7-Hydroxy-4-methyl-2(1H)-quinolone is a fluorescent probe that effectively targets hydroxyl radicals. It plays a critical role in detecting DNA damage induced by oxidative stress, providing valuable insights into cellular damage mechanisms. This compound is utilized in various research applications, including studies focused on oxidative stress and DNA repair processes. -
Fluorescent Dye
C.I. Acid Yellow 151 is a fluorescent dye known for its strong adsorption properties. It is commonly used in various biological assays and microscopy applications to visualize cellular components. Additionally, C.I. Acid Yellow 151 can be effectively removed by bentone, making it suitable for various purification processes in chemical research. -
Fluorescent Dye
C.I. Acid Brown 83 is a fluorescent dye that exhibits strong adsorption properties. Its ability to bind and be removed by bentone clay makes it valuable in various analytical and biotechnological applications. This compound is commonly utilized in research involving fluorescence microscopy and dye-binding assays. -
Fluorescent Dye
C.I. Mordant Green 17 is a fluorescent dye characterized by its azo structure. It exhibits strong absorption and fluorescence properties, making it suitable for various biological staining applications. This dye is commonly used in histology and cytology for the visualization of cellular components, enabling researchers to study tissue morphology and cellular interactions effectively. -
Fluorescent Dye
C.I. Disperse Orange 37 is a fluorescent dye that primarily targets textiles and fibers for coloration. This vibrant orange dye exhibits high thermal stability and is frequently employed in the dyeing of synthetic fibers. Its ability to fluoresce under ultraviolet light makes it suitable for various applications in research, including studies on fiber characterization and tracing. -
Fluorescent Dye
Pigment Yellow 73 is a disazomethine dye primarily utilized as a fluorescent marker. This compound exhibits solid-state fluorescence, making it valuable for various biological research applications, including cell imaging and biosensing. Its unique fluorescent properties facilitate the visualization of cellular structures and processes, contributing to advancements in biochemical and molecular biology studies. -
Fluorescent Dye
C.I. Acid Red 138 is a fluorescent dye primarily utilized for its staining properties in various biological applications. It exhibits strong adsorption characteristics, enabling effective removal from different matrices using bentone clay. This compound is valuable in histology, cellular imaging, and as a tracer in biochemical assays, facilitating enhanced visualization and differentiation of biological samples.
